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Clinical Operations Jobs in Boston, MA (NOW HIRING)

Clinovo

Dir, Clinical Operations

Cambridge, MA · On-site

The successful candidate will lead clinical operations for an autoimmune and immunology-focused development portfolio, with a particular emphasis on early-phase and operationally complex studies.

Whoop

Director, Clinical Operations

Boston, MA · On-site

As the Director, Clinical Operations, you will lead the clinical operations function responsible for executing the studies that support WHOOP's regulated and unregulated health features, with a ...

Doist

Director, Clinical Operations

Boston, MA · On-site

$215 - $240/hr

Role Overview The Director, Clinical Operations will oversee the strategic and operational execution of clinical trials, leading cross-functional teams and collaborating with internal stakeholders ...

inno

Clinical Operations Specialist

Middleton, MA · On-site

The Clinical Operations Specialist I (COS I) is responsible for managing all clinical operations reporting related to timely documentation and compliance. The COS I also manages all office and ...

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Clinical Operations information

See Boston, MA salary details

$38K

$106.5K

$202.6K

How much do clinical operations jobs pay per year?

As of Aug 15, 2026, the average yearly pay for clinical operations in Boston, MA is $106,504.00, according to ZipRecruiter salary data. Most workers in this role earn between $78,800.00 and $123,300.00 per year, depending on experience, location, and employer.

How does a clinical operations professional typically collaborate with cross-functional teams during a clinical trial?

Clinical Operations professionals play a central role in coordinating activities among various teams such as regulatory affairs, data management, biostatistics, and clinical research associates. They ensure that timelines are met, protocols are followed, and all departments are aligned with trial objectives. Regular meetings, clear communication, and the ability to anticipate and resolve operational challenges are essential to successful collaboration. This cross-functional teamwork helps maintain trial quality and regulatory compliance throughout the study.

What is clinical operations?

Clinical operations refers to the planning, management, and execution of clinical trials and research studies within the healthcare and pharmaceutical industries. Professionals in clinical operations ensure that studies are conducted efficiently, ethically, and in compliance with regulatory requirements. Their responsibilities may include site management, patient recruitment, data collection, and ensuring protocol adherence. The goal is to facilitate the safe and effective development of new medical treatments and therapies.

What is the difference between Clinical Operations vs Clinical Research Associate?

AspectClinical OperationsClinical Research Associate
Required CredentialsBachelor's degree, experience in clinical trial managementBachelor's degree, often with certification in clinical research
Work EnvironmentProject management, coordinating multiple trial sitesMonitoring clinical sites, ensuring protocol compliance
Employer & Industry UsagePharmaceutical companies, CROs, biotech firmsResearch sites, CROs, pharmaceutical companies
Common Search & ComparisonFocuses on trial oversight and managementFocuses on site monitoring and data verification

Clinical Operations professionals oversee the planning, coordination, and management of clinical trials, ensuring they run smoothly across multiple sites. Clinical Research Associates primarily monitor clinical trial sites, verify data accuracy, and ensure compliance with protocols. While both roles require knowledge of clinical research, Clinical Operations has a broader scope involving project management, whereas CRAs focus on site-level monitoring.

What are the key skills and qualifications needed to thrive in clinical operations, and why are they important?

To thrive in Clinical Operations, you need expertise in clinical trial management, regulatory compliance, and data analysis, typically supported by a degree in life sciences or a related field. Familiarity with clinical trial management systems (CTMS), Good Clinical Practice (GCP) certification, and electronic data capture (EDC) platforms is essential. Strong leadership, problem-solving, and communication skills help coordinate teams and ensure project timelines are met. These skills are crucial for guaranteeing efficient, compliant, and successful clinical trial execution in a highly regulated environment.

What are the most commonly searched types of Clinical Operations jobs in Boston, MA?

The most popular types of Clinical Operations jobs in Boston, MA are:

What are popular job titles related to Clinical Operations jobs in Boston, MA?

For Clinical Operations jobs in Boston, MA, the most frequently searched job titles are:

What job categories do people searching Clinical Operations jobs in Boston, MA look for?

The top searched job categories for Clinical Operations jobs in Boston, MA are:

What cities near Boston, MA are hiring for Clinical Operations jobs?

Cities near Boston, MA with the most Clinical Operations job openings:

Clinical Operations jobs near you
Infographic showing various Clinical Operations job openings in Boston, MA as of August 2026, with employment types broken down into 84% Full Time, 12% Part Time, 1% Temporary, and 3% Contract. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $106,504 per year, or $51.2 per hour.

Dir, Clinical Operations

Clinovo

Cambridge, MA • On-site

Other

Medical, Dental, Vision, Retirement, PTO

Re-posted 22 days ago

Job description

Position Overview
A growth-stage biotechnology company focused on innovative therapeutic development is seeking a highly motivated and detail-oriented Clinical Operations leader who thrives in lean, fast-moving environments and is energized by the opportunity to help build infrastructure, teams (direct and/or external relationships), and operational strategy around novel science.
The successful candidate will lead clinical operations for an autoimmune and immunology-focused development portfolio, with a particular emphasis on early-phase and operationally complex studies. Working closely with Clinical Development and broader cross-functional teams, this individual will drive operational strategy, study execution, and CRO/vendor oversight as programs launch across APAC and subsequently expand into the United States and Europe.
This role requires a leader who operates both strategically and tactically-developing scalable operational frameworks while remaining close enough to execution to resolve issues in real time.
The individual will serve as a key operational leader and cross-functional connector, partnering closely with Clinical Development, Clinical Operations, Translational Science, Medical Affairs, Regulatory Affairs, Biometrics, and Quality to ensure aligned and efficient global trial execution.
This opportunity is best suited for a sponsor-side clinical operations leader who takes strong ownership of study strategy, execution, and CRO accountability while fostering collaborative, high-performing partnerships with external vendors and service providers.
Key Responsibilities
  • Drive clinical operations strategy and execution for an autoimmune/immunology-focused clinical portfolio, beginning within APAC and expanding into the United States and Europe
  • Provide operational leadership across all stages of study execution, including feasibility, site selection, study start-up, enrollment strategy, monitoring oversight, vendor management, data quality, and study closeout
  • Build and maintain strategic relationships with investigators, institutions, early-phase units, and clinical trial networks across APAC, and establish equivalent partnerships as programs expand globally
  • Drive operational excellence and accountability across CROs, vendors, and study partners through proactive governance frameworks, performance metrics, and escalation processes
  • Oversee study timelines, budgets, enrollment forecasting, resource planning, and operational risk management to support delivery against program milestones
  • Partner cross-functionally with Clinical Development, Translational Science, Medical Affairs, Regulatory Affairs, Biometrics, and Quality to align scientific and operational priorities
  • Provide strategic oversight of site engagement and enrollment initiatives, particularly in immunology, autoimmune disease, and advanced therapeutic clinical settings
  • Ensure inspection readiness and compliance with ICH-GCP, regional and global regulatory requirements, and applicable clinical trial standards across multiple jurisdictions
  • Support development and scaling of internal clinical operations infrastructure, SOPs, processes, and operational best practices appropriate for a growing biotechnology organization
  • Directly manage, mentor, and develop clinical operations personnel while supporting growth and expansion of the broader clinical operations function across regions
  • Foster a collaborative, accountable, and execution-focused team culture
  • Contribute to strategic planning for future clinical programs, including operational scalability across additional indications and geographies
Required Qualifications
  • Bachelor's degree in life sciences, health sciences, or a related discipline; advanced degree preferred
  • 10+ years of progressive clinical operations experience within sponsor biotechnology and/or pharmaceutical organizations
  • Demonstrated experience within sponsor organizations where ownership of study strategy, vendor oversight, timelines, budgets, and overall trial execution accountability were core responsibilities
  • Significant experience leading global and/or multi-regional clinical trials, including early-phase (Phase I/II) studies, with demonstrated success operating across multiple regulatory jurisdictions
  • Strong operational leadership experience in immunology, autoimmune disease, cell therapy, gene therapy, or other advanced therapeutic modalities
  • Demonstrated sponsor-side experience overseeing CROs and external vendors, including governance, performance management, escalation management, and operational accountability
  • Strong understanding of APAC clinical trial regulations and operational frameworks, with working knowledge of-or demonstrated ability to support-US and European clinical trial requirements and global regulatory standards
  • Proven ability to build strategic relationships with investigators, institutions, and site networks across global regions
  • Experience operating successfully within lean or emerging biotech environments where flexibility, autonomy, and hands-on leadership are essential
  • Excellent leadership, communication, and stakeholder management skills with the ability to influence across organizational levels
  • Ability to travel domestically and internationally as required
Preferred Qualifications
  • Prior experience supporting cell therapy, CAR-T, gene therapy, mRNA, or other advanced therapy medicinal product (ATMP) studies
  • Experience supporting autoimmune disease or immunology clinical programs
  • Established relationships with investigative sites, clinical networks, and key opinion leaders within APAC and/or globally
  • Experience building or scaling clinical operations infrastructure within an emerging biotechnology company
  • Familiarity with translational-heavy or biomarker-driven clinical trial designs
  • Experience supporting global inspections or regulatory authority interactions
Benefits May Include
  • Equity participation and long-term incentive opportunities
  • Comprehensive medical, dental, and vision coverage for employees and eligible dependents
  • Retirement savings program with company contribution or matching opportunities
  • Generous paid time off, company holidays, and sick leave
  • Paid parental leave and family support benefits
  • Flexible or hybrid work arrangements to support work-life balance
  • Transportation and commuter assistance programs, where applicable

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