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Manufacturing Systems Engineer Jobs (NOW HIRING)

bioMerieux

Manufacturing System Engineer

Lombard, IL · On-site

$104K - $129K/yr

Manufacturing Systems Engineer Position Summary The Manufacturing Systems Engineer is responsible for supporting and improving digital manufacturing systems used on the production floor. This role ...

Amgen

Senior Manufacturing Systems Engineer

Holly Springs, NC · On-site

$90K - $123K/yr

Senior Manufacturing Systems Engineer What you will do Let's do this. Let's change the world. In this vital role you will be part of Amgen's most technologically advanced drug substance manufacturing ...

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Manufacturing Systems Engineer information

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$40.5K

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$158.5K

How much do manufacturing systems engineer jobs pay per year?

As of Sep 1, 2026, the average yearly pay for manufacturing systems engineer in the United States is $110,216.00, according to ZipRecruiter salary data. Most workers in this role earn between $85,000.00 and $142,500.00 per year, depending on experience, location, and employer.

What is a manufacturing systems engineer?

Manufacturing Systems Engineers are professionals who design, implement, and optimize integrated systems used in manufacturing processes. They work to improve efficiency, quality, and productivity by analyzing workflows, selecting appropriate technologies, and ensuring systems work seamlessly together. Their role often involves coordinating between different departments, troubleshooting system issues, and implementing automation or process improvements. They play a key part in modernizing manufacturing operations and ensuring products are made efficiently and to high standards.

What are the key skills and qualifications needed to thrive as a manufacturing systems engineer?

To thrive as a Manufacturing Systems Engineer, you need a solid background in industrial or manufacturing engineering, process optimization, and analytical problem-solving, usually backed by a relevant engineering degree. Familiarity with CAD software, ERP systems, automation tools, and certifications like Six Sigma or Lean Manufacturing are typically required. Strong project management, communication, and teamwork skills help you collaborate across departments and drive continuous improvement initiatives. These competencies are crucial for optimizing production efficiency, ensuring product quality, and supporting the overall success of manufacturing operations.

What are some common challenges faced by manufacturing systems engineers when integrating new technologies into existing production lines?

Manufacturing Systems Engineers often encounter challenges such as ensuring compatibility between new technologies and legacy equipment, minimizing production downtime during upgrades, and training staff to effectively use new systems. They must carefully plan and coordinate with cross-functional teams—including production, IT, and quality assurance—to address potential disruptions and maintain product quality. Effective communication and thorough testing are key to a smooth integration process.

What is the difference between Manufacturing Systems Engineer vs Manufacturing Process Engineer?

AspectManufacturing Systems EngineerManufacturing Process Engineer
Primary FocusDesign, optimize, and integrate manufacturing systems and automationDevelop and improve manufacturing processes and workflows
Skills & CertificationsSystems engineering, automation, PLC programming, CADProcess analysis, Lean, Six Sigma, CAD
Work EnvironmentManufacturing plants, automation labsProduction lines, process development areas
Industry UsageManufacturing, automation, industrial engineeringManufacturing, process improvement, quality control

While both roles support manufacturing efficiency, Manufacturing Systems Engineers focus on integrating and automating entire systems, whereas Manufacturing Process Engineers concentrate on refining specific production processes. Understanding these distinctions helps in choosing the right career path or job search focus.

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Manufacturing Systems Engineer jobs near you
Infographic showing various Manufacturing Systems Engineer job openings in the United States as of August 2026, with employment types broken down into 95% Full Time, and 5% Contract. Highlights an 100% In-person job distribution, with an average salary of $110,216 per year, or $53 per hour.

Manufacturing System Engineer

BioFire Diagnostics

Lombard, IL

$104K - $129K/yr

Full-time

Medical, Dental, Vision, Life, Retirement

Re-posted 5 days ago

Job description

Manufacturing Systems Engineer

Position Summary

The Manufacturing Systems Engineer is responsible for supporting and improving digital manufacturing systems used on the production floor. This role focuses on the day-to-day ownership, support, and continuous improvement of the Tulip Manufacturing Execution System (MES) to ensure manufacturing operations are efficient, reliable, and compliant.

Working closely with Operations, Quality, Engineering, Maintenance, and IT, this position helps enable digital workflows, electronic records, and real-time shop-floor data in a fast-paced manufacturing environment.

Key Responsibilities

  • Develop, configure, test, and maintain Tulip MES applications that support manufacturing execution and electronic manufacturing records
  • Build and improve digital workflows, operator interfaces, forms, and dashboards
  • Partner with Operations and Engineering to convert manual or paper-based processes into digital solutions
  • Provide daily system support, troubleshooting, and issue resolution for manufacturing users
  • Monitor system performance and address recurring issues to improve reliability and usability
  • Support system updates, testing, releases, and user acceptance activities
  • Maintain system documentation, configurations, and support materials
  • Ensure digital manufacturing systems meet GMP, quality, and regulatory requirements
  • Support change control, validation, testing documentation, and audit readiness
  • Collaborate with Quality and Validation teams to ensure compliant and sustainable system use
  • Assist with basic equipment connectivity and data flow troubleshooting
  • Support production needs in a multi-shift manufacturing environment, including occasional off-hours support

Qualifications

Required

  • Bachelor's degree in Electrical Engineering, Automation Technology, Industrial Technology, Mechatronics, or a related technical field
  • 2+ years of experience supporting automation, manufacturing systems, controls, or related engineering roles in a regulated manufacturing environment

Preferred

  • Experience with Manufacturing Execution Systems (MES) or digital manufacturing tools
  • Familiarity with PLC, HMI, and shop-floor system integration
  • Experience working in GMP-regulated industries (medical devices, pharmaceuticals, biotechnology, food & beverage)

Knowledge, Skills & Abilities

  • Strong troubleshooting and problem-solving skills
  • Ability to work cross-functionally with manufacturing and technical teams
  • Comfort working in a fast-paced production environment
  • Strong documentation and communication skills
  • Working knowledge of digital manufacturing systems and data-driven processes
  • Proficiency with standard computer tools (Outlook, Teams, Word, Excel)

Working Conditions

  • Combination of office and manufacturing floor environment
  • Ability to sit or stand for extended periods
  • Ability to wear required PPE
  • Ability to support operations during off-shift hours when needed
The estimated salary range for this role is between $104,700-129,700. This role is eligible to receive a variable annual bonus based on company, team, and individual performance per bioMerieux's bonus program. This range may differ from ranges offered for similar positions elsewhere in the country given differences in cost of living. Actual compensation within this range is determined based on the successful candidate's experience and will be presented in writing at the time of the offer.
In addition, bioMerieux offers a competitive Total Rewards package that may include:
A choice of medical (including prescription), dental, and vision plans providing nationwide coverage and telemedicine options
Company-Provided Life and Accidental Death Insurance
Short and Long-Term Disability Insurance
Retirement Plan including a generous non-discretionary employer contribution and employer match.
Adoption Assistance
Wellness Programs
Employee Assistance Program
Commuter Benefits
Various voluntary benefit offerings
Discount programs
Parental leaves
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