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Remote Senior Director Clinical Operations Jobs (NOW HIRING)

Whoop

Director, Clinical Operations

Boston, MA · On-site +1

As the Director, Clinical Operations, you will lead the clinical operations function responsible ... ePRO, eTMF, and remote study platforms. * Oversee study startup and regulatory operations ...

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Liquidia Corporation

Director, Clinical Operations

Job Summary The Director, Clinical Operations will oversee the planning, execution, and delivery of ... This position is remote or office-based, depending on location. Travel may be required as needed to ...

Karoo Health

Director, Clinical Operations

Denver, CO · On-site +1

The Role The Director of Clinical Operations will lead the development, refinement, and execution ... Fully-remote work environment available * Full benefits package * A collaborative and transparent ...

Ossium Health

Clinical Trial Manager

San Francisco, CA · On-site +1

$145K - $165K/yr

This role reports to the Senior Director, Clinical Operations. Required Qualifications * Degree in ... as a remote work day * Ability to travel as needed (10% - 15%) * Qualified candidates must be ...

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Remote Senior Director Clinical Operations information

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How much do remote senior director clinical operations jobs pay per year?

As of Jun 10, 2026, the average yearly pay for remote senior director clinical operations in the United States is $145,969.00, according to ZipRecruiter salary data. Most workers in this role earn between $102,000.00 and $173,500.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Remote Senior Director Clinical Operations, and why are they important?

To thrive as a Remote Senior Director Clinical Operations, you need extensive experience in clinical trial management, regulatory compliance, and leadership, usually backed by an advanced degree in life sciences or healthcare. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) platforms, and relevant certifications like PMP or ACRP is highly valuable. Outstanding skills in strategic planning, communication, and cross-functional team leadership differentiate top performers in this role. These competencies ensure effective oversight of complex clinical programs, regulatory adherence, and successful collaboration across remote teams.

What does a Remote Senior Director of Clinical Operations do?

A Remote Senior Director of Clinical Operations oversees clinical trials and research operations, ensuring studies are conducted efficiently and in compliance with regulatory standards—all while working remotely. They lead cross-functional teams, manage budgets, develop operational strategies, and act as a liaison between internal teams and external partners. This leadership role requires a strong background in clinical research, excellent communication skills, and the ability to manage complex projects across multiple locations.

How does a Remote Senior Director Clinical Operations effectively manage and support geographically dispersed clinical teams?

As a Remote Senior Director Clinical Operations, you will leverage digital collaboration tools, regular virtual meetings, and clear communication protocols to oversee and support teams across multiple locations. Success in this role often involves establishing standardized processes, fostering a collaborative culture despite distance, and ensuring alignment with clinical trial objectives. You will also need to address challenges such as time zone differences and maintaining engagement, while providing leadership on trial execution, compliance, and quality metrics. Building strong relationships with cross-functional partners and implementing robust performance monitoring are essential for driving successful clinical operations remotely.

What is the difference between Remote Senior Director Clinical Operations vs Clinical Project Manager?

AspectRemote Senior Director Clinical OperationsClinical Project Manager
CredentialsAdvanced degrees (e.g., MD, PhD, or PharmD), extensive industry experienceBachelor's or Master's in life sciences, relevant project management certifications
Work EnvironmentStrategic leadership, overseeing multiple projects and teams remotelyManaging individual clinical trials, coordinating project activities
Employer & Industry UsagePharmaceutical companies, biotech firms, CROsPharmaceutical companies, CROs, clinical research organizations

The Remote Senior Director Clinical Operations focuses on strategic oversight and leadership of clinical programs at a high level, often managing teams remotely. In contrast, a Clinical Project Manager handles the day-to-day management of specific clinical trials, ensuring project milestones are met. Both roles require industry experience, but the senior director role involves broader oversight and strategic planning.

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What cities are hiring for Remote Senior Director Clinical Operations jobs? Cities with the most Remote Senior Director Clinical Operations job openings:
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Remote Senior Director Clinical Operations jobs near you
Infographic showing various Remote Senior Director Clinical Operations job openings in the United States as of June 2026, with employment types broken down into 68% Full Time, 22% Part Time, and 10% Contract. Highlights an 87% Physical, 5% Hybrid, and 8% Remote job distribution, with an average salary of $145,969 per year, or $70.2 per hour.
Director, Clinical Operations

Director, Clinical Operations

Whoop

Boston, MA • On-site, Remote

Full-time

Posted yesterday

Job description

As the Director, Clinical Operations, you will lead the clinical operations function responsible for executing the studies that support WHOOP's regulated and unregulated health features, with a particular focus on Software as a Medical Device (SaMD). You will own operational strategy and study execution across the product lifecycle, from early concept and feasibility through validation, regulatory submission, launch, and post-market evidence generation.

This role requires deep expertise in clinical trial operations, decentralized clinical trials, vendor oversight, and operational execution within regulated healthcare environments. As both a strategic leader and hands-on expert, you will oversee studies conducted through CROs as well as internally executed studies, ensuring high-quality, efficient, and compliant execution across WHOOP's clinical portfolio.

You will build and mentor a high-performing Clinical Operations organization. You will strengthen WHOOP's clinical operations capabilities and ensure our study execution strategy meets the expectations of regulators, investigators, participants, and the business.

QUALIFICATIONS:
  • Own the clinical operations strategy across WHOOP's portfolio of regulated and unregulated health features, including feasibility, validation, regulatory submission, launch, and post-market evidence generation.
  • Develop and execute fit-for-purpose operational models for both internally executed studies and CRO-managed validation studies, ensuring efficient evidence generation across the product lifecycle.
  • Partner with Clinical Science and cross-functional leadership to develop study execution strategies, resource plans, vendor models, and operational timelines that balance speed, quality, cost, and regulatory requirements.
  • Lead study startup, planning, execution, monitoring, and closeout activities, ensuring timelines, budgets, enrollment targets, quality objectives, and regulatory requirements are achieved.
  • Oversee participant recruitment, enrollment, retention, study logistics, and data collection activities across both internally executed and externally managed studies.
  • Lead operational oversight of CROs, technology vendors, recruitment partners, and other external service providers, establishing scalable governance frameworks, performance metrics, and escalation pathways to ensure high-quality delivery and accountability.
  • Build and oversee capabilities for internally executed studies, including decentralized clinical trials (DCTs), feasibility studies, algorithm development studies, and product research initiatives.
  • Oversee Clinical Data Management and clinical trial technologies, ensuring high-quality, timely, and compliant data collection, management, and delivery across systems including EDC, CTMS, eConsent, ePRO, eTMF, and remote study platforms.
  • Oversee study startup and regulatory operations activities, including feasibility assessments, investigator and site selection, IRB and Ethics Committee submissions, global ethics approvals, essential document management, study activation, and Trial Master File inspection readiness.
  • Ensure studies are conducted in accordance with GCP, FDA regulations, ISO 14155, company procedures, and quality requirements, while supporting audits, inspections, and regulatory submissions.
  • Build and lead a high-performing Clinical Operations organization, including hiring, mentoring, workforce planning, and establishing scalable processes, standards, and operating models.
  • Communicate study progress, operational risks, resource needs, vendor performance, and portfolio status to executive leadership and key stakeholders.
RESPONSIBILITIES:
  • Bachelor's degree required; advanced degree (MS, MPH, MBA, RN, PharmD, PhD, or equivalent) preferred.
  • 10+ years of experience in clinical operations, clinical research, medical devices, digital health, diagnostics, pharmaceuticals, or another regulated healthcare environment.
  • 5+ years of experience leading multidisciplinary clinical operations teams, including Clinical Trial Management, Clinical Monitoring, Clinical Data Management, Study Startup, and Clinical Operations functions.
  • Demonstrated experience overseeing CRO-managed clinical studies and external vendor partnerships.
  • Experience leading internally executed clinical research programs, including decentralized clinical trials, participant-facing operations, site management, direct-to-participant research, or hybrid study models.
  • Deep expertise in clinical trial execution, study startup, participant recruitment, monitoring, enrollment, clinical data management, trial master file oversight, and study closeout activities.
  • Experience managing clinical study budgets, vendor contracts, resource forecasting, and portfolio planning.
  • Strong understanding of GCP, FDA regulations, ISO 14155, IRB/Ethics Committee processes, and medical device clinical research requirements.
  • Excellent written and verbal communication skills, with the ability to translate complex operational, clinical, and regulatory concepts for diverse audiences.
This role is based in the WHOOP office located in Boston, MA. The successful candidate must be prepared to relocate if necessary to work out of the Boston, MA office. 
 
Interested in the role, but don't meet every qualification? We encourage you to still apply! At WHOOP, we believe there is much more to a candidate than what is written on paper, and we value character as much as experience. As we continue to build a diverse and inclusive environment, we encourage anyone who is interested in this role to apply.
 
WHOOP is an Equal Opportunity Employer and participates in E-verify to determine employment eligibility.  It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
 
The WHOOP compensation philosophy is designed to attract, motivate, and retain exceptional talent by offering competitive base salaries, meaningful equity, and consistent pay practices that reflect our mission and core values.
 
At WHOOP, we view total compensation as the combination of base salary, equity, and benefits, with equity serving as a key differentiator that aligns our employees with the long-term success of the company and allows every member of our corporate team to own part of WHOOP and share in the company's long-term growth and success.
 
The U.S. base salary range for this full-time position is $210,000-$230,000 Salary ranges are determined by role, level, and location. Within each range, individual pay is based on factors such as job-related skills, experience, performance, and relevant education or training. 
In addition to the base salary, the successful candidate will also receive benefits and a generous equity package.
 
These ranges may be modified in the future to reflect evolving market conditions and organizational needs. While most offers will typically fall toward the starting point of the range, total compensation will depend on the candidate's specific qualifications, expertise, and alignment with the role's requirements.
 
Learn more about WHOOP.
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About Whoop

Sourced by ZipRecruiter

At WHOOP, we're on a mission to unlock human performance. WHOOP empowers users (Olympians, Professional Athletes, Fitness Enthusiasts, etc) to perform at a higher level through a deeper understanding of their bodies and daily lives.

Industry

Fitness and sports centers

Company size

501 - 1,000 Employees

Headquarters location

Boston, MA, US

Year founded

2012

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