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340B Program Manager Jobs (NOW HIRING)

340B Program Analyst Join the transformative team at City of Hope, where we're changing lives and ... Configure and manage 340B cost updates and med lists in Epic. * Provide expertise in building and ...

340B Program Analyst Join the transformative team at City of Hope, where we're changing lives and ... Configure and manage 340B cost updates and med lists in Epic. * Provide expertise in building and ...

Such management and coordination include ensuring compliance with all federal regulations and ... The 340B Program Coordinator works with the Director of Pharmacy and the Shared Services Director ...

340B Program Analyst

Evanston, IL · On-site

$68K - $99K/yr

Responsibilities The 340B Program Analyst is responsible for daily monitoring and operation of 340B ... management software preferred. The company is dedicated to empowering its staff with a ...

340B Program Analyst

Evanston, IL · On-site

$68K - $99K/yr

The 340B Program Analyst is responsible for daily monitoring and operation of 340B program services ... management software preferred. The company is dedicated to empowering its staff with a ...

Such management and coordination include ensuring compliance with all federal regulations and ... The 340B Program Coordinator works with the Director of Pharmacy and the Shared Services Director ...

The 340B Specialist along with the Director of Pharmacy, supports the strategic oversight, operational management, compliance, auditing, education, and optimization of Vail Health's 340B Program.

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340B Program Manager information

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$38.5K

$107.5K

$157K

How much do 340b program manager jobs pay per year?

As of Sep 2, 2026, the average yearly pay for 340b program manager in the United States is $107,460.00, according to ZipRecruiter salary data. Most workers in this role earn between $79,500.00 and $132,500.00 per year, depending on experience, location, and employer.

What is a 340B program manager?

A 340B Program Manager is a healthcare professional responsible for overseeing the administration and compliance of the 340B Drug Pricing Program within a hospital or healthcare organization. Their duties include managing program operations, ensuring regulatory compliance, optimizing program benefits, and acting as a liaison between departments, pharmacies, and external partners. The 340B Program Manager also tracks inventory, monitors audits, and implements policies to maximize cost savings while maintaining program integrity. They play a crucial role in helping covered entities provide affordable medications to underserved patient populations.

What are the key skills and qualifications needed to thrive as a 340B program manager?

To thrive as a 340B Program Manager, you need in-depth knowledge of pharmacy operations, 340B program compliance, and regulatory requirements, typically supported by a healthcare or pharmacy-related degree. Familiarity with 340B software platforms, data analytics tools, and auditing systems is crucial for managing program integrity. Strong organizational skills, attention to detail, and effective communication help ensure compliance and foster collaboration across departments. These skills are important to maximize program savings, minimize risk, and maintain adherence to complex federal regulations.

What are some common challenges faced by 340B program managers, and how can they address them?

340B Program Managers often encounter challenges related to maintaining program compliance, keeping up with evolving regulations, and ensuring accurate data management. Navigating audits and coordinating with multiple departments—such as pharmacy, finance, and compliance—require strong organizational and communication skills. Staying current with policy updates and leveraging specialized 340B software can help address these challenges, as can participating in ongoing training and networking with peers. Building strong internal processes and fostering collaboration across teams are key strategies for success in this role.

What is the difference between 340B Program Manager vs 340B Compliance Specialist?

Aspect340B Program Manager340B Compliance Specialist
CredentialsRelevant healthcare or pharmacy certifications, experience in 340B programsSimilar certifications, focus on compliance and regulatory knowledge
Work EnvironmentOversees program implementation, collaborates with departmentsFocuses on monitoring, audits, and ensuring adherence to regulations
Employer & IndustryHospitals, health systems, pharmacies involved in 340BHealthcare providers, pharmacy organizations, compliance firms

The 340B Program Manager typically leads the overall 340B program, managing strategy and operations, while the 340B Compliance Specialist focuses on ensuring adherence to regulations through audits and monitoring. Both roles require similar certifications and work within healthcare organizations involved in 340B, but their primary responsibilities differ in scope and focus.

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Infographic showing various 340B Program Manager job openings in the United States as of August 2026, with employment types broken down into 100% Full Time. Highlights an 76% In-person, 12% Hybrid, and 12% Remote job distribution, with an average salary of $107,460 per year, or $51.7 per hour.

Full-time

Posted 6 days ago


Job description

Job Requirements

Provides enterprise-wide strategic, financial, compliance, and operational leadership for the UMMS 340B program. Maximizes program value to provide care for vulnerable patient populations while maintaining the highest standards of regulatory compliance across covered entities, outpatient clinics, mixed-use settings, and contract pharmacy networks. C Leads governance, stakeholder alignment, and cross-functional decision-making. Translates evolving regulatory requirements into enterprise strategies and operational execution, ensuring program integrity, financial stewardship, risk mitigation, and sustainable growth across the organization.

 

Primary Responsibilities

The following statements are intended to describe the general nature and level of work being performed by people assigned to this classification. They are not to be construed as an exhaustive list of all job responsibilities performed.

      Lead the development and execution of the enterprise-wide 340B strategy, aligning program performance with organizational financial, compliance, and patient access objectives.

      Direct the strategy, evaluation, scale and optimization of contract pharmacy networks to improve financial performance, maximize eligible prescription capture, and reduce program leakage while maintaining compliance.

      Serve as the program authority by establishing, maintaining, and overseeing system-wide 340B governance, policies, and procedures to ensure program integrity and regulatory compliance across all covered entities.

      Oversee 340B program registration, recertification, and maintenance activities within the HRSA Office of Pharmacy Affairs Information System (OPAIS), ensuring complete and accurate records across all participating entities.

      Primary organizational liaison and contact for Health Resources and Services Administration (HRSA), state Medicaid, manufacturer, and other regulatory audits, directing audit response activities and implementation of corrective action plans when necessary.

      Responsible for the 340B financial portfolio, including program savings, margin performance, contract pharmacy yield, and growth opportunities. Develop and present performance metrics, forecasts, and recommendations to senior leadership and governance committees.

      Lead, mentor, direct and develop a team of 340B professionals, establishing performance expectations, accountability measures, and succession planning strategies.

      Manage technical relationships with third-party split-billing vendors and other external partners, ensuring optimal software performance, correct crosswalk mapping, and accurate data feeds.

      Lead enterprise 340B governance and multidisciplinary committees, driving strategic decision-making, stakeholder alignment, and accountability for program performance and compliance.

      Perform all other duties as assigned.


Work Experience

Education & Experience - Required

      Bachelor's degree in Pharmacy, Healthcare Administration, Business Administration, Finance, or a related field required.

      Apexus Certified Expert (340B ACE) certification required within 12 months of hire.

      Seven (7) years of progressive healthcare experience, including at least 5 years of direct 340B program leadership experience within an integrated delivery network (IDN), academic medical center, or multi-site health system.

      Demonstrated expertise in 340B regulatory requirements, program optimization, contract pharmacy administration, audit management, and compliance oversight.

      Experience leading cross-functional teams, governance committees, and enterprise-wide initiatives involving pharmacy, finance, compliance, revenue cycle, information technology, and clinical operations.

      Proven ability to analyze complex financial and operational data, develop strategic recommendations, and communicate effectively with executive leadership.

Education & Experience - Preferred

      Doctor of Pharmacy (Pharm.D.), Master of Business Administration (MBA), Master of Healthcare Administration (MHA), or other relevant advanced degree.

      Apexus Certified Expert (340B ACE) certification at the time of hire.

      Experience leading enterprise-wide 340B programs in a complex health system, academic medical center, or integrated delivery network.

      Experience with contract pharmacy optimization, audit management, and 340B technology platforms.

      Demonstrated ability to lead cross-functional governance committees and influence executive decision-making.


Employment Type: FULL_TIME