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Trial Master File Manager Jobs (NOW HIRING)

Medpace, Inc.

Trial Master File Specialist

Cincinnati, OH ยท On-site

$32.25 - $44/hr

The Trial Master File (TMF) is a collection of documents that stores all data and research ... It is an integral tool and helps teams manage trials more effectively. TMF oversight is important ...

GQR

Associate Director Trial Master File

Santa Rosa, CA

$36.75 - $50/hr

Associate Director, Trial Master File (TMF) Position Summary The Associate Director, Trial Master ... Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or ...

GQR

Associate Director Trial Master File

San Francisco, CA ยท On-site

$39.50 - $54/hr

Associate Director, Trial Master File (TMF) Position Summary The Associate Director, Trial Master ... Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or ...

GQR

Associate Director Trial Master File

Sonoma, CA

$37.50 - $51.25/hr

Associate Director, Trial Master File (TMF) Position Summary The Associate Director, Trial Master ... Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or ...

GQR

Associate Director Trial Master File

San Jose, CA

$39.25 - $53.50/hr

Associate Director, Trial Master File (TMF) Position Summary The Associate Director, Trial Master ... Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or ...

GQR

Associate Director Trial Master File

Sunnyvale, CA

$39.75 - $54.50/hr

Associate Director, Trial Master File (TMF) Position Summary The Associate Director, Trial Master ... Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or ...

GQR

Associate Director Trial Master File

Hayward, CA

$38.50 - $52.50/hr

Associate Director, Trial Master File (TMF) Position Summary The Associate Director, Trial Master ... Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or ...

GQR

Associate Director Trial Master File

Alameda, CA

$38.75 - $53/hr

Associate Director, Trial Master File (TMF) Position Summary The Associate Director, Trial Master ... Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or ...

GQR

Associate Director Trial Master File

Santa Clara, CA ยท On-site

$39 - $53.25/hr

Associate Director, Trial Master File (TMF) Position Summary The Associate Director, Trial Master ... Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or ...

GQR

Associate Director Trial Master File

Fremont, CA

$36.75 - $50/hr

Associate Director, Trial Master File (TMF) Position Summary The Associate Director, Trial Master ... Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or ...

GQR

Associate Director Trial Master File

Mundelein, IL

$34.25 - $46.75/hr

Associate Director, Trial Master File (TMF) Position Summary The Associate Director, Trial Master ... Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or ...

GQR

Associate Director Trial Master File

San Mateo, CA

$38.25 - $52/hr

Associate Director, Trial Master File (TMF) Position Summary The Associate Director, Trial Master ... Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or ...

Medpace, Inc.

Trial Master File Specialist

Cincinnati, OH

$32.25 - $44/hr

The Trial Master File (TMF) is a collection of documents that stores all data and research ... It is an integral tool and helps teams manage trials more effectively. TMF oversight is important ...

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Trial Master File Manager information

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$44.5K

$75.6K

$114K

How much do trial master file manager jobs pay per year?

As of Jun 20, 2026, the average yearly pay for trial master file manager in the United States is $75,583.00, according to ZipRecruiter salary data. Most workers in this role earn between $55,500.00 and $93,500.00 per year, depending on experience, location, and employer.

What are some common challenges faced by Trial Master File Managers, and how can they be addressed?

Trial Master File Managers often encounter challenges such as ensuring TMF completeness, maintaining regulatory compliance, and coordinating document submissions across multiple stakeholders. Keeping documents up-to-date and audit-ready requires strong attention to detail and effective communication with clinical teams, vendors, and sponsors. Leveraging electronic TMF systems, implementing standardized processes, and promoting regular training can help address these challenges and ensure the integrity of the TMF throughout a study.

What is a Trial Master File Manager?

A Trial Master File Manager is a professional responsible for overseeing the creation, maintenance, and quality control of the Trial Master File (TMF) in clinical research. The TMF is a collection of essential documents that allow the conduct of a clinical trial to be reconstructed and evaluated. The manager ensures that all documents are complete, accurate, and compliant with regulatory requirements throughout the trial's lifecycle. They work closely with clinical teams, auditors, and regulatory authorities to guarantee readiness for inspections and audits. Their role is crucial for maintaining transparency and credibility in clinical research processes.

What are the key skills and qualifications needed to thrive as a Trial Master File Manager, and why are they important?

To thrive as a Trial Master File Manager, you typically need a strong background in clinical research, regulatory requirements, and document management, often supported by a degree in life sciences or a related field. Familiarity with electronic Trial Master File (eTMF) systems, GCP guidelines, and relevant industry certifications like DIA's TMF Professional Certification is important. Attention to detail, organizational skills, and effective communication help ensure TMF integrity and coordination across cross-functional teams. These skills are crucial for maintaining regulatory compliance, audit readiness, and efficient clinical trial operations.
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Trial Master File Manager jobs near you
Infographic showing various Trial Master File Manager job openings in the United States as of June 2026, with employment types broken down into 100% Full Time. Highlights an 100% Remote job distribution, with an average salary of $75,583 per year, or $36.3 per hour.