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Senior Bioprocess Engineer Jobs (NOW HIRING)

Senior Bioprocess Engineer

Burlington, MA · On-site

$113K - $156K/yr

As a Senior Bioprocess Engineer at MilliporeSigma, you will play a pivotal role in advancing the performance and application of cutting-edge bioprocessing technologies that directly support the ...

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Senior Bioprocess Engineer, Yeast Manufacturing

Beloit, WI · Hybrid

$89K - $121K/yr

What Makes You the Right Fit * BS/MS in Chemical Engineering or related field is strongly preferred. * Minimum five years of relevant experience, preferably in industrial/biochemical yeast processing ...

New

Job Summary Are you ready to transform innovative bioprocess technologies from laboratory concepts ... The Process R&D organization is seeking a highly motivated scientist or engineer to support the ...

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Senior Bioprocess Engineer information

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$59.5K

$126.6K

$183.5K

How much do senior bioprocess engineer jobs pay per year?

As of Aug 23, 2026, the average yearly pay for senior bioprocess engineer in the United States is $126,557.00, according to ZipRecruiter salary data. Most workers in this role earn between $104,500.00 and $143,500.00 per year, depending on experience, location, and employer.

What is a senior bioprocess engineer?

Senior Bioprocess Engineers are experienced professionals who design, develop, and optimize processes for the production of biological products, such as pharmaceuticals, vaccines, and biofuels. They apply principles of biology, chemistry, and engineering to scale up laboratory processes to industrial production while ensuring quality, efficiency, and regulatory compliance. In addition to technical expertise, they often lead project teams, mentor junior engineers, and collaborate with cross-functional departments to troubleshoot and improve manufacturing workflows.

What are the key skills and qualifications needed to thrive as a senior bioprocess engineer?

To thrive as a Senior Bioprocess Engineer, you need a solid background in chemical or biochemical engineering, experience with bioprocess development, and typically a relevant advanced degree. Familiarity with bioreactor systems, process automation software, and regulatory standards like GMP is essential. Strong problem-solving, project management, and communication skills set top performers apart in this role. These competencies are crucial for optimizing production efficiency, ensuring compliance, and leading multidisciplinary teams in complex biomanufacturing environments.

What are some typical challenges a senior bioprocess engineer faces when scaling up processes from the laboratory to commercial production?

A Senior Bioprocess Engineer often encounters challenges related to maintaining process consistency and product quality during scale-up, as small changes in parameters can have significant impacts at larger volumes. Ensuring compliance with regulatory standards, optimizing yield, and integrating new technologies into existing systems are also common hurdles. Collaboration with cross-functional teams—including quality assurance, manufacturing, and research & development—is essential to address these challenges and ensure smooth technology transfer. Effective troubleshooting, data analysis, and process optimization skills are vital in overcoming these obstacles.

What cities are hiring for Senior Bioprocess Engineer jobs?

Cities with the most Senior Bioprocess Engineer job openings:

What are the most commonly searched types of Bioprocess Engineer jobs?

The most popular types of Bioprocess Engineer jobs are:

Who are the top companies hiring for Senior Bioprocess Engineer jobs?

The top employers for Senior Bioprocess Engineer jobs are:

What states have the most Senior Bioprocess Engineer jobs?

States with the most job openings for Senior Bioprocess Engineer jobs include:

What job categories do people searching Senior Bioprocess Engineer jobs look for?

The top searched job categories for Senior Bioprocess Engineer jobs are:

Infographic showing various Senior Bioprocess Engineer job openings in the United States as of August 2026, with employment types broken down into 94% Full Time, 2% Part Time, and 4% Contract. Highlights an 85% Physical, 6% Hybrid, and 9% Remote job distribution, with an average salary of $126,557 per year, or $60.8 per hour.

$113K - $156K/yr

Full-time

Medical, Retirement, PTO

Posted 2 days ago

New


Job description

Work Your Magic with us!Start your next chapter and join MilliporeSigma.

Ready to explore, break barriers, and discover more? We know you've got big plans - so do we! Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.


Your Role

  • As a Senior Bioprocess Engineer at MilliporeSigma, you will play a pivotal role in advancing the performance and application of cutting-edge bioprocessing technologies that directly support the development of life-saving biologics. Working as a key member of a cross-functional team, you will design and execute laboratory experiments to evaluate new technologies, product prototypes, and application scenarios, translating scientific insight into real-world process solutions.
  • You will define process control strategies and develop optimized recipes and methods that set the standard for product performance. Drawing on your deep expertise in downstream processing, you will monitor industry trends, engage with the scientific community, and represent the organization at conferences to stay at the forefront of bioprocessing innovation.
  • You will communicate your findings through high-quality internal and external publications, application notes, and presentations, establishing yourself as a trusted technical authority. By managing stakeholder relationships and guiding cross-functional decisions, you will directly shape the strategic direction of the team and contribute to outcomes that matter for science, for customers, and for patients worldwide.

Who You Are


Basic / Minimum Qualifications:

  • Experience setting up and executing downstream unit operations, including Chromatography, Normal Flow Filtration, and Tangential Flow Filtration (TFF).
  • Prior experience in analytical methods and high-throughput platforms in the context of downstream process development.
  • PhD in Biological or Chemical Engineering or a related discipline and 2 or more years of experience in bioprocess development, OR a Master of Science in Biological or Chemical Engineering or a related discipline and 3 or more years of experience in bioprocess development, OR a Bachelor of Science in Biological or Chemical Engineering or a related discipline and 5 or more years of experience in bioprocess development.

Preferred Qualifications:

  • Hands-on biotechnology industry experience, including TFF and Depth Filtration.
  • Strong problem-solving and analytical skills, including data modeling, Design of Experiments (DoE), and statistical analysis.
  • Experience with laboratory automation platforms.
  • Familiarity with Good Manufacturing Practice (GMP) environments.
  • Excellent written and verbal communication skills, including the ability to produce application notes, technical reports, and poster presentations.
  • Proven ability to collaborate effectively across teams and with external stakeholders including customers and vendors.
  • Willingness to travel domestically and internationally as required.


Base Pay Range for this position: $ 126,100 - 189,100 $
The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here.


What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!

Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!

Employment Type: FULL_TIME