ZipRecruiter

Log In

1

Senior Bioinformatics Software Engineer Jobs in Ohio

micro1 AI

Bioinformatics Software Engineer

Cincinnati, OH · Remote

$80 - $110/hr

Analyze and interpret small-molecule and drug discovery datasets using advanced computational biology, bioinformatics, and cheminformatics methods. * Curate, annotate, and validate chemical and ...

micro1 AI

Bioinformatics Software Engineer

Columbus, OH · Remote

$80 - $110/hr

Analyze and interpret small-molecule and drug discovery datasets using advanced computational biology, bioinformatics, and cheminformatics methods. * Curate, annotate, and validate chemical and ...

micro1 AI

Bioinformatics Software Engineer

Toledo, OH · Remote

$80 - $110/hr

Analyze and interpret small-molecule and drug discovery datasets using advanced computational biology, bioinformatics, and cheminformatics methods. * Curate, annotate, and validate chemical and ...

micro1 AI

Bioinformatics Software Engineer

Dayton, OH · Remote

$80 - $110/hr

Analyze and interpret small-molecule and drug discovery datasets using advanced computational biology, bioinformatics, and cheminformatics methods. * Curate, annotate, and validate chemical and ...

micro1 AI

Bioinformatics Software Engineer

Akron, OH · Remote

$80 - $110/hr

Analyze and interpret small-molecule and drug discovery datasets using advanced computational biology, bioinformatics, and cheminformatics methods. * Curate, annotate, and validate chemical and ...

micro1 AI

Bioinformatics Software Engineer

Cleveland, OH · Remote

$80 - $110/hr

Analyze and interpret small-molecule and drug discovery datasets using advanced computational biology, bioinformatics, and cheminformatics methods. * Curate, annotate, and validate chemical and ...

LayerZero Power Systems Inc

Senior Software Engineer

Aurora, OH · On-site

$114K - $151K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

Job Type Full-time Description Senior Software Engineer About us: LayerZero Power Systems, Inc. is a leader in power management products for mission and process critical business applications. Our ...

LayerZero Power Systems Inc

Senior Software Engineer

Aurora, OH

$114K - $151K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

Description Senior Software Engineer About us: LayerZero Power Systems, Inc. is a leader in power management products for mission and process critical business applications. Our customer base is ...

LayerZero Power Systems, LLC.

Senior Software Engineer

Aurora, OH · On-site

$114K - $151K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

Senior Software Engineer About us: LayerZero Power Systems, Inc. is a leader in power management products for mission and process critical business applications. Our customer base is comprised of ...

LayerZero Power Systems Inc

Senior Software Engineer

Aurora, OH · On-site

$114K - $151K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

Job Type Full-time Description Senior Software Engineer About us: LayerZero Power Systems, Inc. is a leader in power management products for mission and process critical business applications. Our ...

Applied Research Solutions

Senior Software Engineer

Dayton, OH · On-site

$115K - $152K/yr

ARS is seeking a Senior Software Engineer to support the U.S. Air Force KC-46 Weapon System Lifecycle (WLC) Program. The selected candidate will provide software engineering expertise across the full ...

Applied Research Solutions

Senior Software Engineer

Dayton, OH · On-site

$115K - $152K/yr

ARS is seeking a Senior Software Engineer to support the U.S. Air Force KC-46 Weapon System Lifecycle (WLC) Program. The selected candidate will provide software engineering expertise across the full ...

Applied Research Solutions

Senior Software Engineer

Dayton, OH · On-site

$119K - $157K/yr

ARS is seeking a Senior Software Engineer to support the U.S. Air Force KC-46 Weapon System Lifecycle (WLC) Program. The selected candidate will provide software engineering expertise across the full ...

Booz Allen Hamilton

Software Engineer, Senior

Dayton, OH · On-site

$86K - $198K/yr

  • Medical

  • Life

  • Retirement

  • PTO

Software Engineer, Senior The Opportunity: Seeking a Senior Software Engineer to lead andsupport Agile design, development, integration and deployment of a mission management softwarefor ...

Parallax Advanced Research

Senior Software Engineer

Beavercreek, OH · On-site

$121K - $148K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Senior Software Engineer Location: On-Site - Dayton At Parallax, we believe in advancing science and serving the public good--and we're looking for team members who do too. If you're ready to support ...

Appliedres

Senior Software Engineer

Dayton, OH · On-site

$120 - $150/hr

Description ARS is seeking a Senior Software Engineer to support the U. S. Air Force KC-46 Weapon System Lifecycle (WLC) Program. The selected candidate will provide software engineering expertise ...

JumpMind, LLC

UK Sr Software Engineer

Columbus, OH · On-site

$115K - $152K/yr

Job Requisition: Sr Software Engineer Requisition Title: Sr Software Engineer Location: UK based, Hybrid from Home & Office Jumpmind is looking for a Sr Software Engineer, who is passionate about ...

next page

Showing results 1-20

All JobsBioinformatics Software Engineer JobsSenior Bioinformatics Software Engineer JobsSenior Bioinformatics Software Engineer Jobs in Ohio

Senior Bioinformatics Software Engineer information

What does a senior bioinformatics software engineer do?

A Senior Bioinformatics Software Engineer designs, develops, and maintains software tools and pipelines to analyze biological data, such as genomic or proteomic information. They work closely with scientists and researchers to understand data requirements and translate them into efficient, scalable computational solutions. Their responsibilities often include coding, troubleshooting, optimizing algorithms, as well as mentoring junior engineers and contributing to project planning. Senior engineers are expected to have strong programming skills, a solid understanding of bioinformatics concepts, and experience working with large biological datasets.

What are the key skills and qualifications needed to thrive as a senior bioinformatics software engineer?

To thrive as a Senior Bioinformatics Software Engineer, you need a strong background in computer science, biology, and data analysis, often supported by an advanced degree in bioinformatics or a related field. Expertise with programming languages (such as Python, R, or Java), cloud computing, bioinformatics tools, and version control systems is typically required, along with experience using databases and relevant software frameworks. Strong problem-solving skills, collaboration, and effective communication are crucial soft skills for working with multidisciplinary teams and presenting complex data. These combined skills enable the effective development and maintenance of robust software tools that support cutting-edge biological research and data-driven discoveries.

How does a senior bioinformatics software engineer typically collaborate with cross-functional teams in a research or clinical setting?

Senior Bioinformatics Software Engineers frequently work alongside biologists, data scientists, and clinicians to develop and maintain computational pipelines for data analysis. They play a key role in translating complex biological questions into scalable software solutions, often leading code reviews, mentoring junior developers, and ensuring data integrity. Regular meetings and clear communication are vital, as the role requires aligning technical development with scientific goals and regulatory requirements. This collaborative environment offers opportunities to influence project direction and contribute to impactful discoveries.

What is the difference between Senior Bioinformatics Software Engineer vs Bioinformatics Software Engineer?

AspectSenior Bioinformatics Software EngineerBioinformatics Software Engineer
Required CredentialsBachelor's or Master's in Bioinformatics, Computer Science, or related field; experience in software development and bioinformatics toolsBachelor's or Master's in Bioinformatics, Computer Science, or related field; less emphasis on extensive experience
Work EnvironmentResearch labs, biotech companies, healthcare institutions, often leading projectsResearch teams, biotech firms, academic settings, supporting bioinformatics analysis
Employer & Industry UsageUsed in biotech, pharma, healthcare, research institutionsCommon in similar industries, often as entry to mid-level roles

The main difference between a Senior Bioinformatics Software Engineer and a Bioinformatics Software Engineer lies in experience and responsibility. Senior roles typically require more advanced skills, leadership, and project management, while entry-level roles focus on supporting bioinformatics analysis and software development. Both roles are vital in biotech and research industries, but senior positions involve greater oversight and strategic input.

What are the most commonly searched types of Bioinformatics Software Engineer jobs in Ohio?

The most popular types of Bioinformatics Software Engineer jobs in Ohio are:

Senior Bioinformatics Software Engineer jobs near you
Infographic showing various Senior Bioinformatics Software Engineer job openings in Ohio as of June 2026, with employment types broken down into 1% As Needed, 82% Full Time, 15% Part Time, and 2% Contract. Highlights an 88% Physical, 4% Hybrid, and 8% Remote job distribution.

Bioinformatics Software Engineer

micro1 AI

Cincinnati, OH • Remote

$80 - $110/hr

Part-time

Posted 17 days ago

Job description

Role Title: Computational Biology & Cheminformatics Expert


Role Type: Contractor


Location: Remote


micro1 is engaging Computational Biology & Cheminformatics Experts to contribute their expertise to a customer’s computational drug discovery project. In this role, you'll apply your expertise to help train next-generation AI systems. Your work will shape how models learn, reason, and perform through high-quality, real-world input. No prior experience in AI is required — your domain knowledge is what matters.


Scope of Work

  1. Analyze and interpret small-molecule and drug discovery datasets using advanced computational biology, bioinformatics, and cheminformatics methods.
  2. Curate, annotate, and validate chemical and biological datasets (e.g., ChEMBL, PubChem, DrugBank) to support AI-driven discovery platforms.
  3. Evaluate compound-target interactions, ADMET properties, and lead optimization strategies by integrating chemical, biological, and clinical data sources.
  4. Provide expert insights on structure-activity and structure-property relationships (SAR/SPR), medicinal chemistry approaches, and experimental design considerations.
  5. Build and implement code-based benchmark tasks (e.g., terminal/CLI-based environments) that reflect realistic computational drug discovery scenarios.
  6. Develop reproducible environments (e.g., using Docker) and automated testing pipelines to ensure task correctness and solvability.
  7. Assess and review AI-generated outputs for scientific rigor, accuracy, and practical relevance, delivering detailed written feedback and recommendations.


Preferred Qualifications

  1. Advanced expertise in Computational Biology, Cheminformatics, Medicinal Chemistry, Biochemistry, or related fields; advanced degree (PhD, MSc, PharmD) highly valued but not strictly required.
  2. Strong coding proficiency in Python (beyond analysis scripts), with hands-on experience building tools, pipelines, or testable code; familiarity with Git, GitHub, and Docker.
  3. Extensive experience with cheminformatics toolkits and platforms such as RDKit, KNIME, Schrödinger, OpenEye, or MOE.
  4. Proven track record in small-molecule drug discovery, SAR/QSAR evaluation, ADMET prediction, or virtual screening workflows.
  5. Comfort working with public chemical and bioactivity databases and integrating diverse datasets for scientific analysis.
  6. Demonstrated ability to clearly communicate complex chemical and biological concepts in written feedback and reports.
  7. Experience participating in multidisciplinary and/or remote projects; familiarity with AI-assisted coding tools is a plus.

Apply