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Clinical Operations Manager Jobs (NOW HIRING)

DaVita, Inc.

Clinical Operations Manager

Forks, WA · On-site

Clinical Experience Required - Registered Nurse, Patient Care Technician, Licensed Social Worker, or Registered Dietician. What you can expect as a Healthcare Operations Manager: * Patients come ...

US Eye

Clinical Operations Manager

Fort Myers, FL · On-site

CLINICAL OPERATIONS MANAGER About US Eye: US Eye, is a physician-led, patient-centric network of eye care practices committed to providing exceptional patient service through premium technology and ...

Brooklyn Health

Clinical Operations Manager

Manhattan, NY · On-site

$90 - $130/hr

About the role We're hiring a Clinical Operations Manager to oversee eCOA deployments in CNS clinical trials. This position sits within the Operations team. It is an in-person role at our NoHo office.

Conduit Health

Clinical Operations Manager

New York, NY · On-site

$75K - $120K/yr

You partner naturally with Clinical Operations and report clearly to the Ops Manager on provider performance during and after onboarding. * Compliance-Minded: You understand healthcare regulations ...

Alcanza

Clinical Operations Manager

Sugar Land, TX · On-site

The Manager, Clinical Operations is responsible for leading the operational performance of the clinical research staff. Provides on-site oversight to help ensure execution and coordination of ...

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How much do clinical operations manager jobs pay per year?

As of Aug 29, 2026, the average yearly pay for clinical operations manager in the United States is $98,039.00, according to ZipRecruiter salary data. Most workers in this role earn between $72,500.00 and $113,500.00 per year, depending on experience, location, and employer.

What is a clinical operations manager?

Clinical Operations Managers are professionals responsible for overseeing the day-to-day administrative and operational functions of clinical trials or healthcare facilities. They ensure that clinical protocols are followed, resources are efficiently allocated, and regulatory compliance is maintained. These managers coordinate between healthcare staff, researchers, and external partners to facilitate smooth clinical operations and high-quality patient care. Their role is essential in ensuring that clinical services or trials are delivered effectively, safely, and on schedule.

What does a clinical operations manager do?

A clinical operations manager or director is a health care professional who oversees the operations of a medical facility. Their duties include meeting regularly with department heads, reading assessments of employee productivity, and managing administrative tasks, such as budgeting and billing. Qualifications for a clinical operations manager include experience in medical administration, management skills, and organizational skills. An advanced degree in public health or health administration can significantly improve your job opportunities.

What are the key skills and qualifications needed to thrive as a clinical operations manager, and why are they important?

To thrive as a Clinical Operations Manager, you need expertise in clinical trial management, regulatory compliance, and healthcare operations, usually supported by a degree in a health-related field and relevant experience. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) platforms, and certifications such as ACRP or SOCRA are commonly required. Strong leadership, problem-solving abilities, and effective communication are essential soft skills for this role. These skills ensure efficient trial execution, regulatory adherence, and successful coordination across teams and stakeholders.

What are the main challenges clinical operations managers face when overseeing multiple clinical trials simultaneously?

Clinical Operations Managers often juggle several clinical trials at once, which can present challenges such as maintaining consistent quality across studies, ensuring timely patient recruitment, and managing diverse teams. They must coordinate with cross-functional departments, address regulatory compliance, and troubleshoot unforeseen issues, all while staying on schedule and within budget. Effective organizational skills, proactive communication, and adaptability are essential for overcoming these challenges and ensuring successful trial outcomes.

What is the difference between Clinical Operations Manager vs Clinical Research Coordinator?

AspectClinical Operations ManagerClinical Research Coordinator
CredentialsBachelor's degree in health sciences, management experienceBachelor's degree in health or life sciences, research training
Work EnvironmentOversees multiple clinical trials, manages teamsAssists with daily trial activities, data collection
Employer & IndustryPharmaceutical companies, CROs, hospitalsResearch institutions, hospitals, clinical sites

The Clinical Operations Manager focuses on overseeing entire clinical trial operations, managing teams, and ensuring compliance. In contrast, the Clinical Research Coordinator handles the day-to-day activities at trial sites, such as patient recruitment and data collection. Both roles require related credentials and work within the clinical research industry, but their responsibilities and scope differ significantly.

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Clinical Operations Manager jobs near you
Infographic showing various Clinical Operations Manager job openings in the United States as of August 2026, with employment types broken down into 88% Full Time, 11% Part Time, and 1% Contract. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $98,039 per year, or $47.1 per hour.

Clinical Operations Manager

Martinez, CA • On-site

ExThera Medical
11 - 50 employees
Learn more about ExThera Medicalexternal

Full-time

Re-posted 28 days ago

Job description

A strategic and hands-on Clinical Operations Manager responsible for overseeing clinical trials for medical devices while driving process remediation and operational excellence. This role requires a creative, resourceful, and flexible leader who can prioritize effectively, build structure where needed, and ensure clinical studies are conducted in full compliance with applicable regulatory standards.
Clinical Trial Leadership & Execution
  • Manage sponsor-led clinical trials for medical devices across the U.S. and EU.
  • Ensure all clinical studies are conducted in adherence to study protocols, ICH/GCP guidelines, and region specific regulations.
  • Direct protocol development and finalization in collaboration with cross-functional teams.
Process Improvement & TMF Remediation
  • Assess, remediate, and optimize clinical processes and work instructions to align with regulatory requirements, industry best practices, and organizational needs.
  • Assess Trial Master File(s) against applicable regulations and industry best practices.  As needed remediate structure of Trial Master File(s) and as applicable records to ensure audit readiness/ preparedness across studies.
Regulatory & Compliance Oversight
  • Serve as point of contact for IRB/EC submissions and correspondence (including central IRBs).
  • Oversee the creation and execution of clinical trial activities in accordance with Good Clinical Practices. Ensure compliance of clinical trials with national and international regulatory requirements and co-monitoring the assigned clinical trial following company SOPs.
  • Oversee preparation and submission of study-level regulatory documents
  • Contribute to validation plans and clinical performance study plans.
  • Perform periodic QC of the TMF

Site & Study Management
  • Proactive identification and management of study related risks
  • Responsible for developing and managing study related plans, processes including; Investigator agreements (CTA), CRFs, monitoring plan, data management, safety monitoring
  • Lead development and management of clinical trial documents including (but not limited to) protocols, Case Report Forms (CRFs), consent documents, confidentiality agreements.
  • Contribute to site identification, feasibility, and selection for clinical studies.
  • Oversee site initiation, monitoring, and close-out activities (SQV, SIV, IMV, COV) as required.
  • Develop and deliver training materials for internal teams, CROs, and study sites (e.g., protocols, device training, SIV presentations).
Leadership & Communication
  • Provide regular clinical program updates to executive leadership and project teams.
  • Foster a culture of accountability and continuous improvement.
  • All other duties as assigned
Qualifications
  • Bachelor’s degree or equivalent in life science
  • Minimum of 7+ years preferred of clinical project management experience in conducting clinical trials in sponsor medical device organization, preferably Class III devices
  • A solid understanding of the ICH guidelines/GCP
  • Experience interacting with regulators, including FDA
  • Ability to travel to visit clinical sites and for study meetings. Amount will vary upon project needs
  • Demonstrated ability to lead teams and work in a fast-paced team environment
  • Ability to successfully engage and work collaboratively with sites and internal teams
  • Excellent written and oral communication skills
     

 

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