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Manager Variant Scientist Jobs in California (NOW HIRING)

Bioinformatics Engineer - Variant

San Francisco, CA ยท On-site +1

$120K - $180K/yr

... scientists across 150+ R&D labs to handle data from instrument-to-insights. We're seeking a ... Candidates with all of the above qualifications + proven management skills will be eligible for ...

Scientific Sales, Oncology

San Diego, CA ยท On-site

$80K - $120K/yr

... and large structural variant detection, de novo chromosome assembly, haplotype phasing ... We are seeking a vibrant, purposeful, and competent Sales Manager for the Western Americas Sales ...

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Manager Variant Scientist information

What are the key skills and qualifications needed to thrive as a Manager Variant Scientist, and why are they important?

To excel as a Manager Variant Scientist, you need a strong background in genetics, molecular biology, and bioinformatics, often supported by a PhD and relevant laboratory experience. Familiarity with genomic analysis tools, next-generation sequencing (NGS) platforms, and variant interpretation databases is typically required. Leadership, effective communication, and project management skills help in guiding teams and collaborating with cross-functional stakeholders. These competencies are vital for ensuring accurate variant analysis, driving scientific advancements, and successfully managing complex research projects.

What is the difference between Manager Variant Scientist vs Variant Scientist?

AspectManager Variant ScientistVariant Scientist
CredentialsBachelor's or Master's in Life Sciences, Biotech, or related fields; often with leadership experienceBachelor's or Master's in Life Sciences, Biotech, or related fields
Work EnvironmentLeads teams in R&D or manufacturing settings, overseeing variant developmentPerforms laboratory research, data analysis, and variant testing
Employer & Industry UsagePharmaceutical, biotech, or biotech manufacturing companiesResearch institutions, biotech firms, pharmaceutical companies

The main difference is that a Manager Variant Scientist oversees teams and projects, focusing on leadership and strategic planning, while a Variant Scientist primarily conducts laboratory research and data analysis. Both roles require similar technical credentials, but the managerial position adds responsibilities related to team management and project coordination.

What is a Manager Variant Scientist?

A Manager Variant Scientist is a professional who leads a team responsible for analyzing genetic variants, often within clinical or research laboratories. They oversee the interpretation of genomic data to identify mutations or variations relevant to patient care, disease research, or drug development. In addition to hands-on scientific analysis, they manage workflows, ensure data quality, and coordinate collaboration between scientists, clinicians, and other stakeholders. This role typically requires expertise in genetics, molecular biology, bioinformatics, and strong leadership skills.

What are some common challenges faced by a Manager Variant Scientist when leading a genomics team?

A Manager Variant Scientist often encounters challenges such as balancing hands-on scientific analysis with leadership responsibilities, ensuring data accuracy and compliance with regulatory standards, and managing cross-functional communication between laboratory staff, bioinformaticians, and clinicians. Additionally, keeping up with rapid advancements in sequencing technologies and variant interpretation guidelines can be demanding. Effective managers foster a collaborative environment, provide mentorship, and prioritize continuous learning to overcome these challenges and maintain high-quality results.
What are the most commonly searched types of Variant Scientist jobs in California? The most popular types of Variant Scientist jobs in California are:
What cities in California are hiring for Manager Variant Scientist jobs? Cities in California with the most Manager Variant Scientist job openings:
Infographic showing various Manager Variant Scientist job openings in California as of July 2026, with employment types broken down into 94% Full Time, 2% Part Time, and 4% Contract. Highlights an 88% In-person, 4% Hybrid, and 8% Remote job distribution.

Bioinformatics Engineer - Variant

LatchBio

San Francisco, CA โ€ข On-site, Remote

$120K - $180K/yr

Full-time

Re-posted 28 days ago


Job description

Bioinformatics Engineer - Variant
As molecular data generation and frontier model intelligence grows, new approaches to data analysis are needed across the biotech industry. Latch is building intelligent, high-performance agents for biological data analysis, empowering over 5,000 scientists across 150+ R&D labs to handle data from instrument-to-insights.
We're seeking a Bioinformatics Engineerto join our Variant team working at the frontier of what artificial intelligence can achieve in biology.
About the Role
You'll design, build, and evaluate LLM benchmarks for genomic analysis - spanning read alignment, assembly, variant calling, GWAS, causal inference, and multiomics integration. Your benchmarks and evaluations will set the bar for how well AI agents can serve as analysis partners for scientists working with human genetics data.
You'll own the full evaluation pipeline: choosing datasets, defining failure modes, writing grading scripts, and shipping evaluations that measure real capability. Your work directly impacts how LLMs reason through genomic problems.
Requirements
  • Master's or PhD in bioinformatics, genetics, biology, statistics, or related field
  • 3-5 years of hands-on research experience analyzing genomics datasets (especially human data), demonstrated through publications or industry work
  • Deep expertise in at least one of: population genetics, statistical genetics, clinical genomics
  • Fluency with genotyping workflows: variant calling, fine-mapping, Mendelian randomization

Nice-to-Have
  • Experience building open-source bioinformatics software
  • Familiarity with LLM-powered tools, prompting, or evaluation frameworks
  • Background in cross-trait analysis or multiomics integration

Culture @ Latch
How we work. Genuinely flexible schedules - we just ask that you communicate when you're coming in later than usual. We care most about hard work and output. We're respectfully opinionated, it will always be us against problems, not each other. Optimize for each other's time and bring solutions, not just problems. You'll join a bench suited to your expertise, but we value cross-domain learning and interoperability across teams.
The office & perks. Waterfront office near Oracle Park, 2x free daily meals, unlimited snacks, company outings most months, and team offsites. Plus a vibrant community: cycling, soccer, figure skating, boxing, run clubs, reading clubs, martial arts, music, game nights.
Compensation & Logistics
  • 1099 (or W8-BEN) contract, 40 hrs/week, no end date
  • Fully performance-based pay: $120K-$180K, uncapped upside. 2x quota = 2x pay.
  • 2-4 week paid ramp - full OTE from day one
  • Remote (globally), hybrid, or onsite in SF (onsite preferred)
  • Work authorization: OPT visa holders only (not STEM Extension)
  • Onsite perks: 2x free meals/day, waterfront office (China Basin), monthly parking (based on availability)
  • Candidates with all of the above qualifications + proven management skills will be eligible for more senior positions

Interview Process
Timeline: We move fast: 8-12 days from submission to offer.
  1. Intro Screen - Techcnial Recruiter
  2. Take-Home Project - HackerRank
  3. Technical Interview - Member of Technical Staff
  4. Culture Interview - C-Suite (If applicable)
  5. Offer

LatchBio logo

About LatchBio

Sourced by ZipRecruiter

Industry

Biotechnology research and development

Company size

11 - 50 Employees

Headquarters location

San Francisco, CA, US

Year founded

2021

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