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Manager Variant Scientist Jobs (NOW HIRING)

With experts in biomedical science, software engineering, and program management, we focus on ... Provide bioinformatics support to include somatic and germline variant calling and analysis, single ...

With experts in biomedical science, software engineering, and program management, we focus on ... Provide bioinformatics support to include somatic and germline variant calling and analysis, single ...

With experts in biomedical science, software engineering, and program management, we focus on ... Provide bioinformatics support to include somatic and germline variant calling and analysis, single ...

Experience with standard bioinformatics tools (e.g., alignment tools, variant callers, single-cell ... Proven ability to thrive in a fast-paced environment, manage multiple projects simultaneously, and ...

Operate established Sanger sequencing pipelines, including assembly, trimming, QC, variant calling ... Manage the informatics queue by receiving analysis requests, scoping deliverables, setting timeline ...

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Manager Variant Scientist information

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$36.5K

$79.4K

$137.5K

How much do manager variant scientist jobs pay per year?

As of Aug 14, 2026, the average yearly pay for manager variant scientist in the United States is $79,408.00, according to ZipRecruiter salary data. Most workers in this role earn between $57,500.00 and $93,000.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a manager variant scientist?

To excel as a Manager Variant Scientist, you need a strong background in genetics, molecular biology, and bioinformatics, often supported by a PhD and relevant laboratory experience. Familiarity with genomic analysis tools, next-generation sequencing (NGS) platforms, and variant interpretation databases is typically required. Leadership, effective communication, and project management skills help in guiding teams and collaborating with cross-functional stakeholders. These competencies are vital for ensuring accurate variant analysis, driving scientific advancements, and successfully managing complex research projects.

What is the difference between Manager Variant Scientist vs Variant Scientist?

AspectManager Variant ScientistVariant Scientist
CredentialsBachelor's or Master's in Life Sciences, Biotech, or related fields; often with leadership experienceBachelor's or Master's in Life Sciences, Biotech, or related fields
Work EnvironmentLeads teams in R&D or manufacturing settings, overseeing variant developmentPerforms laboratory research, data analysis, and variant testing
Employer & Industry UsagePharmaceutical, biotech, or biotech manufacturing companiesResearch institutions, biotech firms, pharmaceutical companies

The main difference is that a Manager Variant Scientist oversees teams and projects, focusing on leadership and strategic planning, while a Variant Scientist primarily conducts laboratory research and data analysis. Both roles require similar technical credentials, but the managerial position adds responsibilities related to team management and project coordination.

What is a manager variant scientist?

A Manager Variant Scientist is a professional who leads a team responsible for analyzing genetic variants, often within clinical or research laboratories. They oversee the interpretation of genomic data to identify mutations or variations relevant to patient care, disease research, or drug development. In addition to hands-on scientific analysis, they manage workflows, ensure data quality, and coordinate collaboration between scientists, clinicians, and other stakeholders. This role typically requires expertise in genetics, molecular biology, bioinformatics, and strong leadership skills.

What are some common challenges faced by a manager variant scientist when leading a genomics team?

A Manager Variant Scientist often encounters challenges such as balancing hands-on scientific analysis with leadership responsibilities, ensuring data accuracy and compliance with regulatory standards, and managing cross-functional communication between laboratory staff, bioinformaticians, and clinicians. Additionally, keeping up with rapid advancements in sequencing technologies and variant interpretation guidelines can be demanding. Effective managers foster a collaborative environment, provide mentorship, and prioritize continuous learning to overcome these challenges and maintain high-quality results.
More about Manager Variant Scientist jobs

What cities are hiring for Manager Variant Scientist jobs?

Cities with the most Manager Variant Scientist job openings:

What are the most commonly searched types of Variant Scientist jobs?

The most popular types of Variant Scientist jobs are:

What states have the most Manager Variant Scientist jobs?

States with the most job openings for Manager Variant Scientist jobs include:

Infographic showing various Manager Variant Scientist job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 86% Full Time, 12% Part Time, and 1% Contract. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $79,408 per year, or $38.2 per hour.

Curation Scientist Biomarker & Drug Intelligence - Precision Oncology or Hematology

Caris Life Sciences

Tempe, AZ • On-site

$34.25 - $43/hr

Full-time

Re-posted 4 days ago


Job description

At Caris, we understand that cancer is an ugly word-a word no one wants to hear, but one that connects us all. That's why we're not just transforming cancer care-we're changing lives.
We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day: "What would I do if this patient were my mom?" That question drives everything we do.
But our mission doesn't stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare-driven by innovation, compassion, and purpose.
Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins.
Position Summary
The Curation Scientist, Biomarker & Drug Intelligence - Precision Oncology or Hematology, is a key member of the Biomarker & Drug Intelligence team and supports the development, maintenance, and continuous improvement of the knowledgebase that powers Caris Molecular Intelligence and other Caris products. This role identifies, evaluates, synthesizes, and documents scientific and clinical evidence related to oncology and hematology biomarkers, molecular alterations, tumor biology, and therapeutic relevance in precision oncology.
Job Responsibilities
  • Monitor emerging scientific, medical, and clinical literature, clinical guidelines, and public databases relevant to oncology and hematology biomarkers and therapies.
  • Evaluate and curate evidence related to cancer biology, molecular oncology, targeted therapy, immuno-oncology, hereditary cancer risk, hematologic malignancies, and related disease areas.
  • Develop clear, structured documentation to support knowledgebase updates, biomarker interpretations, report content, and therapeutic associations.
  • Translate complex scientific findings into actionable content for clinical, product, and operational use.
  • Collaborate with cross-functional teams to review proposed changes and ensure evidence interpretation aligns with product requirements.
  • Present scientific findings and evidence-based recommendations to internal stakeholders.
  • Support quality assurance and implementation activities to ensure approved updates are accurately reflected across products and workflows.
  • Contribute to process improvement initiatives, training materials, scientific summaries, presentations, and other special projects as needed.

Required Qualifications
  • Ph.D. in oncology, cancer biology, molecular biology, genetics, genomics, hematology, pharmacology, or a related scientific discipline, or a Master's degree with relevant experience.
  • Minimum of 3-5 years of experience in literature curation, scientific evidence assessment, or scientific review within molecular diagnostics, oncology, hematology, biotechnology, pharmaceutical, or healthcare environments.
  • Demonstrated ability to critically evaluate scientific and clinical literature and assess evidence strength and relevance.
  • Strong written and verbal communication skills with the ability to clearly summarize complex scientific information.
  • Excellent attention to detail, organization, and documentation skills.
  • Ability to manage multiple priorities and work effectively in a fast-paced, cross-functional environment.
  • Proficiency with scientific and clinical resources including PubMed, NCCN guidelines, ClinVar, COSMIC, OncoKB, CIViC, and ClinicalTrials.gov.
  • Proficient in Microsoft Office Suite, including Word, Excel, Outlook, and general working knowledge of internet-based business tools.

Preferred Qualifications
  • Experience in precision oncology, molecular diagnostics, oncology biomarker interpretation, or hematologic malignancies.
  • Familiarity with somatic and germline variant interpretation, clinical guidelines, and evidence grading frameworks.
  • Experience supporting knowledgebase curation, clinical content development, or rules-based implementation workflows.

Physical Demands
  • Primarily sedentary work involving prolonged periods of sitting. Occasional standing, walking, and use of standard office equipment such as computers and telephones. Ability to communicate effectively and review detailed scientific and clinical documentation.

Training
  • All job-specific, safety, and compliance training are assigned based on the job functions associated with this position.

Other
  • This position may require occasional evenings, weekends, or additional hours to meet business needs or project deadlines.

Conditions of Employment: Individual must successfully complete pre-employment process, which includes criminal background check, drug screening, credit check ( applicable for certain positions) and reference verification.
This job description reflects management's assignment of essential functions. Nothing in this job description restricts management's right to assign or reassign duties and responsibilities to this job at any time.
Caris Life Sciences is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, gender, gender identity, sexual orientation, age, status as a protected veteran, among other things, or status as a qualified individual with disability.