1

Senior Bioinformatics Software Engineer Jobs (NOW HIRING)

Natera is seeking a Senior Bioinformatics Scientist to join our Bioinformatics team dedicated to ... business professionals, software engineers and many other professionals from world-class ...

Natera is seeking a Senior Bioinformatics Scientist to join our Bioinformatics team dedicated to ... PhD in Bioinformatics, Computer Science, Engineering, Statistics, Cancer Biology or similar field ...

Natera is seeking a Senior Bioinformatics Scientist to join our Bioinformatics team dedicated to ... business professionals, software engineers and many other professionals from world-class ...

Showing results 21-40

Senior Bioinformatics Software Engineer information

See salary details

$84.5K

$102.3K

$119.5K

How much do senior bioinformatics software engineer jobs pay per year?

As of Aug 7, 2026, the average yearly pay for senior bioinformatics software engineer in the United States is $102,271.00, according to ZipRecruiter salary data. Most workers in this role earn between $94,500.00 and $110,000.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a senior bioinformatics software engineer?

To thrive as a Senior Bioinformatics Software Engineer, you need a strong background in computer science, biology, and data analysis, often supported by an advanced degree in bioinformatics or a related field. Expertise with programming languages (such as Python, R, or Java), cloud computing, bioinformatics tools, and version control systems is typically required, along with experience using databases and relevant software frameworks. Strong problem-solving skills, collaboration, and effective communication are crucial soft skills for working with multidisciplinary teams and presenting complex data. These combined skills enable the effective development and maintenance of robust software tools that support cutting-edge biological research and data-driven discoveries.

How does a senior bioinformatics software engineer typically collaborate with cross-functional teams in a research or clinical setting?

Senior Bioinformatics Software Engineers frequently work alongside biologists, data scientists, and clinicians to develop and maintain computational pipelines for data analysis. They play a key role in translating complex biological questions into scalable software solutions, often leading code reviews, mentoring junior developers, and ensuring data integrity. Regular meetings and clear communication are vital, as the role requires aligning technical development with scientific goals and regulatory requirements. This collaborative environment offers opportunities to influence project direction and contribute to impactful discoveries.

What does a senior bioinformatics software engineer do?

A Senior Bioinformatics Software Engineer designs, develops, and maintains software tools and pipelines to analyze biological data, such as genomic or proteomic information. They work closely with scientists and researchers to understand data requirements and translate them into efficient, scalable computational solutions. Their responsibilities often include coding, troubleshooting, optimizing algorithms, as well as mentoring junior engineers and contributing to project planning. Senior engineers are expected to have strong programming skills, a solid understanding of bioinformatics concepts, and experience working with large biological datasets.

What is the difference between Senior Bioinformatics Software Engineer vs Bioinformatics Software Engineer?

AspectSenior Bioinformatics Software EngineerBioinformatics Software Engineer
Required CredentialsBachelor's or Master's in Bioinformatics, Computer Science, or related field; experience in software development and bioinformatics toolsBachelor's or Master's in Bioinformatics, Computer Science, or related field; less emphasis on extensive experience
Work EnvironmentResearch labs, biotech companies, healthcare institutions, often leading projectsResearch teams, biotech firms, academic settings, supporting bioinformatics analysis
Employer & Industry UsageUsed in biotech, pharma, healthcare, research institutionsCommon in similar industries, often as entry to mid-level roles

The main difference between a Senior Bioinformatics Software Engineer and a Bioinformatics Software Engineer lies in experience and responsibility. Senior roles typically require more advanced skills, leadership, and project management, while entry-level roles focus on supporting bioinformatics analysis and software development. Both roles are vital in biotech and research industries, but senior positions involve greater oversight and strategic input.

More about Senior Bioinformatics Software Engineer jobs
What cities are hiring for Senior Bioinformatics Software Engineer jobs? Cities with the most Senior Bioinformatics Software Engineer job openings:
What are the most commonly searched types of Bioinformatics Software Engineer jobs? The most popular types of Bioinformatics Software Engineer jobs are:
What states have the most Senior Bioinformatics Software Engineer jobs? States with the most job openings for Senior Bioinformatics Software Engineer jobs include:
What job categories do people searching Senior Bioinformatics Software Engineer jobs look for? The top searched job categories for Senior Bioinformatics Software Engineer jobs are:
Infographic showing various Senior Bioinformatics Software Engineer job openings in the United States as of August 2026, with employment types broken down into 88% Full Time, 8% Part Time, and 4% Contract. Highlights an 88% Physical, 3% Hybrid, and 9% Remote job distribution, with an average salary of $102,271 per year, or $49.2 per hour.

Senior Bioinformatics Engineer II

Moderna, Inc.

Cambridge, MA • On-site

Full-time

PTO

Re-posted 8 days ago


Moderna rating

9.2

Company rating: 9.2 out of 10

Based on 10 frontline employees who took The Breakroom Quiz

5th of 86 rated pharmaceutical


Job description

The Role
Joining Moderna means advancing mRNA science to transform medicine. Work with exceptional global teams on a broad pipeline and build a career that makes a real difference for patients.
Moderna is strengthening its international business services hub in Warsaw, supporting our growing global operations. We welcome professionals ready to help advance our mission and shape the future of mRNA medicines.
In this role, you will help ensure the reliability, quality, and compliance of critical bioinformatics pipelines that support Moderna's scientific and operational objectives. Working at the intersection of bioinformatics, software engineering, validation, and operational support, you will monitor system performance, identify deviations from established standards, and drive continuous improvements across the software ecosystem.
You will play a key role in maintaining continuous software operations, supporting validation activities, enhancing automation capabilities, and collaborating with multidisciplinary teams to strengthen the robustness of scientific software platforms. This position also offers exposure to advanced digital technologies and opportunities to work alongside teams leveraging automation, data-driven processes, and emerging Generative AI-enabled solutions to improve operational efficiency.
Here's What You'll Do
  • Monitor bioinformatics pipelines and scientific software systems to identify deviations from established standards and recommend corrective actions.
  • Support the development, refinement, and implementation of standards, methods, and procedures used to assess software quality and operational readiness.
  • Collaborate closely with bioinformatics and software engineering teams to design, develop, and enhance automated testing capabilities that support continuous operation of bioinformatics pipelines.
  • Monitor and maintain scientific software platforms to ensure reliable and uninterrupted performance.
  • Troubleshoot, investigate, resolve, or appropriately annotate software and operational issues to support efficient incident management.
  • Support computer system validation activities through the drafting, execution, and maintenance of qualification scripts, protocols, and associated validation documentation.
  • Work independently and in partnership with development teams to identify software defects, resolve bugs, and implement system improvements.
  • Provide on-call support to address urgent operational issues and minimize downtime.
  • Develop, maintain, and continuously improve documentation related to software troubleshooting, issue investigation, issue resolution, and operational procedures.
  • Improve and automate error reporting applications to increase visibility, efficiency, and system reliability.
  • Continuously expand technical knowledge of scientific software platforms, bioinformatics technologies, and supporting infrastructure.
  • Contribute to a culture of operational excellence, continuous improvement, compliance, and high-quality software delivery.

The key Moderna Mindsets you'll need to succeed in the role:
  • "We obsess over learning. We don't have to be the smartest we have to learn the fastest."
  • "We digitize everywhere possible using the power of code to maximize our impact on patients."

Here's What You'll Need (Minimum Qualifications)
  • Bachelor's degree in Computer Science, Engineering, or a related field and 10+ years of relevant work experience
  • Strong programming skills, particularly in Python and Linux
  • Excellent problem-solving and analytical skills
  • Ability to work independently and as part of a team
  • Experience using a bioinformatics workflow framework (e.g. NextFlow, Luigi, Snakemake, NextFlow preferred), version control systems (Git preferred), Cloud (AWS preferred) and containers (Docker preferred)
  • Experience with Computer System Validation processes.
  • Experience in a GxP environments and knowledge of regulatory compliance requirements

Here's What You'll Bring to the Table (Preferred Qualifications)
  • Experience with bioinformatics software and an understanding of neoantigen therapies
  • Proven experience in software quality assurance and quality control
  • Effective time management, organization, and planning skills
  • Flexibility; adaptability to frequent change
  • Results oriented; ability to manage performance.
  • Effective communication, both written and verbal
  • Personal and shared accountability
  • A desire to make an impact as part of a high-growth, transformational company that is Bold, Relentless, Curious, and Collaborative.

Pay & Benefits
At Moderna, we believe that when you feel your best, you can do your best work. That's why our benefits and well-being resources are designed to support you-at work, at home, and everywhere in between.
  • Competitive healthcare, plus voluntary benefit programs to support your unique needs
  • A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
  • Family planning benefits, including fertility, adoption, and surrogacy support
  • Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
  • Savings and investments to help you plan for the future
  • Location-specific perks and extras

The salary range for this role is $145,900.00 - $234,200.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual's position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs.The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance.
About Moderna
Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.
By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.
We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.
If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.
Our Working Model
As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact.
Moderna is a smoke-free, alcohol-free, and drug-free work environment.
Equal Opportunities
Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!
Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.
Accommodations
We're focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best.
Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at leavesandaccommodations@modernatx.com.
Export Control NoticeThis position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant's ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role Moderna is unable to sponsor non-U.S. persons to apply for an export control license.#LI-CK1

What Moderna employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom


Moderna logo

About Moderna

Sourced by ZipRecruiter

In just over a decade, Moderna has evolved from a research-focused company in the messenger RNA (mRNA) field to a leading enterprise with a diverse clinical portfolio of vaccines and therapeutics. With a strong intellectual property portfolio and state-of-the-art manufacturing capabilities, Moderna collaborates with global partners to advance groundbreaking science and achieve rapid scaling of production. Notably, Moderna's mRNA platform has enabled the development of therapies for various diseases, including infectious diseases, immuno-oncology, and cardiovascular conditions. Recognized as a top biopharmaceutical employer, Moderna fosters an inclusive and smoke-free work environment. The company is dedicated to equal employment opportunities and non-discrimination, ensuring that all employees and applicants are treated with respect and without bias based on factors like race, gender, religion, disability, or sexual orientation. Moderna is also committed to providing reasonable accommodations for individuals with disabilities, in accordance with applicable laws. To know more, visit www.modernatx.com.

Industry

Manufacturing

Company size

501 - 1,000 Employees

Headquarters location

Cambridge, MA, US

Year founded

2010

Social media