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Clinical Research Monitor Jobs in Raleigh, NC (NOW HIRING)

Duke University

Clinical Research Coordinator

Durham, NC · On-site

$23.50 - $31.25/hr

May train others. Prepares for and provides support for study monitoring and audit visits ... Uses clinical research management system and its reports to manage research participants ...

Duke University

Clinical Research Coordinator

Durham, NC · On-site

$23.50 - $31.25/hr

May train others. Prepares for and provides support for study monitoring and audit visits ... Uses clinical research management system and its reports to manage research participants ...

IQVIA

Sr. Clinical Research Associate, IQVIA

Durham, NC · On-site

$87K - $169K/yr

IQVIA is hiring Senior Clinical Research Associate 1 with experience in either oncology ... Perform monitoring and site management work to ensure that sites are conducting the study(ies) and ...

IQVIA

Sr. Clinical Research Associate, IQVIA

Durham, NC · On-site

$87K - $169K/yr

IQVIA is hiring Senior Clinical Research Associate 1 with experience in either oncology ... Perform monitoring and site management work to ensure that sites are conducting the study(ies) and ...

IQVIA

Clinical Research Associate 2, IQVIA

Durham, NC

$71K - $189K/yr

IQVIA is hiring a Clinical Research Associate 2 with on-site monitoring experience in IM/GI, MASH ... Job Overview Perform monitoring and site management work to ensure that sites are conducting the ...

IQVIA, Inc.

Clinical Research Associate 2, IQVIA

Durham, NC · On-site

$71K - $189K/yr

IQVIA is hiring a Clinical Research Associate 2 with on-site monitoring experience in IM/GI, MASH ... Job Overview Perform monitoring and site management work to ensure that sites are conducting the ...

IQVIA

Clinical Research Associate 2, IQVIA

Durham, NC · On-site

$71K - $189K/yr

IQVIA is hiring a Clinical Research Associate 2 with on-site monitoring experience in IM/GI, MASH ... Job Overview Perform monitoring and site management work to ensure that sites are conducting the ...

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Clinical Research Monitor information

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How much do clinical research monitor jobs pay per hour?

As of Aug 20, 2026, the average hourly pay for clinical research monitor in Raleigh, NC is $37.62, according to ZipRecruiter salary data. Most workers in this role earn between $37.16 and $38.08 per hour, depending on experience, location, and employer.

What is a clinical research monitor?

A clinical research monitor, also called a clinical research associate, oversees the operations of a clinical trial to ensure that it meets all safety and governmental regulations. As a clinical research monitor, your job duties include traveling to testing sites, inspecting the procedures, documenting results from the trial, and verifying that all collected data is accurate and verified. Your primary responsibility is to make sure the testing is conducted safely and within industry and governmental guidelines.

What are the key skills and qualifications needed to thrive as a clinical research monitor?

To thrive as a Clinical Research Monitor, you need a solid understanding of clinical trial protocols, regulatory compliance (such as GCP), and a degree in life sciences or a related field. Familiarity with electronic data capture systems, trial management software, and certifications like ACRP or SOCRA are highly valued. Excellent organizational skills, attention to detail, and effective communication are essential soft skills for managing site relationships and ensuring protocol adherence. These competencies are crucial for safeguarding data integrity, patient safety, and regulatory compliance throughout the clinical trial process.

What are some common challenges clinical research monitors face when overseeing multiple study sites?

Clinical Research Monitors often encounter challenges such as managing varying levels of compliance across different sites, coordinating communication between site staff and sponsors, and ensuring timely data collection and reporting. Travel between sites and adapting to diverse protocols or site-specific processes can also present logistical hurdles. Successful monitors develop strong organizational skills, maintain meticulous documentation, and build collaborative relationships with site teams to navigate these challenges effectively.

What is the difference between Clinical Research Monitor vs Clinical Research Associate?

AspectClinical Research MonitorClinical Research Associate
CertificationsOften required or preferred certifications like CCRP or CCRASimilar certifications such as CCRP or CCRA are common
Work EnvironmentMonitoring visits at sites, reviewing data, ensuring complianceSite visits, data collection, and regulatory documentation
Employer & Industry UsagePharmaceutical companies, CROs, biotech firmsPharmaceutical companies, CROs, biotech firms

Both roles involve overseeing clinical trial activities, ensuring compliance, and maintaining data integrity. While the titles are often used interchangeably, the term 'Clinical Research Monitor' emphasizes the monitoring aspect, whereas 'Clinical Research Associate' may encompass broader responsibilities in clinical trial management. Both roles require similar certifications and work in comparable environments within the industry.

What does a clinical research monitor do in clinical research?

A clinical research monitor oversees the progress of clinical trials to ensure compliance with protocols, Good Clinical Practice (GCP), and regulatory requirements. They conduct site visits, review data for accuracy, and verify that trial procedures are followed correctly, often using electronic data capture systems. Monitoring is essential for maintaining data integrity and participant safety throughout the study.
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Clinical Research Monitor jobs near you
Infographic showing various Clinical Research Monitor job openings in Raleigh, NC as of August 2026, with employment types broken down into 3% As Needed, 72% Full Time, 17% Part Time, and 8% Contract. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution, with an average salary of $78,252 per year, or $37.6 per hour.

Senior Clinical Research Associate - US

Optimapharm d.o.o.

Durham, NC • On-site, Remote

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 12 days ago

Job description

Location: Remote
Who we are?
Optimapharm is a mid-sized, global Contract Research Organisation (CRO) turning science into hope through agile, patient-focused clinical development. We specialise in Phase I-IV clinical studies, delivering Full-Service and Functional Service Provision (FSP) solutions that help sponsors move faster and execute with confidence.
With operations in 40+ countries and 2x the patient reach of the average mid-sized CRO, we enable accelerated regulatory pathways, faster study start-up, and access to diverse patient populations worldwide. At Optimapharm, you'll contribute to meaningful clinical research while growing your career in a dynamic, people‑focused, global environment.
As our US Clinical Operations team continues to grow, we're looking for a Senior CRA who is committed to clinical excellence, passionate about mentoring others, and driven by the opportunity to help bring innovative treatments to patients faster.
At Optimapharm, you'll work on diverse and challenging studies, collaborate with experienced professionals around the world, and play a critical role in shaping the success of clinical trials - all within a culture that supports continuous growth and recognizes expertise.
What do we offer?
  • Working in a successful company that's growing and developing every day
  • Being part of a clinical research team that transforms science into hope for patients
  • International projects and professional growth
  • Company that supports life balance
  • Company with healthy culture
  • Working with a highly experienced team of clinical research professionals
  • Competitive salary
  • Competitive PTO entitlement
  • Health insurance, including vision and dental plans, to meet your and your family's needs
  • Comprehensive pension plan to maximize savings and prepare confidently for the future
  • Employee engagement programs
  • Well-being initiatives
  • Training and development program
  • Fast-paced career path progression

Who are we looking for?
Qualifications and Experience
  • University degree, preferably in medical or life sciences; nursing education or other relevant healthcare college degree
  • At least 3-5 years of independent clinical trial monitoring experience in oncology
  • High level of knowledge of ICH GCP Guidelines, knowledge of regulatory requirements and a strong interest in clinical research
  • Computer proficiency is mandatory
  • Ability to read, analyze, and interpret common scientific and technical journals
  • Excellent verbal and written communication skills
  • Very good interpersonal and negotiation skills
  • Ability to work independently, pro-active
  • Affinity to work effectively and efficiently in a matrix environment
  • A current, valid driver's license

Your responsibilities
  • Perform routine site visits independently, including pre-study, initiation, interim monitoring and closeout visits
  • Manage assigned sites by regular contact with site personnel to ensure site compliance, adequate enrolment and understanding of study requirements
  • Independently perform CRF review; query generation and resolution against established data review guidelines or data management systems as applicable
  • Identifying and escalating potential risks and identifying retraining opportunities for site personnel
  • Preparation of corrective and preventive (CAPA) plans for issues identified during monitoring activities and pro-active follow of each, individual CAPA until timely resolution
  • Preparation of documents required for EC submissions and notifications, translation of study-related documents (where applicable), and other tasks as instructed by the supervisor
  • Independently negotiate study budgets with potential investigators/institutions and assist with the execution of site contracts as applicable
  • Administration of site payments in accordance with relevant project instructions

By joining our fast-growing and prosperous team, you will have an excellent opportunity for further personal growth and career development.
If you would be interested in joining the Optimapharm team, please send your CV and note that only shortlisted candidates who meet the requirements will be contacted for the further selection process.
Compensation is competitive and final offers will reflect each candidate's experience, skills, and qualifications.
Disclaimer: Unsolicited CVs sent to Optimapharm (Talent Acquisition Team, Hiring Managers or any other OPT employee) by recruitment agencies will not be considered for this role. Optimapharm follows a direct sourcing strategy and collaborates exclusively with selected recruitment partners when external support is required.

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