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Bioprocess Engineer Jobs in Colorado (NOW HIRING)

Bachelor's degree in Mechanical Engineering, Chemical Engineering, Bioprocess Engineering, or a related engineering discipline from an ABET-accredited program. * 0-3 years of relevant engineering ...

Bachelor's degree in Mechanical Engineering, Chemical Engineering, Bioprocess Engineering, or a related engineering discipline from an ABET-accredited program. * 0-3 years of relevant engineering ...

Bachelor's degree in Mechanical Engineering, Chemical Engineering, Bioprocess Engineering, or a related engineering discipline from an ABET-accredited program. * 0-3 years of relevant engineering ...

Bachelor's in chemical engineering, Biochemical Engineering, or related field * 11+ years of experience in bioprocess development or manufacturing within the biotech or biopharma industry * Expertise ...

Senior Engineer, MS&T

Boulder, CO · On-site

$118K - $178K/yr

Bachelor's in chemical engineering, Biochemical Engineering, or related field * 11+ years of experience in bioprocess development or manufacturing within the biotech or biopharma industry * Expertise ...

Bioprocess Engineer information

See Colorado salary details

$11.6K

$87.3K

$119.3K

How much do bioprocess engineer jobs pay per year?

As of Sep 1, 2026, the average yearly pay for bioprocess engineer in Colorado is $87,275.00, according to ZipRecruiter salary data. Most workers in this role earn between $52,600.00 and $107,800.00 per year, depending on experience, location, and employer.

What is bioprocess engineering?

A bioprocess engineer uses biological materials to create a variety of products. As a bioprocess engineer, you apply your biology and chemistry skills to create foods, products used in the agriculture industry, biofuels, pharmaceuticals, and water filtration systems, among other products. Qualifications for this career depend on the specific duties of a job, but you should obtain at least a bachelor’s degree in biology or chemistry. Most bioprocess engineers go on to pursue a graduate degree as well. You also need experience in a laboratory setting. The biotechnology field is growing quickly, so an entry-level engineer job in the field is perfect for those looking to pursue this a career in this industry.

What does a bioprocess engineer do?

A Bioprocess Engineer designs and optimizes processes that use living cells or their components, such as bacteria or enzymes, to produce products like pharmaceuticals, biofuels, and food ingredients. Their work involves scaling up laboratory processes to industrial production, ensuring efficiency, safety, and regulatory compliance. They collaborate with scientists, production teams, and quality assurance to troubleshoot issues and improve yields. Bioprocess Engineers play a critical role in the biotechnology and pharmaceutical industries by bridging the gap between research and manufacturing.

What are the key skills and qualifications needed to thrive as a bioprocess engineer, and why are they important?

To thrive as a Bioprocess Engineer, you need a strong background in chemical or biochemical engineering, with expertise in cell culture, fermentation, and process optimization, usually backed by a relevant engineering degree. Familiarity with bioprocess simulation software, laboratory automation tools, and regulatory standards like GMP is critical. Strong problem-solving abilities, attention to detail, and effective teamwork are standout soft skills for this role. These competencies ensure efficient development and scaling of bioprocesses, compliance with quality standards, and successful collaboration in biomanufacturing environments.

What are some common challenges faced by bioprocess engineers when scaling up production from the lab to industrial levels?

Bioprocess Engineers often encounter challenges when scaling up processes, such as maintaining product quality and consistency, optimizing yield, and ensuring efficient mixing and mass transfer in larger bioreactors. Unexpected issues like contamination risks and differences in process dynamics can arise at larger scales, requiring close collaboration with quality assurance, manufacturing, and R&D teams. Successful scale-up demands strong problem-solving skills, adaptability, and a thorough understanding of both biological and engineering principles.

What is the difference between Bioprocess Engineer vs Process Development Scientist?

AspectBioprocess EngineerProcess Development Scientist
Required CredentialsBachelor's or Master's in Bioengineering, Biotechnology, or related fieldsBachelor's or Master's in Bioengineering, Biotechnology, or related fields
Work EnvironmentManufacturing facilities, production lines, biotech companiesResearch labs, R&D departments, biotech firms
Employer & Industry UsageBiotech, pharmaceutical manufacturing, contract manufacturing organizationsBiotech, pharmaceutical R&D, research institutions
Common Search & ComparisonYesYes

While both roles require similar educational backgrounds and work in biotech environments, Bioprocess Engineers focus on scaling up and optimizing manufacturing processes, whereas Process Development Scientists concentrate on developing and refining processes during early research stages. Understanding these differences helps professionals choose the right career path or job search focus.

What are popular job titles related to Bioprocess Engineer jobs in Colorado?

For Bioprocess Engineer jobs in Colorado, the most frequently searched job titles are:

Infographic showing various Bioprocess Engineer job openings in Colorado as of August 2026, with employment types broken down into 83% Full Time, and 17% Contract. Highlights an 94% In-person, and 6% Hybrid job distribution, with an average salary of $87,275 per year, or $42 per hour.

Process Engineer I - New Grad

CRB

Denver, CO

Full-time

Re-posted 17 hours ago


Job description

Company Description

At CRB, we design and build some of the most powerful facilities in the world — those that change people's lives.  We are the leading provider of sustainable Engineering, Architecture, Construction and Consulting solutions to the global life sciences and food and beverage industries. Our employees provide best-in-class solutions that drive success and positive change for our clients, our people and our communities. CRB is a privately held company with a rich history of serving clients throughout the world, consistently striving for the highest standard of technical knowledge, creativity and execution.  

Job Description

The Entry-Level Process Engineer focuses on the design and engineering of manufacturing facility and equipment, supporting facility infrastructure and critical utility systems. Typical tasks include execution of engineering calculations including heat transfer and pressure drop calculations. The Entry-Level Process Engineer is responsible for supporting the documentation of the process design scope in coordination with other disciplines. The Entry-Level Process Engineer may support field installation teams and execute construction site observations. This role is expected to work closely with other architects, engineers and designers, as well as other internal and external team members to ensure a coordinated, constructible and complete design.  

Core Activities 

  • Supports the documentation of the process design scope in coordination with other disciplines.  

  • Works closely with other architects, engineers and designers, as well as other internal and external team members to ensure a coordinated, constructible and complete design.  

  • Self-checks own work but communicates often with peers and Supervisor.  

  • Able to work on one or more projects concurrently and manage time effectively. 

  • Solves complex problems under the direction and supervision of a mentor or supervisor 

  • Project work may include all levels of design such as studies, conceptual and schematic design, design development, construction documentation and construction administration.  

  • Works on matters of basic complexity in a support role under the direction of more experienced Process Engineers.  

Engineering deliverables include:  

  • Block and Process Flow Diagrams  

  • User Requirements Specifications  

  • Equipment List  

  • Equipment General Arrangements  

  • Equipment Datasheets  

  • Utility Summary  

  • Piping and Instrumentation Diagrams (P&IDs) 

Qualifications

Required Qualifications

  • Bachelor’s degree in Mechanical Engineering, Chemical Engineering, Bioprocess Engineering, or a related engineering discipline from an ABET-accredited program.
  • 0–3 years of relevant engineering experience through internships, co-ops, research, or professional employment.
  • Basic understanding of engineering principles, calculations, and problem-solving methods.
  • Strong written and verbal communication skills with the ability to collaborate effectively on multidisciplinary project teams.
  • Proficiency in Microsoft Office Suite.

Preferred Qualifications

  • Engineer in Training (EIT) certification or successful completion of the Fundamentals of Engineering (FE) exam.
  • Experience with process design, including material and energy balances, process modeling, and equipment sizing calculations.
  • Knowledge of fluid mechanics, hydraulic modeling, and heat transfer principles.
  • Familiarity with chemistry and/or biochemistry concepts.
  • Experience performing engineering design calculations under the guidance of a licensed engineer.
  • Proficiency in AutoCAD.
  • Familiarity with engineering software applications, including process modeling, design, and calculation tools.

Additional Information

All your information will be kept confidential according to EEO guidelines.

CRB is committed to hiring and retaining a diverse workforce. We are proud to be an Equal Opportunity Employer and it is our policy to provide equal opportunity to all people without regard to race, color, religion, national origin, ancestry, marital status, veteran status, age, disability, pregnancy, genetic information, citizenship status, sex, sexual orientation, gender identity or any other legally protected category. Employment is contingent on background screening.

CRB does not accept unsolicited resumes from search firms or agencies. Any resume submitted to any employee of CRB without a prior written search agreement will be considered unsolicited and the property of CRB. Please, no phone calls or emails.

CRB offers a complete and competitive benefit package designed to meet individual and family needs.

If you are unable to complete this application due to a disability, contact this employer to ask for an accommodation or an alternative application process.