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The Principal Statistical Programmer will lead programming activities for one or more studies, ensuring high-quality development, validation, and delivery of complex analysis outputs. Drive technical excellence, innovation, and standards adoption while providing strategic insights into study data. Mentor junior programmers and influence programming approaches through strong technical leadership and communication.
This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:
Technical Leadership & Delivery

• Lead programming for studies, ensuring efficient development and validation of analysis packages.
• Select appropriate tools/languages and solve complex technical challenges.
• Identify and implement improvements, including use of AI/ML.
• Contribute to departmental initiatives and technical strategy.

Quality & Compliance

• Ensure adherence to standards (e.g., GPP, CDISC) and regulatory requirements.
• Perform QC on critical outputs and technical documents (e.g., cSDRG, ADRG).
• Maintain governance and oversee TMF compliance.

Strategy & Innovation

• Drive adoption of modern technologies, standards, and Agile practices.
• Provide technical input on programming strategies and study design.
• Act as SME for emerging tools when needed.

Communication & Mentorship

• Communicate technical concepts, risks, and timelines clearly to stakeholders.
• Mentor junior programmers and share best practices internally and externally.

Collaboration & Execution

• Support sprint planning and project delivery across studies.
• Collaborate cross-functionally and manage data access appropriately.
• Support regulatory interactions and contribute to CoE activities.

Accountabilities

• Serve as Lead Programmer for complex or multiple studies.
• Ensure quality, compliance, and efficient execution of programming activities.
• Make data-driven decisions and proactively address risks and issues.

Why You:
Basic Qualification
We are seeking professionals with the following required skills and qualifications to help us achieve our goals:

• Bachelor's degree in Statistics, Computer Science, or a related field.
• Expertise in R programming.
• 6+ years of clinical programing experience
• 5+ years of experience in the Pharmaceutical or Biotechnology industry.
• Experience using generative AI tools and coding assistants (e.g., GitHub Copilot, Codex, and Claude) to improve programming efficiency, automation, code quality, and analytical workflows in clinical programming.

Preferred Qualification
If you have the following characteristics, it would be a plus:

• Strong experience supporting HIV clinical trials and drug development within the pharmaceutical or biotechnology industry.
• Advanced degree in Statistics, Computer Science, Data Science, or a related discipline.
• Experience using generative AI tools and coding assistants (e.g., GitHub Copilot, Claude, or Codex) to improve programming productivity and automation.
• Familiarity with modern software engineering practices, including Git-based workflows, reusable frameworks, and automation pipelines.
• Experience with R, Python, and open-source analytics tools within regulated clinical development environments.
• Experience contributing to standards development, process improvement, or digital transformation initiatives.
• Knowledge of Agile delivery methodologies and collaborative product development approaches.
• Demonstrated experience leading programming activities for complex clinical studies or multiple projects.
• Strong understanding of CDISC standards, regulatory expectations, and quality/compliance requirements.
• Excellent analytical, problem-solving, communication, and stakeholder management skills.
• Experience mentoring or guiding junior team members

At ViiV Healthcare, our mission is to ensure that the impact of HIV is minimized for individuals and communities worldwide. We are deeply committed to:

• Patient Focus - Always putting the needs of those living with HIV first.
• Transparency, Respect, and Integrity - Maintaining open communication, mutual respect, and a high ethical standard in everything we do.
• Courage and Accountability - Demonstrating bold leadership by making agile, evidence-based decisions and taking responsibility for outcomes.
• Development and Teamwork - Investing in our team members' growth and building collaborative, impact-driven partnerships internally and externally.

As part of our 30-year legacy of improving lives with HIV, ViiV Healthcare is not just a place to work-it is a community where every team member is empowered to bring their very best to the fight against HIV/AIDS. Our holistic approach extends beyond medicine to supporting sustainable community programs and improving access to care.
#LI-ViiV
#LI-GSK
Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program ViiV offers US employees. All ViiV employees receive the same benefits options and plans as GSK employee.
Why Us?
At ViiV Healthcare, we will not rest until we leave no person living with HIV behind. Until the 40 million people living with HIV is down to zero, we will continue searching for new ways to limit the impact of HIV.
We are the only pharmaceutical company solely focused on combating, preventing, and ultimately eradicating HIV and AIDS. At ViiV Healthcare, we do things differently. Born out of a partnership between GSK and Pfizer in 2009, with Shionogi joining in 2012, we are determined to help end the HIV epidemic. We are guided by our mission to leave no person living with HIV behind and it is this mission that unites our employees located across the globe. We combine expertise in research, manufacturing, policy and more to push the boundaries of what people think is possible in HIV treatment and care. As a result of our connection with GSK, we are able to draw on their proud history and resources. This means that you would receive all the employee benefits offered by GSK.
Living our mission of leaving no person living with HIV behind means keeping inclusion and diversity at the heart of everything we do - from our breakthrough innovation, to our diverse portfolio of medicines as well as the work we do to partner with HIV communities.
Having a truly inclusive culture where we're all able to be ourselves and feel like we belong will make us an even stronger team, better able to perform as a business and deliver on our mission to leave no person living with HIV behind.
If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at - usrecruitment.adjustments@gsk.com
ViiV is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.
Important notice to Employment businesses/ Agencies
ViiV does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact ViiV's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to ViiV. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and ViiV. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of ViiV. ViiV shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, ViiV may be required to capture and report expenses ViiV incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure ViiV's compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/