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99 Amgen Manufacturing Systems Engineer Jobs Hiring Near You

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Amgen Jobs Information

What is it like to work at Amgen?

Amgen is a biotechnology company that values innovation, collaboration, and patient-centricity, fostering a culture that encourages open communication and teamwork among its employees. The company's research and development teams work in a dynamic environment, often in collaboration with external partners and academia, to develop and deliver life-changing medicines to patients with serious diseases. Working at Amgen may appeal to candidates who are passionate about advancing medical science and improving human health, as the company offers opportunities for professional growth, mentorship, and contributions to groundbreaking research.

What makes Amgen an attractive place to work?

Amgen is a leading biotechnology company that has been at the forefront of innovation in the pharmaceutical industry for decades, with a strong focus on developing life-changing medicines for patients with serious diseases. The company's work environment is characterized by a culture of collaboration, innovation, and scientific excellence, with opportunities for employees to work on cutting-edge projects and contribute to groundbreaking research. As a result, Amgen offers a dynamic and challenging work environment that can provide employees with opportunities for professional growth, development, and impact in the field of biotechnology.
What other companies are hiring for Manufacturing Systems Engineer jobs?
Infographic showing various Manufacturing Systems Engineer job openings at Amgen in the United States as of July 2026, with employment types broken down into 100% Full Time. Highlights an 91% Physical, 1% Hybrid, and 8% Remote job distribution.
Manufacturing Systems Engineer

Manufacturing Systems Engineer

Amgen

Holly Springs, NC • On-site

Full-time

Medical, Dental, Vision, Life, Retirement

Posted 20 days ago


Job description

Career CategoryInformation SystemsJob Description

Join Amgen's Mission of Serving Patients

At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do.

Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Manufacturing Systems Engineer

What you will do

Let's do this. Let's change the world. In this vital role, you will be accountable for developing and continuously aligning the site manufacturing data ecosystem with rapidly changing business needs and Amgen Technology technical roadmaps. We are seeking candidates who possess expertise in business, and automation systems, information/data management and technical experience in database and data historian technologies and integration tools.

You will support the design, implementation, operation, and continuous improvement of manufacturing automation and information systems across the site. You will partner closely with manufacturing, quality, engineering, cybersecurity, and enterprise platform teams to ensure systems are reliable, compliant, and aligned with Amgen technology roadmaps.

This position may be filled at multiple experience levels, with scope and ownership aligned to demonstrated capability.

Responsibilities:

  • Support and/or lead the design, deployment, and lifecycle management of manufacturing automation and information systems: Delta V, FactoryTalk / Rockwell platforms, Building Automation Systems (BAS), ThinManager and mobile solutions, and Siemens Location tracking and/or related site services.
  • Provide technical support to manufacturing operations, including troubleshooting, system performance improvements, and incident response.
  • Participate in capital project execution, including requirements definition, design reviews, testing, validation, and startup support.
  • Own or contribute to system roadmaps, lifecycle planning, and technical debt reduction.
  • Collaborate with business partners to translate operational needs into functional and technical designs.
  • Support manufacturing data integrations, historians, reporting, and analytics solutions.
  • Ensure systems meet GMP, data integrity, cybersecurity, and validation requirements.
  • Manage vendor relationships and coordinate work with internal platform and service owners.
  • Support and/or lead Global Asset Lifecycle Management (GLAM) initiatives, including platform lifecycle planning, implementation, sustainment, and continuous improvement
  • Identify opportunities to simplify processes, eliminate inefficiencies, and automate manual workflows.
  • Stay current with industry and technology trends and apply learnings pragmatically to site operations.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The professional we seek is an individual with these qualifications.

Basic Qualifications:

Master's degree

OR

Bachelor's degree and 2 years of Information Systems, Engineering and/or Information Technology experience

OR

Associate's degree and 6 years of Information Systems, Engineering and/or Information Technology experience

OR

High school diploma / GED and 8 years of Information Systems, Engineering and/or Information Technology experience

Preferred Qualifications:

  • Experience supporting manufacturing automation and information systems in a regulated manufacturing environment, preferably within pharmaceutical or biotechnology industries.
  • Hands-on experience with one or more automation or site systems platforms, such as DeltaV, Rockwell FactoryTalk, Building Automation Systems (BAS), ThinManager, Siemens location tracking, or related manufacturing platforms.
  • Working knowledge of information systems infrastructure fundamentals, including Windows-based systems, virtualization, networking, storage, and Active Directory.
  • Experience supporting or implementing manufacturing data integrations, historians, reporting, or analytics solutions (e.g., SQL, web services, data mapping).
  • Familiarity with GMP software development lifecycle, change control, validation practices, and regulated system support.
  • Experience working with capital projects or complex system implementations, including design reviews, testing, and deployment.
  • Ability to translate business and operational requirements into functional and technical solutions.
  • Experience managing multiple priorities and contributing effectively in a fast-paced manufacturing environment.
  • Strong communication skills and the ability to collaborate with both technical and non-technical stakeholders.
  • Experience working with vendors and cross-functional teams to deliver and sustain technology solutions.
  • Exposure to Agile or iterative delivery methodologies is a plus.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

  • A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans
  • Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

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Salary Range

105,362.60USD -142,549.40USD