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Intern Variant Curation Scientist Jobs (NOW HIRING)

Exactsciences

Sr Product Owner

San Diego, CA · On-site

Help us change lives At Exact Sciences, we're helpingchange how the world prevents, detects and ... Understand end-to-endsampletoanswerworkflows, including bioinformatics output, variant curation ...

Nationwide Children's Hospital

... Scientists ... Assists with the day-to-day operations of variant assessment, curation, and documentation to ...

Nationwide Children's Hospital

... Scientists. Assists with the day-to-day operations of variant assessment, curation, and documentation to accurately identify and classify genomic alterations detected through genomic testing and ...

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Intern Variant Curation Scientist information

What types of projects and responsibilities can an Intern Variant Curation Scientist expect during their internship?

As an Intern Variant Curation Scientist, you can expect to work closely with experienced scientists and bioinformaticians to evaluate genetic variants using databases, published literature, and established guidelines. Your daily tasks may include reviewing genetic data, annotating variants, and contributing to clinical reports or research projects. Interns often participate in team meetings, collaborate on data interpretation, and may even help improve curation processes or pipelines. This role provides hands-on exposure to genetic diagnostics and offers valuable insights into the workflow of clinical genomics teams.

What are the key skills and qualifications needed to thrive as an Intern Variant Curation Scientist, and why are they important?

To thrive as an Intern Variant Curation Scientist, you need a solid background in genetics, molecular biology, and bioinformatics, often supported by coursework or training in these areas. Familiarity with genomic databases, variant interpretation tools (such as ClinVar and ACMG guidelines), and data analysis software is typically required. Strong analytical thinking, attention to detail, and effective communication skills help in interpreting complex data and collaborating within research teams. These competencies are crucial for ensuring accurate genetic variant classification and supporting impactful clinical or research outcomes.

What does an Intern Variant Curation Scientist do?

An Intern Variant Curation Scientist assists with the analysis and interpretation of genetic variants, often working with large genomic datasets. Their main role is to review and classify genetic variants according to established guidelines to help determine their potential impact on health. This involves literature research, data annotation, and collaboration with senior scientists. The position provides hands-on experience in genetic data analysis and exposure to clinical genomics workflows.
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Infographic showing various Intern Variant Curation Scientist job openings in the United States as of June 2026, with employment types broken down into 18% Internship, 36% Full Time, and 46% Part Time. Highlights an 64% In-person, and 36% Remote job distribution.
Clinical Genomics Variant Scientist

Clinical Genomics Variant Scientist

UCLA Health

Los Angeles, CA

$105K - $234K/yr

Full-time

Posted 15 days ago

UCLA Health rating

8.7

Company rating: 8.7 out of 10

Based on 134 frontline employees who took The Breakroom Quiz

6th of 872 rated healthcare providers

Job description

Description

The Molecular Diagnostics Laboratory is seeking an experienced Variant Scientist to join our clinical team. In this critical role, you will curate and interpret germline and somatic variants and prepare high-quality clinical reports derived from exome and targeted cancer sequencing assays. You will contribute to variant classification, test development efforts, and clinical research projects that advance precision medicine for patients across UCLA Health and beyond. Primary duties include:

• Review and assess patient clinical notes and sequencing data from high-complexity molecular assays, including Clinical Exome Sequencing, Solid Tumor Sequencing Panels, and Hematologic Malignancy Sequencing Panels.

• Perform variant curation and interpretation using established guidelines and evidence-based resources.

• Draft and refine clinical reports, ensuring accuracy, clarity, and clinical relevance.

• Develop and update SOPs for variant curation, interpretation, and reclassification workflows

• Participate in submitting curated variants to public databases (e.g. ClinVar) and contribute to quality improvement and test development initiatives.

• Collaborate with clinicians, genetic counselors, and laboratory staff to support accurate and timely reporting.

• Contribute to clinical research projects and assist in implementing new molecular diagnostic assays.

Salary Range: $105,700.00 - $234,500.00/year 

Qualifications
• At least two years’ experience in germline variant curation is required. Somatic variant curation experience is a plus.
• Strong working knowledge of laboratory genetics and genomics, including target capture, amplification, and massively parallel sequencing.
• Familiarity with widely used genomic tools such as IGV and UCSC/COSMIC genome browsers
• Ability to establish effective working relationships with clinicians, genetic counselors, and other team members.
• Programming or bioinformatics experience (e.g. R, SAS, Perl, Python, regex, database design) – preferred.
• PhD in human genetics, molecular genetics, cancer biology, or a related discipline – preferred. Master’s degree in molecular biology, genetics, or a closely related field may be considered with relevant experience.

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About UCLA Health

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UCLA Health, operating within the healthcare industry, is significantly recognized for its commitment to improving the health and wellbeing of people through the integration of patient care, research, and education. Located in Los Angeles, California, UCLA Health was founded and associated with the University of California, Los Angeles (UCLA) in 1955, entrenching its roots in quality healthcare service provision. Through a broad range of medical services, UCLA Health significantly stands as a cornerstone for comprehensive outpatient, inpatient, and emergency care services, specialized treatments, and wellness checks. Notable for pioneering an integrated, comprehensive medical approach, UCLA Health is consistently ranked among the top health systems in the US and world.

Industry

Health care and social assistance

Company size

10,000+ Employees

Headquarters location

Los Angeles, CA, US

Year founded

1955

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