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Senior Bioinformatics Software Engineer Jobs in Connecticut

subway

Sr. Software Engineer

Shelton, CT · On-site

$119K - $149K/yr

Sr. Software Engineer (React Native) Ready to build what's next with one of the world's most iconic brands? Why Join Subway? At Subway, we are not standing still. We are building. This is a business ...

subway

Sr. Software Engineer

Shelton, CT · On-site

$119K - $149K/yr

Sr. Software Engineer (React Native) Ready to build what's next with one of the world's most iconic brands? Why Join Subway? At Subway, we are not standing still. We are building. This is a business ...

subway

Sr. Software Engineer

Shelton, CT

$119K - $149K/yr

Sr. Software Engineer (React Native) Ready to build what's next with one of the world's most iconic brands? Why Join Subway? At Subway, we are not standing still. We are building. This is a business ...

subway

Sr. Software Engineer

Shelton, CT

$119K - $149K/yr

Sr. Software Engineer (React Native) Ready to build what's next with one of the world's most iconic brands? Why Join Subway? At Subway, we are not standing still. We are building. This is a business ...

subway

Sr. Software Engineer

Shelton, CT · On-site

$119K - $149K/yr

Sr. Software Engineer (React Native) Ready to build what's next with one of the world's most iconic brands? Why Join Subway? At Subway, we are not standing still. We are building. This is a business ...

subway

Sr. Software Engineer

Shelton, CT

$119K - $149K/yr

Sr. Software Engineer (React Native) Ready to build what's next with one of the world's most iconic brands? Why Join Subway? At Subway, we are not standing still. We are building. This is a business ...

subway

Sr. Software Engineer

Shelton, CT

$119K - $149K/yr

Sr. Software Engineer (React Native) Ready to build what's next with one of the world's most iconic brands? Why Join Subway? At Subway, we are not standing still. We are building. This is a business ...

subway

Sr. Software Engineer

Shelton, CT · On-site

$119K - $149K/yr

Sr. Software Engineer (React Native) Ready to build what's next with one of the world's most iconic brands? Why Join Subway? At Subway, we are not standing still. We are building. This is a business ...

subway

Sr. Software Engineer

Shelton, CT · On-site

$119K - $149K/yr

Sr. Software Engineer (React Native) Ready to build what's next with one of the world's most iconic brands? Why Join Subway? At Subway, we are not standing still. We are building. This is a business ...

subway

Sr. Software Engineer

Shelton, CT · On-site

$119K - $149K/yr

Sr. Software Engineer (React Native) Ready to build what's next with one of the world's most iconic brands? Why Join Subway? At Subway, we are not standing still. We are building. This is a business ...

The Subway

Sr. Software Engineer

Shelton, CT · On-site

$119K - $149K/yr

The Sr. Software Engineer designs, develops, and maintains software solutions that support business and product capabilities. This role contributes to the delivery of reliable, scalable, and ...

subway

Sr. Software Engineer

Shelton, CT · On-site

$119K - $149K/yr

Sr. Software Engineer (React Native) Ready to build what's next with one of the world's most iconic brands? Why Join Subway? At Subway, we are not standing still. We are building. This is a business ...

The Walt Disney Company

Sr Software Engineer

Bristol, CT · On-site

$122K - $161K/yr

Job Posting Title: Sr Software Engineer Req ID: 10151727 Department/Group Overview: Disney Entertainment & ESPN & Technology On any given day at Disney Entertainment & ESPN Technology, we're ...

Labcorp

Senior Software Engineer

Bloomfield, CT

$122K - $161K/yr

Labcorp is seeking a Senior Software Engineer to join our team at our 1302 Hall Boulevard location in Bloomfield, CT! Work Schedule: This is a full time, exempt (salaried) position assigned to a ...

The Walt Disney Company

Sr Software Engineer

Bristol, CT

$148K - $199K/yr

Job Posting Title: Sr Software Engineer Req ID: 10135335 Disney Entertainment and ESPN Product & Technology Technology is at the heart of Disney's past, present, and future. Disney Entertainment and ...

The Walt Disney Company

Sr Software Engineer

Bristol, CT

$122K - $161K/yr

Job Posting Title: Sr Software Engineer Req ID: 10135282 Disney Entertainment and ESPN Product & Technology Technology is at the heart of Disney's past, present, and future. Disney Entertainment and ...

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Senior Bioinformatics Software Engineer information

What are the key skills and qualifications needed to thrive as a senior bioinformatics software engineer?

To thrive as a Senior Bioinformatics Software Engineer, you need a strong background in computer science, biology, and data analysis, often supported by an advanced degree in bioinformatics or a related field. Expertise with programming languages (such as Python, R, or Java), cloud computing, bioinformatics tools, and version control systems is typically required, along with experience using databases and relevant software frameworks. Strong problem-solving skills, collaboration, and effective communication are crucial soft skills for working with multidisciplinary teams and presenting complex data. These combined skills enable the effective development and maintenance of robust software tools that support cutting-edge biological research and data-driven discoveries.

How does a senior bioinformatics software engineer typically collaborate with cross-functional teams in a research or clinical setting?

Senior Bioinformatics Software Engineers frequently work alongside biologists, data scientists, and clinicians to develop and maintain computational pipelines for data analysis. They play a key role in translating complex biological questions into scalable software solutions, often leading code reviews, mentoring junior developers, and ensuring data integrity. Regular meetings and clear communication are vital, as the role requires aligning technical development with scientific goals and regulatory requirements. This collaborative environment offers opportunities to influence project direction and contribute to impactful discoveries.

What does a senior bioinformatics software engineer do?

A Senior Bioinformatics Software Engineer designs, develops, and maintains software tools and pipelines to analyze biological data, such as genomic or proteomic information. They work closely with scientists and researchers to understand data requirements and translate them into efficient, scalable computational solutions. Their responsibilities often include coding, troubleshooting, optimizing algorithms, as well as mentoring junior engineers and contributing to project planning. Senior engineers are expected to have strong programming skills, a solid understanding of bioinformatics concepts, and experience working with large biological datasets.

What is the difference between Senior Bioinformatics Software Engineer vs Bioinformatics Software Engineer?

AspectSenior Bioinformatics Software EngineerBioinformatics Software Engineer
Required CredentialsBachelor's or Master's in Bioinformatics, Computer Science, or related field; experience in software development and bioinformatics toolsBachelor's or Master's in Bioinformatics, Computer Science, or related field; less emphasis on extensive experience
Work EnvironmentResearch labs, biotech companies, healthcare institutions, often leading projectsResearch teams, biotech firms, academic settings, supporting bioinformatics analysis
Employer & Industry UsageUsed in biotech, pharma, healthcare, research institutionsCommon in similar industries, often as entry to mid-level roles

The main difference between a Senior Bioinformatics Software Engineer and a Bioinformatics Software Engineer lies in experience and responsibility. Senior roles typically require more advanced skills, leadership, and project management, while entry-level roles focus on supporting bioinformatics analysis and software development. Both roles are vital in biotech and research industries, but senior positions involve greater oversight and strategic input.

What are the most commonly searched types of Bioinformatics Software Engineer jobs in Connecticut? The most popular types of Bioinformatics Software Engineer jobs in Connecticut are:
What are popular job titles related to Senior Bioinformatics Software Engineer jobs in Connecticut? For Senior Bioinformatics Software Engineer jobs in Connecticut, the most frequently searched job titles are:
What job categories do people searching Senior Bioinformatics Software Engineer jobs in Connecticut look for? The top searched job categories for Senior Bioinformatics Software Engineer jobs in Connecticut are:
Senior Bioinformatics Software Engineer jobs near you
Infographic showing various Senior Bioinformatics Software Engineer job openings in Connecticut as of August 2026, with employment types broken down into 88% Full Time, 8% Part Time, and 4% Contract. Highlights an 88% Physical, 3% Hybrid, and 9% Remote job distribution.

Software Engineer II - Bioinformatics R&D - Remote

SEMA4

Stamford, CT • On-site, Remote

Full-time

Re-posted 29 days ago

Job description

Sema4 is a patient-centered health intelligence company dedicated to advancing healthcare through data-driven insights. Sema4 is transforming healthcare by applying AI and machine learning to multidimensional, longitudinal clinical and genomic data to build dynamic models of human health and defining optimal, individualized health trajectories. Centrellis®, our innovative health intelligence platform, is enabling us to generate a more complete understanding of disease and wellness and to provide science-driven solutions to the most pressing medical needs. Sema4 believes that patients should be treated as partners, and that data should be shared for the benefit of all.
Sema4 is seeking a talented, self-motivated Software Engineer II - Bioinformatics R&D to contribute to cutting-edge translational bioinformatics and clinical product development. As a member of the R&D Bioinformatics department, you will act as a critical member of the Sema4 clinical and research ecosystem focused on innovation, reliability, and quality analysis of high-throughput data at an unprecedented scale. You will use advanced cloud computing technologies to do big data analytics. You will be part of an interdisciplinary team that develops computational methods and pipelines to interpret large-scale human genome and transcriptome sequencing data to understand mutations and mutation processes in cancer and reproductive health and to translate that understanding to clinical utility. You will develop systems for integrating novel informatics and genomics tools and methodologies into clinical products and practices.
RESPONSIBILITIES
  • Carry out software design, coding, testing, debugging, and documentation
  • Automate existing analysis workflows, migrate existing workflows to cloud platforms, and develop new workflows and pipelines for clinical and research projects
  • Develop, implement, and follow best practices in software development, code versioning, software testing, and deployment
  • Collaborate closely with scientists, clinicians, and product managers to design, engineer, and implement analytics pipeline solutions in the Amazon AWS cloud environment
  • Deliver high-quality, well-tested software to the production bioinformatics team for use in clinical products
  • Contribute to bioinformatics research analysis
  • Communicate effectively with collaborators (computational and bioinformatics scientists on R&D and production teams, IT/HPC, clinical lab directors, knowledgebase and curation teams, wet lab staff) to understand and satisfy product and research analysis needs
  • Train and provide support for bioinformatics scientists and other team members in internally developed best practices for software development, testing, and software development lifecycle (SDLC) policies

QUALIFICATIONS
  • M.S. in Computer Science, Computer Engineering, Bioinformatics, Computational Biology, or related fields. B.S. plus equivalent experience will be considered
  • 2+ years of post-graduate software development experience
  • Working in a team, self-motivation, ability to manage multiple tasks simultaneously, ability to solve problems independently
  • Possess strong understanding of computer science fundamentals, algorithms, and software engineering best practices
  • Strong coding proficiency in Python and R programming languages or similar. Experience with multiple coding languages such as Java/Scala is preferred.
  • Programming experience in Unix/Linux environment
  • Experience with Docker or similar software container platform
  • Hands-on experience working with NGS and bioinformatics tools will be a plus, especially GATK and WDL and common NGS data formats (VCF, BAM)
  • Experience working with cloud computing infrastructures will be a plus, especially on Amazon AWS and DNAnexus
  • Developing codebases using distributed version control tools (especially Git) and software issue tracking systems (especially Jira)
  • Excellent communication and interpersonal skills needed for working in an interdisciplinary team of scientists, engineers, and clinicians
  • Well-versed in the art of effective technical communication, especially graphical communication, about systems design and high-complexity datasets

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