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Clinical Operations Jobs in Missouri (NOW HIRING)

Techlink Systems

Be Seen First

HIRING! Clinical Operations Coordinator - JD25

Kansas City, MO · On-site

$25.50 - $27.65/hr

Preferred Qualifications * 0-1 years of experience in customer support, healthcare operations, clinical program knowledge, data entry, or administrative roles. * Familiarity with CRM systems ...

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Mercy

Executive Director Clinical Innovation

Chesterfield, MO · On-site

$79K - $107K/yr

The ideal candidate will bring deep expertise in clinical operations, informatics, and emerging technologies such as artificial intelligence (AI), with a proven ability to lead change in complex ...

QPS

Clinical Pharmacist

Springfield, MO · On-site

$107K - $128K/yr

Clinical Pharmacist Since its inception, QPS has been assisting pharmaceutical, biotechnology and ... Underpinning the operation is a culture that values diversity, innovation and accountability.

Mercy

Executive Director Clinical Innovation

Chesterfield, MO · On-site

$79K - $107K/yr

The ideal candidate will bring deep expertise in clinical operations, informatics, and emerging technologies such as artificial intelligence (AI), with a proven ability to lead change in complex ...

Mercy

Executive Director Clinical Innovation

Chesterfield, MO · On-site

$79K - $107K/yr

The ideal candidate will bring deep expertise in clinical operations, informatics, and emerging technologies such as artificial intelligence (AI), with a proven ability to lead change in complex ...

Mercy

Executive Director Clinical Innovation

Chesterfield, MO · On-site

$79K - $107K/yr

The ideal candidate will bring deep expertise in clinical operations, informatics, and emerging technologies such as artificial intelligence (AI), with a proven ability to lead change in complex ...

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All JobsClinical Operations JobsClinical Operations Jobs in Missouri

Clinical Operations information

See Missouri salary details

$32.8K

$92K

$174.9K

How much do clinical operations jobs pay per year?

As of Aug 2, 2026, the average yearly pay for clinical operations in Missouri is $91,961.00, according to ZipRecruiter salary data. Most workers in this role earn between $68,000.00 and $106,500.00 per year, depending on experience, location, and employer.

How does a Clinical Operations professional typically collaborate with cross-functional teams during a clinical trial?

Clinical Operations professionals play a central role in coordinating activities among various teams such as regulatory affairs, data management, biostatistics, and clinical research associates. They ensure that timelines are met, protocols are followed, and all departments are aligned with trial objectives. Regular meetings, clear communication, and the ability to anticipate and resolve operational challenges are essential to successful collaboration. This cross-functional teamwork helps maintain trial quality and regulatory compliance throughout the study.

What is clinical operations?

Clinical operations refers to the planning, management, and execution of clinical trials and research studies within the healthcare and pharmaceutical industries. Professionals in clinical operations ensure that studies are conducted efficiently, ethically, and in compliance with regulatory requirements. Their responsibilities may include site management, patient recruitment, data collection, and ensuring protocol adherence. The goal is to facilitate the safe and effective development of new medical treatments and therapies.

What is the difference between Clinical Operations vs Clinical Research Associate?

AspectClinical OperationsClinical Research Associate
Required CredentialsBachelor's degree, experience in clinical trial managementBachelor's degree, often with certification in clinical research
Work EnvironmentProject management, coordinating multiple trial sitesMonitoring clinical sites, ensuring protocol compliance
Employer & Industry UsagePharmaceutical companies, CROs, biotech firmsResearch sites, CROs, pharmaceutical companies
Common Search & ComparisonFocuses on trial oversight and managementFocuses on site monitoring and data verification

Clinical Operations professionals oversee the planning, coordination, and management of clinical trials, ensuring they run smoothly across multiple sites. Clinical Research Associates primarily monitor clinical trial sites, verify data accuracy, and ensure compliance with protocols. While both roles require knowledge of clinical research, Clinical Operations has a broader scope involving project management, whereas CRAs focus on site-level monitoring.

What are the key skills and qualifications needed to thrive in Clinical Operations, and why are they important?

To thrive in Clinical Operations, you need expertise in clinical trial management, regulatory compliance, and data analysis, typically supported by a degree in life sciences or a related field. Familiarity with clinical trial management systems (CTMS), Good Clinical Practice (GCP) certification, and electronic data capture (EDC) platforms is essential. Strong leadership, problem-solving, and communication skills help coordinate teams and ensure project timelines are met. These skills are crucial for guaranteeing efficient, compliant, and successful clinical trial execution in a highly regulated environment.
What are the most commonly searched types of Clinical Operations jobs in Missouri? The most popular types of Clinical Operations jobs in Missouri are:
What are popular job titles related to Clinical Operations jobs in Missouri? For Clinical Operations jobs in Missouri, the most frequently searched job titles are:
What job categories do people searching Clinical Operations jobs in Missouri look for? The top searched job categories for Clinical Operations jobs in Missouri are:
What cities in Missouri are hiring for Clinical Operations jobs? Cities in Missouri with the most Clinical Operations job openings:
Clinical Operations jobs near you
Infographic showing various Clinical Operations job openings in Missouri as of July 2026, with employment types broken down into 82% Full Time, 9% Part Time, and 9% Contract. Highlights an 91% In-person, and 9% Hybrid job distribution, with an average salary of $91,961 per year, or $44.2 per hour.

Director of Clinical Operations

Jefferson City Medical Group

Jefferson City, MO • On-site

$120K - $130K/yr

Full-time

Medical, Retirement, PTO

Posted 26 days ago

Jefferson City Medical Group rating

7.9

Company rating: 7.9 out of 10

Based on 7 frontline employees who took The Breakroom Quiz

Job description

Position posted: 7/6/2026
The Director of Clinical Operations is responsible for the oversight of all operations and staff within various clinics and/or ancillary services with a specific focus on process improvement, personnel management, cost containment, and revenue enhancement. This position is instrumental in the development of clinic management. In addition, it is instrumental in the implementation of systems and programs that maintain and improve current operations and embrace opportunities for change that are present in a growing business.
RESPONSIBILITIES
Job Specific Competencies:
General
  • In collaboration with JCMG leadership, develop, implement, and monitor annual goals and objectives to meet the strategic and financial objectives of JCMG.
  • Develop and maintain relationships with key stakeholders (Board of Directors Physicians, Executive Staff, Management, and front-line staff).
  • Work with JCMG leadership to develop, review and approve the operating plans and budgets, with a keen interest in implementing internal "best practices," operational processes and targeted business growth initiatives.
  • Work in conjunction with JCMG leadership to ensure that the broad strategic vision of JCMG is implemented and communicated accurately and effectively to clinical and ancillary staff.
  • Develop and oversee the execution of "best in class" operations, logistics, services, and solutions.
  • Follows all JCMG established policies and practices.
  • Execute strategies, tactics and actions aimed at achieving JCMG's goals and objectives for revenue growth, profit, as well as employee and patient satisfaction.

Financial and Business Management and Oversight
  • Seeks and directs activities that positively impact costs of operations.
  • Seeks and achieves industry norms for supply and labor expense management.
  • Creates and complies with operational and capital budget.
  • Understands financial statements and negative variances to budget and works to resolve any variables.
  • Performs cost/benefit analysis for equipment, services, procedures, and business development.
  • Maintains a productivity system for evaluating activity within assigned clinics.
  • Makes decisions in a timely manner.
  • Takes initiative and responsibility when decision-making, problem solving, managing projects, and running meetings.

Human Resource and Performance Management
  • Oversees clinic management and collaborates directly with physician directors within assigned clinics.
  • Develops and trains management staff on systems and activities for recruitment, interviewing, hiring, retaining, orienting, and counseling employees.
  • Evaluates appropriate staff ratios and skill set requirements to maximize human resource effectiveness.
  • Achieves established productivity standards.
  • Completes established payroll functions.
  • Delegates routine and critical tasks/responsibilities appropriately.
  • Empowers others with the resources and authority needed to succeed.
  • Takes timely corrective action for inferior performance.
  • Recognizes and rewards people for excellent performance.
  • Follows all JCMG employee policies.

Clinical and Business Operations' Management
  • Provides oversight and direction for both clinical and business operations of assigned clinics.
  • Responsible for the development, implementation, and oversight of all policies, procedures, programs, and regulatory compliance within assigned clinics.
  • Collects, maintains, and analyzes data/data systems for regulatory and operational improvements.
  • Facilitates needs for adding new services lines within assigned clinics.
  • Establishes and maintains a system of reporting on operational and financial outcomes for assigned clinics.
  • Establishes and guides patient satisfaction goals within assigned clinics.

Leadership and Communication
  • Establish effective two-way communication with physicians, leadership, and employees.
  • Shares information in a clear and concise manner.
  • Is open to feedback.
  • Develops the ability of others to perform and contribute to the organization by providing ongoing feedback.
  • Builds strong relationships with physicians and employees.
  • Provides challenging assignments and opportunities for others to grow.
  • Takes the time to coach, mentor, and support others.
  • Manages and resolves conflicts in a positive and constructive manner.
  • Sets clear expectations and direction to his/her team.

JCMG Core Competencies:
  • Strives for continuous quality improvement.
  • Participates in educational experiences designed to maintain and/or improve professional competence.
  • Maintains high work ethic standards.
  • Provides quality customer service to staff, patients, and visitors at all times.

MINIMUM QUALIFICATIONS
Education:
  • Bachelor Degree in Healthcare Administration, Business Administration, Nursing, or related area required.
  • Master's degree preferred.

Experience:
  • Minimum of 3-5 years in healthcare/medical practice administration.

WORK ENVIRONMENT
Work is normally performed in an interior/office or workshop environment. Occasionally work involves driving to satellite locations.
BENEFITS
  • Health insurance & employer paid short- and long-term disability
  • Generous PTO policy, beginning at 148-hours annually
  • 56 hours paid Holiday Leave
  • Employer Retirement Plan (401K) with employer match
  • Tuition reimbursement and other professional advancements

Pay Range: $120,000 - $130,000 per year

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