A B2B appointment setter is a telephone sales representative responsible for coordinating appointments between new business clients and the sales team of a business. Your job duties include contacting potential clients, using social sales technologies, and coordinating appointments among multiple team members. A career as a B2B appointment setter does not require you have postsecondary education or formal qualifications, though prior experience in sales will set you ahead of other candidates during your job search. To excel in this position, you should possess excellent communication skills along with strong interpersonal skills.