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Senior Bioinformatics Software Engineer Jobs in Wisconsin

micro1 AI

Bioinformatics Software Engineer

Green Bay, WI · Remote

$80 - $110/hr

Analyze and interpret small-molecule and drug discovery datasets using advanced computational biology, bioinformatics, and cheminformatics methods. * Curate, annotate, and validate chemical and ...

micro1 AI

Bioinformatics Software Engineer

Kenosha, WI · Remote

$80 - $110/hr

Analyze and interpret small-molecule and drug discovery datasets using advanced computational biology, bioinformatics, and cheminformatics methods. * Curate, annotate, and validate chemical and ...

micro1 AI

Bioinformatics Software Engineer

Madison, WI · Remote

$80 - $110/hr

Analyze and interpret small-molecule and drug discovery datasets using advanced computational biology, bioinformatics, and cheminformatics methods. * Curate, annotate, and validate chemical and ...

micro1 AI

Bioinformatics Software Engineer

Milwaukee, WI · Remote

$80 - $110/hr

Analyze and interpret small-molecule and drug discovery datasets using advanced computational biology, bioinformatics, and cheminformatics methods. * Curate, annotate, and validate chemical and ...

VITO Research

WI · On-site

$79.93 - $125.60/hr

We are looking for an experienced Senior Research Software Engineer to lead the design and ... You hold a Master degree in bioinformatics, computational biology, genomics, computer science, data ...

JDA Software

WI · On-site

$153 - $190/hr

Job Details Role: Sr Staff Software Engineer Location: DALLAS TX ( hybrid role) NO 100% REMOTE, has to relocate if not LOCAL to Dallas. Overview About Blue Yonder Blue Yonder is a Leading AI-driven ...

Schneider

Senior Software Engineer

Green Bay, WI

$119K - $157K/yr

Senior Software Engineer Work model:On-Site Location:Green Bay, WI, USA Shift:First shift Job level:Individual Contributor Schedule:Full time; Mon-Fri 1st Shift Apply now Get job alerts Job overview:

Groundworks Operations, LLC

WI · On-site

$120 - $150/hr

The Senior Software Engineer at Groundworks will play a key role in designing, developing, and maintaining high-quality software solutions that support the company's business goals. This position ...

Husch Blackwell Llp

Senior Software Engineer

Madison, WI · On-site +1

$123K - $162K/yr

The Senior Software Engineer designs, builds, and maintains the technical systems and application infrastructure that power high-quality, human-centered information experiences. This role is ...

Husch Blackwell Llp

Senior Software Engineer

Milwaukee, WI · On-site +1

$120K - $158K/yr

The Senior Software Engineer designs, builds, and maintains the technical systems and application infrastructure that power high-quality, human-centered information experiences. This role is ...

Husch Blackwell LLP

Senior Software Engineer

Madison, WI · On-site +1

$123K - $162K/yr

The Senior Software Engineer designs, builds, and maintains the technical systems and application infrastructure that power high-quality, human-centered information experiences. This role is ...

Husch Blackwell LLP

Senior Software Engineer

Milwaukee, WI · On-site +1

$120K - $158K/yr

The Senior Software Engineer designs, builds, and maintains the technical systems and application infrastructure that power high-quality, human-centered information experiences. This role is ...

IMG LIVE

Senior Software Engineer

Oregon, WI · On-site

$131.25 - $175/hr

Senior Software Engineer**WME is building the next generation of internal platforms that power one of the world's leading entertainment companies.We're looking for a Senior Software Engineer who ...

ULINE

Senior Software Engineer

Pleasant Prairie, WI · On-site

$118K - $156K/yr

Senior Software Engineer Corporate Headquarters 12575 Uline Drive, Pleasant Prairie, WI 53158 Are you an expert at developing software solutions from start to finish? Then you belong at Uline! Join ...

ULINE

Senior Software Engineer

Milwaukee, WI · On-site

$120K - $159K/yr

Senior Software Engineer Corporate Headquarters 12575 Uline Drive, Pleasant Prairie, WI 53158 Are you an expert at developing software solutions from start to finish? Then you belong at Uline! Join ...

Uline

Senior Software Engineer

Pleasant Prairie, WI · On-site

$118K - $156K/yr

Senior Software Engineer Corporate Headquarters 12575 Uline Drive, Pleasant Prairie, WI 53158 Are you an expert at developing software solutions from start to finish? Then you belong at Uline! Join ...

ULINE

Senior Software Engineer

Kenosha, WI · On-site

$119K - $157K/yr

Senior Software Engineer Corporate Headquarters 12575 Uline Drive, Pleasant Prairie, WI 53158 Are you an expert at developing software solutions from start to finish? Then you belong at Uline! Join ...

ULINE

Senior Software Engineer

Pleasant Prairie, WI · On-site

$118K - $156K/yr

Senior Software Engineer Corporate Headquarters 12575 Uline Drive, Pleasant Prairie, WI 53158 Are you an expert at developing software solutions from start to finish? Then you belong at Uline! Join ...

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All JobsBioinformatics Software Engineer JobsSenior Bioinformatics Software Engineer JobsSenior Bioinformatics Software Engineer Jobs in Wisconsin

Senior Bioinformatics Software Engineer information

See Wisconsin salary details

$85.3K

$103.2K

$120.6K

How much do senior bioinformatics software engineer jobs pay per year?

As of Aug 26, 2026, the average yearly pay for senior bioinformatics software engineer in Wisconsin is $103,228.00, according to ZipRecruiter salary data. Most workers in this role earn between $95,400.00 and $111,000.00 per year, depending on experience, location, and employer.

What does a senior bioinformatics software engineer do?

A Senior Bioinformatics Software Engineer designs, develops, and maintains software tools and pipelines to analyze biological data, such as genomic or proteomic information. They work closely with scientists and researchers to understand data requirements and translate them into efficient, scalable computational solutions. Their responsibilities often include coding, troubleshooting, optimizing algorithms, as well as mentoring junior engineers and contributing to project planning. Senior engineers are expected to have strong programming skills, a solid understanding of bioinformatics concepts, and experience working with large biological datasets.

What are the key skills and qualifications needed to thrive as a senior bioinformatics software engineer?

To thrive as a Senior Bioinformatics Software Engineer, you need a strong background in computer science, biology, and data analysis, often supported by an advanced degree in bioinformatics or a related field. Expertise with programming languages (such as Python, R, or Java), cloud computing, bioinformatics tools, and version control systems is typically required, along with experience using databases and relevant software frameworks. Strong problem-solving skills, collaboration, and effective communication are crucial soft skills for working with multidisciplinary teams and presenting complex data. These combined skills enable the effective development and maintenance of robust software tools that support cutting-edge biological research and data-driven discoveries.

How does a senior bioinformatics software engineer typically collaborate with cross-functional teams in a research or clinical setting?

Senior Bioinformatics Software Engineers frequently work alongside biologists, data scientists, and clinicians to develop and maintain computational pipelines for data analysis. They play a key role in translating complex biological questions into scalable software solutions, often leading code reviews, mentoring junior developers, and ensuring data integrity. Regular meetings and clear communication are vital, as the role requires aligning technical development with scientific goals and regulatory requirements. This collaborative environment offers opportunities to influence project direction and contribute to impactful discoveries.

What is the difference between Senior Bioinformatics Software Engineer vs Bioinformatics Software Engineer?

AspectSenior Bioinformatics Software EngineerBioinformatics Software Engineer
Required CredentialsBachelor's or Master's in Bioinformatics, Computer Science, or related field; experience in software development and bioinformatics toolsBachelor's or Master's in Bioinformatics, Computer Science, or related field; less emphasis on extensive experience
Work EnvironmentResearch labs, biotech companies, healthcare institutions, often leading projectsResearch teams, biotech firms, academic settings, supporting bioinformatics analysis
Employer & Industry UsageUsed in biotech, pharma, healthcare, research institutionsCommon in similar industries, often as entry to mid-level roles

The main difference between a Senior Bioinformatics Software Engineer and a Bioinformatics Software Engineer lies in experience and responsibility. Senior roles typically require more advanced skills, leadership, and project management, while entry-level roles focus on supporting bioinformatics analysis and software development. Both roles are vital in biotech and research industries, but senior positions involve greater oversight and strategic input.

What are the most commonly searched types of Bioinformatics Software Engineer jobs in Wisconsin?

The most popular types of Bioinformatics Software Engineer jobs in Wisconsin are:

What cities in Wisconsin are hiring for Senior Bioinformatics Software Engineer jobs?

Cities in Wisconsin with the most Senior Bioinformatics Software Engineer job openings:

Senior Bioinformatics Software Engineer jobs near you

Bioinformatics Software Engineer

Green Bay, WI • Remote

micro1 AI
Software Development • 11 - 50 employees
Learn more about micro1 AIexternal

$80 - $110/hr

Part-time

Posted 23 days ago

Job description

Role Title: Computational Biology & Cheminformatics Expert


Role Type: Contractor


Location: Remote


micro1 is engaging Computational Biology & Cheminformatics Experts to contribute their expertise to a customer’s computational drug discovery project. In this role, you'll apply your expertise to help train next-generation AI systems. Your work will shape how models learn, reason, and perform through high-quality, real-world input. No prior experience in AI is required — your domain knowledge is what matters.


Scope of Work

  1. Analyze and interpret small-molecule and drug discovery datasets using advanced computational biology, bioinformatics, and cheminformatics methods.
  2. Curate, annotate, and validate chemical and biological datasets (e.g., ChEMBL, PubChem, DrugBank) to support AI-driven discovery platforms.
  3. Evaluate compound-target interactions, ADMET properties, and lead optimization strategies by integrating chemical, biological, and clinical data sources.
  4. Provide expert insights on structure-activity and structure-property relationships (SAR/SPR), medicinal chemistry approaches, and experimental design considerations.
  5. Build and implement code-based benchmark tasks (e.g., terminal/CLI-based environments) that reflect realistic computational drug discovery scenarios.
  6. Develop reproducible environments (e.g., using Docker) and automated testing pipelines to ensure task correctness and solvability.
  7. Assess and review AI-generated outputs for scientific rigor, accuracy, and practical relevance, delivering detailed written feedback and recommendations.


Preferred Qualifications

  1. Advanced expertise in Computational Biology, Cheminformatics, Medicinal Chemistry, Biochemistry, or related fields; advanced degree (PhD, MSc, PharmD) highly valued but not strictly required.
  2. Strong coding proficiency in Python (beyond analysis scripts), with hands-on experience building tools, pipelines, or testable code; familiarity with Git, GitHub, and Docker.
  3. Extensive experience with cheminformatics toolkits and platforms such as RDKit, KNIME, Schrödinger, OpenEye, or MOE.
  4. Proven track record in small-molecule drug discovery, SAR/QSAR evaluation, ADMET prediction, or virtual screening workflows.
  5. Comfort working with public chemical and bioactivity databases and integrating diverse datasets for scientific analysis.
  6. Demonstrated ability to clearly communicate complex chemical and biological concepts in written feedback and reports.
  7. Experience participating in multidisciplinary and/or remote projects; familiarity with AI-assisted coding tools is a plus.

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