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Trainee Variant Curation Scientist Jobs in Michigan

We are committed to inspiring the next generation of scientists and educators. The Van Andel ... Learn more about VAI's dedication to investing in postdoctoral trainees and the recently announced ...

We are committed to inspiring the next generation of scientists and educators. The Van Andel ... Learn more about VAI's dedication to investing in postdoctoral trainees and the recently announced ...

Trainee Variant Curation Scientist information

What does a trainee variant curation scientist do?

A Trainee Variant Curation Scientist assists in the interpretation of genetic variants, often as part of a clinical or research laboratory team. Their main responsibilities include analyzing DNA sequencing data, researching scientific literature, and classifying genetic variants according to established guidelines (such as ACMG/AMP). Under supervision, they learn to use bioinformatics tools and databases to assess the significance of genetic changes and help generate reports that inform patient care or research outcomes. This role is foundational for individuals seeking to develop expertise in genomic medicine and variant analysis.

What are some common challenges faced by trainee variant curation scientists, and how can they be addressed?

Trainee Variant Curation Scientists often encounter challenges such as interpreting complex genetic data, staying current with rapidly evolving guidelines, and distinguishing between benign and pathogenic variants. To address these, trainees benefit from strong mentorship, frequent collaboration with experienced scientists, and participation in regular case discussions. Utilizing established databases and adhering to standardized protocols also helps ensure accuracy and consistency in variant interpretation.

What are the key skills and qualifications needed to thrive as a trainee variant curation scientist, and why are they important?

To thrive as a Trainee Variant Curation Scientist, you need a solid background in genetics, molecular biology, and bioinformatics, often supported by a relevant bachelor's or master's degree. Familiarity with genomic databases, variant annotation tools, and interpretation guidelines such as ACMG/AMP is typically required. Attention to detail, critical thinking, and strong written communication skills help you accurately assess and report genetic variants. These skills ensure precise variant classification, which is crucial for reliable genetic diagnoses and patient care.

What is the difference between Trainee Variant Curation Scientist vs Variant Curation Scientist?

AspectTrainee Variant Curation ScientistVariant Curation Scientist
Required CredentialsTypically entry-level, often requiring a relevant degree in genetics, biology, or related fieldUsually requires more experience or advanced degrees, with some certifications preferred
Work EnvironmentTraining setting, supervised tasks, learning-focusedIndependent work, responsible for curation and interpretation of variants
Employer & Industry UsageCommon in biotech, research institutions, and diagnostic labs during training phasesFull-time role in similar settings, with increased responsibilities

The main difference is that a Trainee Variant Curation Scientist is in a learning or entry-level phase, focusing on developing skills under supervision, whereas a Variant Curation Scientist is a more experienced professional responsible for interpreting genetic variants independently.

What are the most commonly searched types of Variant Curation Scientist jobs in Michigan?

The most popular types of Variant Curation Scientist jobs in Michigan are:

What cities in Michigan are hiring for Trainee Variant Curation Scientist jobs?

Cities in Michigan with the most Trainee Variant Curation Scientist job openings:

Infographic showing various Trainee Variant Curation Scientist job openings in Michigan as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution.

Full-time

Posted 4 days ago


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Job description

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Office

Job Description

As part of the Thermo Fisher Scientific team, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life every single day to enable our customers to make the world healthier, cleaner and safer. We provide our global teams with the resources needed to achieve individual career goals while helping to take science a step beyond by developing solutions for some of the world’s toughest challenges, like protecting the environment, making sure our food is safe or helping find cures for cancer.
Discover Impactful Work
The Variant Scientist III will review, analyze, and compile complex clinical data from primary literature and clinical trials specific to biomarkers in cancer. You’ll provide scientific and technical expertise to a cross-functional team of scientists and software developers to build and maintain an internal knowledgebase of genomic aberrations and therapies relevant to cancer.  This role is part of the Bioinformatics team within the Clinical Next Generation Sequencing Division. The mission of this business unit is to develop next-generation sequencing-based solutions to support oncology research and other important unmet medical needs.
 

Location

This is a fully onsite role based in Ann Arbor, MI and relocation assistance is not provided. 

A Day in the Life

  • Read, interpret, and curate evidence from approved therapies, clinical guidelines, clinical trials, and scientific literature using customized software tools.
  • Actively participate in the interpretation, analysis, and summarization of various clinical sources for somatic and germline variant annotations and classification.
  • Review primary literature and author summaries that describe the relationships between gene variants and disease prognosis, diagnosis, and therapy selection.
  • Actively provide translational and clinical oncology expertise to the curation team in solid and/or hematological cancers.
  • Follow and maintain sustainable processes that ensure data accuracy and quality.
  • Work in a fast pace, cross-functional team of bioinformatics scientists, variant scientists, and software engineers to define and refine clinical reports.

Keys to Success

Education

  • PhD in cancer biology, cancer genomics, or molecular biology with expertise in solid or heme cancers. Post-doctoral experience preferred but not required.

Experience

  • Demonstrated understanding of cancer genomics, tumor biology, oncogenic signaling pathways.
  • Experience in reviewing and summarizing scientific literature for somatic and germline variants.
  • Experience with cancer mutation databases and disease ontologies.
  • Industry or clinical laboratory experience working in genomic variant curation and clinical interpretation is preferred.
  • Experience with IVD/regulated product development or genetic counseling is a plus.

Knowledge, Skills, Abilities

  • Excellent written and oral communication skills.
  • Excellent organizational skills with ability to multi-task
  • Ability to work independently and collaboratively.
  • Positive attitude with strong interpersonal skills.

Other

  • Must be able to pass a comprehensive background check and drug screen.

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