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Senior Cra Jobs in Raleigh, NC (NOW HIRING)

IQVIA

Senior Global Clinical Study Manager

Durham, NC · On-site

Support CRA and team training on therapeutic areas and study-specific needs * Foster collaboration, knowledge sharing, and continuous improvement Qualifications Required * Bachelor's degree in life ...

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Senior Cra information

See Raleigh, NC salary details

$35K

$91.7K

$139.5K

How much do senior cra jobs pay per year?

As of Aug 9, 2026, the average yearly pay for senior cra in Raleigh, NC is $91,681.00, according to ZipRecruiter salary data. Most workers in this role earn between $60,800.00 and $124,400.00 per year, depending on experience, location, and employer.

Is it hard to get a senior CRA job?

Securing a senior Clinical Research Associate (CRA) position can be competitive, often requiring several years of experience in clinical trials, strong knowledge of Good Clinical Practice (GCP), and relevant certifications. Candidates with a proven track record in monitoring, regulatory compliance, and familiarity with clinical trial management systems tend to have better prospects.

How does a senior clinical research associate (CRA) typically collaborate with site staff and project teams during a clinical trial?

A Senior CRA regularly works with site staff, including investigators and coordinators, to ensure clinical trials are conducted according to protocol, regulatory requirements, and Good Clinical Practice (GCP) guidelines. They serve as a key liaison, communicating study updates, addressing site concerns, and providing training when needed. Additionally, Senior CRAs often collaborate with project managers, data managers, and other CRAs to monitor progress, resolve issues, and ensure data integrity. This teamwork is critical for maintaining study timelines and overall trial quality.

What is the difference between Senior Cra vs Clinical Research Associate?

AspectSenior CraClinical Research Associate
Required CredentialsBachelor's degree, experience in clinical trials, often some certificationsBachelor's degree, entry-level to mid-level experience, some certifications
Work EnvironmentLeads monitoring activities, manages sites, mentors junior staffPerforms site monitoring, data collection, and compliance checks
Employer & Industry UsagePharmaceutical companies, CROs, biotech firmsPharmaceutical companies, CROs, biotech firms

The main difference between a Senior Cra and a Clinical Research Associate is experience level and responsibilities. Senior Cras typically oversee monitoring activities, mentor junior staff, and handle more complex tasks, while Clinical Research Associates focus on site monitoring and data collection. Both roles are essential in clinical trials and share similar industry environments and credentials.

What are the key skills and qualifications needed to thrive as a senior clinical research associate (CRA), and why are they important?

To thrive as a Senior Clinical Research Associate, you need deep knowledge of clinical trial protocols, regulatory guidelines (such as GCP), and several years of hands-on experience in clinical monitoring. Familiarity with electronic data capture (EDC) systems, CTMS platforms, and certifications like ACRP or SOCRA are commonly required. Excellent organizational skills, attention to detail, and effective communication are soft skills that set top candidates apart. These skills ensure trial integrity, regulatory compliance, and smooth collaboration among sponsors, sites, and teams.

What is a senior clinical research associate (CRA)?

Senior Clinical Research Associates (Senior CRAs) are experienced professionals responsible for overseeing and monitoring clinical trials to ensure compliance with regulatory guidelines, protocols, and good clinical practice. They play a key role in managing study sites, reviewing data, and ensuring the integrity and quality of clinical research. Senior CRAs also mentor junior staff, resolve complex issues, and maintain effective communication between sponsors, sites, and regulatory bodies. Their expertise helps ensure that clinical trials are conducted safely and efficiently.

What does a senior clinical research associate do?

A senior clinical research associate (CRA) oversees and monitors clinical trials to ensure compliance with protocols, Good Clinical Practice (GCP), and regulatory requirements. They coordinate with study sites, review data quality, and may mentor junior staff, often using electronic data capture systems and requiring relevant certifications like a CRA certification. Their role is essential in ensuring the integrity and accuracy of clinical trial data.
What are the most commonly searched types of Cra jobs in Raleigh, NC? The most popular types of Cra jobs in Raleigh, NC are:
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Senior Cra jobs near you
Infographic showing various Senior Cra job openings in Raleigh, NC as of August 2026, with employment types broken down into 100% Full Time. Highlights an 55% In-person, 9% Hybrid, and 36% Remote job distribution, with an average salary of $91,681 per year, or $44.1 per hour.

Sr. Clinical Operations Lead (Clinical Trial Manager)

Alimentiv

Raleigh, NC • On-site

Full-time

Re-posted 21 days ago

Job description

Responsible for the clinical operations of a project within a defined regional/global level.  Provides oversight of project deliverables, assigned Clinical Research Associate (CRAs) and Investigator sites in accordance with the Monitoring Plan, Protocol, Good Clinical Practice (GCP), ICH guidelines and local regulations.  The COL acts as a primary liaison between the CRAs and the clinical project team.  Additional responsibilities include project specific training of CRAs, conducting assessment visits with CRAs, implementation of enrollment and recruitment strategies, preparation of the monitoring plan and other structural documentation and the oversight of monitoring visit scheduling, site and monitoring performance metrics, issue escalation and corrective actions.  The COL will develop study tools for site and CRA use, review visit reports, review and track protocol deviations, and support other objectives for clinical operations and the clinical project team.
Project Oversight
  • Overall oversight of (a group of) regional CRAs to ensure (site) compliance with study protocol, study plans, ICH-GCP, local regulations and study timelines.
  • Monitoring support visits (Co-monitoring), per project requirements, to aid the site/CRA in the satisfactory performance and compliance with standards mentioned above.
  • May support clinical project team by providing oversight of study deliverables related to other departments (e.g. Data Management, TMF Operations, etc.)
  • Oversee regional startup and feasibility activities.
  • Assist in vendor management activities as required per project.
  • Perform review of visit reports for quality, compliance and appropriate site management.
  • Assure compliance with high quality and timely project deliverables according to the project requirements and the monitoring plan.
  • Proactive management of site and country performance (recruitment, data collection, document collection, TMF review etc.) and inform clinical project team on progress.
  • Contribute to financial project management processes as applicable.  May include but may not be limited to input on revenue recognition, site payments, and site pass-through expense review.
  • May be required to manage/oversee investigator sites including CRA responsibilities, on a temporary or permanent basis.         
Project Liaison
  • Conduct regular global CRA calls with the monitoring and site management team, as well as individual/country CRA calls 
  • Attend meetings with Study Sponsor to provide status updates on country and site progress
  • Provide operational support and guidance to the monitoring team throughout project.
  • Provide project training/mentoring to regional CRAs on study procedures, clinical plans and guidelines, and timelines for the study. Ensures study specific training requirements are completed and documented.
  • First point of contact for regional CRAs for study-specific questions and issues. Escalates to PM and other functions as appropriate.
  • Support line managers by providing status updates on utilization and performance of CRAs. 
  • Liaise with line manager for assigning sites to CRAs following line manager allocation of a CRA resource to the project. 
  • Conduct CRA Assessment visits per departmental requirements to assess the performance of the CRA against their monitoring responsibilities.
Study Documents and Plans
  • Develop training materials and study tools for sites and CRAs, including monitoring plans.
  • Develop and implement enrolment and recruitment strategies together with clinical project team.
  • Develop presentation materials for and presents at Sponsor Kickoff meetings, Investigator meetings and Sponsor Calls (as needed), and prepares presentations for Site Qualification Visits and Site Initiation Visits.
 
Qualifications
  • College diploma/degree AND 7-9 years related experience +continuous training and knowledge/skills upgrading
OR
  • Undergraduate university degree (Bachelors or Honors Bachelors) AND 4-6 years' experience + substantial on-going job-related training
Other
  • Health Sciences, Life Sciences or Nursing specialty preferred, or SoCRA and/or ACRP Certification/Designation.
  • Should have a minimum of 3 years CRA experience, have strong experience with EDC systems, be proficient with MS Office, have strong written and verbal communication skills and highly effective interpersonal and organizational skills.
  • Demonstrate the following attributes: proactive, detail oriented, task-driven and highly organized.
  • Demonstrate the critical elements of GCPs and local regulations as they relate to clinical monitoring, IRB/EC and Investigator responsibilities.
  • Demonstrated ability in report writing and strong ability to critically understand clinical research documents.
  • Ability to handle multiple tasks to meet deadlines in a dynamic environment. 
 
Working Conditions
  • Home-based
$86,000 - $143,000 a year
+ Bonus
Accommodations for persons with disabilities are available on request in respect of all aspects of the recruitment and selection lifecycle. Requests can be directed to [email protected]
 
PHISHING SCAM WARNING: Alimentiv is aware of the continued increase of phishing scams, leveraging various methods of attack via email, text, voice and social media. Please note that Alimentiv only uses company email addresses, which contain "@alimentiv.com", to communicate with candidates via email. If you are contacted by someone about an open job at Alimentiv, please verify the domain of the sender's email address and that they are asking you to apply on this website. If you believe you've been a victim of a phishing scam, please contact your local government cyber authority to report.
 
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