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Trainee Variant Curation Scientist Jobs (NOW HIRING)

Exact Sciences

Sr Product Owner

San Diego, CA · On-site

Help us change lives At Exact Sciences, we're helping change how the world prevents, detects and ... Understand end-to-end sample to answer workflows, including bioinformatics output, variant curation ...

Exactsciences

Sr Product Owner

San Diego, CA · On-site

Help us change lives At Exact Sciences, we're helpingchange how the world prevents, detects and ... Understand end-to-endsampletoanswerworkflows, including bioinformatics output, variant curation ...

Nationwide Children's Hospital

... Scientists ... Assists with the day-to-day operations of variant assessment, curation, and documentation to ...

Nationwide Children's Hospital

... Scientists. Assists with the day-to-day operations of variant assessment, curation, and documentation to accurately identify and classify genomic alterations detected through genomic testing and ...

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How much do trainee variant curation scientist jobs pay per hour?

As of Jun 10, 2026, the average hourly pay for trainee variant curation scientist in the United States is $38.99, according to ZipRecruiter salary data. Most workers in this role earn between $33.89 and $42.55 per hour, depending on experience, location, and employer.

What does a Trainee Variant Curation Scientist do?

A Trainee Variant Curation Scientist assists in the interpretation of genetic variants, often as part of a clinical or research laboratory team. Their main responsibilities include analyzing DNA sequencing data, researching scientific literature, and classifying genetic variants according to established guidelines (such as ACMG/AMP). Under supervision, they learn to use bioinformatics tools and databases to assess the significance of genetic changes and help generate reports that inform patient care or research outcomes. This role is foundational for individuals seeking to develop expertise in genomic medicine and variant analysis.

What are some common challenges faced by Trainee Variant Curation Scientists, and how can they be addressed?

Trainee Variant Curation Scientists often encounter challenges such as interpreting complex genetic data, staying current with rapidly evolving guidelines, and distinguishing between benign and pathogenic variants. To address these, trainees benefit from strong mentorship, frequent collaboration with experienced scientists, and participation in regular case discussions. Utilizing established databases and adhering to standardized protocols also helps ensure accuracy and consistency in variant interpretation.

What is the difference between Trainee Variant Curation Scientist vs Variant Curation Scientist?

AspectTrainee Variant Curation ScientistVariant Curation Scientist
Required CredentialsTypically entry-level, often requiring a relevant degree in genetics, biology, or related fieldUsually requires more experience or advanced degrees, with some certifications preferred
Work EnvironmentTraining setting, supervised tasks, learning-focusedIndependent work, responsible for curation and interpretation of variants
Employer & Industry UsageCommon in biotech, research institutions, and diagnostic labs during training phasesFull-time role in similar settings, with increased responsibilities

The main difference is that a Trainee Variant Curation Scientist is in a learning or entry-level phase, focusing on developing skills under supervision, whereas a Variant Curation Scientist is a more experienced professional responsible for interpreting genetic variants independently.

What are the key skills and qualifications needed to thrive as a Trainee Variant Curation Scientist, and why are they important?

To thrive as a Trainee Variant Curation Scientist, you need a solid background in genetics, molecular biology, and bioinformatics, often supported by a relevant bachelor's or master's degree. Familiarity with genomic databases, variant annotation tools, and interpretation guidelines such as ACMG/AMP is typically required. Attention to detail, critical thinking, and strong written communication skills help you accurately assess and report genetic variants. These skills ensure precise variant classification, which is crucial for reliable genetic diagnoses and patient care.
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Trainee Variant Curation Scientist jobs near you
Infographic showing various Trainee Variant Curation Scientist job openings in the United States as of June 2026, with employment types broken down into 89% Full Time, and 11% Part Time. Highlights an 86% In-person, 3% Hybrid, and 11% Remote job distribution, with an average salary of $81,095 per year, or $39 per hour.
Clinical Genomics Variant Scientist

Clinical Genomics Variant Scientist

UCLA Health

Los Angeles, CA

$105K - $234K/yr

Full-time

Posted 12 days ago

UCLA Health rating

8.7

Company rating: 8.7 out of 10

Based on 134 frontline employees who took The Breakroom Quiz

6th of 870 rated healthcare providers

Job description

Description

The Molecular Diagnostics Laboratory is seeking an experienced Variant Scientist to join our clinical team. In this critical role, you will curate and interpret germline and somatic variants and prepare high-quality clinical reports derived from exome and targeted cancer sequencing assays. You will contribute to variant classification, test development efforts, and clinical research projects that advance precision medicine for patients across UCLA Health and beyond. Primary duties include:

• Review and assess patient clinical notes and sequencing data from high-complexity molecular assays, including Clinical Exome Sequencing, Solid Tumor Sequencing Panels, and Hematologic Malignancy Sequencing Panels.

• Perform variant curation and interpretation using established guidelines and evidence-based resources.

• Draft and refine clinical reports, ensuring accuracy, clarity, and clinical relevance.

• Develop and update SOPs for variant curation, interpretation, and reclassification workflows

• Participate in submitting curated variants to public databases (e.g. ClinVar) and contribute to quality improvement and test development initiatives.

• Collaborate with clinicians, genetic counselors, and laboratory staff to support accurate and timely reporting.

• Contribute to clinical research projects and assist in implementing new molecular diagnostic assays.

Salary Range: $105,700.00 - $234,500.00/year 

Qualifications
• At least two years’ experience in germline variant curation is required. Somatic variant curation experience is a plus.
• Strong working knowledge of laboratory genetics and genomics, including target capture, amplification, and massively parallel sequencing.
• Familiarity with widely used genomic tools such as IGV and UCSC/COSMIC genome browsers
• Ability to establish effective working relationships with clinicians, genetic counselors, and other team members.
• Programming or bioinformatics experience (e.g. R, SAS, Perl, Python, regex, database design) – preferred.
• PhD in human genetics, molecular genetics, cancer biology, or a related discipline – preferred. Master’s degree in molecular biology, genetics, or a closely related field may be considered with relevant experience.

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About UCLA Health

Sourced by ZipRecruiter

UCLA Health, operating within the healthcare industry, is significantly recognized for its commitment to improving the health and wellbeing of people through the integration of patient care, research, and education. Located in Los Angeles, California, UCLA Health was founded and associated with the University of California, Los Angeles (UCLA) in 1955, entrenching its roots in quality healthcare service provision. Through a broad range of medical services, UCLA Health significantly stands as a cornerstone for comprehensive outpatient, inpatient, and emergency care services, specialized treatments, and wellness checks. Notable for pioneering an integrated, comprehensive medical approach, UCLA Health is consistently ranked among the top health systems in the US and world.

Industry

Health care and social assistance

Company size

10,000+ Employees

Headquarters location

Los Angeles, CA, US

Year founded

1955

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