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Clinical Operations Jobs (NOW HIRING)

Insperity

Clinical Operations Manager

Phoenix, AZ

Description & Requirements Clinical Operations Manager A leading healthcare organization specializing in renal care and outpatient surgical services is seeking an experienced Clinical Operations ...

Wake Research

Clinical Operations Lead

Raleigh, NC · Remote

The Clinical Operations Lead is responsible for driving the successful execution of clinical trials across multiple sites and priority programs. This role ensures studies meet enrollment targets ...

Karoo Health

Director, Clinical Operations

Denver, CO · On-site +1

The Role The Director of Clinical Operations will lead the development, refinement, and execution of Karoo's clinical care model. This leader will translate clinical strategy into scalable workflows ...

M3USA

Clinical Operations Lead

Raleigh, NC · Remote

The Clinical Operations Lead is responsible for driving the successful execution of clinical trials across multiple sites and priority programs. This role ensures studies meet enrollment targets ...

M3USA

Clinical Operations Lead

Raleigh, NC · Remote

The Clinical Operations Lead is responsible for driving the successful execution of clinical trials across multiple sites and priority programs. This role ensures studies meet enrollment targets ...

M3USA

Clinical Operations Lead

Raleigh, NC · On-site +1

The Clinical Operations Lead is responsible for driving the successful execution of clinical trials across multiple sites and priority programs. This role ensures studies meet enrollment targets ...

Grand Mental Health

Clinical Operations Manager

Tulsa, OK · On-site

$60K - $70K/yr

Description The Clinical Operations Manager is responsible for the administrative and day to day operational oversight of ARC clinical programming and multidisciplinary clinical support functions.

Tr1X

Director, Clinical Operations

San Diego, CA · On-site

Position Summary The Director, Clinical Operations provides strategic leadership and operational oversight for the implementation and execution of clinical trials from study start-up through close ...

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Clinical Operations information

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$35K

$98K

$186.5K

How much do clinical operations jobs pay per year?

As of Jun 13, 2026, the average yearly pay for clinical operations in the United States is $98,039.00, according to ZipRecruiter salary data. Most workers in this role earn between $72,500.00 and $113,500.00 per year, depending on experience, location, and employer.

How does a Clinical Operations professional typically collaborate with cross-functional teams during a clinical trial?

Clinical Operations professionals play a central role in coordinating activities among various teams such as regulatory affairs, data management, biostatistics, and clinical research associates. They ensure that timelines are met, protocols are followed, and all departments are aligned with trial objectives. Regular meetings, clear communication, and the ability to anticipate and resolve operational challenges are essential to successful collaboration. This cross-functional teamwork helps maintain trial quality and regulatory compliance throughout the study.

What is the role of clinical operations?

Clinical operations professionals oversee the planning, execution, and management of clinical trials to ensure they are conducted efficiently, ethically, and in compliance with regulatory standards. They coordinate activities such as site selection, patient recruitment, data management, and monitoring, often using specialized tools and requiring knowledge of Good Clinical Practice (GCP) guidelines.

What jobs pay 2000 a day?

In clinical operations, high-paying roles such as senior clinical consultants, project directors, or specialized medical advisors can earn around $2,000 per day, especially with extensive experience, certifications, and in high-demand environments. These positions often require advanced degrees, strong project management skills, and a track record of successful clinical trial oversight.

What is clinical operations?

Clinical operations refers to the planning, management, and execution of clinical trials and research studies within the healthcare and pharmaceutical industries. Professionals in clinical operations ensure that studies are conducted efficiently, ethically, and in compliance with regulatory requirements. Their responsibilities may include site management, patient recruitment, data collection, and ensuring protocol adherence. The goal is to facilitate the safe and effective development of new medical treatments and therapies.

What is the difference between Clinical Operations vs Clinical Research Associate?

AspectClinical OperationsClinical Research Associate
Required CredentialsBachelor's degree, experience in clinical trial managementBachelor's degree, often with certification in clinical research
Work EnvironmentProject management, coordinating multiple trial sitesMonitoring clinical sites, ensuring protocol compliance
Employer & Industry UsagePharmaceutical companies, CROs, biotech firmsResearch sites, CROs, pharmaceutical companies
Common Search & ComparisonFocuses on trial oversight and managementFocuses on site monitoring and data verification

Clinical Operations professionals oversee the planning, coordination, and management of clinical trials, ensuring they run smoothly across multiple sites. Clinical Research Associates primarily monitor clinical trial sites, verify data accuracy, and ensure compliance with protocols. While both roles require knowledge of clinical research, Clinical Operations has a broader scope involving project management, whereas CRAs focus on site-level monitoring.

Is CRA an entry level job?

A Clinical Research Associate (CRA) is typically not an entry-level position; it usually requires prior experience in clinical research, healthcare, or related fields. Entry-level roles in clinical operations may include clinical trial assistants or coordinators, with CRAs often needing a bachelor's degree and relevant certifications such as ACRP or SOCRA credentials. Advancement to CRA roles generally involves gaining experience and developing skills in monitoring, regulatory compliance, and data management.

What are the key skills and qualifications needed to thrive in Clinical Operations, and why are they important?

To thrive in Clinical Operations, you need expertise in clinical trial management, regulatory compliance, and data analysis, typically supported by a degree in life sciences or a related field. Familiarity with clinical trial management systems (CTMS), Good Clinical Practice (GCP) certification, and electronic data capture (EDC) platforms is essential. Strong leadership, problem-solving, and communication skills help coordinate teams and ensure project timelines are met. These skills are crucial for guaranteeing efficient, compliant, and successful clinical trial execution in a highly regulated environment.

What job makes $10,000 a month without a degree?

In clinical operations, roles such as senior project managers or clinical consultants can earn around $10,000 per month with extensive experience and industry knowledge, often requiring strong organizational skills and certifications like PMP. However, most high-paying clinical roles typically require relevant education or specialized training, and salaries vary based on location and employer.
More about Clinical Operations jobs
What cities are hiring for Clinical Operations jobs? Cities with the most Clinical Operations job openings:
What are the most commonly searched types of Clinical Operations jobs? The most popular types of Clinical Operations jobs are:
What states have the most Clinical Operations jobs? States with the most job openings for Clinical Operations jobs include:
What job categories do people searching Clinical Operations jobs look for? The top searched job categories for Clinical Operations jobs are:
Clinical Operations jobs near you
Infographic showing various Clinical Operations job openings in the United States as of June 2026, with employment types broken down into 4% As Needed, 69% Full Time, 18% Part Time, and 9% Contract. Highlights an 95% Physical, 2% Hybrid, and 3% Remote job distribution, with an average salary of $98,039 per year, or $47.1 per hour.
Director, Clinical Operations

Director, Clinical Operations

Septerna

South San Francisco, CA

$225K - $250K/yr

Other

Posted 28 days ago

Job description

THE ROLE

The Director, Clinical Operations will lead the strategic planning, execution, and continuous improvement of Septerna's clinical programs across multiple therapeutic areas. This role is pivotal in a dynamic, fast-growing biotech environment and will ensure our clinical trials are delivered with excellence-on time, within budget, and in compliance with regulatory and quality standards.

This is an exciting opportunity with significant room for growth and visibility across the organization. The Director will work closely with senior leadership and cross-functional teams, gaining exposure to all levels of the company while helping to shape the future of Septerna's clinical operations. The ideal candidate combines deep operational expertise with a patient-first mindset, thrives in collaboration, and brings creativity and structure to a scaling organization.

Key Responsibilities

  • Lead operational planning and execution of clinical programs (Phase I-III, including patient-facing , global studies) in alignment with development goals.
  • Oversee end-to-end delivery of clinical trials: define timelines, budgets, risk mitigation, resource allocation, and monitoring of results.
  • Select, contract, and manage CROs and external vendors; build strong vendor relationships, ensure accountability to scope, budget, milestones, and quality.
  • Collaborate across functions - Clinical Development, Regulatory, Biometrics/Data, QA,  - to ensure aligned execution and streamlined decision-making.
  • Build and mentor a growing clinical operations team; drive team development, foster a culture of learning, accountability, innovation, and high performance.
  • Drive operational excellence by creating and implementing fit-for-purpose processes, systems and tools that support a scaling organization - standardizing templates, SOPs, dashboards, KPIs.
  • Demonstrate ability to quickly adopt new therapeutic areas, adapt to evolving science and growing strategic demands.
  • Bring creative, out-of-the-box thinking to optimize trial design, site operations, patient engagement, vendor strategies and operational efficiency.
  • Ensure inspection readiness and adherence to ICH-GCP, SOPs and global regulatory standards; partner with QA to maintain operational integrity.
  • Establish and track meaningful metrics (KPIs) to manage progress, proactively manage risks, and drive continuous improvement in trial efficiency and data quality.

Qualifications

  • Advanced degree (MS, PharmD, PhD) preferred; or bachelor's degree in life sciences/clinical research with equivalent robust experience.
  • Minimum 10  years' experience in clinical operations in biotech or pharma, with leadership of multiple global clinical programs (including patient-facing studies).
  • Demonstrated success in building and mentoring teams; experience in a growing/scaling environment is highly desirable.
  • Proven track record managing CROs/external vendors, budgets/timelines, and operational delivery in a complex setting.
  • Effective cross-functional collaborator; strong communicator able to navigate a matrixed, fast-moving organization.
  • Experience in or ability to quickly learn new therapeutic areas (endorcrinology, immunology/inflammation, metabolic disease or similar) is strongly preferred.
  • Demonstrated process-orientation: able to build, refine and standardize systems, tools, SOPs, dashboards and metrics.
  • Strategic thinker with proactive, solution-driven mindset; able to bring innovative thinking to trial operations.
  • Results-oriented, detail conscious, and adept at managing multiple priorities under deadlines.

The anticipated salary range for candidates who will work in South San Francisco, CA is $225,000 - $250,000. Individual pay may vary based on additional factors, including, and without limitation, job-related skills, experience, work location and relevant education or training. Septerna's compensation package also includes benefits, stock options, and annual target bonus for full-time positions.

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