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Senior Process Engineer Jobs in Indiana (NOW HIRING)

Job Title: Sr. Chemical Process Engineer Company: X-Bow Systems Location: Crane, IN Position Type: Full-Time About Us: X-Bow Systems is a cutting-edge aerospace technology company focused on ...

New

Job Title: Sr. Chemical Process Engineer Company: X-Bow Systems Location: Crane, IN Position Type: Full-Time About Us: X-Bow Systems is a cutting-edge aerospace technology company focused on ...

New

Job Title: Sr. Chemical Process Engineer Company: X-Bow Systems Location: Crane, IN Position Type: Full-Time About Us: X-Bow Systems is a cutting-edge aerospace technology company focused on ...

Job Title: Sr. Chemical Process Engineer Company: X-Bow Systems Location: Crane, INPosition Type: Full-TimeAbout Us: X-Bow Systems is a cutting-edge aerospace technology company focused on ...

Process Engineer

Indianapolis, IN

$75K - $105K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Please note that we are seeking a senior team member with at least 7 years of aerospace engineering experience. Essential Job Functions: * Develop written processes in accordance with customer ...

Process Engineer

Indianapolis, IN ยท On-site

$75K - $105K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Please note that we are seeking a senior team member with at least 7 years of aerospace engineering experience. Essential Job Functions: * Develop written processes in accordance with customer ...

Process Engineer

Indianapolis, IN ยท On-site

  • Medical

  • Dental

  • Vision

  • Retirement

Process Engineer Location: Indianapolis, IN Reports To: Manager Process Engineering Workplace Type: Onsite Ingredion is hiring a Process Engineer to provide technical support and leadership to the ...

Process Engineer

Bloomington, IN ยท On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

We are looking for a Process Engineer (level depends on experience) that is responsible for ... This position is 100% onsite at the Bloomington facility and reports directly to the Sr. Manager ...

Process Engineer

Bloomington, IN ยท On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

We are looking for a Process Engineer (level depends on experience) that is responsible for ... This position is 100% onsite at the Bloomington facility and reports directly to the Sr. Manager ...

Process Engineer

Indianapolis, IN ยท On-site

  • Medical

  • Dental

  • Vision

  • Retirement

Process Engineer Location: Indianapolis, IN Reports To: Manager Process Engineering Workplace Type: Onsite Ingredion is hiring a Process Engineer to provide technical support and leadership to the ...

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Process Engineer

Plainfield, IN ยท On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

The Process Engineer plays a critical role in supporting engineering and production teams to ensure the successful introduction, validation, and continuous improvement of manufacturing processes.

Showing results 21-40

Senior Process Engineer information

See Indiana salary details

$71.4K

$115.3K

$162.2K

How much do senior process engineer jobs pay per year?

As of Aug 17, 2026, the average yearly pay for senior process engineer in Indiana is $115,250.00, according to ZipRecruiter salary data. Most workers in this role earn between $99,000.00 and $128,000.00 per year, depending on experience, location, and employer.

What is the difference between Senior Process Engineer vs Process Engineer?

AspectSenior Process EngineerProcess Engineer
QualificationsBachelor's or Master's in Engineering, often with 5+ years experienceBachelor's degree in Engineering or related field, typically 1-3 years experience
ResponsibilitiesLeading process improvements, mentoring, project managementSupporting process development, data analysis, assisting senior staff
Work EnvironmentDesign teams, manufacturing plants, R&D departmentsManufacturing facilities, engineering teams, operational support

Senior Process Engineers typically have more experience, leadership duties, and oversee complex projects, while Process Engineers focus on supporting process development and implementation. Both roles are essential in manufacturing and engineering industries, but the senior role involves greater responsibility and strategic planning.

What are the key skills and qualifications needed to thrive as a senior process engineer?

To thrive as a Senior Process Engineer, you need a strong background in chemical or process engineering, problem-solving skills, and typically a bachelor's or master's degree in a relevant field. Expertise in process simulation software (such as Aspen Plus or HYSYS), Six Sigma or Lean certifications, and familiarity with process control systems are highly valued. Outstanding analytical abilities, leadership, and effective communication set top performers apart in this role. These skills and qualifications are crucial for optimizing processes, ensuring safety and compliance, and leading teams to achieve operational excellence.

What does a senior process engineer do?

A Senior Process Engineer is responsible for designing, optimizing, and overseeing processes within manufacturing or production environments. They analyze workflows, troubleshoot issues, and implement improvements to increase efficiency, safety, and product quality. Senior Process Engineers often lead projects, mentor junior engineers, and collaborate with cross-functional teams to ensure operational excellence. Their expertise is vital in industries like chemicals, pharmaceuticals, oil and gas, and food processing.

How much does a senior process engineer earn?

A senior process engineer typically earns between $80,000 and $130,000 annually, depending on experience, industry, and location. They often have specialized skills in process optimization, project management, and may hold certifications like Six Sigma or PE licensure.

What are some common challenges senior process engineers face when working on cross-functional teams?

Senior Process Engineers often collaborate with professionals from various departments, such as operations, quality, and maintenance. A common challenge is aligning diverse priorities and communication styles to achieve shared project goals. Successfully managing these differences requires strong interpersonal and project management skills, as well as the ability to translate technical concepts for non-engineering colleagues. Regular meetings and clear documentation can help ensure everyone stays informed and engaged throughout the process.

What are the most commonly searched types of Process Engineer jobs in Indiana?

The most popular types of Process Engineer jobs in Indiana are:

What job categories do people searching Senior Process Engineer jobs in Indiana look for?

The top searched job categories for Senior Process Engineer jobs in Indiana are:

What cities in Indiana are hiring for Senior Process Engineer jobs?

Cities in Indiana with the most Senior Process Engineer job openings:

Infographic showing various Senior Process Engineer job openings in Indiana as of August 2026, with employment types broken down into 1% As Needed, 78% Full Time, 16% Part Time, 4% Contract, and 1% Nights. Highlights an 93% Physical, 2% Hybrid, and 5% Remote job distribution, with an average salary of $115,250 per year, or $55.4 per hour.

Senior Process Engineer, Lilly Medicine Foundry

Initial Therapeutics, Inc.

Indianapolis, IN โ€ข On-site

$66 - $172/hr

Other

Medical, Dental, Vision, Life, Retirement, PTO

Posted 8 hours ago

Posted today


Job description

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver lifeโ€‘changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless workโ€”but itโ€™s work worth doing. If youโ€™re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring lifeโ€‘changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. Weโ€™re looking for people who are determined to make life better for people around the world.

About the Lilly Medicine Foundry

Lilly recently announced a $4.5 billion investment to create the Lilly Medicine Foundry, a new center for advanced manufacturing and drug development. The firstโ€‘ever facility of its kind, combining research and manufacturing in a single location, the Medicine Foundry will allow Lilly to further develop innovative solutions to optimize manufacturing processes and increase capacity for clinical trial medicines, while also reducing costs and environmental impact.

Organizational Overview

Lilly is currently constructing an advanced research facility for production of API molecules for clinical trials located in Lebanon, IN. This facility is Lillyโ€™s largest investment in a clinical trial manufacturing capacity and is intended to provide APIs for current and future products, including new modalities. This is a unique opportunity to be a part of the startup team for a greenfield manufacturing site, and the successful candidate will help to build the processes and facility to enable a successful startup into GMP manufacturing operations.

We are seeking a small molecule Process Engineer to support the pilot plant facility in Lebanon with a focus on active pharmaceutical ingredient synthesis. This position involves solving technical challenges with equipment design, developing and sustaining process knowledge, optimizing processes, and managing equipment capabilities.

Responsibilities
  • Perform impact and risk assessments for unit operations
  • Learn the lab and plant design for the reactors including automation recipes and procedures.
  • Ensure that people and their environment are safe and that company policies concerning safety are followed.
  • Ensure processing equipment remains compliant with internal Quality System requirements, applicable engineering standards, and cGMP requirements.
  • Assess rig fit by receiving the technical data package for new processes and performing modeling, simulations and/or experimental work as required to ensure heat and mass transfer are acceptable when scaling to the plant.
  • Active engagement and communication with: HSE, Quality Assurance, Tech Services, Development, Operations, FUME/CQ, Automation, Maintenance, Environmental Monitoring, and Manufacturing.
  • Author, review, or approve highโ€‘quality technical reports and regulatory submissions dealing with the work performed by the department. Ensure that records and technical notebooks are adequately maintained.
  • Demonstrate engagement and employ a quality approach in all endeavors by proactively identifying quality issues and communicating appropriately.
  • Develop or review plans and timetables for project work.
Basic Requirements
  • BS or MS in Chemical Engineering or related engineering degree
  • Minimum of 2 years of experience within a pharmaceutical, biotech, chemical manufacturing, or CMO environment or other relevant batch manufacturing process.
  • Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1.
Additional Preferences
  • Supported manufacturing and/or development activities for active pharmaceutical ingredients, intermediates, or other chemicals
  • Deep technical interest and understanding in the field of Chemical Engineering
  • Familiarity with unit operations including but not limited to chemical reactions, distillation, phase separation, filtration, drying
  • Ability to work well in a team environment incorporating a variety of functional relationships and desire to be point of accountability
  • Experience with any of the following software packages: DeltaV, Dynochem, Aspen, and/or electronic lab notebooks
  • Strong analytical and problemโ€‘solving skills
  • Strong oral and written communication skills for a diverse audience, e.g., both operations staff and management.
  • Ability to work on own initiative and as part of a Process Team consisting of a diverse group of management, production, science and engineering professionals
  • Understanding of process control systems
  • Creativity to identify improvement opportunities and the tenacity/initiative to see them implemented
  • Guidance/mentoring of others through processesFlexibility to meet business needs
Other Information
  • Initial location at Parkwood West, Indianapolis.
  • Permanent location at the new Lilly Medicines Foundry in Lebanon, Indiana.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

#WeAreLilly

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

#Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Womenโ€™s Initiative for Leading at Lilly (WILL).

Actual compensation will depend on a candidateโ€™s education, experience, skills, and geographic location. The anticipated wage for this position is

$66,000 - $171,600

Fullโ€‘time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and wellโ€‘being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities). Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lillyโ€™s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

#WeAreLilly

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