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Vice President Technical Operations Jobs (NOW HIRING)

Stackinfra

Vice President, Technical Operations

Plano, TX · On-site

$216K - $249K/yr

STACK is looking for a Vice President of Technical Operations to support all data centers across the Americas portfolio. As a leader within STACK's Operations team, the Vice President of Technical ...

Stackinfra

Vice President, Technical Operations

Denver, CO · On-site +1

$216K - $249K/yr

STACK is looking for a Vice President of Technical Operations to support all data centers across the Americas portfolio. As a leader within STACK's Operations team, the Vice President of Technical ...

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How much do vice president technical operations jobs pay per year?

As of Sep 5, 2026, the average yearly pay for vice president technical operations in the United States is $155,780.00, according to ZipRecruiter salary data. Most workers in this role earn between $115,500.00 and $185,000.00 per year, depending on experience, location, and employer.

What is a vice president technical operations?

A Vice President of Technical Operations oversees an organization's technical infrastructure, ensuring efficiency, reliability, and scalability. They manage teams responsible for IT systems, engineering, and operational processes, aligning technology with business goals. This role involves strategic planning, process optimization, and risk management to enhance performance and productivity. Additionally, they collaborate with executives to implement technology-driven solutions, improve service delivery, and drive innovation.

What are some typical challenges a vice president technical operations may face in this role?

A Vice President Technical Operations often encounters challenges such as managing cross-functional teams across multiple locations, ensuring consistent and reliable technical service delivery, and balancing resource constraints while meeting business goals. Adapting to rapidly evolving technologies and integrating new systems or processes can also present complexities that require strategic foresight and problem-solving skills. Additionally, aligning technical operations with high-level company objectives and stakeholder expectations demands strong leadership and effective communication. By proactively addressing these challenges, you can drive operational excellence and make a significant impact on organizational growth.

What are the key skills and qualifications needed to thrive in the vice president technical operations position, and why are they important?

To thrive as a Vice President Technical Operations, you need deep expertise in operations management, technical acumen, strategic planning, and leadership, often complemented by a bachelor’s or master’s degree in engineering, computer science, or a related field. Familiarity with IT infrastructure, cloud platforms, project management tools (such as Jira or Asana), and frameworks like ITIL or Six Sigma is highly beneficial. Exceptional communication, decision-making, and team-building skills set standout candidates apart in this executive role. These competencies are crucial for aligning technical operations with business objectives, ensuring efficient processes, and leading high-performing teams.

What cities are hiring for Vice President Technical Operations jobs?

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What are the most commonly searched types of Technical Operations jobs?

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Vice President Technical Operations jobs near you
Infographic showing various Vice President Technical Operations job openings in the United States as of August 2026, with employment types broken down into 84% Full Time, 13% Part Time, 1% Temporary, 1% Contract, and 1% Nights. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $155,780 per year, or $74.9 per hour.

VP, Technical Operations

Scorpion Therapeutics

Waltham, MA • On-site

$291 - $360/hr

Other

Medical, Dental, Vision, Retirement, PTO

Posted 7 days ago

Job description

Summary

The Vice President, Technical Operations will lead end-to-end CMC Technical Operations strategy across Drug Substance, Drug Product, and CMC Program Management, advancing small-molecule products from candidate selection and IND-enabling development through clinical development, registration, validation, commercial launch, ongoing manufacturing, and lifecycle management.

Responsibilities
  • Lead and develop Technical Operations and CMC Program Management; integrate/prioritize/execute Drug Substance, Drug Product, and cross-functional CMC activities across the product lifecycle.
  • Develop and execute phase-appropriate CMC strategies (Drug Substance, Drug Product, analytical development, manufacturing, controls, stability, validation, regulatory CMC, supply) from IND-enabling through registration, commercialization, and post-approval lifecycle management.
  • Provide technical leadership for small-molecule Drug Product development (formulation/process development, scale-up, technology transfer, characterization, control strategy, validation/PPQ, commercial readiness).
  • Provide oversight for Drug Substance development/manufacturing (scale-up, technology transfer, validation, control strategy, commercial readiness, lifecycle support).
  • Ensure CMC Program Management across the portfolio (deliverables, dependencies, critical paths, risks, resources, budgets, governance, decisions).
  • Oversee CDMOs/external manufacturing partners for development, validation, and clinical/commercial manufacturing.
  • Lead commercial manufacturing and lifecycle management (investigations, CAPAs, change controls, improvements, site transfers, continued process verification, supply continuity).
  • Partner with Supply Chain, Regulatory Affairs, Quality, and Program leadership to meet FDA/ICH/global regulatory and cGMP expectations.
  • Represent Technical Operations in cross-functional teams, executive governance, due diligence, portfolio planning, and risk management.
  • Manage resources, operating plans, budgets, and portfolio priorities.
Qualifications
  • MS/Ph.D. in Pharmaceutics/Pharmaceutical Sciences/Chemical Engineering/Chemistry (or related) with progressive pharmaceutical industry experience for a VP-level role.
  • Extensive small-molecule development/manufacturing experience; deep Drug Product expertise (formulation/process development, scale-up, technology transfer, characterization, control strategy, validation/PPQ, regulatory approval, commercial launch, ongoing manufacturing), including leading PPQ/commercial validation at external sites.
  • Broad Drug Substance technical knowledge to lead and challenge an experienced organization.
  • Demonstrated end-to-end CMC strategy development and integration across Drug Substance, Drug Product, analytical, regulatory, quality, manufacturing, and supply.
  • Strong CMC program/portfolio management (risks, dependencies, resources, budgets, timelines, governance, executive decision support).
  • Significant CDMO/external manufacturing partner management experience.
  • Strong cGMP and FDA/ICH/global regulatory knowledge; experience supporting INDs, NDAs, and post-approval submissions.
  • Ability to lead multidisciplinary technical teams and influence senior stakeholders.
  • Small-molecule Drug Product development across multiple dosage forms (oral solids and liquids).
  • Commercial lifecycle management and global manufacturing network experience (post-approval changes, site transfers, optimization, supply risk, international submissions).
  • Technical due diligence experience for licensing/acquisitions/partnerships.
Compensation and Benefits
  • Targeted Base Salary: $291,349 USD - $359,902 USD.
  • Additional benefits include health care, vision, dental, retirement, PTO, etc.
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