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Senior Bioinformatics Software Engineer Jobs (NOW HIRING)

BiomeSense

Senior Bioinformatics Engineer

Chicago, IL · On-site

$125K - $200K/yr

Senior Bioinformatics Engineer Compensation: $125K - $200K base + 0.25% - 0.5% equity stock options ... Position Help build our MetaBiome platform, a software solution for collecting, curating ...

NYULMC

Senior Bioinformatics Programmer

New York, NY · On-site

Position Summary: We have an exciting opportunity to join our team as a Sr. Bioinformatics ... software engineering concepts • Knowledge of algorithms, data structures, machine learning • ...

Jobgether

Our partner is looking for a Senior Bioinformatics Developer based in Netherlands. This role offers ... The position combines software engineering, computational biology, and data analysis to solve ...

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Senior Bioinformatics Software Engineer information

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$102.3K

$119.5K

How much do senior bioinformatics software engineer jobs pay per year?

As of Jul 18, 2026, the average yearly pay for senior bioinformatics software engineer in the United States is $102,271.00, according to ZipRecruiter salary data. Most workers in this role earn between $94,500.00 and $110,000.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Senior Bioinformatics Software Engineer, and why are they important?

To thrive as a Senior Bioinformatics Software Engineer, you need a strong background in computer science, biology, and data analysis, often supported by an advanced degree in bioinformatics or a related field. Expertise with programming languages (such as Python, R, or Java), cloud computing, bioinformatics tools, and version control systems is typically required, along with experience using databases and relevant software frameworks. Strong problem-solving skills, collaboration, and effective communication are crucial soft skills for working with multidisciplinary teams and presenting complex data. These combined skills enable the effective development and maintenance of robust software tools that support cutting-edge biological research and data-driven discoveries.

How does a Senior Bioinformatics Software Engineer typically collaborate with cross-functional teams in a research or clinical setting?

Senior Bioinformatics Software Engineers frequently work alongside biologists, data scientists, and clinicians to develop and maintain computational pipelines for data analysis. They play a key role in translating complex biological questions into scalable software solutions, often leading code reviews, mentoring junior developers, and ensuring data integrity. Regular meetings and clear communication are vital, as the role requires aligning technical development with scientific goals and regulatory requirements. This collaborative environment offers opportunities to influence project direction and contribute to impactful discoveries.

What does a Senior Bioinformatics Software Engineer do?

A Senior Bioinformatics Software Engineer designs, develops, and maintains software tools and pipelines to analyze biological data, such as genomic or proteomic information. They work closely with scientists and researchers to understand data requirements and translate them into efficient, scalable computational solutions. Their responsibilities often include coding, troubleshooting, optimizing algorithms, as well as mentoring junior engineers and contributing to project planning. Senior engineers are expected to have strong programming skills, a solid understanding of bioinformatics concepts, and experience working with large biological datasets.

What is the difference between Senior Bioinformatics Software Engineer vs Bioinformatics Software Engineer?

AspectSenior Bioinformatics Software EngineerBioinformatics Software Engineer
Required CredentialsBachelor's or Master's in Bioinformatics, Computer Science, or related field; experience in software development and bioinformatics toolsBachelor's or Master's in Bioinformatics, Computer Science, or related field; less emphasis on extensive experience
Work EnvironmentResearch labs, biotech companies, healthcare institutions, often leading projectsResearch teams, biotech firms, academic settings, supporting bioinformatics analysis
Employer & Industry UsageUsed in biotech, pharma, healthcare, research institutionsCommon in similar industries, often as entry to mid-level roles

The main difference between a Senior Bioinformatics Software Engineer and a Bioinformatics Software Engineer lies in experience and responsibility. Senior roles typically require more advanced skills, leadership, and project management, while entry-level roles focus on supporting bioinformatics analysis and software development. Both roles are vital in biotech and research industries, but senior positions involve greater oversight and strategic input.

More about Senior Bioinformatics Software Engineer jobs
What cities are hiring for Senior Bioinformatics Software Engineer jobs? Cities with the most Senior Bioinformatics Software Engineer job openings:
What are the most commonly searched types of Bioinformatics Software Engineer jobs? The most popular types of Bioinformatics Software Engineer jobs are:
What states have the most Senior Bioinformatics Software Engineer jobs? States with the most job openings for Senior Bioinformatics Software Engineer jobs include:
What job categories do people searching Senior Bioinformatics Software Engineer jobs look for? The top searched job categories for Senior Bioinformatics Software Engineer jobs are:
Senior Bioinformatics Software Engineer jobs near you
Infographic showing various Senior Bioinformatics Software Engineer job openings in the United States as of July 2026, with employment types broken down into 3% Locum Tenens, 5% As Needed, 66% Full Time, 8% Part Time, 1% Contract, and 17% Nights. Highlights an 82% Physical, 2% Hybrid, and 16% Remote job distribution, with an average salary of $102,271 per year, or $49.2 per hour.
Bioinformatics Software Engineer

Bioinformatics Software Engineer

MyOme

San Francisco, CA

$130K - $160K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 27 days ago

Job description

MyOme's mission is to provide clinically actionable genetic information to patients throughout their lives. We combine clinical-grade whole genome sequencing, advanced AI methods for genome interpretation, and seamless digital tools for doctors and patients to order and access results. Our team is composed of seasoned entrepreneurs, scientists, and operators, and we're backed by top-tier investors.

Position Overview:

MyOme is looking for a talented and experienced bioinformatics software engineer to join the team. As a Bioinformatics Software Engineer, you will build scalable, cloud-based pipelines that power genomic and clinical data analysis in a real-world healthcare setting. You will combine strong engineering practices with bioinformatics expertise to develop reliable, production-grade systems that support clinical decision-making and advance precision medicine.

What You'll Do:

  • Build, test, and maintain a suite of robust bioinformatics tools, workflows, and analysis modules.
  • Work in a team to scope, define, and articulate solutions to complex computing and information management challenges at the forefront of modern bioinformatics.
  • Contribute to the architecture and operations of our computing infrastructure.
  • Contribute to the team through code reviews and design discussions
  • Participate in agile development processes, including sprint planning, retrospectives, and continuous improvement
  • Balance quick wins with long-term technical sustainability
  • As a well-rounded engineer, participate in all aspects of the development process and be interested in our mission.

What You'll Need:

  • No specific degree required - if you can do the work well and collaborate with humility, we want to hear from you.
  • 2+ years of experience building and managing bioinformatics workflows (e.g., Nextflow, Snakemake, WDL, CWL).
  • Proven experience optimizing and scaling bioinformatics pipelines for performance and reliability.
  • Proficient in Python, with bonus points for experience in other programming languages.
  • First-hand experience working with bioinformatics tools, databases, and file formats used in sequence analysis.
  • Comfortable with modern development practices - version control, unit testing, CI/CD, and code reviews.
  • Hands-on experience with Linux/Unix and cloud infrastructure (AWS, Docker, Kubernetes, etc.).
  • Thrive in a fast-moving startup - you know when to prototype quickly and when to build production-grade systems.

Location, Compensation, and Benefits:

  • Location: Hybrid role, 2 days a week onsite at our San Francisco, CA office (near Montgomery BART). Occasional travel required for team meetings.
  • Compensation: Annual base salary range of $130,000 - $160,000, based on experience.
San Francisco Bay Area pay range
$130,000—$160,000 USD

Benefits:

  • Comprehensive healthcare coverage (Health, Dental, and Vision)
  • 401K
  • Unlimited PTO
  • Professional development opportunities
  • Company-sponsored off-sites and team meals during in-person meetings
  • Direct access to company leadership and the opportunity for career growth

Diversity, Inclusion, and Equal Opportunity:
MyOme values diversity in all forms. We believe that diverse perspectives drive better science and better patient outcomes. We are an Equal Opportunity Employer committed to creating an inclusive workplace that empowers every individual.

Why Work at MyOme?
Join us if you:

  • Want to make an impact at the intersection of healthcare and technology, changing the way people engage with their health at the genetic level
  • Enjoy rolling up your sleeves, taking initiative, and being empowered to lead
  • Value humility, transparency, and collaborative problem-solving
  • Thrive in fast-moving, dynamic environments with smart, driven teammates
  • Appreciate competitive compensation, meaningful equity, and excellent benefits

Learn More: myome.com

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About MyOme

Sourced by ZipRecruiter

Industry

Biotechnology research and development

Company size

11 - 50 Employees

Headquarters location

Palo Alto, CA, US

Year founded

2017

View All MyOme Jobs