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Laboratory Information System Jobs (NOW HIRING)

JOB SUMMARY The Laboratory Information Systems (LIS) Manager is responsible for the strategic ... Ensure system reliability, performance, availability, security, and scalability across laboratory ...

$100 - $125/hr

Laboratory Information Systems (LIS) Administrator Location: 50 Eastdale Avenue North Poughkeepsie ... Monitor system performance and proactively identify opportunities for process improvement.

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Laboratory Information System information

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$32.5K

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How much do laboratory information system jobs pay per year?

As of Sep 1, 2026, the average yearly pay for laboratory information system in the United States is $91,960.00, according to ZipRecruiter salary data. Most workers in this role earn between $70,000.00 and $111,000.00 per year, depending on experience, location, and employer.

What is a laboratory information system?

A Laboratory Information System (LIS) is specialized software designed to manage and streamline the operations of a laboratory. It handles functions such as sample tracking, test ordering, results management, workflow automation, and data reporting. LIS enhances efficiency, accuracy, and compliance by integrating with laboratory instruments and other healthcare systems. It is widely used in clinical, research, and industrial labs to support daily operations and regulatory requirements.

What jobs work with a laboratory information system?

Laboratory information system (LIS) jobs involve handling administration and troubleshooting duties for a software system that records, organizes, and stores data from a clinical laboratory. As a LIS specialist or administrator, you install, configure, and manage the laboratory software. Your responsibilities include ensuring that you complete regular system backups, software updates, and data security audits. Some positions involve data entry tasks, such as uploading the results of lab tests. Some LIS specialists or information systems managers train other employees in the use of the system. You can find this job at a large healthcare facility or with an independent clinical lab.

What are the key skills and qualifications needed to thrive as a laboratory information system specialist, and why are they important?

To thrive as a Laboratory Information System (LIS) Specialist, you need a background in laboratory sciences or IT, experience with clinical workflows, and often a degree in medical technology, computer science, or a related field. Familiarity with major LIS platforms (such as Cerner, Epic Beaker, or Sunquest), HL7 interface standards, and relevant certifications like ASCP or LIS-specific credentials are typically required. Strong problem-solving ability, attention to detail, and effective communication skills help you collaborate with laboratory staff and IT teams. These competencies ensure accurate data management, regulatory compliance, and smooth laboratory operations essential to healthcare delivery.

What are some common challenges faced by laboratory information system specialists and how can they be addressed?

LIS specialists often encounter challenges such as integrating new technologies with legacy systems, maintaining data accuracy, and ensuring compliance with healthcare regulations. Working closely with laboratory staff and IT teams is crucial for successful troubleshooting and workflow optimization. Continuous training and staying updated on industry standards help LIS specialists anticipate issues and implement effective solutions, making them valuable contributors to both laboratory efficiency and patient care.

What is the difference between Laboratory Information System vs Laboratory Technician?

AspectLaboratory Information SystemLaboratory Technician
CredentialsTypically requires a degree in health informatics, computer science, or related fieldHigh school diploma or associate degree in laboratory technology
Work EnvironmentSoftware systems in labs, hospitals, or clinicsLaboratory settings performing tests and sample analysis
Employer & IndustryHealthcare, clinical labs, research institutionsMedical laboratories, hospitals, diagnostic centers
Primary FocusManaging lab data, software implementation, and system maintenancePerforming laboratory tests and preparing samples

The Laboratory Information System (LIS) focuses on managing laboratory data and software operations, while the Laboratory Technician handles sample testing and analysis. Both roles are essential in healthcare labs but serve different functions within the laboratory environment.

What cities are hiring for Laboratory Information System jobs?

Cities with the most Laboratory Information System job openings:

What are the most commonly searched types of Laboratory Information System jobs?

The most popular types of Laboratory Information System jobs are:

What states have the most Laboratory Information System jobs?

States with the most job openings for Laboratory Information System jobs include:

Infographic showing various Laboratory Information System job openings in the United States as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $91,960 per year, or $44.2 per hour.

Laboratory Information System Analyst/Administrator

Bethesda, MD • On-site


Guidehouse
Business Management Consulting • 10K+ employees

8.0

Company rating: 8.0 out of 10

Based on 28 frontline employees who took The Breakroom Quiz

35th of 72 rated business consultants

People enjoy working here

Good employer

Paid breaks


$85K - $141K/yr

Full-time

Medical, Dental, Vision, Life, Retirement

Posted 19 days ago


Job description

Job Family:
Medical Technologist
Travel Required:
None
Clearance Required:
Ability to Obtain Public Trust
What You Will Do:
Job Posting
We are currently searching for a Clinical Laboratory Scientist (CLS) with Super User, Analyst, or Administrator-level experience working with a clinical hospital laboratory information system (LIS) to provide support to the National Institutes of Health (NIH) in Bethesda, MD. This is a day shift position Monday through Friday with on-call rotations to cover evenings, nights, weekends, and holidays. The individual may also be required to work non-routine shifts to accommodate special LIS/IT projects.
What You Will Do:
Modify and maintain Laboratory Information System (LIS) software as assigned by the Laboratory Information Manager, including:
  • Create new tests and modify existing tests as required.
  • Test and implement system modifications and enhancements.
  • Assist with organization and validation of mapping structure for all tests in LIS.
  • Troubleshoot any identified LIS issues as assigned.
  • Make security changes for employees.

Interact with all LIS/CRIS users and members of other CC departments. including:
  • Identify computer problems and communicate them to IT personnel when
  • necessary.
  • Identify and resolve problems with LIS access through Citrix.
  • Assist in incorporating LIS competency into laboratory Staff operations.
  • Communicate with the LIS vendor to enter tasks as directed.

Assist with the coordination and implementation of CRIS upgrades/updates, including:
  • Collect and validate CRIS requests from each laboratory service.
  • Compiles CRIS change requests and submits to DCRI.
  • Coordinates the testing of CRIS changes in all available LIS environments.

Work with reference lab interfaces related to the LIS, including:
  • Monitor reference laboratory interfaces as appropriate.
  • Troubleshoot communication problems.
  • Build, validate, and test all new test requests and any modifications to interfaces to ensure the interface integrity.
  • Assist with validation of all new interface projects (e.g. Mayo Access).
  • Schedule Master Test Guide (website) changes.
  • Coordinate lab test changes with Chief Techs, Senior Staff, and LAN Administrator to update the laboratory website.

Identify problems that may adversely affect test performance or reporting of test results; correct the problem or notify senior staff; document all corrective actions taken.
What You Will Need:
What You Will Need:
  • Bachelor's degree plus a minimum of four (4) years full-time specialized clinical laboratory experience working in a clinical hospital laboratory.
  • Successful completion of a Medical Laboratory Scientist/Clinical Laboratory Scientist program accredited by the National Accrediting Agency for Clinical Laboratory Sciences (NAACLS) or an accrediting body recognized by the U.S. Department of Education at the time the degree was obtained.
  • Minimum TWO (2) years full-time experience working with a clinical hospital laboratory information system at a Super User, Analyst, or Administrator level. This LIS experience may be included in the minimum of four (4) years of full-time specialized clinical laboratory experience.
  • Must be able to obtain and maintain a Federal or DoD "public trust"; candidates must receive approved adjudication prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred

What Would Be Nice To Have:
  • Preferred fields of study: Biological Science, Chemistry, Mathematics, Medical Laboratory Science, or a related discipline.
  • Strong communications skills, written and spoken.
  • Experience/knowledge as a Clinical Laboratory Scientist Generalist is preferred.
  • SCC SOFT laboratory information system (LIS) experience is preferred.
  • Ability to lift 10 - 30 pounds.
  • Excellent hand-eye coordination.
  • Excellent analytical, organizational and time management skills.

The annual salary range for this position is $85,000.00-$141,000.00. Compensation decisions depend on a wide range of factors, including but not limited to skill sets, experience and training, security clearances, licensure and certifications, and other business and organizational needs.
What We Offer:
Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.
Benefits include:
  • Medical, Rx, Dental & Vision Insurance
  • Personal and Family Sick Time & Company Paid Holidays
  • Parental Leave
  • 401(k) Retirement Plan
  • Group Term Life and Travel Assistance
  • Voluntary Life and AD&D Insurance
  • Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts
  • Transit and Parking Commuter Benefits
  • Short-Term & Long-Term Disability
  • Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities
  • Employee Referral Program
  • Corporate Sponsored Events & Community Outreach
  • Care.com annual membership
  • Employee Assistance Program
  • Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)
  • Position may be eligible for a discretionary variable incentive bonus

About Guidehouse
Guidehouse is an Equal Opportunity Employer-Protected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation.
Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.
If you have visited our website for information about employment opportunities, or to apply for a position, and you require an accommodation, please contact Guidehouse Recruiting at 1-571-633-1711 or via email at RecruitingAccommodation@guidehouse.com. All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation.
All communication regarding recruitment for a Guidehouse position will be sent from Guidehouse email domains including @guidehouse.com or guidehouse@myworkday.com. Correspondence received by an applicant from any other domain should be considered unauthorized and will not be honored by Guidehouse. Note that Guidehouse will never charge a fee or require a money transfer at any stage of the recruitment process and does not collect fees from educational institutions for participation in a recruitment event. Never provide your banking information to a third party purporting to need that information to proceed in the hiring process.
If any person or organization demands money related to a job opportunity with Guidehouse, please report the matter to Guidehouse's Ethics Hotline. If you want to check the validity of correspondence you have received, please contact recruiting@guidehouse.com. Guidehouse is not responsible for losses incurred (monetary or otherwise) from an applicant's dealings with unauthorized third parties.
Guidehouse does not accept unsolicited resumes through or from search firms or staffing agencies. All unsolicited resumes will be considered the property of Guidehouse and Guidehouse will not be obligated to pay a placement fee.


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