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What types of projects and responsibilities can an Intern Variant Curation Scientist expect during their internship?

As an Intern Variant Curation Scientist, you can expect to work closely with experienced scientists and bioinformaticians to evaluate genetic variants using databases, published literature, and established guidelines. Your daily tasks may include reviewing genetic data, annotating variants, and contributing to clinical reports or research projects. Interns often participate in team meetings, collaborate on data interpretation, and may even help improve curation processes or pipelines. This role provides hands-on exposure to genetic diagnostics and offers valuable insights into the workflow of clinical genomics teams.

What are the key skills and qualifications needed to thrive as an Intern Variant Curation Scientist, and why are they important?

To thrive as an Intern Variant Curation Scientist, you need a solid background in genetics, molecular biology, and bioinformatics, often supported by coursework or training in these areas. Familiarity with genomic databases, variant interpretation tools (such as ClinVar and ACMG guidelines), and data analysis software is typically required. Strong analytical thinking, attention to detail, and effective communication skills help in interpreting complex data and collaborating within research teams. These competencies are crucial for ensuring accurate genetic variant classification and supporting impactful clinical or research outcomes.

What does an Intern Variant Curation Scientist do?

An Intern Variant Curation Scientist assists with the analysis and interpretation of genetic variants, often working with large genomic datasets. Their main role is to review and classify genetic variants according to established guidelines to help determine their potential impact on health. This involves literature research, data annotation, and collaboration with senior scientists. The position provides hands-on experience in genetic data analysis and exposure to clinical genomics workflows.
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Infographic showing various Intern Variant Curation Scientist job openings in the United States as of July 2026, with employment types broken down into 69% Full Time, and 31% Part Time. Highlights an 92% In-person, and 8% Remote job distribution.
Clinical Genomic Scientist- Variant Curation

Clinical Genomic Scientist- Variant Curation

Baylor Genetics

Remote

Full-time

Posted 13 days ago

Job description

Summary:
The "Clinical Genomics Scientist" analyzes clinical genetics data, curates variants and genes, and summarizes findings for clinical reports. Our scientists assist laboratory directors and R&D with validation of cutting-edge technologies and software platforms.
Duties and Responsibilities:
  • Curation (50%): curation of variants, genes, and gene-disease correlation following ACMG guidelines
  • Analysis (30%): analyzing clinical genomics data, selecting variants for curation/confirmation, variant nomenclature following HGVS guidelines
  • Other (20%): may involve clinical report drafting, test validation, process refinement, presenting findings, monitoring test turnaround time

Qualifications/Experience
  • Degree: PhD or MD in clinical medicine, genetics, molecular biology, or equivalent. Or strong candidates with a Master's degree and relevant experience. Desired: MB(ASCP) certification.
  • 2-4 years of experience in clinical genomics or related fields (including postdoctoral appointments)
  • Thorough understanding of the American College of Medical Genetics (ACMG) variant curation guidelines.
  • Knowledge of genomic variation and its correlation with human disease.
  • Expertise in concepts of clinical medicine, genetics, genomics, or molecular biology.
  • Experience in data quality assessment and communicating genetic details effectively.
  • Excellence in reading/writing medical language.
  • Proficiency in Microsoft Office (Excel, Word, PowerPoint, Outlook).
  • Desired: experience in bioinformatics analysis, variant effect prediction algorithms, and scripting languages

Competencies:
Quality Assurance, Analytical, Problem Solving, Technical Skills, Interpersonal Skills, Oral and Written Communication, Teamwork, Organizational Support, Safety and Security, Dependability, Innovation, Adaptability.
Physical Demands and Work Environment:
  • At your Home Office:
    • Frequently required to sit, using screen, keyboard, and mouse.
    • Punctuality attending virtual meetings
    • Occasional weekend rotation may be needed (for example, once a month)

EEO Statement:
Baylor Genetics is proud to be an equal opportunity employer dedicated to building an inclusive and diverse workforce. We do not discriminate based on race, religion, color, national origin, sex, sexual orientation, age, gender identity, veteran status, disability, genetic information, pregnancy, childbirth, or related medical conditions, or any other status protected under applicable federal, state, or local law.
Equal Opportunity Employer
This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights notice from the Department of Labor.

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