Assists with the day-to-day operations of variant assessment, curation, and documentation to accurately identify and classify genomic alterations detected through genomic testing and translational ...
Assists with the day-to-day operations of variant assessment, curation, and documentation to accurately identify and classify genomic alterations detected through genomic testing and translational ...
Assists with the day-to-day operations of variant assessment, curation, and documentation to accurately identify and classify genomic alterations detected through genomic testing and translational ...
Assists with the day-to-day operations of variant assessment, curation, and documentation to accurately identify and classify genomic alterations detected through genomic testing and translational ...
Assists with the day-to-day operations of variant assessment, curation, and documentation to accurately identify and classify genomic alterations detected through genomic testing and translational ...
Assists with the day-to-day operations of variant assessment, curation, and documentation to accurately identify and classify genomic alterations detected through genomic testing and translational ...
Assists with the day-to-day operations of variant assessment, curation, and documentation to accurately identify and classify genomic alterations detected through genomic testing and translational ...
Assists with the day-to-day operations of variant assessment, curation, and documentation to accurately identify and classify genomic alterations detected through genomic testing and translational ...
Variant Curation information
What are the key skills and qualifications needed to thrive in the Variant Curation position, and why are they important?
To thrive in Variant Curation, you need a solid background in genetics, molecular biology, and bioinformatics, often supported by a degree in a life science field. Familiarity with genomic databases, variant interpretation software (such as ClinVar or VarSome), and standards like ACMG/AMP guidelines is critical. Attention to detail, analytical thinking, and strong communication skills help you articulate findings and work with interdisciplinary teams. These competencies are essential for accurately interpreting genetic variants and contributing to clinical decision-making or research.
How do you get a job as a curator?
To become a variant curator, candidates typically need a background in genetics, bioinformatics, or related life sciences, along with experience using genomic databases and annotation tools. Relevant skills include data analysis, attention to detail, and familiarity with genetic variant interpretation standards. A bachelor's degree or higher in a relevant field is often required, and some positions may prefer or require certification or specialized training.
What are the typical responsibilities of a Variant Curation professional on a daily basis?
Variant Curation professionals are primarily responsible for reviewing and interpreting genetic variant data by analyzing scientific literature, databases, and applying industry standards to assess clinical significance. Daily tasks involve collaborating with genetic counselors, laboratory scientists, and clinicians to ensure accurate reporting and supporting patient management. The role also often includes documentation, updating curation databases, and participating in regular team meetings to discuss complex cases. Working in this position offers exposure to the latest developments in genomics and the opportunity to directly impact patient care and diagnostic outcomes.
How to become a variant scientist?
To become a variant scientist, typically a bachelor's degree in genetics, molecular biology, or a related field is required, often followed by a master's or Ph.D. for advanced roles. Skills in bioinformatics, data analysis, and familiarity with genetic databases and tools are essential, along with experience in laboratory or computational environments.
What does a variant curator do?
A variant curator reviews and annotates genetic variants identified in DNA sequencing data to determine their clinical significance. They analyze data using specialized tools, interpret the impact of variants on health, and ensure accurate classification for research or medical purposes. This role often requires knowledge of genetics, bioinformatics, and attention to detail.
Is there a demand for geneticists?
There is a strong demand for geneticists, especially in fields like medical genetics, research, and biotechnology. The increasing use of genetic testing and personalized medicine drives job growth, and roles often require advanced degrees and laboratory skills.
What is a Variant Curation job?
A Variant Curation job involves analyzing genetic variants to determine their clinical significance, primarily in the context of diseases like cancer or inherited disorders. Professionals in this role assess data from scientific literature, databases, and bioinformatics tools to classify variants based on established guidelines. Their work supports genetic testing labs, research institutions, and healthcare providers in making informed decisions about patient care. Strong analytical skills, understanding of genetics, and knowledge of bioinformatics tools are essential for success in this field.
What are the most commonly searched types of Variant Curation jobs in Ohio? The most popular types of Variant Curation jobs in Ohio are:
What are popular job titles related to Variant Curation jobs in Ohio? For Variant Curation jobs in Ohio, the most frequently searched job titles are:
What job categories do people searching Variant Curation jobs in Ohio look for? The top searched job categories for Variant Curation jobs in Ohio are:
Full-time
Posted 15 days ago
Nationwide Children's Hospital rating
6.9
Based on 129 frontline employees who took The Breakroom Quiz
523rd of 1,004 rated hospitals
Job description
Overview:
Job Description Summary:
Job Description:
- Performs technical review of sequencing (Sanger and Next-Generation) and other molecular data.
- Provides accurate and timely variant assessment, including evaluation of published literature and clinical data to provide precise, thorough, and thoughtful clinical interpretation of results.
- Maintains laboratory variant knowledgebase. Assists with curation and harmonization of variant classification changes over time. Maintains knowledge of CAP laboratory requirements related to sequencing and variant analysis. Writes procedures and other documents in support of ongoing laboratory accreditation.
- Possesses knowledge of current theories and principals of human medical genetics, cancer genetics and hereditary cancer disorders.
- Thoroughly documents findings, per laboratory standard operating procedures. Assists with research, development, validation, and documentation of new genomic assays. Demonstrates knowledge of and upholds applicable laws and regulations. Maintains knowledge of techniques, procedures, and protocols. Reviews and acknowledges procedures as required.
- Assists in process development and improvement within the department including participating in quality assurance, continuing education programs, and department meetings.
Education Requirement:
- Master's Degree in molecular genetics, human genetics, or molecular pathology, required.
- PhD in biological sciences, preferred.
Licensure Requirement:
(not specified)
Certifications:
(not specified)
Skills:
- Strong analytical skills and ability to critically read and interpret data from scientific publications.
- Ability to do technical writing, as well as good communication and computer skills.
- Good organizational and interpersonal skills.
- Ability to initiate and work on several projects at a time with minimal supervision; motivation to follow through to completion while adhering to deadlines and maintaining accurate records.
Experience:
- Two years of significant and relevant experience including variant classification (including Genetic Counselors with relevant experience), required.
- Two years of experience in genetics, preferred.
- Extensive experience in data mining and organization.
Physical Requirements:
OCCASIONALLY: Bend/twist, Climb stairs/ladder, Flexing/extending of neck, Fume /Gases /Vapors, Hand use: grasping, gripping, turning, Lifting / Carrying: 11-20 lbs, Lifting / Carrying: 21-40 lbs, Loud Noises, Reaching above shoulder, Repetitive hand/arm use, Squat/kneel
FREQUENTLY: Standing, Walking
CONTINUOUSLY: Audible speech, Color vision, Computer skills, Decision Making, Depth perception, Hearing acuity, Interpreting Data, Lifting / Carrying: 0-10 lbs, Peripheral vision, Problem solving, Seeing - Far/near, Sitting
Additional Physical Requirements performed but not listed above:
The position requires excellent manual dexterity, good visual acuity and hearing, and excellent communication skills as well as a better-than-average ability to write.
"The above list of duties is intended to describe the general nature and level of work performed by individuals assigned to this classification. It is not to be construed as an exhaustive list of duties performed by the individuals so classified, nor is it intended to limit or modify the right of any supervisor to assign, direct, and control the work of employees under their supervision. EOE M/F/Disability/Vet"
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About Nationwide Children's Hospital
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Nationwide Children's Hospital, established in 1894, is a leading pediatric healthcare system based in Columbus, Ohio, United States. They serve as a primary pediatric network, providing wellness, preventive, diagnostic, treatment, and rehabilitative care for infants, children, adolescents, and adults with congenital disease. Being the third-largest pediatric hospital in the nation, Nationwide Children's Hospital prides itself on its relentless commitment to children and their families, driven by their core values of respect, integrity, determination, empathy, and solidarity. The institution's comprehensive mission is to enhance the health of children by providing high-quality, family-centered care, conducting groundbreaking research, advocating for pediatric health, and training top healthcare professionals.
Industry
Hospitals
Company size
10,000+ Employees
Headquarters location
Columbus, OH, US
Year founded
1892