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Bioprocess Engineer Jobs (NOW HIRING)

Krystal Biotech

Bioprocess Engineer

Coraopolis, PA · On-site

Krystal Biotech, Inc is seeking a highly motivated and dynamic Bioprocess Engineer to support our product manufacturing at our Pittsburgh GMP facility. This role is critical to our make a meaningful ...

EKF DIAGNOSTICS INC

Bioprocess Engineer

South Bend, IN · On-site

$75K - $95K/yr

Provides technical leadership in microbial fermentation and bioprocess operations. This role ... Bachelor of Science degree in an Engineering discipline (Chemical, Biochemical, Bioengineering, or ...

Bexorg, Inc.

Senior Bioprocess Engineer

New Haven, CT · On-site

$140K - $165K/yr

Senior Bioprocess Engineer Location: On-site, New Haven, CT Company: Bexorg (Bexorg.com) About Bexorg Bexorg is a TechBio company pioneering a completely new way to understand and treat ...

Krystal Biotech

Bioprocess Engineer

Moon Township, PA · On-site

Krystal Biotech, Inc is seeking a highly motivated and dynamic Bioprocess Engineer to support our product manufacturing at our Pittsburgh GMP facility. This role is critical to our make a meaningful ...

EKF Diagnostics Inc

Bioprocess Engineer

South Bend, IN · On-site

Provides technical leadership in microbial fermentation and bioprocess operations. This role ... Bachelor of Science degree in an Engineering discipline (Chemical, Biochemical, Bioengineering, or ...

Bexorg

Senior Bioprocess Engineer

New Haven, CT

Senior Bioprocess Engineer Location: On-site, New Haven, CT Company: Bexorg (Bexorg.com) About Bexorg Bexorg is a TechBio company pioneering a completely new way to understand and treat ...

EKF DIAGNOSTICS INC

Bioprocess Engineer

South Bend, IN · On-site

$75K - $95K/yr

Provides technical leadership in microbial fermentation and bioprocess operations. This role ... Bachelor of Science degree in an Engineering discipline (Chemical, Biochemical, Bioengineering, or ...

Bexorg

Senior Bioprocess Engineer

New Haven, CT · On-site

$140K - $165K/yr

Senior Bioprocess Engineer Location: On-site, New Haven, CT Company: Bexorg (Bexorg.com) About Bexorg Bexorg is a TechBio company pioneering a completely new way to understand and treat ...

millenniumsoft

Bioprocess Engineer

San Diego, CA · On-site

Job Title - Bioprocess Engineer Location - San Diego, CA Duration - 12+ Months Contract Total Hours/week - 40.00 The work hours is 40 hr/week with 75% travel to San Jose CA It is an onsite position.

Merz North America

BioProcess Engineer II

Racine, WI · On-site

A Brief Overview The BioProcess Engineer II leads the development, optimization, and support of manufacturing processes and equipment within a regulated medical device environment. This role manages ...

Merz North America

BioProcess Engineer II

Racine, WI

A Brief Overview The BioProcess Engineer II leads the development, optimization, and support of manufacturing processes and equipment within a regulated medical device environment. This role manages ...

millenniumsoft

Bioprocess/NPI Engineer

San Diego, CA · On-site

Bioprocess/NPI Engineer Location : San Diego, CA Duration : 12+ Months Total Hours/week : 40.00 1st shift Client: Medical Device Company Job Category: Healthcare Level Of Experience: Mid-Level ...

Lilly

Sr. Principal Engineer - Bioprocess

Richmond, VA · On-site

We are seeking a Sr. Principal Bioprocess Engineer to support our new Manufacturing Facility in Goochland County, Virginia. Process Engineering is core to delivering a right first-time facility start ...

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Bioprocess Engineer information

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How much do bioprocess engineer jobs pay per year?

As of Jun 9, 2026, the average yearly pay for bioprocess engineer in the United States is $82,999.00, according to ZipRecruiter salary data. Most workers in this role earn between $50,000.00 and $102,500.00 per year, depending on experience, location, and employer.

What Is Bioprocess Engineering?

A bioprocess engineer uses biological materials to create a variety of products. As a bioprocess engineer, you apply your biology and chemistry skills to create foods, products used in the agriculture industry, biofuels, pharmaceuticals, and water filtration systems, among other products. Qualifications for this career depend on the specific duties of a job, but you should obtain at least a bachelor’s degree in biology or chemistry. Most bioprocess engineers go on to pursue a graduate degree as well. You also need experience in a laboratory setting. The biotechnology field is growing quickly, so an entry-level engineer job in the field is perfect for those looking to pursue this a career in this industry.

What is the difference between Bioprocess Engineer vs Process Development Scientist?

AspectBioprocess EngineerProcess Development Scientist
Required CredentialsBachelor's or Master's in Bioengineering, Biotechnology, or related fieldsBachelor's or Master's in Bioengineering, Biotechnology, or related fields
Work EnvironmentManufacturing facilities, production lines, biotech companiesResearch labs, R&D departments, biotech firms
Employer & Industry UsageBiotech, pharmaceutical manufacturing, contract manufacturing organizationsBiotech, pharmaceutical R&D, research institutions
Common Search & ComparisonYesYes

While both roles require similar educational backgrounds and work in biotech environments, Bioprocess Engineers focus on scaling up and optimizing manufacturing processes, whereas Process Development Scientists concentrate on developing and refining processes during early research stages. Understanding these differences helps professionals choose the right career path or job search focus.

What are the key skills and qualifications needed to thrive as a Bioprocess Engineer, and why are they important?

To thrive as a Bioprocess Engineer, you need a strong background in chemical or biochemical engineering, with expertise in cell culture, fermentation, and process optimization, usually backed by a relevant engineering degree. Familiarity with bioprocess simulation software, laboratory automation tools, and regulatory standards like GMP is critical. Strong problem-solving abilities, attention to detail, and effective teamwork are standout soft skills for this role. These competencies ensure efficient development and scaling of bioprocesses, compliance with quality standards, and successful collaboration in biomanufacturing environments.

What are some common challenges faced by Bioprocess Engineers when scaling up production from the lab to industrial levels?

Bioprocess Engineers often encounter challenges when scaling up processes, such as maintaining product quality and consistency, optimizing yield, and ensuring efficient mixing and mass transfer in larger bioreactors. Unexpected issues like contamination risks and differences in process dynamics can arise at larger scales, requiring close collaboration with quality assurance, manufacturing, and R&D teams. Successful scale-up demands strong problem-solving skills, adaptability, and a thorough understanding of both biological and engineering principles.

What does a Bioprocess Engineer do?

A Bioprocess Engineer designs and optimizes processes that use living cells or their components, such as bacteria or enzymes, to produce products like pharmaceuticals, biofuels, and food ingredients. Their work involves scaling up laboratory processes to industrial production, ensuring efficiency, safety, and regulatory compliance. They collaborate with scientists, production teams, and quality assurance to troubleshoot issues and improve yields. Bioprocess Engineers play a critical role in the biotechnology and pharmaceutical industries by bridging the gap between research and manufacturing.
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Bioprocess Engineer jobs near you
Infographic showing various Bioprocess Engineer job openings in the United States as of May 2026, with employment types broken down into 25% Part Time, and 75% Contract. Highlights an 92% Physical, 1% Hybrid, and 7% Remote job distribution, with an average salary of $82,999 per year, or $39.9 per hour.
Bioprocess Engineer

Bioprocess Engineer

Phil Ellis Associates, Inc.

Huntsville, AL • On-site

Full-time

Posted 28 days ago

Job description

Company Description

A fully integrated biopharmaceutical company focused on developing a portfolio of innovative treatments for cancer and infectious diseases using their DNA-mediated gene transfer technologies. 

Job Description

Company is seeking to hire a Bioprocess Engineer to support the company's ongoing development of novel immunotherapies. The position will play an integral role in the establishment of a GMP manufacturing facility to produce plasmid DNA active pharmaceutical ingredient (API).

       Lead the development of pilot scale downstream processing (DSP) unit operations of plasmid DNA from bacterial cell paste (from 10 L - 100 L bioreactor fermentation), to include lysis, clarification, ultrafiltration/diafiltration, and ion exchange chromatography.

       Plan and execute structured process development experiments to achieve the target yield, process optimization, product quality, scale-up and process robustness objectives.

       Play a pivotal role in the establishment of a GMP manufacturing facility to produce plasmid DNA active pharmaceutical ingredient (API).

       Document work thoroughly with a detail-oriented approach, write concise technical reports, and make effective presentations to management and other team members.

       Translate developed processes into standard operating procedures (SOPs) as well as necessary calibration and preventive maintenance SOPs.

       Write validation protocols and lead the technical support staff to successfully execute IQ, OQ, and PQ.

       Lead the process transition into the new facility.

       Troubleshoot, optimize, and improve ongoing process activity with scientific curiosity.

Qualifications

       B.S. or M.S. degree in Biochemical/Chemical Engineering preferred. Will also consider other disciplines such as biology, chemistry, or related field with requisite experience.

       4+ years of hands-on biopharmaceutical experience at pilot or commercial scale with bioreactor fermentation (USP) and DSP of plasmid DNA from bacterial cell paste, including lysis, clarification, ultrafiltration/diafiltration, and ion exchange chromatography.

       2+ years of experience working in a GMP manufacturing environment. Candidates with supervisory experience are preferred.

       Significant experience using ultrafiltration and diafiltration with tangential flow filtration (TFF) in a DSP unit operation.

Additional Information

Competitive salary, bonus, stock, relocation and benefits are offered.

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