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Remote Senior Director Clinical Operations Jobs (NOW HIRING)

Noom US

Senior Director, Clinical Operations

New York, NY · On-site +1

$225K - $265K/yr

About the Role As we continue to grow, we're seeking a Senior Director, Clinical Operations to lead ... With a strong remote culture, as well as offices in NYC and Princeton, we've been named one of the ...

Ascension

Senior Director Clinical Operations

$193K - $328K/yr

Remote with some travel Department/Specialty: Neurosciences Service Line Schedule: Days | Full-time ... Medical Director and executive teams to merge clinical insights with operational strategy ...

AMSURG

Director, Clinical Operations

Director, Clinical Operations Remote Company Overview: AMSURG is an independent leader in ... Provides timely and comprehensive updates to Clinical Quality Sr. Leadership regarding status of ...

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Remote Senior Director Clinical Operations information

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How much do remote senior director clinical operations jobs pay per year?

As of Jun 14, 2026, the average yearly pay for remote senior director clinical operations in the United States is $145,969.00, according to ZipRecruiter salary data. Most workers in this role earn between $102,000.00 and $173,500.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Remote Senior Director Clinical Operations, and why are they important?

To thrive as a Remote Senior Director Clinical Operations, you need extensive experience in clinical trial management, regulatory compliance, and leadership, usually backed by an advanced degree in life sciences or healthcare. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) platforms, and relevant certifications like PMP or ACRP is highly valuable. Outstanding skills in strategic planning, communication, and cross-functional team leadership differentiate top performers in this role. These competencies ensure effective oversight of complex clinical programs, regulatory adherence, and successful collaboration across remote teams.

What does a Remote Senior Director of Clinical Operations do?

A Remote Senior Director of Clinical Operations oversees clinical trials and research operations, ensuring studies are conducted efficiently and in compliance with regulatory standards—all while working remotely. They lead cross-functional teams, manage budgets, develop operational strategies, and act as a liaison between internal teams and external partners. This leadership role requires a strong background in clinical research, excellent communication skills, and the ability to manage complex projects across multiple locations.

How does a Remote Senior Director Clinical Operations effectively manage and support geographically dispersed clinical teams?

As a Remote Senior Director Clinical Operations, you will leverage digital collaboration tools, regular virtual meetings, and clear communication protocols to oversee and support teams across multiple locations. Success in this role often involves establishing standardized processes, fostering a collaborative culture despite distance, and ensuring alignment with clinical trial objectives. You will also need to address challenges such as time zone differences and maintaining engagement, while providing leadership on trial execution, compliance, and quality metrics. Building strong relationships with cross-functional partners and implementing robust performance monitoring are essential for driving successful clinical operations remotely.

What is the difference between Remote Senior Director Clinical Operations vs Clinical Project Manager?

AspectRemote Senior Director Clinical OperationsClinical Project Manager
CredentialsAdvanced degrees (e.g., MD, PhD, or PharmD), extensive industry experienceBachelor's or Master's in life sciences, relevant project management certifications
Work EnvironmentStrategic leadership, overseeing multiple projects and teams remotelyManaging individual clinical trials, coordinating project activities
Employer & Industry UsagePharmaceutical companies, biotech firms, CROsPharmaceutical companies, CROs, clinical research organizations

The Remote Senior Director Clinical Operations focuses on strategic oversight and leadership of clinical programs at a high level, often managing teams remotely. In contrast, a Clinical Project Manager handles the day-to-day management of specific clinical trials, ensuring project milestones are met. Both roles require industry experience, but the senior director role involves broader oversight and strategic planning.

More about Remote Senior Director Clinical Operations jobs
What cities are hiring for Remote Senior Director Clinical Operations jobs? Cities with the most Remote Senior Director Clinical Operations job openings:
What states have the most Remote Senior Director Clinical Operations jobs? States with the most job openings for Remote Senior Director Clinical Operations jobs include:
What job categories do people searching Remote Senior Director Clinical Operations jobs look for? The top searched job categories for Remote Senior Director Clinical Operations jobs are:
Remote Senior Director Clinical Operations jobs near you
Infographic showing various Remote Senior Director Clinical Operations job openings in the United States as of June 2026, with employment types broken down into 68% Full Time, 22% Part Time, and 10% Contract. Highlights an 87% Physical, 5% Hybrid, and 8% Remote job distribution, with an average salary of $145,969 per year, or $70.2 per hour.
Sr. Director Clinical Operations

Sr. Director Clinical Operations

Scientific Search

Boston, MA • Remote

$250K/yr

Other

Posted yesterday

Job description

Senior Director, Clinical Operations – GI
Location: Remote
Reports to: Vice President Clinical Operations
Salary: $210-250k base plus bonus and equity
Join a well-funded, clinical-stage biotechnology company advancing innovative therapies for patients with serious immunology and inflammatory diseases. Backed by significant long-term investment and led by an experienced team with a track record of successfully developing and commercializing medicines, this organization combines the scientific rigor of large pharma with the agility and speed of a biotech startup. With multiple programs advancing across respiratory and gastrointestinal indications, this is a unique opportunity to play a highly visible leadership role and directly impact the development of potentially transformative therapies.
Position Summary
The Senior Director, Clinical Operations will provide strategic and operational leadership across gastrointestinal clinical development programs, overseeing the execution of Phase 1–3 clinical trials. This individual will partner closely with executive leadership and cross-functional teams to drive study execution, vendor oversight, and operational excellence while helping build scalable processes to support future growth.
Key Responsibilities
  • Lead operational strategy and execution for Phase 1–3 GI clinical trials.
  • Oversee study timelines, budgets, enrollment plans, and key milestones to ensure successful delivery.
  • Manage CROs and external vendors, establishing clear expectations, KPIs, and accountability.
  • Identify and mitigate operational risks while maintaining compliance with ICH-GCP and regulatory requirements.
  • Partner cross-functionally with Clinical Development, Biometrics, Regulatory, Medical Writing, Clinical Supply, and Quality to ensure seamless trial execution.
  • Contribute operational expertise to protocol development, study feasibility, and development planning.
  • Drive inspection readiness and maintain high-quality standards throughout study conduct.
  • Support the continued evolution of Clinical Operations infrastructure, processes, and best practices within a growing biotech environment.
  • Mentor team members and help foster a collaborative, high-performance culture.
  • Present program updates, milestones, risks, and operational strategies to senior leadership.
Requirements
  • Bachelor’s degree required; advanced scientific or healthcare degree preferred.
  • 8+ years of clinical operations experience within biotech, pharmaceutical, or CRO environments.
  • Experience leading Phase 1–3 clinical trials.
  • GI, immunology, inflammation, or related therapeutic area experience strongly preferred.
  • Proven CRO and vendor management experience.
  • Strong understanding of ICH-GCP, FDA regulations, and global clinical trial execution.
  • Demonstrated success operating within fast-paced biotech environments.
  • Excellent leadership, communication, and cross-functional collaboration skills.
  • 5+ years of people management experience preferred.
  • Ability to travel up to 20%.
Why This Opportunity?
  • High visibility role with direct interaction with executive leadership.
  • Opportunity to shape and build clinical operations infrastructure in a rapidly growing organization.
  • Strong financial backing and commitment to advancing innovative therapies.
  • Expanding pipeline focused on areas of significant unmet medical need.
  • Fully remote work environment with meaningful influence on corporate and clinical strategy.
How To Apply
We’d love to see your resume, but we don’t need it to have a conversation.
Email tom@scientificsearch.com or message me directly if you’d like to learn more.

Apply