Laboratory information system (LIS) jobs involve handling administration and troubleshooting duties for a software system that records, organizes, and stores data from a clinical laboratory. As a LIS specialist or administrator, you install, configure, and manage the laboratory software. Your responsibilities include ensuring that you complete regular system backups, software updates, and data security audits. Some positions involve data entry tasks, such as uploading the results of lab tests. Some LIS specialists or information systems managers train other employees in the use of the system. You can find this job at a large healthcare facility or with an independent clinical lab.