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Director Clinical Operations Jobs (NOW HIRING)

Gilead

Director, Clinical Operations

Foster City, CA

$210K - $272K/yr

Experience managing cross-functional teams or work groups as well as direct reports. * Demonstrated understanding of pharmaceutical regulatory requirements and impact on development of clinical ...

Gilead

Director, Clinical Operations

Parsippany, NJ · On-site

$210K - $272K/yr

Experience managing cross-functional teams or work groups as well as direct reports. * Demonstrated understanding of pharmaceutical regulatory requirements and impact on development of clinical ...

Gilead

Director, Clinical Operations

Foster City, CA

$210K - $272K/yr

Experience managing cross-functional teams or work groups as well as direct reports. * Demonstrated understanding of pharmaceutical regulatory requirements and impact on development of clinical ...

Immatics NV

Director, Clinical Operations Lead

Houston, TX · On-site

$215K - $260K/yr

The Director, Clinical Operations Lead will be responsible for the oversight, execution, and operational management of global clinical trials in support of our clinical development programs. Schedule ...

taiho

Sr. Director, Clinical Operations

Pleasanton, CA · Hybrid

Finally, the Senior Director, Clinical Operations will oversee implementation of all clinical trial activities utilizing both internal and external resources. Performance Objectives: * Develops the ...

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Director Clinical Operations information

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How much do director clinical operations jobs pay per year?

As of Jul 20, 2026, the average yearly pay for director clinical operations in the United States is $145,969.00, according to ZipRecruiter salary data. Most workers in this role earn between $102,000.00 and $173,500.00 per year, depending on experience, location, and employer.

What Does a Director of Clinical Operations Do?

A director of clinical operations manages the daily operations of a healthcare facility or a specific department within a clinic or hospital. As a director of clinical operations, your responsibilities include scheduling staff to ensure proper coverage of patients and overseeing the productivity of your team to meet the organization's expectations. You define policies and procedures, facilitating further training when necessary. The director of clinical operations must also assess the performance of the medical team under your supervision regularly and mainstream processes when possible. Medical device manufacturers and pharmaceutical companies often hire a director of clinical operations to oversee research, lab, and testing operations.

What are the key skills and qualifications needed to thrive as a Director of Clinical Operations, and why are they important?

To thrive as a Director of Clinical Operations, you need a robust background in clinical management, regulatory compliance, and healthcare administration, often supported by a relevant degree and substantial leadership experience. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) tools, and certifications like PMP or CCRA are commonly required. Exceptional leadership, strategic thinking, and communication skills help drive teams, manage stakeholders, and oversee complex projects. These skills are critical for ensuring clinical programs run efficiently, meet regulatory standards, and deliver high-quality patient outcomes.

What is the difference between Director Clinical Operations vs Clinical Project Manager?

AspectDirector Clinical OperationsClinical Project Manager
CredentialsTypically requires advanced degrees (e.g., MS, PhD) and extensive industry experienceUsually holds a bachelor's or master's degree in a related field, with relevant project management certifications
Work EnvironmentOversees multiple projects and teams across departments, strategic planningManages individual clinical trials, coordinates project activities, and timelines
Employer & Industry UsageUsed in pharmaceutical, biotech, and healthcare companies for senior leadership rolesCommonly employed in clinical research organizations and pharmaceutical companies for trial management

The main difference is that the Director Clinical Operations focuses on strategic oversight and leadership across multiple clinical trials, while the Clinical Project Manager handles the day-to-day management of specific clinical studies. Both roles require strong industry knowledge, but the director position involves broader responsibilities and higher-level decision-making.

What does a Director of Clinical Operations do?

A Director of Clinical Operations is responsible for overseeing the day-to-day management and strategic direction of clinical trials and research activities within healthcare organizations or pharmaceutical companies. They ensure that clinical studies are conducted efficiently, ethically, and in compliance with regulatory requirements. This role involves supervising teams, managing budgets, developing protocols, and liaising with stakeholders to ensure successful trial outcomes. Directors of Clinical Operations play a crucial role in bringing new medical treatments to market by ensuring studies run smoothly from start to finish.

How does a Director of Clinical Operations typically collaborate with cross-functional teams to ensure successful clinical trial execution?

A Director of Clinical Operations regularly collaborates with cross-functional teams such as regulatory affairs, data management, medical affairs, and biostatistics to ensure clinical trials are executed on time, within budget, and in compliance with regulations. This role involves leading team meetings, aligning project timelines, and facilitating communication between internal stakeholders and external partners like CROs and vendors. Strong coordination skills are essential, as the Director must balance diverse priorities and resolve any operational issues that arise, ensuring all teams work toward shared objectives.
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Director Clinical Operations jobs near you
Infographic showing various Director Clinical Operations job openings in the United States as of July 2026, with employment types broken down into 100% Full Time. Highlights an 50% In-person, and 50% Remote job distribution, with an average salary of $145,969 per year, or $70.2 per hour.
Associate Director Clinical Operations

Associate Director Clinical Operations

System One

Waltham, MA • On-site

Contractor

Medical, Dental, Vision, Life, Retirement

Posted 12 days ago

Job description

Job Title: Associate Director Clinical Operations Location: Waltham, Massachusetts Type: Perm Work Model: Hybrid – 2 days onsite in Waltham Leading Pharmaceutical Company located in MA is hiring a Associate Director Clinical Operations w/ 5+ years industry experience. If you want to be a part of this groundbreaking work, please apply! Responsibilities

  • Provide leadership and guidance to clinical trial teams supporting innovative advanced therapy clinical trials.
  • Collaborate with internal cross-functional teams, clinical sites, and CRO partners to execute global clinical programs in a safe, ethical, and compliant manner.
  • Ensure trials adhere to ICH GCP, federal, international, and local regulatory requirements.
  • Manage and forecast trial budgets and timelines, ensuring alignment with company objectives.
  • Partner with US, EU, and international colleagues, CROs, and investigators to identify risks and develop effective trial plans.
  • Develop high-quality study deliverables such as Protocols, CRFs, SAPs, CSRs, and manuals.
  • Evaluate KPIs, KRIs, and SOPs; identify gaps and propose solutions for compliance and efficiency.
  • Contribute to regulatory filings domestically and internationally.
  • Mentor and develop Clinical Operations team members, participating in staffing, performance management, and talent development.
  • Interact regularly with senior management on project and departmental initiatives.
  • May oversee a team to achieve organizational goals.
Requirements
  • Bachelor’s Degree in Life Sciences or related field
  • 10+ years of progressive experience in clinical operations, with at least 5 years in a biopharmaceutical organization
  • Experience overseeing CRO selection, contracting, and management
  • Thorough understanding of GCP and ICH regulations, clinical trial monitoring, and compliance
  • Prior experience in advanced therapies clinical research is desirable
  • Strong written and verbal communication skills
  • Ability to work cross-departmentally and cross-functionally
  • Competent in data management, interpretation, and communication
  • Excellent interpersonal, conflict resolution, decision-making, and delegation skills
  • Occasional travel (up to 5%)

System One, and its subsidiaries including Joulé and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan. System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law. #M- #LI-

Ref: #568-Clinical