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Clinical Operations Jobs in Boston, MA (NOW HIRING)

Clinovo

Dir, Clinical Operations

Cambridge, MA · On-site

The successful candidate will lead clinical operations for an autoimmune and immunology-focused development portfolio, with a particular emphasis on early-phase and operationally complex studies.

Whoop

Director, Clinical Operations

Boston, MA · On-site

As the Director, Clinical Operations, you will lead the clinical operations function responsible for executing the studies that support WHOOP's regulated and unregulated health features, with a ...

Doist

Director, Clinical Operations

Boston, MA · On-site

$215 - $240/hr

Role Overview The Director, Clinical Operations will oversee the strategic and operational execution of clinical trials, leading cross-functional teams and collaborating with internal stakeholders ...

inno

Clinical Operations Specialist

Middleton, MA · On-site

The Clinical Operations Specialist I (COS I) is responsible for managing all clinical operations reporting related to timely documentation and compliance. The COS I also manages all office and ...

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Clinical Operations information

See Boston, MA salary details

$38K

$106.5K

$202.6K

How much do clinical operations jobs pay per year?

As of Aug 9, 2026, the average yearly pay for clinical operations in Boston, MA is $106,508.00, according to ZipRecruiter salary data. Most workers in this role earn between $78,800.00 and $123,300.00 per year, depending on experience, location, and employer.

How does a clinical operations professional typically collaborate with cross-functional teams during a clinical trial?

Clinical Operations professionals play a central role in coordinating activities among various teams such as regulatory affairs, data management, biostatistics, and clinical research associates. They ensure that timelines are met, protocols are followed, and all departments are aligned with trial objectives. Regular meetings, clear communication, and the ability to anticipate and resolve operational challenges are essential to successful collaboration. This cross-functional teamwork helps maintain trial quality and regulatory compliance throughout the study.

What is clinical operations?

Clinical operations refers to the planning, management, and execution of clinical trials and research studies within the healthcare and pharmaceutical industries. Professionals in clinical operations ensure that studies are conducted efficiently, ethically, and in compliance with regulatory requirements. Their responsibilities may include site management, patient recruitment, data collection, and ensuring protocol adherence. The goal is to facilitate the safe and effective development of new medical treatments and therapies.

What is the difference between Clinical Operations vs Clinical Research Associate?

AspectClinical OperationsClinical Research Associate
Required CredentialsBachelor's degree, experience in clinical trial managementBachelor's degree, often with certification in clinical research
Work EnvironmentProject management, coordinating multiple trial sitesMonitoring clinical sites, ensuring protocol compliance
Employer & Industry UsagePharmaceutical companies, CROs, biotech firmsResearch sites, CROs, pharmaceutical companies
Common Search & ComparisonFocuses on trial oversight and managementFocuses on site monitoring and data verification

Clinical Operations professionals oversee the planning, coordination, and management of clinical trials, ensuring they run smoothly across multiple sites. Clinical Research Associates primarily monitor clinical trial sites, verify data accuracy, and ensure compliance with protocols. While both roles require knowledge of clinical research, Clinical Operations has a broader scope involving project management, whereas CRAs focus on site-level monitoring.

What are the key skills and qualifications needed to thrive in clinical operations, and why are they important?

To thrive in Clinical Operations, you need expertise in clinical trial management, regulatory compliance, and data analysis, typically supported by a degree in life sciences or a related field. Familiarity with clinical trial management systems (CTMS), Good Clinical Practice (GCP) certification, and electronic data capture (EDC) platforms is essential. Strong leadership, problem-solving, and communication skills help coordinate teams and ensure project timelines are met. These skills are crucial for guaranteeing efficient, compliant, and successful clinical trial execution in a highly regulated environment.
What are the most commonly searched types of Clinical Operations jobs in Boston, MA? The most popular types of Clinical Operations jobs in Boston, MA are:
What job categories do people searching Clinical Operations jobs in Boston, MA look for? The top searched job categories for Clinical Operations jobs in Boston, MA are:
What cities near Boston, MA are hiring for Clinical Operations jobs? Cities near Boston, MA with the most Clinical Operations job openings:
Clinical Operations jobs near you
Infographic showing various Clinical Operations job openings in Boston, MA as of August 2026, with employment types broken down into 83% Full Time, 13% Part Time, 1% Temporary, and 3% Contract. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $106,508 per year, or $51.2 per hour.

Associate Director, Clinical Operations

Clinical Dynamix, Inc.

Watertown, MA • On-site

Full-time

Re-posted 28 days ago

Job description

Associate Director, Clinical Operations Job Description

How you’ll make an impact:

  • Contribute to the planning, implementation, and execution of global clinical trials.
  • Plan, execute, and lead study-specific meetings (e.g., internal core team meetings, investigator meetings, etc), as needed.
  • Provide input for the design of the Informed Consent Form(s), eCRFs, monitoring conventions, edit checks, etc.
  • Provide study-specific training and leadership to clinical research staff, CRO, CRAs, sites and other contract personnel.
  • Manage study timelines and metrics to ensure completion of study deliverables.
  • Lead site feasibility and selection qualification, initiation, and oversight of outsourced monitoring activities.
  • Review monitoring reports to ensure quality and resolution of site-related issues.
  • Ensure timely enrollment and data collection at clinical trial sites.
  • Collaborate with the data management team to ensure data integrity and timely database lock.
  • Ensure tracking, review of protocol deviations, and assess impact on study data.
  • Work closely with translational medicine team to ensure appropriate incorporation of bioanalytical sampling plan into clinical protocols and relevant data output of the trial is provided to functional groups for review.
  • Partner with Operational Excellence and assigned Site Engagement Leads to help drive site engagement and bolster recruitment
  • Serve as key counterpart of Clinical Outsourcing to build RFPs and support the selection of clinical vendors
  • Oversee and contribute to Sponsor Oversight activities including but not limited to review of KPIs, KRIs, PDs, risks, Data Review Findings, etc. to assess the health of the study and proactively ensure mitigations are in place to achieve Company’s quality standards
  • Contribute to clinical operations process improvement initiatives
  • Maintain accurate and complete trial documentation.
  • Proactively identify and resolve clinical project issues.
  • This role may require up to 25% travel

Skills and experience you’ll bring:

  • BS degree and 8+ years of experience in clinical operations in biotech/pharma. 5 years’ experience leading global clinical trials
  • Inspection readiness experience preferred
  • Experience working on large, global, complex phase 2b/3 or late stage trials. Respiratory or Immunology experience highly preferred.
  • Broad knowledge of Global regulations and guidelines including CFR, ICH GCP, HIPAA, GDPR, and the Protection of Human Research Subjects.
  • Strong project management skills with the ability to manage multiple trials simultaneously.
  • Excellent problem-solving, leadership, and communication skills.
  • Ability to work in a fast-paced, dynamic environment with cross-functional teams.