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Director Clinical Operations Jobs (NOW HIRING)

Job Summary The Director, Clinical Operations will oversee the planning, execution, and delivery of clinical trials, initially focusing on our Yutrepia program, ensuring alignment with corporate ...

Finally, the Senior Director, Clinical Operations will oversee implementation of all clinical trial activities utilizing both internal and external resources. Performance Objectives: Develops the ...

Finally, the Senior Director, Clinical Operations will oversee implementation of all clinical trial activities utilizing both internal and external resources. Performance Objectives: * Develops the ...

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Director Clinical Operations information

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$60K

$146K

$282.5K

How much do director clinical operations jobs pay per year?

As of Jun 8, 2026, the average yearly pay for director clinical operations in the United States is $145,969.00, according to ZipRecruiter salary data. Most workers in this role earn between $102,000.00 and $173,500.00 per year, depending on experience, location, and employer.

What Does a Director of Clinical Operations Do?

A director of clinical operations manages the daily operations of a healthcare facility or a specific department within a clinic or hospital. As a director of clinical operations, your responsibilities include scheduling staff to ensure proper coverage of patients and overseeing the productivity of your team to meet the organization's expectations. You define policies and procedures, facilitating further training when necessary. The director of clinical operations must also assess the performance of the medical team under your supervision regularly and mainstream processes when possible. Medical device manufacturers and pharmaceutical companies often hire a director of clinical operations to oversee research, lab, and testing operations.

What are the key skills and qualifications needed to thrive as a Director of Clinical Operations, and why are they important?

To thrive as a Director of Clinical Operations, you need a robust background in clinical management, regulatory compliance, and healthcare administration, often supported by a relevant degree and substantial leadership experience. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) tools, and certifications like PMP or CCRA are commonly required. Exceptional leadership, strategic thinking, and communication skills help drive teams, manage stakeholders, and oversee complex projects. These skills are critical for ensuring clinical programs run efficiently, meet regulatory standards, and deliver high-quality patient outcomes.

What is the difference between Director Clinical Operations vs Clinical Project Manager?

AspectDirector Clinical OperationsClinical Project Manager
CredentialsTypically requires advanced degrees (e.g., MS, PhD) and extensive industry experienceUsually holds a bachelor's or master's degree in a related field, with relevant project management certifications
Work EnvironmentOversees multiple projects and teams across departments, strategic planningManages individual clinical trials, coordinates project activities, and timelines
Employer & Industry UsageUsed in pharmaceutical, biotech, and healthcare companies for senior leadership rolesCommonly employed in clinical research organizations and pharmaceutical companies for trial management

The main difference is that the Director Clinical Operations focuses on strategic oversight and leadership across multiple clinical trials, while the Clinical Project Manager handles the day-to-day management of specific clinical studies. Both roles require strong industry knowledge, but the director position involves broader responsibilities and higher-level decision-making.

What does a Director of Clinical Operations do?

A Director of Clinical Operations is responsible for overseeing the day-to-day management and strategic direction of clinical trials and research activities within healthcare organizations or pharmaceutical companies. They ensure that clinical studies are conducted efficiently, ethically, and in compliance with regulatory requirements. This role involves supervising teams, managing budgets, developing protocols, and liaising with stakeholders to ensure successful trial outcomes. Directors of Clinical Operations play a crucial role in bringing new medical treatments to market by ensuring studies run smoothly from start to finish.

How does a Director of Clinical Operations typically collaborate with cross-functional teams to ensure successful clinical trial execution?

A Director of Clinical Operations regularly collaborates with cross-functional teams such as regulatory affairs, data management, medical affairs, and biostatistics to ensure clinical trials are executed on time, within budget, and in compliance with regulations. This role involves leading team meetings, aligning project timelines, and facilitating communication between internal stakeholders and external partners like CROs and vendors. Strong coordination skills are essential, as the Director must balance diverse priorities and resolve any operational issues that arise, ensuring all teams work toward shared objectives.
What cities are hiring for Director Clinical Operations jobs? Cities with the most Director Clinical Operations job openings:
What are the most commonly searched types of Clinical Operations jobs? The most popular types of Clinical Operations jobs are:
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Director, Clinical Operations

Director, Clinical Operations

COPE Health Solutions

Los Angeles, CA โ€ข On-site

$172K - $211K/yr

Full-time

Posted 7 hours ago


Job description

Description
This position requires a forward-thinking leader with a comprehensive understanding of clinical operations, regulatory compliance, and quality improvement. The Clinical Operations Director plays a critical role in ensuring high-quality patient care, operational efficiency, and alignment with organizational goals.
FLSA Status
Exempt
Salary Range
$172,100 - $211,575
Reports To
Principal and Executive Vice President
Direct Reports
LVN, LCSW, LMSW (clinical team)
Location
Hybrid in LA Office
Travel
Up to 80%
Work Type
Regular
Schedule
Full Time
Key Duties and Responsibilities
  • Provide strategic oversight for the planning, implementation, and evaluation of clinical programs from initiation through completion.
  • Develop and execute operational strategies to enhance clinical performance, efficiency, and quality of care.
  • Ensure clinical services and team practices are conducted in accordance with ethical standards, organizational policies, and all regulatory and accreditation requirements.
  • Collaborate with providers, nursing staff, and non-clinical leadership to implement policies, strengthen clinical workflows, and improve service delivery.
  • Coordinate across departments to ensure clinical programs operate effectively, efficiently, and in alignment with organizational objectives.
  • Lead and manage clinical operations staff, including recruitment, onboarding, training, coaching, and performance management.
  • Oversee clinical quality initiatives, including audits, incident reporting, root cause analyses, and infection prevention and control programs.
  • Develop and implement staff education and training initiatives to ensure adherence to clinical standards, best practices, and regulatory requirements.
  • Monitor and analyze quality metrics, dashboards, and performance data to identify trends, address gaps in care, and improve clinical outcomes.
  • Build and maintain collaborative relationships with external partners, including community-based organizations, health plans, regulatory bodies, and healthcare providers.
  • Ensure readiness for regulatory reviews, audits, and accreditation processes.
  • Support a culture of accountability, continuous improvement, and patient-centered care.

Qualifications
  • Active Registered Nurse (RN) license required.

  • Bachelor's degree in Nursing (BSN) or a related healthcare field required.
  • Master's degree in Nursing (MSN), Healthcare Administration (MHA), Public Health (MPH), or related field preferred.
  • Minimum of 5-10 years of progressive clinical experience, including significant leadership or management experience in clinical operations, quality assurance, or healthcare program management.
  • Strong knowledge of Medicare and Medicaid regulations, accreditation standards, and healthcare risk management practices.
  • Demonstrated leadership, analytical, communication, and problem-solving skills.
  • Proven ability to manage multiple priorities and projects in a fast-paced, high-demand healthcare environment.
  • Strong commitment to quality, compliance, and organizational success.
  • Ability to work collaboratively across multidisciplinary teams.
  • Flexibility to work varied hours, including evenings or weekends as needed, and willingness to travel when required.

Working Conditions
  • Office and hybrid working environment
  • 80% of travel requirements for meetings, site visits, satellite offices as required.

COPE Health Solutions reserves the right to modify the job description based upon its needs and may require the employee to perform functions beyond those mentioned above. Neither this job description nor any other communication creates an employment contract between the Company and the employee.
Equal Employment
Our culture encourages individual development, embraces an inclusive environment, rewards innovative excellence. COPE Health Solutions values diversity, inclusion, and equity as matters of fairness and effectiveness. We are committed to hiring and retaining a staff that reflects the diversity of the communities we serve, fostering an inclusive working environment where staff of all backgrounds feel welcomed and engaged.
COPE Health Solutions is an Equal Opportunity Employer and encourages applications from individuals underrepresented in the medical sector, including people of color, and persons with non-traditional work and educational experience. All who believe they meet the stated qualifications are invited to apply.
Benefits:
As a firm passionate about health care, we're deeply committed to the health and wellness of our own team members. We offer comprehensive, affordable insurance plans for our team and their families, and a host of other unique benefits, such as a yearly stipend for wellness-related activities and a paid parental leave program. You can learn more about our benefits offerings here: https://copehealthsolutions.com/careers/why-cope-health-solutions/.
About COPE Health SolutionsCOPE Health Solutions is a national tech-enabled services firm powering success for health plans and for providers in risk arrangements. Our comprehensive NCQA certified population health management platform and highly experienced team brings deep expertise, experience, proven tools, and processes to improve financial performance and quality outcomes for all types of payers and providers. CHS de-risks the roadmap to advanced value-based payment and improves quality and financial performance for providers, health plans and self-insured employers. For more information, visit CopeHealthSolutions.com.
To Apply:
To apply for this position or for more information about COPE Health Solutions, visit us at https://copehealthsolutions.com/careers/open-positions/.