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Senior Bioinformatics Software Engineer Jobs (NOW HIRING)

MyOme

Bioinformatics Software Engineer

San Francisco, CA · On-site

$130K - $160K/yr

As a Bioinformatics Software Engineer, you will build scalable, cloud-based pipelines that power genomic and clinical data analysis in a real-world healthcare setting. You will combine strong ...

BiomeSense

Senior Bioinformatics Engineer

Chicago, IL · On-site

$125K - $200K/yr

Senior Bioinformatics Engineer Compensation: $125K - $200K base + 0.25% - 0.5% equity stock options ... Position Help build our MetaBiome platform, a software solution for collecting, curating ...

NYULMC

Senior Bioinformatics Programmer

New York, NY · On-site

Position Summary: We have an exciting opportunity to join our team as a Sr. Bioinformatics ... software engineering concepts • Knowledge of algorithms, data structures, machine learning • ...

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Senior Bioinformatics Software Engineer information

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How much do senior bioinformatics software engineer jobs pay per year?

As of Jun 27, 2026, the average yearly pay for senior bioinformatics software engineer in the United States is $102,271.00, according to ZipRecruiter salary data. Most workers in this role earn between $94,500.00 and $110,000.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Senior Bioinformatics Software Engineer, and why are they important?

To thrive as a Senior Bioinformatics Software Engineer, you need a strong background in computer science, biology, and data analysis, often supported by an advanced degree in bioinformatics or a related field. Expertise with programming languages (such as Python, R, or Java), cloud computing, bioinformatics tools, and version control systems is typically required, along with experience using databases and relevant software frameworks. Strong problem-solving skills, collaboration, and effective communication are crucial soft skills for working with multidisciplinary teams and presenting complex data. These combined skills enable the effective development and maintenance of robust software tools that support cutting-edge biological research and data-driven discoveries.

How does a Senior Bioinformatics Software Engineer typically collaborate with cross-functional teams in a research or clinical setting?

Senior Bioinformatics Software Engineers frequently work alongside biologists, data scientists, and clinicians to develop and maintain computational pipelines for data analysis. They play a key role in translating complex biological questions into scalable software solutions, often leading code reviews, mentoring junior developers, and ensuring data integrity. Regular meetings and clear communication are vital, as the role requires aligning technical development with scientific goals and regulatory requirements. This collaborative environment offers opportunities to influence project direction and contribute to impactful discoveries.

What does a Senior Bioinformatics Software Engineer do?

A Senior Bioinformatics Software Engineer designs, develops, and maintains software tools and pipelines to analyze biological data, such as genomic or proteomic information. They work closely with scientists and researchers to understand data requirements and translate them into efficient, scalable computational solutions. Their responsibilities often include coding, troubleshooting, optimizing algorithms, as well as mentoring junior engineers and contributing to project planning. Senior engineers are expected to have strong programming skills, a solid understanding of bioinformatics concepts, and experience working with large biological datasets.

What is the difference between Senior Bioinformatics Software Engineer vs Bioinformatics Software Engineer?

AspectSenior Bioinformatics Software EngineerBioinformatics Software Engineer
Required CredentialsBachelor's or Master's in Bioinformatics, Computer Science, or related field; experience in software development and bioinformatics toolsBachelor's or Master's in Bioinformatics, Computer Science, or related field; less emphasis on extensive experience
Work EnvironmentResearch labs, biotech companies, healthcare institutions, often leading projectsResearch teams, biotech firms, academic settings, supporting bioinformatics analysis
Employer & Industry UsageUsed in biotech, pharma, healthcare, research institutionsCommon in similar industries, often as entry to mid-level roles

The main difference between a Senior Bioinformatics Software Engineer and a Bioinformatics Software Engineer lies in experience and responsibility. Senior roles typically require more advanced skills, leadership, and project management, while entry-level roles focus on supporting bioinformatics analysis and software development. Both roles are vital in biotech and research industries, but senior positions involve greater oversight and strategic input.

More about Senior Bioinformatics Software Engineer jobs
What cities are hiring for Senior Bioinformatics Software Engineer jobs? Cities with the most Senior Bioinformatics Software Engineer job openings:
What are the most commonly searched types of Bioinformatics Software Engineer jobs? The most popular types of Bioinformatics Software Engineer jobs are:
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Senior Bioinformatics Software Engineer jobs near you
Infographic showing various Senior Bioinformatics Software Engineer job openings in the United States as of June 2026, with employment types broken down into 1% As Needed, 80% Full Time, 16% Part Time, and 3% Contract. Highlights an 89% Physical, 4% Hybrid, and 7% Remote job distribution, with an average salary of $102,271 per year, or $49.2 per hour.

Bioinformatics Software Engineer

AccuraGen

San Jose, CA

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 22 days ago

Job description

As a Bioinformatics Software Engineer at AccuraGen, you will develop, optimize, and maintain bioinformatics pipelines utilizing AWS infrastructure and Nextflow workflow management systems. Your contributions will directly impact innovative scientific discoveries and product development. You'll collaborate closely with scientists, engineers, and researchers, contributing your technical expertise to streamline processes, maintain automation, and drive our bioinformatics capabilities forward.

Responsibilities:

  • Design, implement, and develop tests and documentation for established robust bioinformatics pipelines.
  • Optimize computational workflows for high-performance execution and reproducible data analysis.
  • Maintain, monitor, and improve pipeline automation to ensure smooth operational workflows.
  • Manage GitHub repositories, oversee version control, and streamline the software release process.
  • Develop and manage infrastructure on AWS to ensure scalability, reliability, and efficiency.
  • Collaborate with cross-functional teams to integrate bioinformatics solutions.
  • Proactively identify opportunities to enhance infrastructure efficiency and security.

Requirements

Qualifications:

    • Bachelor's degree or higher in Bioinformatics, Computational Biology, Computer Science, or a related field. with at least 3+ years of working experience out of college.
    • Experience with bioinformatics workflow development and optimization, particularly using Nextflow.
    • Experience developing software following best practices, including comprehensive testing and clear documentation.
    • Proficiency in scripting languages (Python, Bash) and familiarity with container technologies (Docker, Kubernetes).
    • Hands-on experience with AWS cloud computing services (EC2, S3, Batch, Lambda).
    • Excellent communication and collaborative skills.

Preferred Qualifications:

  •  Familiarity with CI/CD practices.
  • Experience with infrastructure-as-code (Terraform, CloudFormation).

Benefits

  • Health Care Plan (Medical, Dental & Vision)
  • Retirement Plan (401k, IRA)
  • Paid Time Off (Vacation, Sick & Public Holidays)

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