ZipRecruiter

Log In

1

Variant Curation Jobs (NOW HIRING)

Nationwide Children's Hospital

Assists with the day-to-day operations of variant assessment, curation, and documentation to accurately identify and classify genomic alterations detected through genomic testing and translational ...

Nationwide Children's Hospital

Assists with the day-to-day operations of variant assessment, curation, and documentation to accurately identify and classify genomic alterations detected through genomic testing and translational ...

next page

Showing results 1-20

All JobsVariant Curation Jobs

Variant Curation information

What are the key skills and qualifications needed to thrive in the Variant Curation position, and why are they important?

To thrive in Variant Curation, you need a solid background in genetics, molecular biology, and bioinformatics, often supported by a degree in a life science field. Familiarity with genomic databases, variant interpretation software (such as ClinVar or VarSome), and standards like ACMG/AMP guidelines is critical. Attention to detail, analytical thinking, and strong communication skills help you articulate findings and work with interdisciplinary teams. These competencies are essential for accurately interpreting genetic variants and contributing to clinical decision-making or research.

How do you get a job as a curator?

To become a variant curator, candidates typically need a background in genetics, bioinformatics, or related life sciences, along with experience using genomic databases and annotation tools. Relevant skills include data analysis, attention to detail, and familiarity with genetic variant interpretation standards. A bachelor's degree or higher in a relevant field is often required, and some positions may prefer or require certification or specialized training.

What are the typical responsibilities of a Variant Curation professional on a daily basis?

Variant Curation professionals are primarily responsible for reviewing and interpreting genetic variant data by analyzing scientific literature, databases, and applying industry standards to assess clinical significance. Daily tasks involve collaborating with genetic counselors, laboratory scientists, and clinicians to ensure accurate reporting and supporting patient management. The role also often includes documentation, updating curation databases, and participating in regular team meetings to discuss complex cases. Working in this position offers exposure to the latest developments in genomics and the opportunity to directly impact patient care and diagnostic outcomes.

How to become a variant scientist?

To become a variant scientist, typically a bachelor's degree in genetics, molecular biology, or a related field is required, often followed by a master's or Ph.D. for advanced roles. Skills in bioinformatics, data analysis, and familiarity with genetic databases and tools are essential, along with experience in laboratory or computational environments.

What does a variant curator do?

A variant curator reviews and annotates genetic variants identified in DNA sequencing data to determine their clinical significance. They analyze data using specialized tools, interpret the impact of variants on health, and ensure accurate classification for research or medical purposes. This role often requires knowledge of genetics, bioinformatics, and attention to detail.

Is there a demand for geneticists?

There is a strong demand for geneticists, especially in fields like medical genetics, research, and biotechnology. The increasing use of genetic testing and personalized medicine drives job growth, and roles often require advanced degrees and laboratory skills.

What is a Variant Curation job?

A Variant Curation job involves analyzing genetic variants to determine their clinical significance, primarily in the context of diseases like cancer or inherited disorders. Professionals in this role assess data from scientific literature, databases, and bioinformatics tools to classify variants based on established guidelines. Their work supports genetic testing labs, research institutions, and healthcare providers in making informed decisions about patient care. Strong analytical skills, understanding of genetics, and knowledge of bioinformatics tools are essential for success in this field.

More about Variant Curation jobs
What are the most commonly searched types of Variant Curation jobs? The most popular types of Variant Curation jobs are:
What states have the most Variant Curation jobs? States with the most job openings for Variant Curation jobs include:
What job categories do people searching Variant Curation jobs look for? The top searched job categories for Variant Curation jobs are:
Variant Curation jobs near you
Infographic showing various Variant Curation job openings in the United States as of June 2026, with employment types broken down into 1% Internship, 89% Full Time, 3% Part Time, and 7% Contract. Highlights an 85% Physical, 3% Hybrid, and 12% Remote job distribution.
Clinical Genomics Variant Scientist

Clinical Genomics Variant Scientist

UCLA Health

Los Angeles, CA

$105K - $234K/yr

Full-time

Posted 6 days ago

UCLA Health rating

8.7

Company rating: 8.7 out of 10

Based on 135 frontline employees who took The Breakroom Quiz

6th of 877 rated healthcare providers

Job description

Description

The Molecular Diagnostics Laboratory is seeking an experienced Variant Scientist to join our clinical team. In this critical role, you will curate and interpret germline and somatic variants and prepare high-quality clinical reports derived from exome and targeted cancer sequencing assays. You will contribute to variant classification, test development efforts, and clinical research projects that advance precision medicine for patients across UCLA Health and beyond. Primary duties include:

• Review and assess patient clinical notes and sequencing data from high-complexity molecular assays, including Clinical Exome Sequencing, Solid Tumor Sequencing Panels, and Hematologic Malignancy Sequencing Panels.

• Perform variant curation and interpretation using established guidelines and evidence-based resources.

• Draft and refine clinical reports, ensuring accuracy, clarity, and clinical relevance.

• Develop and update SOPs for variant curation, interpretation, and reclassification workflows

• Participate in submitting curated variants to public databases (e.g. ClinVar) and contribute to quality improvement and test development initiatives.

• Collaborate with clinicians, genetic counselors, and laboratory staff to support accurate and timely reporting.

• Contribute to clinical research projects and assist in implementing new molecular diagnostic assays.

Salary Range: $105,700.00 - $234,500.00/year 

Qualifications
• At least two years’ experience in germline variant curation is required. Somatic variant curation experience is a plus.
• Strong working knowledge of laboratory genetics and genomics, including target capture, amplification, and massively parallel sequencing.
• Familiarity with widely used genomic tools such as IGV and UCSC/COSMIC genome browsers
• Ability to establish effective working relationships with clinicians, genetic counselors, and other team members.
• Programming or bioinformatics experience (e.g. R, SAS, Perl, Python, regex, database design) – preferred.
• PhD in human genetics, molecular genetics, cancer biology, or a related discipline – preferred. Master’s degree in molecular biology, genetics, or a closely related field may be considered with relevant experience.

What UCLA Health employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom

UCLA Health logo

About UCLA Health

Sourced by ZipRecruiter

UCLA Health, operating within the healthcare industry, is significantly recognized for its commitment to improving the health and wellbeing of people through the integration of patient care, research, and education. Located in Los Angeles, California, UCLA Health was founded and associated with the University of California, Los Angeles (UCLA) in 1955, entrenching its roots in quality healthcare service provision. Through a broad range of medical services, UCLA Health significantly stands as a cornerstone for comprehensive outpatient, inpatient, and emergency care services, specialized treatments, and wellness checks. Notable for pioneering an integrated, comprehensive medical approach, UCLA Health is consistently ranked among the top health systems in the US and world.

Industry

Health care and social assistance

Company size

10,000+ Employees

Headquarters location

Los Angeles, CA, US

Year founded

1955

View All UCLA Health Jobs

Apply