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$98K

$186.5K

How much do international clinical operations jobs pay per year?

As of Jun 9, 2026, the average yearly pay for international clinical operations in the United States is $98,039.00, according to ZipRecruiter salary data. Most workers in this role earn between $72,500.00 and $113,500.00 per year, depending on experience, location, and employer.

What are International Clinical Operations?

International Clinical Operations refer to the planning, management, and execution of clinical trials conducted across multiple countries. Professionals in this field ensure that clinical studies comply with global regulatory standards, coordinate with international sites, and manage logistics such as patient recruitment, data collection, and reporting. Their work is essential for bringing new medical therapies to global markets efficiently and ethically. Successful international operations require strong project management skills, cultural awareness, and knowledge of local regulations. The ultimate goal is to ensure high-quality, timely, and compliant clinical trial outcomes worldwide.

What are the key skills and qualifications needed to thrive in International Clinical Operations, and why are they important?

To thrive in International Clinical Operations, you need a solid background in clinical research, regulatory compliance, project management, and typically a relevant life sciences degree. Familiarity with clinical trial management systems (CTMS), ICH-GCP guidelines, and certifications like ACRP or SOCRA are often required. Strong organizational, cross-cultural communication, and leadership skills help foster collaboration across global teams and sites. These skills ensure the efficient, compliant, and successful execution of multinational clinical trials.

What are some common challenges faced in International Clinical Operations, and how can professionals prepare for them?

Professionals in International Clinical Operations often encounter challenges such as navigating varying regulatory requirements across countries, managing communication across different time zones, and ensuring consistent protocol adherence at global sites. To prepare, it’s important to develop strong cross-cultural communication skills, stay updated on international regulatory guidelines, and utilize robust project management tools. Building a network of reliable local partners and being adaptable to changing environments also greatly contribute to overcoming these hurdles and ensuring successful trial execution.
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International Clinical Operations jobs near you
Infographic showing various International Clinical Operations job openings in the United States as of June 2026, with employment types broken down into 72% Full Time, 19% Part Time, and 9% Contract. Highlights an 95% Physical, 2% Hybrid, and 3% Remote job distribution, with an average salary of $98,039 per year, or $47.1 per hour.
Associate Director, Clinical Operations

Associate Director, Clinical Operations

Artiva Biotherapeutics, Inc.

San Diego, CA • On-site

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 18 days ago

Job description

About Artiva:
We are a clinical-stage biotechnology company focused on developing natural killer (NK) cell-based therapies. Our mission is to develop effective, safe, and accessible cell therapies for patients with devastating autoimmune diseases. We aim to develop therapies that patients and physicians can utilize in a community setting. Our lead product candidate, AlloNK®, is a non-genetically modified, cryopreserved NK cell therapy being evaluated in combination with B-cell targeted monoclonal antibodies (mAbs). We believe the compelling cell killing properties of NK cells, when combined with mAbs for targeting, creates an opportunity to generate potentially transformative therapies.
For more information, visit www.artivabio.com.
Job Summary:
The Associate Director, Clinical Operations will manage clinical trials as part of the clinical operations team. They will be involved in the daily operations of Artiva's clinical programs through vendors. This person may lead a small team of clinical operations professionals and will be expected to provide vision, leadership, and mentoring to their assigned team.
The role requires an excellent understanding of Autoimmune and Cell Therapy trials. They must have strong problem solving and communication skills and be able to deal with evolving and complex business problems. They need to be able to bring recommendations to management and support strategic analysis affecting programs and priorities. They must facilitate effective internal and external relationships, and they are responsible for the achievement of project goals.
Duties/Responsibilities:
  • Manage complex Phase 1, 2, 3, and 4 clinical trials as part of the Artiva Clinical Operations team.
  • Demonstrate oversight of CROs and work in a quality framework that supports early and confirmatory trials
  • Provide direction and leadership in CRO and vendor selection and management.
  • Knowledge of regulatory start up process and planning in support of study start up
  • Building, managing, and maintaining high performing clinical teams
  • Contribute to strategic planning to ensure optimized clinical development plans for assigned projects. Inclusive of this is enrollment modelling to support scenario planning for portfolio optimization and spend/timeline analysis.
  • Provide technical expertise for the development of clinical documents (protocols, monitoring plans, clinical trials report, investigator brochures, etc.) and trial conduct.
  • Coordinate closely with Clinical Development, Biostatistics, Data Management, Drug Safety, Legal, Finance, Project Management and Regulatory to ensure operational excellence.
  • Be responsible for, and manage, clinical research activity of Clinical Trial Managers and other staff.
  • Prepare clinical research budgets and timelines. Manage trial budgets, spend analysis and accuracy in partnership with management and Artiva finance teams.
  • Analyze and develop action plans to address issues with investigational sites, CRAs, and CROs
  • Work with departmental leadership and Quality to identify and improve Artiva SOPs.
  • Responsible for preparing Requests for Proposals documents (RFP's) and soliciting bids from CROs and vendors, evaluating the submitted proposals for merit and fit, and developing a rationale for selecting a preferred vendor with the Clinical Operations Team.
  • Accountable for the management of vendor agreements for outsourced activities, including vendors' adherence to the scope of service agreements, budgets, plans and timelines, ensuring that change orders to the work scope and budgets meet clinical operations specifications.
  • Responsible for driving a feasibility process leading to a collaborative evaluation and selection of clinical trial sites.
  • Responsible for driving enrollment efforts to deliver the program.

Requirements:
  • Bachelor's degree in a life science related field or equivalent work experience strongly preferred. An advanced degree in a life science discipline is strongly preferred.
  • Experience in Cell Therapy, Autoimmune or Rare Disease is strongly preferred
  • A minimum of 10 years' relevant industry experience, including CRO/vendor management, with expertise in clinical operations leading early through late-stage clinical trials
  • Expertise in the areas of drug development, operations, and strategic planning, specifically management of clinical trial operations.
  • Demonstrated experience managing and mentoring clinical team members, in a matrix environment.
  • Demonstrated knowledge of international clinical pharmaceutical standards, ICH/GCP guidelines, and regulatory compliance.
  • Must have extensive experience managing CROs, central laboratories, and other clinical study vendors.
  • Must have a working knowledge of data management, data review and analysis, and drug safety and pharmacovigilance.
  • Ability to work on and solve complex problems.
  • Ability to prioritize and handle multiple tasks simultaneously.
  • Effective leadership skills and proven ability to foster team productivity and cohesiveness.
  • Excellent communication/interaction skills and experience in a dynamic and growing organization.

Ability to travel, up to 25%, includes the possibility of international travel.
In addition to a great culture, we offer:
  • A beautiful facility
  • An entrepreneurial, highly collaborative, and innovative environment
  • Comprehensive benefits, including:
  • Medical, Dental, and Vision
  • Group Life Insurance
  • Long Term Disability (LTD)
  • 401(k) Retirement Plan
  • Employee Assistance Program (EAP)
  • Flexible Spending Account (FSA)
  • Paid Time Off (PTO)
  • Company paid holidays, including the year-end holiday week
  • Our recognition program, Bonus.ly, is where you can trade in points earned for things you want.

If all this speaks to you, come join us on our journey!
Base Salary: $190,000 - $200,000. Exact compensation may vary based on level, skills and experience

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