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How much do laboratory information system jobs pay per year?

As of Aug 11, 2026, the average yearly pay for laboratory information system in the United States is $91,960.00, according to ZipRecruiter salary data. Most workers in this role earn between $70,000.00 and $111,000.00 per year, depending on experience, location, and employer.

What is a laboratory information system?

A Laboratory Information System (LIS) is specialized software designed to manage and streamline the operations of a laboratory. It handles functions such as sample tracking, test ordering, results management, workflow automation, and data reporting. LIS enhances efficiency, accuracy, and compliance by integrating with laboratory instruments and other healthcare systems. It is widely used in clinical, research, and industrial labs to support daily operations and regulatory requirements.

What are some common challenges faced by laboratory information system specialists and how can they be addressed?

LIS specialists often encounter challenges such as integrating new technologies with legacy systems, maintaining data accuracy, and ensuring compliance with healthcare regulations. Working closely with laboratory staff and IT teams is crucial for successful troubleshooting and workflow optimization. Continuous training and staying updated on industry standards help LIS specialists anticipate issues and implement effective solutions, making them valuable contributors to both laboratory efficiency and patient care.

What is the difference between Laboratory Information System vs Laboratory Technician?

AspectLaboratory Information SystemLaboratory Technician
CredentialsTypically requires a degree in health informatics, computer science, or related fieldHigh school diploma or associate degree in laboratory technology
Work EnvironmentSoftware systems in labs, hospitals, or clinicsLaboratory settings performing tests and sample analysis
Employer & IndustryHealthcare, clinical labs, research institutionsMedical laboratories, hospitals, diagnostic centers
Primary FocusManaging lab data, software implementation, and system maintenancePerforming laboratory tests and preparing samples

The Laboratory Information System (LIS) focuses on managing laboratory data and software operations, while the Laboratory Technician handles sample testing and analysis. Both roles are essential in healthcare labs but serve different functions within the laboratory environment.

What are the key skills and qualifications needed to thrive as a laboratory information system specialist, and why are they important?

To thrive as a Laboratory Information System (LIS) Specialist, you need a background in laboratory sciences or IT, experience with clinical workflows, and often a degree in medical technology, computer science, or a related field. Familiarity with major LIS platforms (such as Cerner, Epic Beaker, or Sunquest), HL7 interface standards, and relevant certifications like ASCP or LIS-specific credentials are typically required. Strong problem-solving ability, attention to detail, and effective communication skills help you collaborate with laboratory staff and IT teams. These competencies ensure accurate data management, regulatory compliance, and smooth laboratory operations essential to healthcare delivery.

What jobs work with a laboratory information system?

Laboratory information system (LIS) jobs involve handling administration and troubleshooting duties for a software system that records, organizes, and stores data from a clinical laboratory. As a LIS specialist or administrator, you install, configure, and manage the laboratory software. Your responsibilities include ensuring that you complete regular system backups, software updates, and data security audits. Some positions involve data entry tasks, such as uploading the results of lab tests. Some LIS specialists or information systems managers train other employees in the use of the system. You can find this job at a large healthcare facility or with an independent clinical lab.

More about Laboratory Information System jobs
What cities are hiring for Laboratory Information System jobs? Cities with the most Laboratory Information System job openings:
What are the most commonly searched types of Laboratory Information System jobs? The most popular types of Laboratory Information System jobs are:
What states have the most Laboratory Information System jobs? States with the most job openings for Laboratory Information System jobs include:
What job categories do people searching Laboratory Information System jobs look for? The top searched job categories for Laboratory Information System jobs are:
Laboratory Information System jobs near you
Infographic showing various Laboratory Information System job openings in the United States as of August 2026, with employment types broken down into 84% Full Time, 8% Part Time, and 8% Contract. Highlights an 100% In-person job distribution, with an average salary of $91,960 per year, or $44.2 per hour.

Laboratory IT Associate

Prism Biotech

King Of Prussia, PA • On-site

Full-time

Re-posted 17 days ago

Job description

This role will serve as a business representative for laboratory IT systems and will be responsible for mentoring laboratory personnel on the use of electronic lab systems as well as supporting internal and external audits as a laboratory IT system subject matter expert.
Key Objectives/Deliverables:
  • Performs or supports Laboratory with the validation of laboratory equipment and software systems.
  • Supports the establishment and maintenance of the validated state of software-based computerized systems in use in the laboratory.
  • Act as business owner and contact SME for QC laboratory IT systems.
  • Responsible for collecting data and authoring periodic review documents for laboratory information systems.
  • Provide oversight and support continuous improvement of quality systems as they relate to laboratory informatics.
  • Apply knowledge of quality principles, cGMP, and laboratory systems towards the development and execution of local procedures, training courses, and practices.
  • Assist in improvement of quality systems by creating or revising worksheets, developing, or updating laboratory execution system documentation, updating laboratory methods, and maintaining other lab documentation systems.
  • Responsible for method management in the QC Laboratory, specific to scripted or coded methods.
  • Supports and/or leads investigations, CAPA and change control initiatives.
  • Responsible for maintaining a safe work environment, working safely and accountable for supporting all HSE Corporate and Site Goals.
  • Ability to work in a lab environment including wearing appropriate PPE and other safety related equipment or considerations.
Requirements (Education, Experience, Training):
  • Bachelor’s degree in a computer science, life science, or applied science with at least five (5) years of demonstrated relevant experience in a GMP lab.
Preferred attributes but not required:
  • Experience with computer systems including Microsoft Office suite, laboratory information management systems.
  • Investigation and deviation management experience.
  • Demonstrated proficiency in computer system validation.
  • Experience with compliance requirements and regulatory expectations.
  • Demonstrated accuracy and proficiency in analytical skills.
  • Strong oral and written communication skills and demonstrated through documentation and presentation skills.
  • Demonstrated strong interpersonal interaction skills.

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