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Senior Bioinformatics Software Engineer Jobs (NOW HIRING)

Natera

Senior Bioinformatics Scientist

San Carlos, CA · On-site

They are seeking a Senior Bioinformatics Scientist to lead the architecture, development, and ... • Strong software engineering proficiency in Java or C++ within a professional production ...

Natera

Senior Bioinformatics Scientist

San Carlos, CA · On-site

This role is responsible for building production-grade software tools to analyze next-generation ... Engineer novel genomic analysis tools and proactively identify optimization pathways to enhance ...

Natera

OR · On-site

This role is responsible for building production-grade software tools to analyze next-generation ... Engineer novel genomic analysis tools and proactively identify optimization pathways to enhance ...

Natera

Senior Bioinformatics Scientist

San Jose, CA

$130K - $163K/yr

Natera is seeking a Senior Bioinformatics Scientist to lead the architecture, development, and ... business professionals, software engineers and many other professionals from world-class ...

Natera

Senior Bioinformatics Scientist

San Carlos, CA · On-site

$130K - $163K/yr

Natera is seeking a Senior Bioinformatics Scientist to lead the architecture, development, and ... business professionals, software engineers and many other professionals from world-class ...

Natera

Senior Bioinformatics Scientist

$117K - $146K/yr

Natera is seeking a Senior Bioinformatics Scientist to lead the architecture, development, and ... business professionals, software engineers and many other professionals from world-class ...

Natera

Senior Bioinformatics Scientist

San Francisco, CA · On-site +1

$117K - $146K/yr

Natera is seeking a Senior Bioinformatics Scientist to lead the architecture, development, and ... business professionals, software engineers and many other professionals from world-class ...

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All JobsSenior Bioinformatics Software Engineer Jobs

Senior Bioinformatics Software Engineer information

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$84.5K

$102.3K

$119.5K

How much do senior bioinformatics software engineer jobs pay per year?

As of Jun 27, 2026, the average yearly pay for senior bioinformatics software engineer in the United States is $102,271.00, according to ZipRecruiter salary data. Most workers in this role earn between $94,500.00 and $110,000.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Senior Bioinformatics Software Engineer, and why are they important?

To thrive as a Senior Bioinformatics Software Engineer, you need a strong background in computer science, biology, and data analysis, often supported by an advanced degree in bioinformatics or a related field. Expertise with programming languages (such as Python, R, or Java), cloud computing, bioinformatics tools, and version control systems is typically required, along with experience using databases and relevant software frameworks. Strong problem-solving skills, collaboration, and effective communication are crucial soft skills for working with multidisciplinary teams and presenting complex data. These combined skills enable the effective development and maintenance of robust software tools that support cutting-edge biological research and data-driven discoveries.

How does a Senior Bioinformatics Software Engineer typically collaborate with cross-functional teams in a research or clinical setting?

Senior Bioinformatics Software Engineers frequently work alongside biologists, data scientists, and clinicians to develop and maintain computational pipelines for data analysis. They play a key role in translating complex biological questions into scalable software solutions, often leading code reviews, mentoring junior developers, and ensuring data integrity. Regular meetings and clear communication are vital, as the role requires aligning technical development with scientific goals and regulatory requirements. This collaborative environment offers opportunities to influence project direction and contribute to impactful discoveries.

What does a Senior Bioinformatics Software Engineer do?

A Senior Bioinformatics Software Engineer designs, develops, and maintains software tools and pipelines to analyze biological data, such as genomic or proteomic information. They work closely with scientists and researchers to understand data requirements and translate them into efficient, scalable computational solutions. Their responsibilities often include coding, troubleshooting, optimizing algorithms, as well as mentoring junior engineers and contributing to project planning. Senior engineers are expected to have strong programming skills, a solid understanding of bioinformatics concepts, and experience working with large biological datasets.

What is the difference between Senior Bioinformatics Software Engineer vs Bioinformatics Software Engineer?

AspectSenior Bioinformatics Software EngineerBioinformatics Software Engineer
Required CredentialsBachelor's or Master's in Bioinformatics, Computer Science, or related field; experience in software development and bioinformatics toolsBachelor's or Master's in Bioinformatics, Computer Science, or related field; less emphasis on extensive experience
Work EnvironmentResearch labs, biotech companies, healthcare institutions, often leading projectsResearch teams, biotech firms, academic settings, supporting bioinformatics analysis
Employer & Industry UsageUsed in biotech, pharma, healthcare, research institutionsCommon in similar industries, often as entry to mid-level roles

The main difference between a Senior Bioinformatics Software Engineer and a Bioinformatics Software Engineer lies in experience and responsibility. Senior roles typically require more advanced skills, leadership, and project management, while entry-level roles focus on supporting bioinformatics analysis and software development. Both roles are vital in biotech and research industries, but senior positions involve greater oversight and strategic input.

More about Senior Bioinformatics Software Engineer jobs
What cities are hiring for Senior Bioinformatics Software Engineer jobs? Cities with the most Senior Bioinformatics Software Engineer job openings:
What are the most commonly searched types of Bioinformatics Software Engineer jobs? The most popular types of Bioinformatics Software Engineer jobs are:
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What job categories do people searching Senior Bioinformatics Software Engineer jobs look for? The top searched job categories for Senior Bioinformatics Software Engineer jobs are:
Senior Bioinformatics Software Engineer jobs near you
Infographic showing various Senior Bioinformatics Software Engineer job openings in the United States as of June 2026, with employment types broken down into 1% As Needed, 80% Full Time, 16% Part Time, and 3% Contract. Highlights an 89% Physical, 4% Hybrid, and 7% Remote job distribution, with an average salary of $102,271 per year, or $49.2 per hour.
Senior Bioinformatics Research

Senior Bioinformatics Research

Harvard University

Cambridge, MA • On-site

Full-time

Posted 16 days ago

Harvard University rating

8.1

Company rating: 8.1 out of 10

Based on 7 frontline employees who took The Breakroom Quiz

133rd of 541 rated colleges and universities

Job description

Position
Details
Title
Senior Bioinformatics Research
School
Harvard Medical School
Department/Area
Perrimon Lab
Position Description
We are seeking a highly motivated post-doc trainee to join Dr. Norbert Perrimon's group in the Program of Genetics at Harvard Medical School. Perrimon lab is actively generating data sets of omics scale and this position will involve working with other post-doc trainees in the lab who are responsible of design and generating such datasets. In addition, this position involves working with DRSC/TRiP functional genomics core, a multi-disciplinary team of biologists, software engineers and bioinformaticians as we develop and leverage technological breakthroughs to explore the biology of complex systems. Principal Responsibilities include 1.) Design and implement reusable bioinformatics analysis pipelines for processing RNA-seq, single-cell RNA-seq, genomics and proteomics data. Develop novel algorithms and integrated data visualization applications when existing software packages are not available or are not adequate. 2.) Apply computational, statistical, and AI/ML approaches to uncover biological insights and support functional discovery by analyzing multi-omics datasets eg. genomics, transcriptomics, proteomics, metabolomics, and related datasets. 3.) Help develop custom databases, web portals and pipelines for managing raw and processed experimental data as well as reagent identification/designs. 4.) Collaborate closely with Investigator and lab members on research projects including defining the scope of the collaboration, researching the scientific topics and implementing the appropriate bioinformatics solutions that meet project timelines. Coordinate and collaborate with other bioinformaticians, biostatisticians, information technology professionals, and interdepartmental project teams. 5.) Properly document the procedures used in computational analysis, provide the summary reports of results, and contribute to grant and manuscript writing.
Salary and Benefits
This position is salaried and benefits eligible. Information regarding postdoctoral fellow salary, which is determined by the number of years post PhD, and benefits can be found at https://postdoc.hms.harvard.edu/guidelines.
With this appointment, you are represented by the Harvard Academic Workers (HAW) - UAW for purposes of collective bargaining and matters affecting your compensation and working conditions.
Basic Qualifications
Doctoral degree in Bioinformatics or in biology with extensive experience analyzing omics data. Strong background in programming, algorithms and statistics. Familiarity with programming techniques for analyzing data sets and experience working with BIG DATA (eg. NGS data in multi-TB scale). Experience using genome alignment software (bowtie2, bwa, tophat, etc.) is desired. Fluent in one programming language (Python, C, C++ or Java) and familiarity with scripting languages (bash, Perl). Knowledge of Unix operating system, terminal and bash is a plus. Experience using a compute cluster. Excellent information management skills.
Additional Qualifications
Experience using relational databases, SQL and / or structured data formats. Web programming experience (PHP, Django, JavaScript, JQuery, JSON, REST API) is a plus. Excellent oral and written communication skills as well as the ability to collaborate effectively with a diverse team.
Special Instructions
Contact Information
Claire Yanhui Hu
Contact Email
claire_hu@genetics.med.harvard.edu
Salary Range
Information regarding postdoctoral fellow salary, which is determined by the number of years post PhD, can be found at https://postdoc.hms.harvard.edu/guidelines.
Minimum Number of References Required
3
Maximum Number of References Allowed
3
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