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On Call Variant Curation Scientist Jobs (NOW HIRING)

Exactsciences

Sr Product Owner

San Diego, CA · On-site

Help us change lives At Exact Sciences, we're helpingchange how the world prevents, detects and ... Understand end-to-endsampletoanswerworkflows, including bioinformatics output, variant curation ...

Nationwide Children's Hospital

... Scientists ... Assists with the day-to-day operations of variant assessment, curation, and documentation to ...

Nationwide Children's Hospital

... Scientists. Assists with the day-to-day operations of variant assessment, curation, and documentation to accurately identify and classify genomic alterations detected through genomic testing and ...

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On Call Variant Curation Scientist information

What is an On Call Variant Curation Scientist?

An On Call Variant Curation Scientist is a genetics professional who evaluates and interprets genetic variants, often on an as-needed or flexible basis, to determine their clinical significance. They review scientific literature, databases, and laboratory data to classify genetic mutations, particularly in the context of patient care or research projects. Their expertise helps inform diagnostic decisions and supports genetic counseling. The 'on call' aspect means they are available to respond to urgent or time-sensitive variant curation requests outside of standard working hours.

What are the key skills and qualifications needed to thrive as an On Call Variant Curation Scientist, and why are they important?

To thrive as an On Call Variant Curation Scientist, you need a solid background in genetics, molecular biology, and clinical genomics, typically with an advanced degree in a life science field. Familiarity with bioinformatics tools, variant interpretation databases (such as ClinVar), and ACMG/AMP guidelines is essential, and certification from organizations like the American Board of Medical Genetics and Genomics (ABMGG) is often preferred. Excellent analytical thinking, attention to detail, and effective communication skills are crucial for interpreting data and collaborating with clinical teams. These competencies ensure accurate and timely variant classification, directly impacting patient care and genetic diagnosis.

What are the primary challenges faced by an On Call Variant Curation Scientist, and how can these be managed effectively?

On Call Variant Curation Scientists often encounter the challenge of rapidly interpreting complex genetic data while being available outside of standard working hours. This requires staying up-to-date with evolving scientific literature, managing urgent requests, and collaborating with clinical teams to ensure accurate and timely reporting. Effective time management, continuous learning, and strong communication skills are crucial for managing these demands. Leveraging robust databases and established protocols can also help streamline the variant curation process during on-call shifts.
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On Call Variant Curation Scientist jobs near you
Infographic showing various On Call Variant Curation Scientist job openings in the United States as of June 2026, with employment types broken down into 4% Locum Tenens, 2% Internship, 1% Full Time, 92% Contract, and 1% Summer. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution.