The successful candidate will lead development and optimization of downstream purification processes supporting viral vector programs from research through preclinical development. The ideal ...
The successful candidate will lead development and optimization of downstream purification processes supporting viral vector programs from research through preclinical development. The ideal ...
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$32 - $41/hr
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gRNA Process Development Scientist
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Position description Process Development Scientist The Department of Laboratory Medicine at the University of California, San Francisco(UCSF) is seeking a motivated Process Development Scientist to ...
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Take 5S/process improvement initiatives. * Monitor Product Yields daily and work with appropriate engineers to take corrective actions when trends indicate equipment and/or process issues. * Work ...
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The Rubber Process Development Chemist is a key member of the Research & Development (R&D) team and is responsible for developing and improving rubber compounds and processing methods for the ...
The Rubber Process Development Chemist is a key member of the Research & Development (R&D) team and is responsible for developing and improving rubber compounds and processing methods for the ...
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May include participation in procedure drafting, revision and process improvement. May require performing tasks following cGMP guidelines. May require participation in inventory receipt/warehousing ...
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Process Development Associate I - Downstream
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$55K - $75K/yr
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Process Development Engineer II
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Job Title: R&D Process Development Specialist Location: Chicago, IL 60642 Duration: 12 Months (Possible Extension) Position Summary We are seeking a Process Development Specialist to join our R&D ...
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Job Title: R&D Process Development Specialist Location: Chicago, IL 60642 Duration: 12 Months (Possible Extension) Position Summary We are seeking a Process Development Specialist to join our R&D ...
The Process Development Engineer II position is primarily responsible for designing, developing, and qualifying manufacturing processes, consisting of multiple engineering disciplines, for the ...
The Process Development Engineer II position is primarily responsible for designing, developing, and qualifying manufacturing processes, consisting of multiple engineering disciplines, for the ...
The Process Development Engineer II position is primarily responsible for designing, developing, and qualifying manufacturing processes, consisting of multiple engineering disciplines, for the ...
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Company Description A Few Words About Us Integrated Resources, Inc is a premier staffing firm recognized as one of the tri-states most well-respected professional specialty firms. IRI has built its ...
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This Formulation & Process Development role provides the opportunity to influence products from concept through commercialization while working across diverse regulated product categories including ...
Quick apply
This Formulation & Process Development role provides the opportunity to influence products from concept through commercialization while working across diverse regulated product categories including ...
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Principal Process Development Engineer
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Principal Process Development Engineer
Murrieta, CA · On-site
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Process Development Engineer II
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We are seeking a Process Development Engineer II to join our dynamic team at our Plymouth, MN facility. This role is ideal for an engineer who thrives in a hands-on, fast-paced environment and is ...
Process Development Engineer II
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We are seeking a Process Development Engineer II to join our dynamic team at our Plymouth, MN facility. This role is ideal for an engineer who thrives in a hands-on, fast-paced environment and is ...
Process Development information
See salary details
$18.99 - $21.77
3% of jobs
$21.77 - $24.54
6% of jobs
$24.54 - $27.32
12% of jobs
$27.79 is the 25th percentile. Wages below this are outliers.
$27.32 - $30.09
23% of jobs
The median wage is $31.18 / hr.
$30.09 - $32.87
15% of jobs
$32.87 - $35.64
15% of jobs
$36.80 is the 75th percentile. Wages above this are outliers.
$35.64 - $38.42
3% of jobs
$38.42 - $41.19
3% of jobs
$41.19 - $43.97
6% of jobs
$43.97 - $46.74
3% of jobs
$46.74 - $49.52
11% of jobs
$18
$33
$49
How much do process development jobs pay per hour?
What are the key skills and qualifications needed to thrive as a Process Development professional, and why are they important?
What is the difference between Process Development vs Process Engineering?
| Aspect | Process Development | Process Engineering |
|---|---|---|
| Focus | Designing and optimizing new processes for products or manufacturing | Implementing, maintaining, and improving existing processes |
| Work Stage | Early-stage process creation and testing | Scaling up, troubleshooting, and sustaining processes |
| Skills & Certifications | Chemical/biochemical engineering, lab skills, process modeling | Process optimization, quality control, engineering principles |
Process Development primarily focuses on creating and refining new processes, while Process Engineering emphasizes implementing and maintaining those processes in production. Both roles require similar technical backgrounds but differ in their stage of involvement within the product lifecycle.
What is process development?
What are the main challenges faced by professionals in Process Development, and how are they typically addressed?

Full-time
Medical, Dental, Vision, Life, Retirement, PTO
Posted 12 days ago
Eli Lilly and Company rating
8.8
Based on 62 frontline employees who took The Breakroom Quiz
11th of 71 rated pharmaceutical
Job description
We are seeking a highly motivated Principal Engineer to join the Downstream Process Development team. The successful candidate will lead development and optimization of downstream purification processes supporting viral vector programs from research through preclinical development.
The ideal candidate will possess deep technical expertise in downstream purification technologies including ultracentrifugation, chromatography, and tangential flow filtration (TFF), with demonstrated experience driving process development strategies, platform development initiatives, technology implementation, and multi-functional collaboration.
This role requires strong scientific leadership, hands-on technical capability, and the ability to independently lead complex purification development activities in a fast-paced environment.
Key Responsibilities
- Lead development, optimization, and scale-up of downstream purification workflows for viral vectors.
- Design and implement purification strategieusingng Iodixanol and CsCl density gradient ultracentrifugation, affinity chromatography, ion-exchange chromatography (AEX/CEX), membrane chromatography, and polishing operations.
- Lead AKTA-based chromatography workflow development and process intensification initiatives.
- Develop scalable downstream platform approaches to support rapid material generation and process consistency across programs.
- Independently design experiments, analyze data, interpret results, and present technical conclusions to multi-functional teams and leadership.
- Drive troubleshooting, process characterization, and process robustness studies.
- Collaborate closely with upstream, analytical, manufacturing, and external partners to support program deliverables and timelines.
- Support technology transfer, process documentation, and development reports.
- Lead development and optimization of TFF/UFDF workflows for concentration, buffer exchange, formulation, and process scalability.
- Mentor junior scientists/engineers and provide technical guidance across purification activities.
- Contribute to implementation of new purification technologies, automation tools, and continuous process improvements.
- Ensure compliance with safety, documentation, and quality standards.
Basic Qualifications
- Master's degree in biology, biochemistry, chemical engineering, biotechnology or related field
- 8+ years of relevant downstream process development experience in industry
- Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1.
Additional Skills/Preferences:
- CsCl and iodixanol ultracentrifugation
- Affinity chromatography
- Ion-exchange chromatography
- TFF/UFDF operations including concentration, diafiltration, and formulation development
- AKTA systems and Unicorn software
- Strong understanding of process scale-up, platform development, and purification process characterization.
- Experience analyzing purification performance and product quality attributes using relevant analytical methods.
- Experience in AAV downstream process development and capsid enrichment workflows.
- Experience with automated chromatography systems and process intensification strategies.
- Experience supporting technology transfer and manufacturing readiness activities.
- Familiarity with GMP development environments and regulatory expectations.
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups.
Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$71,250 - $187,000
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
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About Eli Lilly
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Eli Lilly, based in Indianapolis, IN, US, is one of the pioneers in the pharmaceutical industry with a rich history dating back to 1876. This global pharmaceutical company focuses on discovering, developing, manufacturing and selling pharmaceutical products in approximately 120 countries. The company's product categories include endocrinology, oncology, cardiovascular, neuroscience, and immunology. Having invested over $9 billion in research and development in the past decade, Eli Lilly is also committed to creating high-quality medicines that meet real needs. As a recipient of several awards and recognitions, Eli Lilly is known for its focus on life-saving research and drug development. Their mission is to make medicines that help people live longer, healthier, and more active lives.
Industry
Pharmaceutical product wholesalers
Company size
10,000+ Employees
Headquarters location
Indianapolis, IN, US
Year founded
1876