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Senior Bioinformatics Software Engineer Jobs in Virginia

Platinum Technologies

Senior Software Engineer

Herndon, VA · On-site

$126K - $166K/yr

The Senior Software Engineer serves as a key contributor to the design, development, and sustainment of mission-critical software solutions that enable semantic data integration, knowledge management ...

Zel Technologies LLC

Sr. Software Engineer

Dahlgren, VA · On-site

$124K - $164K/yr

The Sr Software Engineer will be responsible for the design, development, testing, and documentation of complex software systems, contributing across the full software lifecycle and working with ...

Xpand Corp

Senior Software Engineer

Herndon, VA · On-site

$150K - $170K/yr

We are seeking a Senior Software Engineer to become an integral part of our team! You will be responsible for designing, building and maintaining web applications in a .NET environment.

Xpand Corp

Senior Software Engineer

Herndon, VA · On-site

$150K - $170K/yr

We are seeking a Senior Software Engineer to become an integral part of our team! You will be responsible for designing, building and maintaining web applications in a .NET environment.

MasterCard

Senior Software Engineer

Arlington, VA

$140K - $185K/yr

Title and Summary Senior Software Engineer Who is Mastercard? Mastercard is a global technology company in the payments industry. Our mission is to connect and power an inclusive digital economy that ...

Teknowleap, Inc

Senior Software Engineer

Sterling, VA · On-site

$123K - $163K/yr

SENIOR SOFTWARE ENGINEER (5 positions offered) to design, develop and code applications using Java and Scala; Integrate backend software applications using Postgres and NoSQL databases; Create ...

Nalley Consulting

Software Engineer - Sr

Reston, VA · On-site

$120 - $150/hr

Software Engineer LCAT: Senior Location: Reston, Virginia This position is contingent upon award. Required clearance: TS/SCI with willingness to take CI poly. Candidates with current CI poly taken ...

IC-CAP LLC

Senior Software Engineer 112-080

Chantilly, VA · On-site

$125K - $165K/yr

Software Engineer (Senior-Level) : Overall Assignment Description : Senior-level Software Engineer assist in leading the design and development of software solutions for complex applications problems ...

Astrion

Senior Software Engineer

Dahlgren, VA

$150K - $190K/yr

Overview Senior Software Engineer Location: Dahlgren, VA Job Status: Full Time Clearance: Secret Salary: $150,000 to $190,000 SEG, an Astrion company, is seeking a Senior Software Engineer to add to ...

Astrion

Senior Software Engineer

Dahlgren, VA · On-site

$150K - $190K/yr

Overview Senior Software Engineer Location: Dahlgren, VA Job Status: Full Time Clearance: Secret Salary: $150,000 to $190,000 SEG, an Astrion company, is seeking a Senior Software Engineer to add to ...

Phase2 Technology

Software Engineer, Senior

Mclean, VA · On-site

$86.80 - $198/hr

We're looking for a passionate Senior Full-Stack Software Engineer to work with a fast-paced, highly collaborative software development team building and launching capability for Enterprise web-based ...

Mastercard, Inc.

Senior Software Engineer

Arlington, VA · On-site

$140K - $185K/yr

Title and Summary Senior Software Engineer Who is Mastercard? Mastercard is a global technology company in the payments industry. Our mission is to connect and power an inclusive digital economy that ...

Zel Technologies

Sr. Software Engineer

Dahlgren, VA · On-site

$140K - $160K/yr

The Sr Software Engineer will support the design, development, testing, and documentation of complex software systems for Department of Defense (DoD) programs. This role requires extensive experience ...

MasterCard

Senior Software Engineer

Arlington, VA · Hybrid

$140K - $185K/yr

Title and Summary Senior Software Engineer Overview: The Accelerators group within Mastercard's Business & Market Insights (B&MI) Platform Engineering organization is seeking a Senior Software ...

Socket.dev

Senior Software Engineer

Arrington, VA · On-site

$114 - $273/hr

The Senior Software Engineer will be part of a multi-discipline team focused on the DOW's initiatives in support of tactical capability development for Navy surface and unmanned (UxVs) platforms and ...

New

Alarm.com

Senior Software Engineer

Tysons Corner, VA

$123K - $162K/yr

Senior Software Engineer - Access Control Are you ready to redefine access control and develop cutting-edge security solutions that make businesses smarter and safer? Do you enjoy leading technical ...

Boeing

Senior Software Engineer

Chantilly, VA

$125K - $165K/yr

Senior Software Engineer Company: The Boeing Company Boeing Defense, Space & Security (BDS) has an exciting opportunity for a Senior Software Engineer to join the National Systems Programs (NSP ...

Boeing

Senior Software Engineer

Chantilly, VA · On-site

$125K - $165K/yr

Senior Software Engineer Company: The Boeing Company Boeing Defense, Space & Security (BDS) has an exciting opportunity for a Senior Software Engineer to join the National Systems Programs (NSP ...

Redhorse Corporation

Senior Software Engineer

Quantico, VA · On-site

$132K - $174K/yr

They are seeking a Senior Software Engineer to join their Cyber Analytics team, where the role involves designing and sustaining mission-critical software that impacts national security and building ...

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All JobsBioinformatics Software Engineer JobsSenior Bioinformatics Software Engineer JobsSenior Bioinformatics Software Engineer Jobs in Virginia

Senior Bioinformatics Software Engineer information

See Virginia salary details

$83.8K

$101.4K

$118.5K

How much do senior bioinformatics software engineer jobs pay per year?

As of Aug 9, 2026, the average yearly pay for senior bioinformatics software engineer in Virginia is $101,394.00, according to ZipRecruiter salary data. Most workers in this role earn between $93,700.00 and $109,100.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a senior bioinformatics software engineer?

To thrive as a Senior Bioinformatics Software Engineer, you need a strong background in computer science, biology, and data analysis, often supported by an advanced degree in bioinformatics or a related field. Expertise with programming languages (such as Python, R, or Java), cloud computing, bioinformatics tools, and version control systems is typically required, along with experience using databases and relevant software frameworks. Strong problem-solving skills, collaboration, and effective communication are crucial soft skills for working with multidisciplinary teams and presenting complex data. These combined skills enable the effective development and maintenance of robust software tools that support cutting-edge biological research and data-driven discoveries.

How does a senior bioinformatics software engineer typically collaborate with cross-functional teams in a research or clinical setting?

Senior Bioinformatics Software Engineers frequently work alongside biologists, data scientists, and clinicians to develop and maintain computational pipelines for data analysis. They play a key role in translating complex biological questions into scalable software solutions, often leading code reviews, mentoring junior developers, and ensuring data integrity. Regular meetings and clear communication are vital, as the role requires aligning technical development with scientific goals and regulatory requirements. This collaborative environment offers opportunities to influence project direction and contribute to impactful discoveries.

What does a senior bioinformatics software engineer do?

A Senior Bioinformatics Software Engineer designs, develops, and maintains software tools and pipelines to analyze biological data, such as genomic or proteomic information. They work closely with scientists and researchers to understand data requirements and translate them into efficient, scalable computational solutions. Their responsibilities often include coding, troubleshooting, optimizing algorithms, as well as mentoring junior engineers and contributing to project planning. Senior engineers are expected to have strong programming skills, a solid understanding of bioinformatics concepts, and experience working with large biological datasets.

What is the difference between Senior Bioinformatics Software Engineer vs Bioinformatics Software Engineer?

AspectSenior Bioinformatics Software EngineerBioinformatics Software Engineer
Required CredentialsBachelor's or Master's in Bioinformatics, Computer Science, or related field; experience in software development and bioinformatics toolsBachelor's or Master's in Bioinformatics, Computer Science, or related field; less emphasis on extensive experience
Work EnvironmentResearch labs, biotech companies, healthcare institutions, often leading projectsResearch teams, biotech firms, academic settings, supporting bioinformatics analysis
Employer & Industry UsageUsed in biotech, pharma, healthcare, research institutionsCommon in similar industries, often as entry to mid-level roles

The main difference between a Senior Bioinformatics Software Engineer and a Bioinformatics Software Engineer lies in experience and responsibility. Senior roles typically require more advanced skills, leadership, and project management, while entry-level roles focus on supporting bioinformatics analysis and software development. Both roles are vital in biotech and research industries, but senior positions involve greater oversight and strategic input.

What are the most commonly searched types of Bioinformatics Software Engineer jobs in Virginia? The most popular types of Bioinformatics Software Engineer jobs in Virginia are:
What are popular job titles related to Senior Bioinformatics Software Engineer jobs in Virginia? For Senior Bioinformatics Software Engineer jobs in Virginia, the most frequently searched job titles are:
What job categories do people searching Senior Bioinformatics Software Engineer jobs in Virginia look for? The top searched job categories for Senior Bioinformatics Software Engineer jobs in Virginia are:
What cities in Virginia are hiring for Senior Bioinformatics Software Engineer jobs? Cities in Virginia with the most Senior Bioinformatics Software Engineer job openings:
Senior Bioinformatics Software Engineer jobs near you
Infographic showing various Senior Bioinformatics Software Engineer job openings in Virginia as of August 2026, with employment types broken down into 88% Full Time, 8% Part Time, and 4% Contract. Highlights an 88% Physical, 3% Hybrid, and 9% Remote job distribution, with an average salary of $101,394 per year, or $48.7 per hour.

Senior Software Engineer

Platinum Technologies

Herndon, VA • On-site

$126K - $166K/yr

Full-time

This job post has expired 2 days ago. Applications are no longer accepted.

Job description

Who we are.
Platinum Technologies is a Northern Virginia based integrated solutions firm that specializes in Cybersecurity, Cloud and Digital Services to the Public Sector. Our team solves hard problems and helps our Mission Partners achieve their goals. If you are self-motivated, possess demonstrated learning agility, and are passionate about delivering high-quality work products - we want to hear from you.
We lead with technical expertise, but that is just the tip of the iceberg - the 'Why' matters. At Platinum, we don't hire people to do a job. We provide professional and leadership development to complement our self-motivated domain experts. Our teammates are dot-connecting leaders that operate in a mutually accountable environment to deliver thought leadership, expert technical analysis, and quality execution for our clients.
This position requires an active U.S. Government Security Clearance at the TS/SCI level with CI polygraph.
You.
Platinum Technologies is seeking a Senior Software Engineer to join our team. In this position you will design, develop, integrate, and maintain software applications and services that support Object-Based Intelligence (OBI) mission requirements, enterprise ontologies, and knowledge graph capabilities.
The Senior Software Engineer serves as a key contributor to the design, development, and sustainment of mission-critical software solutions that enable semantic data integration, knowledge management, and advanced analytics. This position develops scalable applications, APIs, and microservices that integrate ontology-driven data models, knowledge graphs, and enterprise data sources to support Object-Based Intelligence workflows. Working within an Agile DevSecOps environment, the Software Engineer collaborates with ontology engineers, database engineers, data scientists, and Government stakeholders to deliver secure, high-performance applications that leverage Semantic Web technologies and AI/ML capabilities.
What you get to do.
  • Design, develop, test, deploy, and maintain software applications and microservices supporting Object-Based Intelligence mission requirements.
  • Develop APIs and backend services that integrate with enterprise ontologies, knowledge graphs, semantic databases, and object-management systems.
  • Implement software solutions that leverage Semantic Web technologies, including RDF, OWL, SPARQL, and graph-based data models, to enable advanced search, reasoning, and data interoperability.
  • Collaborate with ontology engineers, database engineers, data scientists, analysts, and Government stakeholders to translate mission requirements into scalable software solutions.
  • Design and develop secure, containerized applications using modern software engineering practices and cloud-native technologies.
  • Integrate heterogeneous data sources through RESTful APIs, messaging services, and data integration frameworks to support enterprise knowledge management.
  • Develop automated unit, integration, and system tests while supporting continuous integration and continuous deployment (CI/CD) pipelines.
  • Optimize application performance, scalability, and reliability to support high-volume mission operations and advanced analytics.
  • Participate in Agile development activities, including sprint planning, code reviews, technical design sessions, and backlog refinement.
  • Produce and maintain software design documentation, interface specifications, API documentation, and technical implementation guides.
  • Support AI/ML initiatives by developing software services that enable access to semantic data, knowledge graphs, and contextual reasoning capabilities.
  • Provide technical leadership, mentoring, and knowledge transfer activities to Government personnel and project team members on software engineering best practices.

Required Skills.
  • Must be a U.S. citizen and have an active TS/SCI with CI polygraph.
  • Minimum twelve (12) years of experience and an advanced degree or 17 years of experience with a bachelor's degree.
  • Demonstrated experience designing, developing, and maintaining enterprise software applications using modern programming languages such as Java, Python, or C#.
  • Experience developing RESTful APIs, microservices, and distributed applications.
  • Experience integrating applications with relational databases, graph databases, or semantic data platforms.
  • Experience with containerization technologies such as Docker and Kubernetes/OpenShift.
  • Familiarity with Agile software development methodologies, DevSecOps practices, and CI/CD pipelines.
  • Experience with version control systems such as Git.
  • Ability to communicate complex technical concepts effectively to both technical and non-technical stakeholders.

The Company is an Equal Opportunity/Affirmative Action employer. All qualified candidates will receive consideration for employment without regard to disability, protected veteran status, race, color, religious creed, national origin, citizenship, marital status, sex, sexual orientation/gender identity, age, or genetic information.
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

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