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Senior Bioinformatics Software Engineer Jobs in Missouri

Bioinformatics Engineer II

California, MO ยท On-site

$90K - $140K/yr

## Bioinformatics Engineer IIApplylocations: Remote - Californiatime type: Full timeposted on: Posted Yesterdayjob requisition id: JR202600797**Compensation:**Pay Range: $90,000 - $140,000

LocationSAINT LOUIS, MO 63110 Scheduled Hours 40 Position SummaryThe Orr Lab is seeking support for computational and quantitative research focused on aging, neurodegeneration, and human disease. The

$55K - $100K/yr

LocationST. LOUIS, MO 63110 Scheduled Hours 40 Position SummaryAssists in developing and conducting research projects, including experiment design, data analysis, and documentation of experiment

Senior Software Engineer

O Fallon, MO ยท On-site

$114K - $151K/yr

Our Purpose Mastercard powers economies and empowers people in 200+ countries and territories worldwide. Together with our customers, we're helping build asustainableeconomy where everyone can

Senior Software Engineer

O Fallon, MO ยท On-site

$114K - $151K/yr

Our Purpose Mastercard powers economies and empowers people in 200+ countries and territories worldwide. Together with our customers, we're helping build a sustainable economy where everyone can

Senior Software Engineer

Kansas City, MO ยท On-site

$119K - $157K/yr

Description Senior Software Engineer - Aerospace & Defense Test Systems Location: Kansas City, MO Job Type: Full-Time Industry: Aerospace, Defense, Automated Test Equipment Citizenship Requirement:

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Showing results 1-20

Senior Bioinformatics Software Engineer information

See Missouri salary details

$79.3K

$95.9K

$112.1K

How much do senior bioinformatics software engineer jobs pay per year?

As of Sep 13, 2026, the average yearly pay for senior bioinformatics software engineer in Missouri is $95,931.00, according to ZipRecruiter salary data. Most workers in this role earn between $88,600.00 and $103,200.00 per year, depending on experience, location, and employer.

What does a senior bioinformatics software engineer do?

A Senior Bioinformatics Software Engineer designs, develops, and maintains software tools and pipelines to analyze biological data, such as genomic or proteomic information. They work closely with scientists and researchers to understand data requirements and translate them into efficient, scalable computational solutions. Their responsibilities often include coding, troubleshooting, optimizing algorithms, as well as mentoring junior engineers and contributing to project planning. Senior engineers are expected to have strong programming skills, a solid understanding of bioinformatics concepts, and experience working with large biological datasets.

What are the key skills and qualifications needed to thrive as a senior bioinformatics software engineer?

To thrive as a Senior Bioinformatics Software Engineer, you need a strong background in computer science, biology, and data analysis, often supported by an advanced degree in bioinformatics or a related field. Expertise with programming languages (such as Python, R, or Java), cloud computing, bioinformatics tools, and version control systems is typically required, along with experience using databases and relevant software frameworks. Strong problem-solving skills, collaboration, and effective communication are crucial soft skills for working with multidisciplinary teams and presenting complex data. These combined skills enable the effective development and maintenance of robust software tools that support cutting-edge biological research and data-driven discoveries.

How does a senior bioinformatics software engineer typically collaborate with cross-functional teams in a research or clinical setting?

Senior Bioinformatics Software Engineers frequently work alongside biologists, data scientists, and clinicians to develop and maintain computational pipelines for data analysis. They play a key role in translating complex biological questions into scalable software solutions, often leading code reviews, mentoring junior developers, and ensuring data integrity. Regular meetings and clear communication are vital, as the role requires aligning technical development with scientific goals and regulatory requirements. This collaborative environment offers opportunities to influence project direction and contribute to impactful discoveries.

What is the difference between Senior Bioinformatics Software Engineer vs Bioinformatics Software Engineer?

AspectSenior Bioinformatics Software EngineerBioinformatics Software Engineer
Required CredentialsBachelor's or Master's in Bioinformatics, Computer Science, or related field; experience in software development and bioinformatics toolsBachelor's or Master's in Bioinformatics, Computer Science, or related field; less emphasis on extensive experience
Work EnvironmentResearch labs, biotech companies, healthcare institutions, often leading projectsResearch teams, biotech firms, academic settings, supporting bioinformatics analysis
Employer & Industry UsageUsed in biotech, pharma, healthcare, research institutionsCommon in similar industries, often as entry to mid-level roles

The main difference between a Senior Bioinformatics Software Engineer and a Bioinformatics Software Engineer lies in experience and responsibility. Senior roles typically require more advanced skills, leadership, and project management, while entry-level roles focus on supporting bioinformatics analysis and software development. Both roles are vital in biotech and research industries, but senior positions involve greater oversight and strategic input.

What are the most commonly searched types of Bioinformatics Software Engineer jobs in Missouri?

The most popular types of Bioinformatics Software Engineer jobs in Missouri are:

What cities in Missouri are hiring for Senior Bioinformatics Software Engineer jobs?

Cities in Missouri with the most Senior Bioinformatics Software Engineer job openings:

Infographic showing various Senior Bioinformatics Software Engineer job openings in Missouri as of August 2026, with employment types broken down into 88% Full Time, 8% Part Time, and 4% Contract. Highlights an 88% Physical, 3% Hybrid, and 9% Remote job distribution, with an average salary of $95,931 per year, or $46.1 per hour.