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How much do associate director clinical operations jobs pay per year?

As of Sep 10, 2026, the average yearly pay for associate director clinical operations in the United States is $145,969.00, according to ZipRecruiter salary data. Most workers in this role earn between $102,000.00 and $173,500.00 per year, depending on experience, location, and employer.

What does an associate director clinical operations do?

An Associate Director of Clinical Operations oversees the planning, execution, and management of clinical trials within a pharmaceutical, biotechnology, or medical device company. They supervise clinical project teams, ensure regulatory compliance, manage budgets and timelines, and collaborate with cross-functional departments to deliver high-quality results. Their role is crucial in ensuring that clinical studies are conducted efficiently, safely, and in accordance with all applicable guidelines and standards.

How does an associate director clinical operations typically collaborate with cross-functional teams during a clinical trial?

An Associate Director of Clinical Operations regularly works alongside teams such as Regulatory Affairs, Data Management, Medical Affairs, and Biostatistics to ensure trials run smoothly and meet compliance standards. They coordinate project timelines, facilitate communication between departments, and address operational challenges as they arise. This collaborative approach helps to streamline decision-making, resolve issues quickly, and keep the clinical trial on track for successful completion.

What are the key skills and qualifications needed to thrive as an associate director clinical operations, and why are they important?

To thrive as an Associate Director Clinical Operations, you need expertise in clinical trial management, regulatory compliance, and strong leadership, typically supported by a degree in life sciences or a related field. Familiarity with clinical trial management systems (CTMS), GCP guidelines, and project management tools is essential, along with relevant certifications like PMP or ACRP. Exceptional communication, problem-solving, and team-building skills enable effective cross-functional collaboration and decision-making. These skills are vital for ensuring the successful planning, execution, and oversight of clinical trials while meeting regulatory and organizational goals.

What is the difference between Associate Director Clinical Operations vs Clinical Project Manager?

AspectAssociate Director Clinical OperationsClinical Project Manager
ResponsibilitiesOversees multiple clinical trials, manages teams, and ensures regulatory complianceManages individual clinical projects, coordinates activities, and tracks progress
Required CredentialsBachelor's or higher in life sciences, often with experience in clinical operationsBachelor's in life sciences, with project management experience
Work EnvironmentSenior-level role within clinical operations teams, often in biotech or pharma companiesProject-focused role, working closely with cross-functional teams in clinical settings

The Associate Director Clinical Operations typically oversees multiple clinical trials and manages teams, requiring broader strategic oversight. In contrast, a Clinical Project Manager focuses on managing specific projects, ensuring timely execution. Both roles require relevant clinical experience, but the Associate Director role involves higher-level leadership and operational responsibilities.

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Associate Director Clinical Operations jobs near you
Infographic showing various Associate Director Clinical Operations job openings in the United States as of September 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $145,969 per year, or $70.2 per hour.

Associate Director Clinical Operations

Waltham, MA • Remote

System One
Business Consulting Services • 5 - 10K employees
Learn more about System Oneexternal

Contractor

Medical, Dental, Vision, Life, Retirement

Re-posted 5 days ago

Job description

Job Title: Associate Director Clinical Operations Location: Waltham, Massachusetts Type: Perm Work Model: Hybrid – onsite and remote Leading Pharmaceutical Company located in MA is hiring a Associate Director Clinical Operations w/ 5+ years industry experience. If you want to be a part of this groundbreaking work, please apply! Responsibilities

  • Provide leadership and guidance to clinical trial teams supporting innovative advanced therapy clinical trials.
  • Collaborate with internal cross-functional teams, clinical sites, and CRO partners to execute global clinical programs in a safe, ethical, and compliant manner.
  • Ensure trials adhere to ICH GCP, federal, international, and local regulatory requirements.
  • Manage and forecast trial budgets and timelines, ensuring alignment with company objectives.
  • Partner with US, EU, and international colleagues, CROs, and investigators to identify risks and develop effective trial plans.
  • Develop high-quality study deliverables such as Protocols, CRFs, SAPs, CSRs, and manuals.
  • Evaluate KPIs, KRIs, and SOPs; identify gaps and propose solutions for compliance and efficiency.
  • Contribute to regulatory filings domestically and internationally.
  • Mentor and develop Clinical Operations team members, participating in staffing, performance management, and talent development.
  • Interact regularly with senior management on project and departmental initiatives.
  • May oversee a team to achieve organizational goals.
Requirements
  • Bachelor’s Degree in Life Sciences or related field
  • 10+ years of progressive experience in clinical operations, with at least 5 years in a biopharmaceutical organization
  • Experience overseeing CRO selection, contracting, and management
  • Thorough understanding of GCP and ICH regulations, clinical trial monitoring, and compliance
  • Prior experience in advanced therapies clinical research is desirable
  • Strong written and verbal communication skills
  • Ability to work cross-departmentally and cross-functionally
  • Competent in data management, interpretation, and communication
  • Excellent interpersonal, conflict resolution, decision-making, and delegation skills
  • Occasional travel (up to 5%)

System One, and its subsidiaries including Joulé and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan. System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law. #M- #LI-

Ref: #568-Clinical

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About System One

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System One helps employers get work done more efficiently and economically without compromising quality. Over our 35+ year history, we've helped connect thousands of talented people with innovative companies. The excitement of a perfect fit motivates us every single day.

Industry

Business consulting services and recruiting and staffing services

Company size

5,001 - 10,000 Employees

Headquarters location

Pittsburgh, PA, US

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