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End User Computing Jobs (NOW HIRING)

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Manager, End User Compute

San Antonio, TX · On-site

$97.20K/yr

In-depth knowledge of end user computing management, including expertise in provisioning, managing, and securing laptops and mobile devices, as well as supporting collaboration technologies such as ...

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How much do end user computing jobs pay per year?

As of May 31, 2026, the average yearly pay for end user computing in the United States is $107,638.00, according to ZipRecruiter salary data. Most workers in this role earn between $85,000.00 and $128,500.00 per year, depending on experience, location, and employer.

What is an End User Computing job?

An End User Computing (EUC) job focuses on managing and supporting the IT systems, devices, and applications that employees use daily. Professionals in this role ensure that desktops, laptops, mobile devices, and virtual environments run smoothly and securely. They handle troubleshooting, software deployment, system updates, and user support to enhance productivity. EUC specialists also work on endpoint security, automation, and cloud solutions to optimize the end-user experience.

What are the key skills and qualifications needed to thrive in the End User Computing position, and why are they important?

To excel in End User Computing, you typically need strong technical knowledge of desktop operating systems, hardware troubleshooting, software deployment, and IT support processes, usually supported by relevant IT certifications like CompTIA A+, Microsoft 365 or equivalent experience. Familiarity with endpoint management tools (such as Microsoft Endpoint Configuration Manager), Active Directory, virtualization, and remote support systems is crucial for the role. Excellent problem-solving skills, patience, and clear communication are key soft skills that help professionals deliver effective support to users. These skills and qualifications are essential for providing timely, efficient, and user-focused technology solutions in diverse business environments.

What are typical responsibilities in an End User Computing role?

In an End User Computing position, your daily tasks often include assisting users with hardware and software issues, managing device setups and configurations, installing security updates, and troubleshooting technical problems remotely or in person. You may also be responsible for supporting new technology rollouts, maintaining inventory of devices, and ensuring compliance with IT policies. Collaboration with IT teams, business units, and occasionally external vendors is common to provide seamless technology experiences for end users. This role is ideal for professionals who enjoy hands-on technical work and interacting with people to solve diverse IT challenges.
More about End User Computing jobs
What cities are hiring for End User Computing jobs? Cities with the most End User Computing job openings:
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End User Computing jobs near you
Infographic showing various End User Computing job openings in the United States as of May 2026, with employment types broken down into 2% Internship, 65% Full Time, 9% Part Time, 18% Temporary, 3% Contract, and 3% Nights. Highlights an 91% Physical, 3% Hybrid, and 6% Remote job distribution, with an average salary of $107,638 per year, or $51.7 per hour.

End User Computing Engineer

Definium Therapeutics

San Diego, CA • On-site, Remote

$100.93K - $123.38K/yr

Full-time

Medical, Dental, Vision, Retirement

Posted 4 days ago

Job description

Definium Therapeutics is a late-stage clinical biopharmaceutical company and our mission is to forge a new era of psychiatry by applying scientific rigor to psychedelics, with the goal of developing accessible treatments that unlock healing at scale.
Our lead product candidate, lysergide tartrate (our proprietary orally disintegrating tablet form of lysergide (LSD) D-tartrate), represents a highly differentiated, potential best-in-class opportunity for patients suffering from generalized anxiety, major depressive disorder, and posttraumatic stress disorder. Our early stage pipeline includes DT402, the R-enantiomer of MDMA and is under development to target the core symptoms of autism spectrum disorder (ASD), specifically addressing social communication challenges.
Guided by the recognition that patients deserve more than better, Definium is relentlessly advancing a new generation of therapeutics intended to address the underlying causes of psychiatric and neurological disorders. By turning evidence into impact, Definium aims to change the trajectory of today's mental health care crisis and enable a healthier future. Headquartered in New York, Definium Therapeutics trades on Nasdaq under the symbol DFTX.
Together we are moving psychiatry forward-beyond better, into a boundless future. Join us!
Reporting to the Sr. Director of Information Technology, the End-User Computing (EUC) Engineer will be responsible for providing primary operational support for end-user hardware and software for a fully remote and geographically distributed company with a growing physical presence in Raleigh/Durham, San Diego and Philadelphia. The prospective candidate will provide level 1 and 2 support for the enterprise and collaborate with senior members of IT on resolution of next-level support issues. The candidate will drive and participate in design, architecture, engineering, implementation, and operations of Definium global SaaS IT and business application portfolio to establish and maintain core operational, compliance, security, privacy, and other KPIs and standards. He/she will have a passion for problem solving, thrives in a diverse global organization, provides an excellent end-user experience, explores innovative technologies, and is driven to seek continuous improvement.
Responsibilities:
  • Provide operational support for remote staff. This will include hardware and software issues
  • Create, update, triage, and close support tickets in the Definium ITSM to ensure a thorough documentation of requests and incidents, end-user communication, root cause analysis and resolution
  • IT lead for all new and departing employee responsibilities. Ensure compliance with all on-boarding and off-boarding policies and procedures
  • Coordinate the hardware lifecycle for remote employees from procurement, configuration, collection, and retirement
  • Provide primary/secondary system administration to IT systems
  • Work closely with IT MSPs and professional service providers
  • Assist in identifying, evaluating, justifying, and deploying, new products, technologies, systems, services, and workflows
  • Independently perform actions under departmental change control procedures with minimal oversight or assistance
  • Ensure compliance for technology projects and processes including Sarbanes Oxley (SOX), 21 CFR Part 11, cGxP, and GDPR
  • Author and review standard operating procedures and knowledge-based articles for the maintenance and operation of software applications
  • Ensure that best practices for the service and support of technology products are documented and followed
  • Stay up to date on industry trends and best practices

Qualifications:
  • Minimum bachelor's degree or equivalent work experience
  • 2+ years of Tier I operational support experience, preferably within a regulated life sciences environment that has a remote or hybrid workforce
  • 2+ years supporting macOS and Windows laptops via MDM
  • 2+ years supporting Identity platforms [OKTA or Entra/AzureAD]
  • 2+ years supporting SaaS applications
  • Experience administering Co-Pilot, M365, SharePoint, Powershell, Cisco Umbrella, CrowdStrike, CheckPoint, M365, Slack, Zoom, DocuSign, FreshService, Intune, Kandji, Apple Business Manager, Adobe, and OKTA
  • Strong verbal and written communication skills
  • Excellent vendor management and negotiation skills
  • Strong remote triaging skills
  • Strong experience managing SharePoint sites and M365 permissions
  • SOX and/or 21 CFR Part 11 experience
  • Experience supporting multiple operating systems (Windows 11, iOS, and MacOS)
  • ITIL certification preferred

The starting base pay range for this position is $100,932.00 - 123,380.00. Compensation will be determined based on several factors including, but not limited to, skill set, years of experience, and the employee's geographic location.
Employees in this role may be entitled to additional compensation, including bonus and equity. Benefits information is listed on our Jobs Page. The Company provides competitive benefits to employees including:
  • 100% paid health benefits including Medical, Dental and Vision for you and your dependents
  • 401(k) program with company match and vesting after the turn of the first month after your start date
  • Flexible time off
  • Generous parental leave and some fun fringe perks!

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