Clinical Research Monitor Jobs in Raleigh, NC (NOW HIRING)

School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.

Be You. Be Bold. Choose Duke.

Clinical Research Coordinator - Neurosurgery Research

Be You.

At Duke, we celebrate individuality and the unique perspectives each team member brings to advancing medicine and improving lives. As a Clinical Research Coordinatorwithin the Department of Neurosurgery, you will join a highly collaborative team dedicated to groundbreaking clinical research in both adult and pediatric populations. Our studies span Parkinson's disease, Alzheimer's disease, epilepsy, neuro-oncology, rare genetic disorders, traumatic brain and spinal injuries, chronic pain, and other complex neurological conditions.

You'll work alongside nationally recognized neurosurgeons, neuro-oncologists, scientist-clinicians, and PhD researchers who are passionate about discovery, innovation, and transforming patient care. If you thrive in a dynamic academic research environment and enjoy solving complex challenges while making a meaningful impact, Duke Neurosurgery offers an exceptional opportunity to grow your career.

Be Bold.

What You'll Do

As a senior clinical research professional, you will lead and support complex clinical trials throughout the study lifecycle while serving as a trusted resource for research teams, sponsors, and investigators.

Clinical Trial Operations

• Coordinate and manage complex clinical research studies, including drug, device, and procedural trials involving randomization, blinding, crossover designs, and investigational products.
• Maintain study documentation and regulatory records to ensure continuous compliance with institutional, sponsor, FDA, and international requirements.
• Prepare and support FDA submissions in partnership with regulatory experts and investigators.
• Manage investigational products, including receipt, storage, accountability, tracking, and participant dispensing.
• Serve as a primary liaison with sponsors, Contract Research Organizations (CROs), Investigational Drug Services (IDS), and internal stakeholders.
• Lead study monitoring, audit preparation, and corrective action activities.
• Support study startup, feasibility assessments, ongoing project management, and study closeout activities.

Participant Recruitment & Retention

• Develop and implement recruitment and retention strategies for complex clinical research studies.
• Screen, enroll, and monitor research participants while ensuring protocol adherence and participant safety.
• Identify barriers to enrollment and retention and implement solutions that enhance study performance.
• Conduct study visits in accordance with approved protocols and regulatory requirements.
• Participate in an established on-call research coverage rotation supporting critical care research activities.

Regulatory & Ethical Compliance

• Lead IRB submissions, amendments, continuing reviews, and safety reporting activities.
• Conduct informed consent discussions for studies involving greater-than-minimal risk and complex interventions.
• Collaborate with investigators to assess adverse events, determine reportability requirements, and maintain participant safety oversight.
• Develop and maintain regulatory tools, templates, standard operating procedures, and compliance resources.

Data & Research Excellence

• Ensure the integrity, quality, security, and completeness of research data.
• Utilize clinical research systems and electronic data capture tools to support protocol execution and reporting.
• Apply FAIR data principles and open science practices to facilitate data sharing and reproducibility.
• Support data management activities, including data cleaning, validation, quality assurance, database testing, and reporting.
• Create study progress reports, visualizations, summaries, and presentations for investigators and stakeholders.
• Assist with qualitative and quantitative data analyses using software such as SAS, R, SPSS, NVivo, or Atlas.ti.

Scientific Contribution

• Participate in protocol development, scientific literature reviews, and grant proposal preparation.
• Contribute to abstracts, presentations, posters, and peer-reviewed publications.
• Serve as an author or co-author on research dissemination activities when appropriate.

Leadership & Collaboration

• Mentor, train, and support research staff and study teams.
• Lead or contribute to multidisciplinary meetings involving investigators, sponsors, research partners, and institutional stakeholders.
• Share best practices and help develop operational resources that improve research performance.
• Serve on committees, workgroups, and professional development initiatives that advance Duke's research mission.
• Continuously expand expertise through professional development, certifications, and participation in research-focused educational opportunities.

What You'll Bring

Required Qualifications

• Bachelor's degree in a health-related, scientific, or research discipline, or an equivalent combination of education and experience.
• Experience coordinating clinical research studies with progressive responsibility.
• Demonstrated knowledge of clinical research regulations, Good Clinical Practice (GCP), FDA requirements, and human subject protections.
• Experience managing multiple priorities in a fast-paced research environment.
• Strong organizational, communication, problem-solving, and project management skills.

Preferred Qualifications

• Experience supporting neurology, neurosurgery, neuro-oncology, critical care, or device-based clinical research.
• Experience with investigational product management and complex interventional clinical trials.
• Knowledge of OnCore, eReg, Maestro Care/Epic, REDCap, or other clinical research systems.
• Professional certification such as CCRP, CCRC, ACRP, or SOCRA certification.
• Experience contributing to publications, grant submissions, or scientific presentations.

Key Competencies

• Clinical trial management
• Regulatory compliance
• Participant engagement and retention
• Data quality and data management
• Cross-functional collaboration
• Critical thinking and problem solving
• Scientific communication
• Leadership and mentorship
• Adaptability and resilience
• Continuous improvement mindset

Choose Duke.

At Duke, you'll find more than a job. You'll find a community committed to innovation, excellence, and improving human health.

Why Duke?

• Work alongside world-renowned clinicians, researchers, and educators.
• Contribute to pioneering neuroscience and neurosurgical discoveries.
• Join a collaborative team culture built on respect, inclusion, and shared success.
• Access extensive professional development, training, and career advancement opportunities.
• Support research that directly impacts patients and families around the world.

A Culture of Belonging

Duke is committed to fostering an environment where every individual feels valued, respected, and empowered to contribute. We believe diverse backgrounds, experiences, and perspectives fuel innovation and strengthen our ability to improve lives through research, education, and patient care.

Ready to Make a Difference?

Apply now and help advance life-changing neuroscience research while building a meaningful career with Duke University School of Medicine.