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Senior Bioinformatics Software Engineer Jobs in Virginia

ShortList Recruitment Limited

$121K - $159K/yr

\n \n \n Senior Software Engineer Richmond, VA $150,000 I am hiring for a Senior Full Stack Software Engineer to join a small, specialist software company that supplies innovative software to ...

Gridpoint

Senior Software Engineer

Reston, VA

$127K - $168K/yr

The Senior Software Engineer shall perform with a high degree of independence and expertise to implement solutions for a variety of complex software products/features... both wholly new efforts and ...

Gridpoint

Senior Software Engineer

Reston, VA · On-site

$127K - $168K/yr

The Senior Software Engineer shall perform with a high degree of independence and expertise to implement solutions for a variety of complex software products/features... both wholly new efforts and ...

Thomson Reuters

Senior Software Engineer

Mclean, VA · On-site +1

$123K - $163K/yr

As a Senior Software Engineer , you will also contribute to a variety of areas including: * Leading projects and acting as a mentor to less experienced developers * Collaborating with the TRSS ...

THOMSON REUTERS

Senior Software Engineer

Mclean, VA · On-site

$123K - $163K/yr

As a Senior Software Engineer , you will also contribute to a variety of areas including: * Leading projects and acting as a mentor to less experienced developers * Collaborating with the TRSS ...

GridPoint

Senior Software Engineer

Reston, VA · On-site

$127K - $168K/yr

The Senior Software Engineer will implement solutions for complex software products and features, ensuring high quality through design, implementation, and testing. Responsibilities : • participate ...

TMC Technologies

Senior Software Engineer

King George, VA · On-site

$114K - $150K/yr

Job Title Senior Software Engineer Location King George, VA 22485 US (Primary) Category Engineering Job Type Full-time Career Level Experienced (Non-Manager) Education Bachelor's Degree Travel ...

Key Choice Group

Senior Software Engineer

Richmond, VA · On-site

$90K - $110K/yr

Senior Software Engineer Our client, in the specialty transportation industry, is seeking a Senior Software Engineer to join their team, hit the ground running, and help drive to success.This is a ...

Nalley Consulting

Software Engineer - Sr

Reston, VA · On-site

$129K - $170K/yr

Software Engineer LCAT: Senior Location: Reston, Virginia This position is contingent upon award. Required clearance: TS/SCI with willingness to take CI poly. Candidates with current CI poly taken ...

Exiger

Senior Software Engineer

Mclean, VA · Hybrid

$123K - $163K/yr

Senior Software Engineer Location: McLean, VA or Richmond, VA Work Environment: Hybrid Role Sumary: As a Senior Software Engineer at Exiger, you will be responsible for designing and developing ...

Nalley Consulting

Software Engineer - Sr

Reston, VA · On-site

$129K - $170K/yr

Software Engineer LCAT: Senior Location: Reston, Virginia This position is contingent upon award. Required clearance: TS/SCI with willingness to take CI poly. Candidates with current CI poly taken ...

Piper Companies

Senior Software Engineer

Springfield, VA · On-site

$140K - $160K/yr

As a Senior Software Engineer, you will play a key role in supporting the Geospatial Intelligence Agency (NGA) by designing, developing, and maintaining geospatial intelligence applications. Your ...

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All JobsBioinformatics Software Engineer JobsSenior Bioinformatics Software Engineer JobsSenior Bioinformatics Software Engineer Jobs in Virginia

Senior Bioinformatics Software Engineer information

See Virginia salary details

$83.8K

$101.4K

$118.5K

How much do senior bioinformatics software engineer jobs pay per year?

As of Jul 13, 2026, the average yearly pay for senior bioinformatics software engineer in Virginia is $101,394.00, according to ZipRecruiter salary data. Most workers in this role earn between $93,700.00 and $109,100.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Senior Bioinformatics Software Engineer, and why are they important?

To thrive as a Senior Bioinformatics Software Engineer, you need a strong background in computer science, biology, and data analysis, often supported by an advanced degree in bioinformatics or a related field. Expertise with programming languages (such as Python, R, or Java), cloud computing, bioinformatics tools, and version control systems is typically required, along with experience using databases and relevant software frameworks. Strong problem-solving skills, collaboration, and effective communication are crucial soft skills for working with multidisciplinary teams and presenting complex data. These combined skills enable the effective development and maintenance of robust software tools that support cutting-edge biological research and data-driven discoveries.

How does a Senior Bioinformatics Software Engineer typically collaborate with cross-functional teams in a research or clinical setting?

Senior Bioinformatics Software Engineers frequently work alongside biologists, data scientists, and clinicians to develop and maintain computational pipelines for data analysis. They play a key role in translating complex biological questions into scalable software solutions, often leading code reviews, mentoring junior developers, and ensuring data integrity. Regular meetings and clear communication are vital, as the role requires aligning technical development with scientific goals and regulatory requirements. This collaborative environment offers opportunities to influence project direction and contribute to impactful discoveries.

What does a Senior Bioinformatics Software Engineer do?

A Senior Bioinformatics Software Engineer designs, develops, and maintains software tools and pipelines to analyze biological data, such as genomic or proteomic information. They work closely with scientists and researchers to understand data requirements and translate them into efficient, scalable computational solutions. Their responsibilities often include coding, troubleshooting, optimizing algorithms, as well as mentoring junior engineers and contributing to project planning. Senior engineers are expected to have strong programming skills, a solid understanding of bioinformatics concepts, and experience working with large biological datasets.

What is the difference between Senior Bioinformatics Software Engineer vs Bioinformatics Software Engineer?

AspectSenior Bioinformatics Software EngineerBioinformatics Software Engineer
Required CredentialsBachelor's or Master's in Bioinformatics, Computer Science, or related field; experience in software development and bioinformatics toolsBachelor's or Master's in Bioinformatics, Computer Science, or related field; less emphasis on extensive experience
Work EnvironmentResearch labs, biotech companies, healthcare institutions, often leading projectsResearch teams, biotech firms, academic settings, supporting bioinformatics analysis
Employer & Industry UsageUsed in biotech, pharma, healthcare, research institutionsCommon in similar industries, often as entry to mid-level roles

The main difference between a Senior Bioinformatics Software Engineer and a Bioinformatics Software Engineer lies in experience and responsibility. Senior roles typically require more advanced skills, leadership, and project management, while entry-level roles focus on supporting bioinformatics analysis and software development. Both roles are vital in biotech and research industries, but senior positions involve greater oversight and strategic input.

What are the most commonly searched types of Bioinformatics Software Engineer jobs in Virginia? The most popular types of Bioinformatics Software Engineer jobs in Virginia are:
What are popular job titles related to Senior Bioinformatics Software Engineer jobs in Virginia? For Senior Bioinformatics Software Engineer jobs in Virginia, the most frequently searched job titles are:
What job categories do people searching Senior Bioinformatics Software Engineer jobs in Virginia look for? The top searched job categories for Senior Bioinformatics Software Engineer jobs in Virginia are:
What cities in Virginia are hiring for Senior Bioinformatics Software Engineer jobs? Cities in Virginia with the most Senior Bioinformatics Software Engineer job openings:
Senior Bioinformatics Software Engineer jobs near you
Infographic showing various Senior Bioinformatics Software Engineer job openings in Virginia as of July 2026, with employment types broken down into 3% Locum Tenens, 5% As Needed, 65% Full Time, 8% Part Time, 1% Contract, and 18% Nights. Highlights an 82% Physical, 2% Hybrid, and 16% Remote job distribution, with an average salary of $101,394 per year, or $48.7 per hour.
Software Engineer with Security Clearance

Software Engineer with Security Clearance

Blackhawk Enterprise Incorporated

Charlottesville, VA • On-site

$109K - $131K/yr

Other

Re-posted 12 days ago

Job description

About the Role
We are seeking an experienced Senior Data Engineer to lead the design, development, and maintenance of our mission-critical data infrastructure, with a focus on bioinformatics and the processing of large-scale genomic data. This role requires a hands-on engineer who can architect robust data solutions, establish best practices for data management, and ensure the scalability and reliability of systems supporting secure government operations. You will be responsible for mentoring team members and driving technical excellence across our data ecosystem.
Primary Responsibilities
Design, build, and maintain scalable, reliable, and performant data pipelines for bioinformatics and genomic data.
Architect and implement data models and database schemas to meet application and analytics requirements.
Lead technical decision-making for the evolution and modernization of our data technology stack.
Establish and enforce data engineering standards, best practices, and architectural patterns.
Mentor junior and mid-level engineers through code reviews, pair programming, and technical guidance.
Optimize and scale our data infrastructure, including microservices, databases, and real-time data streams.
Ensure security compliance and implement secure data handling practices for classified environments.
Troubleshoot and resolve complex production issues across distributed data systems.
Required Technical Skills
Core Languages: Expert-level proficiency in Python and/or Javascript.
Scientific Data Expertise:
Proven experience in bioinformatics, scientific data management, or a related domain involving the processing and analysis of large-scale datasets.
Data Engineering & Processing:
Workflow Orchestration: Deep experience with tools like Apache Airflow, Prefect, or Dagster.
Big Data Frameworks: Hands-on experience with processing frameworks such as Apache Spark.
Stream & Message Brokers: Experience with real-time data streaming using Apache Kafka, RabbitMQ, AWS SQS/SNS, or Azure Service Bus.
Data Storage & Databases:
SQL Databases: Expertise in relational databases (PostgreSQL, MySQL, Oracle) including advanced query optimization and schema design.
Object Stores?
Search & Indexing: Familiarity with search engines like Elasticsearch or OpenSearch.
Cloud & Infrastructure:
Cloud Platforms: Strong experience with services from AWS, Azure, or GCP.
DevOps: Experience with automation tools like Jenkins, GitLab CI/CD, or GitHub Actions as well as infrastructure tools like Helm and Terraform.
Preferred Qualifications
Experience designing event-driven architectures and microservices.
Knowledge of data governance, data quality, and observability frameworks.
Background in migrating legacy data systems to modern, scalable architectures.
Deep understanding of database performance tuning: indexing, partitioning, and connection pooling.
Experience with government security compliance (STIG, ATO, FedRAMP).
Front-end experience with frameworks like React, Vue, or Angular is a plus but not required.
Soft Skills
Strong communication skills for technical documentation and cross-team collaboration.
Ability to balance technical debt with feature delivery in a pragmatic way.
Experience leading technical discussions and making architectural decisions.
Comfortable working in an Agile/Scrum environment.
Education & Experience
Bachelor's degree in Computer Science, Bioinformatics, Engineering, or a related field (or equivalent experience).
7+ years of professional software/data engineering experience.
3+ years in a senior or lead engineering role focused on data systems.
Active security clearance or ability to obtain one (required for DoD work).

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