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Vice President Of It Operations Jobs (NOW HIRING)

Clemens Food Group

Vice President of IT & IS

Hatfield, PA · On-site

$158K - $198K/yr

Clemens Food Group is looking for a Vice President of IT & Information Systems to shape the future of our technology landscape, driving innovation, scalability, and business alignment across the ...

Mondo

VP of IT

Northfield, VT · On-site

$250K - $300K/yr

Vice President of Information Technology, location is Onsite. The start date is ASAP for this ... Partner with Operations, Manufacturing, Supply Chain, Sales, Finance, HR, and executive leadership ...

Joyce/Dayton

Vice President of Technology

Kettering, OH

$139K - $175K/yr

Job Title Vice President of Technology Summary The Vice President of Technology is accountable for all information technology infrastructure and operations - including support, hardware, software ...

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Vice President Of It Operations information

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$68.5K

$155.8K

$264K

How much do vice president of it operations jobs pay per year?

As of Aug 18, 2026, the average yearly pay for vice president of it operations in the United States is $155,780.00, according to ZipRecruiter salary data. Most workers in this role earn between $115,500.00 and $185,000.00 per year, depending on experience, location, and employer.

What is a vice president of IT operations?

Vice Presidents of IT Operations are senior executives responsible for overseeing an organization’s information technology strategy, infrastructure, and daily operations. They lead teams that manage IT systems, networks, cybersecurity, and technical support, ensuring technology aligns with business objectives. Their role often includes budgeting, policy development, vendor management, and guiding digital transformation initiatives. VPs of IT Operations collaborate with other executives to drive innovation, improve efficiency, and maintain system reliability across the company.

What are the key skills and qualifications needed to thrive as a vice president of IT operations?

To thrive as a Vice President of IT Operations, you need extensive experience in IT management, strategic planning, and a solid understanding of infrastructure, typically supported by a bachelor’s or master’s degree in computer science or a related field. Familiarity with ITIL frameworks, enterprise resource planning (ERP) systems, and certifications like PMP or CISSP are highly valuable. Exceptional leadership, decision-making, and communication skills set top candidates apart in this executive role. These competencies ensure effective alignment between IT initiatives and business objectives, driving operational excellence and organizational growth.

What are the main challenges a vice president of IT operations typically faces when aligning IT strategy with overall business objectives?

A Vice President of IT Operations often encounters the challenge of ensuring that IT initiatives directly support the company’s broader business goals. This requires close collaboration with executive leadership to understand business priorities, translating them into actionable IT projects, and managing resource constraints. Balancing day-to-day operational stability with long-term innovation can be demanding, as can keeping up with technology trends and cybersecurity risks. Effective communication, strategic planning, and the ability to lead cross-functional teams are essential for overcoming these challenges.

What is the difference between Vice President Of It Operations vs Director Of IT Operations?

AspectVice President Of It OperationsDirector Of IT Operations
ResponsibilitiesStrategic planning, executive decision-making, overseeing multiple departmentsManaging daily IT operations, implementing policies, team supervision
CredentialsTypically requires extensive experience, often a bachelor's or master's degree in IT or related fields, with leadership certificationsUsually requires a bachelor's degree in IT or related fields, with relevant technical certifications
Work EnvironmentExecutive offices, strategic meetings, high-level planningIT departments, operational settings, project management
Industry UsageCommonly used in large organizations and corporationsUsed across various organizations, especially mid-sized to large companies

The Vice President Of It Operations focuses on strategic leadership and high-level decision-making, while the Director Of IT Operations handles daily management and operational tasks. Both roles require strong IT knowledge, but the VP role emphasizes executive oversight and long-term planning.

What cities are hiring for Vice President Of It Operations jobs?

Cities with the most Vice President Of It Operations job openings:

What are the most commonly searched types of Of It Operations jobs?

The most popular types of Of It Operations jobs are:

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States with the most job openings for Vice President Of It Operations jobs include:

What job categories do people searching Vice President Of It Operations jobs look for?

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Vice President Of It Operations jobs near you
Infographic showing various Vice President Of It Operations job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 84% Full Time, 11% Part Time, 1% Temporary, 2% Contract, and 1% Nights. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $155,780 per year, or $74.9 per hour.

Vice President of Information Technology

MBX Biosciences

Burlington, MA • On-site

$170K - $213K/yr

Full-time

Posted 22 days ago

Job description

Position Summary
MBX Biosciences is seeking an experienced and visionary Vice President of Information Technology (IT) to lead the company's technology strategy, infrastructure, applications, cybersecurity, data governance, and digital innovation initiatives. Reporting to our Chief Financial Officer, the VP of IT will be responsible for developing and executing an enterprise-wide IT strategy that supports MBX's research, clinical, commercial, and corporate business objectives. As MBX advances toward and through commercialization, this leader will bring experience supporting commercial organizations, including sales, marketing, market access, and patient services functions.
This role will also champion the evaluation and adoption of emerging technologies, including artificial intelligence (AI), advanced analytics, and digital transformation solutions that improve productivity, decision-making, and business outcomes. The VP of IT will build, develop, and lead a high-performing IT organization while overseeing technology operations across MBX's hubs and remote workforce.
Key Responsibilities
Strategic Leadership
  • Develop and execute MBX's enterprise IT vision, roadmap, and long-term technology strategy aligned with corporate objectives.
  • Build, lead, mentor, and develop a high-performing IT team capable of supporting MBX's evolving business needs.
  • Partner with executive leadership to identify technology opportunities that enhance business performance and support organizational growth.
  • Lead the design and evolution of scalable IT architecture, systems, infrastructure, and platforms that support research, development, clinical operations, commercial activities, and corporate functions.
  • Establish technology governance, policies, standards, and operating models across the organization.

Commercial & Business Enablement
  • Support commercial readiness and ongoing commercial operations through the implementation and optimization of technology solutions for sales, marketing, market access, patient support, and customer engagement.
  • Collaborate with commercial leadership to ensure systems effectively support business objectives, customer relationships, data analytics, and operational efficiency.
  • Partner with functional leaders to evaluate, prioritize, and implement technology investments that drive business value.

Artificial Intelligence & Digital Innovation
  • Develop and lead MBX's artificial intelligence strategy, identifying opportunities to leverage AI, automation, machine learning, and advanced analytics across the enterprise.
  • Evaluate emerging technologies and recommend solutions that improve operational effectiveness, decision-making, and employee productivity.
  • Establish responsible AI governance practices, ensuring compliance, security, and ethical use of AI-enabled solutions.
  • Foster a culture of innovation and continuous improvement throughout the organization.

IT Operations & Infrastructure
  • Oversee enterprise applications, cloud services, infrastructure, network operations, service delivery, end-user support, and cybersecurity programs.
  • Ensure high levels of system availability, reliability, security, and performance.
  • Lead disaster recovery, business continuity, and risk management initiatives.
  • Manage technology vendors, service providers, and strategic partnerships.

Cybersecurity, Compliance & Data Governance
  • Establish and maintain a comprehensive cybersecurity strategy and risk management framework.
  • Ensure compliance with applicable regulatory requirements, industry standards, and data privacy regulations.
  • Oversee data governance, data integrity, and information management practices.
  • Develop and monitor security policies, controls, and employee awareness programs.

Workforce & Site Support
  • Oversee technology operations, infrastructure, and user support across MBX's two hub locations and remote workforce.
  • Ensure seamless collaboration, connectivity, security, and user experience across all work environments.
  • Support workplace technology initiatives that enable flexible and efficient ways of working.

Education & Qualifications
  • Bachelor's degree in Information Technology, Computer Science, Engineering, Business, or a related field; advanced degree preferred.
  • 15+ years of progressive IT leadership experience, including senior-level leadership roles.
  • Experience developing and executing enterprise IT strategies within biotechnology, pharmaceutical, life sciences, healthcare, or highly regulated industries.
  • Demonstrated experience supporting organizations through commercial growth and commercialization activities.
  • Proven success leading enterprise technology architecture, infrastructure, applications, cybersecurity, and digital transformation initiatives.
  • Experience building, leading, and scaling high-performing IT teams.
  • Strong knowledge of cloud technologies, enterprise applications, data management, cybersecurity frameworks, and modern IT operating models.
  • Experience overseeing multi-site operations and supporting distributed and remote workforces.
  • Demonstrated ability to manage complex vendor relationships and technology budgets.
  • Experience supporting pre-commercial, commercial-stage, or rapidly growing biotechnology organizations.
  • Strong executive presence with the ability to influence and collaborate across all levels of the organization.

Travel
You will be expected to travel periodically based on the needs of the business to the extent requested by the Company, including attendance at Together Weeks, Together Days, and functional meetings as requested by the Company.
Company Overview:
MBX Biosciences is a biopharmaceutical company focused on the discovery, development and commercialization of novel precision peptide therapies based on its proprietary PEP™ platform, for the treatment of endocrine and metabolic disorders. The Company is advancing a pipeline of novel candidates for endocrine and metabolic disorders with clinically validated targets, established endpoints for regulatory approval, significant unmet medical needs and large potential market opportunities. The Company's pipeline includes canvuparatide (MBX 2109) for the treatment of chronic hypoparathyroidism preparing for Phase 3 development; and an obesity portfolio that includes MBX 4291 in Phase 1 development and MBX 5765 in preclinical development, as well as additional discovery candidates. The Company is based in Carmel, Indiana and Burlington, Massachusetts. To learn more, please visit the Company website at www.mbxbio.com and follow it on LinkedIn.
EEO Statement:
MBX Biosciences is an Equal Opportunity Employer and is committed to treating all applicants fairly without discrimination. We welcome applications from all individuals, regardless of race, national origin, gender, age, physical characteristics, social origin, disability, union membership, religion, family status, pregnancy, sexual orientation, gender identity, gender expression or any unlawful criterion under applicable law.

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