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Information Systems Manager Jobs (NOW HIRING)

Mosaicms

IT Systems Manager

Salem, OR · On-site

$90 - $120/hr

We're looking for an IT Systems Manager who wants to be the person behind the scenes making sure our people, our data, and our communities stay secure, connected, and running smoothly. This isn't a ...

Kenco

Mgr - Information Systems

Chattanooga, TN · On-site

About the Position The Information Systems Manager is an integral part of the IT Infrastructure and Operations Team (I&O). This role will collaborate closely with the I&O team to troubleshoot ...

Workstream

IT Business Systems Manager

Indianapolis, IN · On-site

$75 - $105/hr

Paylocity (HRIS): Basic administration and data integrity between HR/payroll and the other systems. If you've configured a POS system, managed a multi-location menu rollout, or done GL/reporting ...

Magnolia ISD

Information Systems Analyst

Magnolia, TX · On-site

Delivers end-user support, manages Frontline SIS access, and creates enterprise software training materials for staff. Working alongside the Information Systems Administrator, the analyst helps ...

Tarter Gate Company, LLC

IT Systems Manager

Dunnville, KY · On-site

$75 - $95/hr

The IT Systems Manager will lead the strategic planning, implementation, and maintenance of the organization's IT infrastructure within the manufacturing sector. This role is critical in ensuring ...

Amphenol TCS

Program/Systems Manager

Yocumtown, PA · On-site

Bachelor's degree in Management Information Systems, Program Management with a strong focus on ... Computer System Development * 3+ years experience in Management Information Systems integration ...

CARABETTA COMPANIES

Yardi Systems Manager

Meriden, CT · On-site

$90K/yr

Collaborate with Property Management, IT, and Marketing to streamline processes and optimize system usage. * Managing relationships with Yardi support providers and coordinating maintenance ...

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Information Systems Manager information

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$44K

$105.8K

$149.5K

How much do information systems manager jobs pay per year?

As of Aug 29, 2026, the average yearly pay for information systems manager in the United States is $105,783.00, according to ZipRecruiter salary data. Most workers in this role earn between $80,000.00 and $129,500.00 per year, depending on experience, location, and employer.

What does an information systems manager do?

An information systems manager is an IT specialist who oversees the implementation and maintenance of an organization’s technology. Your duties are to manage a team of IT workers to install or upgrade hardware and software, develop security protocols and practices, and train other workers in how to use the technology. You often provide reports to upper management about the health and safety of the IT systems and make recommendations for improvement. Some information systems managers specialize in a specific area of IT, such as security or networks, while others oversee the operations of the entire system.

What are the key skills and qualifications needed to thrive as an information systems manager, and why are they important?

To thrive as an Information Systems Manager, you need a strong background in IT infrastructure, systems analysis, and project management, often supported by a degree in computer science or information systems. Familiarity with enterprise resource planning (ERP) systems, network management tools, and certifications such as PMP or CISSP is typically required. Strong leadership, problem-solving abilities, and effective communication are essential soft skills for managing teams and projects. These skills are crucial for ensuring reliable IT operations, securing data, and aligning technology with business objectives.

What are some common challenges information systems managers face when balancing security needs with user accessibility?

Information Systems Managers often navigate the challenge of implementing robust security protocols while ensuring that users have seamless access to the systems and data they need. Striking this balance can involve managing access controls, monitoring for cyber threats, and maintaining compliance with regulations, all without impeding productivity. Effective communication with stakeholders and ongoing user training are essential to address these challenges, as is staying updated on emerging threats and security technologies. Collaborating closely with IT teams and business units helps create solutions that meet both security and operational needs.

What is the difference between Information Systems Manager vs Network Administrator?

AspectInformation Systems ManagerNetwork Administrator
CredentialsBachelor's degree in IT, Computer Science, or related field; often certifications like PMP, CISSPBachelor's degree in IT, Computer Science, or related field; certifications like Cisco CCNA, CompTIA Network+
Work EnvironmentOversees entire IT infrastructure, manages teams, strategic planningMaintains and supports network hardware/software, troubleshooting network issues
Employer & Industry UsageUsed across industries for IT leadership rolesCommon in organizations with complex network needs, including corporate and government sectors

While both roles require IT knowledge and certifications, the Information Systems Manager focuses on strategic management and overseeing IT systems, whereas the Network Administrator specializes in maintaining and troubleshooting network infrastructure. The roles often collaborate but differ in scope and responsibilities.

What is the average salary of an information systems manager?

The average salary of an information systems manager typically ranges from $90,000 to $150,000 annually, depending on experience, location, and industry. Professionals with certifications like PMP or CISSP and strong leadership skills tend to earn higher salaries.
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Information Systems Manager jobs near you
Infographic showing various Information Systems Manager job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 73% Full Time, 23% Part Time, and 3% Contract. Highlights an 93% Physical, 2% Hybrid, and 5% Remote job distribution, with an average salary of $105,783 per year, or $50.9 per hour.

Senior Manager, Information Systems

Gulf Coast Blood

Houston, TX • Hybrid

Full-time

Re-posted 8 days ago

Job description

Senior Manager, Information Systems

Join our team of heroes!

Are you seeking daily adventure while advancing your career? Look no further.

SCOPE OF RESPONSIBILITY

The Senior Manager – Information Systems is responsible for the strategy, governance, and performance of enterprise information systems supporting blood collection, laboratory testing, manufacturing, and distribution operations. This role ensures systems are reliable, compliant, and aligned with business objectives while enabling operational efficiency and patient safety in a regulated healthcare environment.

Just For You:

  • Free Parking!

  • Career advancement.

  • Engaging and exciting opportunity to support an organization that SAVES LIVES.

Tips to thrive in our culture:

  • Embody our Core Values of Commitment, Integrity, and Respect.

  • Work to actively create experiences that inspire others to save lives, each and every day.

  • Embrace doing it right, making connections, and creating desired experiences.

  • Comply with all organizational policies and standards, including safety rules, and be willing to report actual and potential violations to the appropriate supervisor or manager.

ESSENTIAL DUTIES AND RESPONSIBILITIES

Information Systems Leadership (35%)

  • Lead the strategy, implementation, and lifecycle management of enterprise information systems.

  • Oversee systems supporting critical operations, including:

    • Laboratory Information Systems (LIS)

    • Donor Management Systems

    • Manufacturing and Quality Systems

    • ERP and Supply Chain Applications

  • Ensure system reliability, scalability, and alignment with organizational priorities.

Application Governance & Optimization (25%)

  • Establish and maintain governance frameworks for system utilization, enhancements, and upgrades.

  • Partner with business stakeholders to continuously optimize workflows and system performance.

  • Prioritize and manage application roadmaps aligned with operational and clinical needs.

  • Ensure proper documentation, validation, and lifecycle management of systems.

Compliance & Regulatory Oversight (20%)

  • Ensure all systems meet compliance requirements including FDA, AABB, HIPAA, and GxP standards.

  • Support system validation, audit readiness, and regulatory inspections.

  • Maintain change control processes and documentation in alignment with quality standards.

Business Partnership & Stakeholder Engagement (10%)

  • Collaborate with clinical, laboratory, manufacturing, and administrative leaders to align systems with operational needs.

  • Serve as a trusted advisor for system capabilities, enhancements, and innovations.

  • Translate business requirements into technical solutions.

Team Leadership & Development (10%)

  • Lead and develop a team of analysts and application specialists.

  • Foster a culture of accountability, continuous learning, and service excellence.

  • Support workforce planning and succession development.

Required Qualifications:

Education:

  • Bachelor’s degree in Information Technology, Computer Science, Healthcare Informatics, or related field required.

  • Master’s degree preferred.

Experience:

  • 8–12+ years of experience in information systems, enterprise applications, or IT systems management.

  • 3–5+ years in leadership roles.

  • Experience in healthcare, life sciences, blood banking, or regulated manufacturing required.

  • Strong understanding of system validation, compliance, and regulatory environments.

  • Experience managing enterprise platforms such as LIS, ERP, or clinical systems.

Preferred Qualifications:

  • Experience with system integration and interoperability (HL7, APIs, middleware).

  • Familiarity with cloud-based enterprise systems and platforms.

  • ITIL or relevant certifications.

Working Conditions & Physical Demands:

  • Work Environment: Hybrid (in-office and remote).

  • Physical Requirements: Ability to sit or stand for extended periods.

  • Travel: Occasional travel for site visits or vendor meetings.

  • Schedule: Standard business hours with after-hours support as needed.

Who We Are:

Since 1975, Gulf Coast Blood has been one of the nation’s largest community blood centers, serving 170 hospitals across 26 counties. Headquartered in Houston, we support the world’s largest medical complex—the Texas Medical Center—while operating 18 donor centers and hosting more than 7,000 mobile blood drives each year. As an FDA-accredited nonprofit, we provide high-quality human cellular material for both scientific and therapeutic use.

Some Jobs Change Lives. Others Save Them. 

Think you have what it takes to save lives with us? We want to hear from you.


EQUAL OPPORTUNITY EMPLOYER STATEMENT

Gulf Coast Blood is an Equal Employment Opportunity Employer. Qualified applicants for positions are considered without regard to race/ethnicity, color, religion, national origin, age, pregnancy, sex, sexual orientation, gender identity, transgender status, military status, protected veteran status, disability status, genetic testing results, or any other basis or characteristic prohibited by applicable law, statute, regulation or Executive Order.