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Senior Bioprocess Engineer Jobs (NOW HIRING)

ADM

Senior Microbiologist - Decatur, IL

Decatur, IL

$90K - $144K/yr

Senior Microbiologist, Process Micro Team - Decatur, IL - Relocation Assistance AvailableResearch ... EducationBS degree or higher in Microbiology, Molecular Biology, Bioprocess Engineering, Food ...

YMC America Inc

SENIOR ACCOUNT MANAGER

Devens, MA · On-site

$135K - $160K/yr

... YMC America's bioprocess systems business. This role develops and executes territory growth ... The Senior Account Manager partners closely with engineering, applications, project management, and ...

New

YMC America Inc

SENIOR ACCOUNT MANAGER

Devens, MA · On-site

$135K - $160K/yr

... YMC America's bioprocess systems business. This role develops and executes territory growth ... The Senior Account Manager partners closely with engineering, applications, project management, and ...

New

Danaher

VP, Bioprocess Sales Americas (Remote)

$275K - $325K/yr

Act as a senior external representative of Cytiva, strengthening executive-level customer ... Bachelor's degree in Life Sciences, Engineering, Business or related field (Master's or MBA ...

Validation & Engineering Group, Inc

PR

$89K - $122K/yr

Process Development Sr Scientist Education: * Doctorate (PhD, PharmD, or MD) with relevant ... A degree in Mechanical Engineering, Chemical Engineering, Biomedical Engineering, Bioprocess ...

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Senior Bioprocess Engineer information

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$59.5K

$126.6K

$183.5K

How much do senior bioprocess engineer jobs pay per year?

As of Aug 13, 2026, the average yearly pay for senior bioprocess engineer in the United States is $126,557.00, according to ZipRecruiter salary data. Most workers in this role earn between $104,500.00 and $143,500.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a senior bioprocess engineer?

To thrive as a Senior Bioprocess Engineer, you need a solid background in chemical or biochemical engineering, experience with bioprocess development, and typically a relevant advanced degree. Familiarity with bioreactor systems, process automation software, and regulatory standards like GMP is essential. Strong problem-solving, project management, and communication skills set top performers apart in this role. These competencies are crucial for optimizing production efficiency, ensuring compliance, and leading multidisciplinary teams in complex biomanufacturing environments.

What are some typical challenges a senior bioprocess engineer faces when scaling up processes from the laboratory to commercial production?

A Senior Bioprocess Engineer often encounters challenges related to maintaining process consistency and product quality during scale-up, as small changes in parameters can have significant impacts at larger volumes. Ensuring compliance with regulatory standards, optimizing yield, and integrating new technologies into existing systems are also common hurdles. Collaboration with cross-functional teams—including quality assurance, manufacturing, and research & development—is essential to address these challenges and ensure smooth technology transfer. Effective troubleshooting, data analysis, and process optimization skills are vital in overcoming these obstacles.

What is a senior bioprocess engineer?

Senior Bioprocess Engineers are experienced professionals who design, develop, and optimize processes for the production of biological products, such as pharmaceuticals, vaccines, and biofuels. They apply principles of biology, chemistry, and engineering to scale up laboratory processes to industrial production while ensuring quality, efficiency, and regulatory compliance. In addition to technical expertise, they often lead project teams, mentor junior engineers, and collaborate with cross-functional departments to troubleshoot and improve manufacturing workflows.

What cities are hiring for Senior Bioprocess Engineer jobs?

Cities with the most Senior Bioprocess Engineer job openings:

What are the most commonly searched types of Bioprocess Engineer jobs?

The most popular types of Bioprocess Engineer jobs are:

Who are the top companies hiring for Senior Bioprocess Engineer jobs?

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Senior Bioprocess Engineer jobs near you
Infographic showing various Senior Bioprocess Engineer job openings in the United States as of August 2026, with employment types broken down into 92% Full Time, 2% Part Time, and 6% Contract. Highlights an 86% Physical, 5% Hybrid, and 9% Remote job distribution, with an average salary of $126,557 per year, or $60.8 per hour.

Principal Scientist - BioProcess Development

Wacker Chemie AG

San Diego, CA • On-site

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 14 days ago

Job description

Job Title: Principal Scientist - BioProcess Development
Job Location (Short): San Diego, CA, USA, 92121
Posting Start Date: 4/29/26
Do you want to take responsibility and make a difference with your work? With your expertise, we can achieve great goals together. We are WACKER - Reliable. Determined. Ambitious. As one of the world's most research-intensive chemical companies, we've been making countless products that are an integral part of your everyday life possible for over 100 years. From vegan food to resource-efficient buildings to solar cells, we develop sustainable solutions that change the future.
To strengthen our team in San Diego,
we are looking for you as a(n) Principal Scientist - BioProcess Development.
The Principal Scientist, BioProcess Development is a senior technical leadership role responsible for the design, development, optimization, and scale-up of bioprocesses for plasmid DNA, protein biologics, and emerging modalities. This position serves as a scientific authority and technical project lead, bridging hands-on process development with strategic program execution. The Principal Scientist independently leads complex development programs, drives platform and technology innovation, and ensures successful technology transfer to Manufacturing and MSAT.
  • Lead complex upstream/downstream bioprocess development programs. Act as technical escalation point for complex process, scale up, and manufacturability challenges across development programs.
  • Serve as technical project lead and define development strategies aligned with client requirements and timelines, regulatory phase, and manufacturing constraints. Ensure development activities comply with EHS, quality, and data integrity requirements.
  • Design scalable processes using QbD principles. Evaluate and implement new technologies, materials, and unit operations to improve yield, robustness, and cost of goods. Drive process characterization, process definition, and comparability studies in support of process changes or scale transitions.
  • Author and review development protocols, development SOPs, development reports, technical documentation, and tech transfer documentation. Support technical presentations/publications.
  • Coordinate tech transfer with Manufacturing, QC, and MSAT. Review and provide critical input to batch records, development protocols, and technical instructions supporting GMP execution. Partner with MSAT and Manufacturing to support process validation readiness and late stage development activities, as needed. Support root cause investigations and CAPA development for process related deviations impacting development or manufacturing.
  • Support RFPs and customer technical discussions. Support client onboarding and technical due diligence, including assessment of incoming processes and data packages.
  • Provide technical mentorship. Contribute to technical governance forums, development reviews, or internal scientific committees.
  • Provide scientific input to cost modeling, process economics, and capacity planning discussions. Represent Process Development in cross functional decision making related to program strategy, timelines, and risk.
  • Contribute to platform and continuous improvement initiatives. Champion standardization, platform processes, and best practices while maintaining flexibility for client-specific needs

Position Requirements:
  • Bachelor of Science degree in Biochemistry, Biological Sciences, Bioengineering, Chemistry, or related scientific discipline; Master's Degree or PhD in Biology, Chemistry, Engineering or related scientific field is preferred.
  • Minimum 10 years of relevant experience with 5 years in Contract Development and Manufacturing services of Biopharmaceuticals.
  • Experience in Plasmid and Protein development and/or manufacturing is required. Additional experience in RNA, LNP preferred.
  • Ability to travel up to 10%.
  • Experience in and good technical knowledge of biotherapeutic process development and manufacturing is required. Proven track record of independent decision making on complex technical issues with appropriate risk assessment and escalation. High level of scientific accountability and ownership, with a proactive approach to problem solving.
  • In-depth knowledge in upstream fermentation process development and downstream purification development to support development of pipeline projects, platforms, and innovative technologies.
  • Strong analytical skills with experience in process mapping and process design.
  • Proficiency in data analysis and performance measurement tools.
  • Demonstrated ability to operate effectively in a client facing CDMO environment, balancing scientific rigor, timelines, and customer expectations. Ability to clearly communicate complex technical concepts to diverse audiences, including non technical stakeholders and clients.
  • Extensive experience as a project lead for biologics pipeline programs. Strong capability in managing evolving timelines, program risks and mitigation strategies. Strong understanding of phase appropriate development, including early stage, clinical, and commercial readiness considerations.
  • Experience supporting or leading technical due diligence, feasibility assessments, and program onboarding activities. Comfortable contributing to proposal development, technical justifications, and cost/scope discussions.
  • Innovative mind-set demonstrated by technical accomplishments, external presentations, and publications is a plus. Commitment to maintaining awareness of emerging technologies, regulatory trends, and competitive landscape relevant to bioprocess development.
  • Knowledge in authoring and providing critical input to the regulatory submissions including but not limited to Investigational New Drugs, Investigational Medicinal Product Dossiers, and Clinical Trial Applications is a plus.
  • Ability to work closely with cross-functional stakeholders to ensure team alignment with functional objectives. Ability to manage ambiguity and rapidly evolving priorities across multiple client programs and internal initiatives.
  • Ability to lead technically without direct authority. Demonstrated ability to mentor and elevate technical capability of junior scientists through coaching, review, and example.
  • Strong collaboration skills in matrixed and cross functional organizations, including global or multi-site teams. Willingness to support occasional nonstandard work hours to meet critical project milestones.

The anticipated salary range for candidates who will work in San Diego is $140,000 - $155,000. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the job, type and length of experience within the industry, education, etc . Wacker is a multi-state employer and this salary range may not reflect positions that work in other states.
What do we offer?
WACKER strives to reward its employees in a fair and equitable manner. Our Total Rewards Package considers employee wellbeing and is comprised of compensation, benefits, work-life balance, performance & recognition, and career development.
  • Compensation and Incentive plans
  • Medical, Dental, and Vision Insurance effective day 1
  • Paid Time Off in addition to personal days and holidays
  • Paid parental leave
  • Wellbeing fund
  • Flexible hybrid work arrangements
  • 401(k) with company match
  • Education Assistance Program
  • Career development and advancement opportunities
  • Support for Community Involvement

We are looking forward to your online application at www.wacker.com.
Reference Code: 30937
The information contained herein is not intended to be an all-inclusive list of the duties and responsibilities of the job, nor are they intended to be an all-inclusive list of the skills and abilities required to do the job. A minimum requirement for this US-based position is the ability to work legally in the United States on a permanent unrestricted basis. Visa sponsorship is not available for this position, including any type of US permanent residency (e.g., for a green card).
Wacker is an Equal Opportunity Employer. We actively promote the equality of opportunity for all who are qualified and bring the requisite experience, talent, skill and potential, without regard to age, disability, sex, race, religion or belief, marriage/civil partnership, pregnancy/maternity, sexual orientation, or any other protected characteristics. We welcome all applications from a wide range of candidates. Selection for roles will be based on individual merit alone.

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