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Bioprocess Engineer Jobs (NOW HIRING)

Biosphere

Open Application

Oakland, CA · On-site

Whether your background is in bioprocess engineering, synthetic biology, automation, operations, manufacturing, business development, or something unexpected, please reach out. Who We're Looking For

Biosphere

Open Application

Oakland, CA · On-site

Whether your background is in bioprocess engineering, synthetic biology, automation, operations, manufacturing, business development, or something unexpected, please reach out. Who We're Looking For

UPSIDE Foods

Scientist II, MSAT

Emeryville, CA

The ideal candidate brings a strong foundation in bioprocess engineering and a willingness to operate at the interface of PD and Manufacturing, contributing to both experimental development and on ...

Dakota BioWorx

Client Project Manager

Brookings, SD · On-site

Bachelor of Science in a bioprocess-related discipline such as chemical engineering, microbiology, biotechnology, bioprocess engineering OR equivalent/similar experience * Experience in bioprocessing ...

Bayer Inc.

Principal Process Engineer

Berkeley, CA · On-site +1

$128K - $192K/yr

In this role, you support the delivery of bioprocess equipment technologies to Bayer's global ... Engineering degree or equivalent; Chemical Engineering preferred; * Professional registration and ...

Bayer

Principal Process Engineer

Berkeley, CA · On-site +1

$128K - $192K/yr

Principal Process Engineer As a Principal Process Engineer, you are accountable for the definition ... In this role, you support the delivery of bioprocess equipment technologies to Bayer's global ...

Bayer

Principal Process Engineer

Berkeley, CA · On-site

$128K - $192K/yr

In this role, you support the delivery of bioprocess equipment technologies to Bayer's global ... Engineering degree or equivalent; Chemical Engineering preferred; * Professional registration and ...

Invert

Solutions Engineer

San Francisco, CA · Remote

Bioprocess data is high-frequency, multi-source, and scattered across systems that rarely talk to ... Help shape what Solutions Engineering looks like at Invert as we grow What you\'ll bring * 5-8 ...

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Bioprocess Engineer information

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How much do bioprocess engineer jobs pay per year?

As of Jun 9, 2026, the average yearly pay for bioprocess engineer in the United States is $82,999.00, according to ZipRecruiter salary data. Most workers in this role earn between $50,000.00 and $102,500.00 per year, depending on experience, location, and employer.

What Is Bioprocess Engineering?

A bioprocess engineer uses biological materials to create a variety of products. As a bioprocess engineer, you apply your biology and chemistry skills to create foods, products used in the agriculture industry, biofuels, pharmaceuticals, and water filtration systems, among other products. Qualifications for this career depend on the specific duties of a job, but you should obtain at least a bachelor’s degree in biology or chemistry. Most bioprocess engineers go on to pursue a graduate degree as well. You also need experience in a laboratory setting. The biotechnology field is growing quickly, so an entry-level engineer job in the field is perfect for those looking to pursue this a career in this industry.

What is the difference between Bioprocess Engineer vs Process Development Scientist?

AspectBioprocess EngineerProcess Development Scientist
Required CredentialsBachelor's or Master's in Bioengineering, Biotechnology, or related fieldsBachelor's or Master's in Bioengineering, Biotechnology, or related fields
Work EnvironmentManufacturing facilities, production lines, biotech companiesResearch labs, R&D departments, biotech firms
Employer & Industry UsageBiotech, pharmaceutical manufacturing, contract manufacturing organizationsBiotech, pharmaceutical R&D, research institutions
Common Search & ComparisonYesYes

While both roles require similar educational backgrounds and work in biotech environments, Bioprocess Engineers focus on scaling up and optimizing manufacturing processes, whereas Process Development Scientists concentrate on developing and refining processes during early research stages. Understanding these differences helps professionals choose the right career path or job search focus.

What are the key skills and qualifications needed to thrive as a Bioprocess Engineer, and why are they important?

To thrive as a Bioprocess Engineer, you need a strong background in chemical or biochemical engineering, with expertise in cell culture, fermentation, and process optimization, usually backed by a relevant engineering degree. Familiarity with bioprocess simulation software, laboratory automation tools, and regulatory standards like GMP is critical. Strong problem-solving abilities, attention to detail, and effective teamwork are standout soft skills for this role. These competencies ensure efficient development and scaling of bioprocesses, compliance with quality standards, and successful collaboration in biomanufacturing environments.

What are some common challenges faced by Bioprocess Engineers when scaling up production from the lab to industrial levels?

Bioprocess Engineers often encounter challenges when scaling up processes, such as maintaining product quality and consistency, optimizing yield, and ensuring efficient mixing and mass transfer in larger bioreactors. Unexpected issues like contamination risks and differences in process dynamics can arise at larger scales, requiring close collaboration with quality assurance, manufacturing, and R&D teams. Successful scale-up demands strong problem-solving skills, adaptability, and a thorough understanding of both biological and engineering principles.

What does a Bioprocess Engineer do?

A Bioprocess Engineer designs and optimizes processes that use living cells or their components, such as bacteria or enzymes, to produce products like pharmaceuticals, biofuels, and food ingredients. Their work involves scaling up laboratory processes to industrial production, ensuring efficiency, safety, and regulatory compliance. They collaborate with scientists, production teams, and quality assurance to troubleshoot issues and improve yields. Bioprocess Engineers play a critical role in the biotechnology and pharmaceutical industries by bridging the gap between research and manufacturing.
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Bioprocess Engineer jobs near you
Infographic showing various Bioprocess Engineer job openings in the United States as of May 2026, with employment types broken down into 25% Part Time, and 75% Contract. Highlights an 92% Physical, 1% Hybrid, and 7% Remote job distribution, with an average salary of $82,999 per year, or $39.9 per hour.

Senior Scientist / Principal Scientist, Bioprocess Sciences

Pivotal Life Sciences

San Diego, CA • On-site

$120K - $190K/yr

Full-time

Posted 17 days ago

Job description

Title: Senior Scientist / Principal Scientist, Bioprocess Sciences
Location: San Diego
Job Type: Full-Time
About Us: A stealth-mode biotech focused on developing best-in-class delivery for in vivo gene editing.
Job Summary: We are seeking a highly motivated and experienced scientific expert to join our team as a Senior Scientist or Principal Scientist of Bioprocess Sciences. This role will provide technical expertise for bacterial protein production programs supporting research and development. The successful candidate will be part of a dynamic team of scientists responsible for process development, scale-up strategy and external manufacturing oversight. Title and compensation will be commensurate with experience.
Key Responsibilities:
  • Provide technical expertise for bacterial strain engineering, fermentation, protein expression, purification, and protein characterization activities.
  • Develop, optimize, and scale bacterial culture and purification processes for internal and external manufacturing.
  • Manage and oversee activities at contract development and manufacturing organizations (CDMOs), including tech transfer, process troubleshooting, timelines, and deliverables.
  • Partner cross-functionally with research, analytical, quality, and leadership teams to achieve project milestones.
  • Establish and maintain robust documentation, protocols, and data packages to support internal decision-making and external partners.
  • Prepare and present technical reports, development strategies, and risk assessments to internal stakeholders.
  • Stay current with advancements in bioprocessing technologies, manufacturing trends, and regulatory expectations.

Qualifications:
  • D. degree in Chemistry, Biology, Biochemistry, Biomedical Engineering, Chemical Engineering, or a related field.
  • 6+ years of progressive experience in bacterial protein expression, purification, and bioprocess development.
  • Demonstrated experience leading projects and mentoring or managing scientists.
  • Hands-on expertise with affinity-based protein purification (e.g., FPLC), bacterial expression systems, and routine molecular biology assays.
  • Strong working knowledge of SDS-PAGE, Western blotting, ELISA, and other biochemical and biophysical assays.
  • Experience interpreting QC assays (fluorometric, chromogenic, etc.) and assessing data quality and process performance.
  • Routine use of electronic laboratory notebooks (e.g., Benchling) with a strong commitment to data integrity.
  • Excellent analytical, communication, and organizational skills with the ability to manage multiple priorities.
  • Ability to work independently in a fast-paced, evolving environment.

Preferred Qualifications:
  • Direct experience managing or collaborating with CDMOs for process development or manufacturing.
  • Experience with bioreactor operations, scale-up, and tech transfer.
  • Protein characterization experience using HPLC/UPLC and/or LC-MS.
  • Familiarity with regulatory expectations related to bioprocessing and manufacturing.
  • Background in protein engineering or recombinant protein production.

Benefits:
  • Competitive salary, equity, and comprehensive benefits package.
  • Opportunities for professional growth and leadership development.
  • Fast-paced, collaborative, and innovative work environment.

How to Apply: Interested candidates should submit their resume and a cover letter detailing relevant experience. To be considered for the role, applicants must be:
  • Eligible to work in the United States for any employer without sponsorship.
  • Able to work onsite in the lab located in San Diego.
  • A direct candidate and not from a third party, i.e., staffing agency.

Apply