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Operations Excellence Manager Jobs in Raleigh, NC

Clorox

Process Manager - S&OE, Centralized

Durham, NC · On-site

... Excellence Manager, driving stakeholder engagement, leadership buy-in, and prioritization of process and system improvements. * What we look for: * Supply Chain Operations: Comprehension of CPG ...

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Ulta Beauty, Inc.

Operations Manager

Apex, NC · On-site

This position requires a passion for operational excellence, a drive for results, the ability to ... Support all aspects of manager and associate professional development, including training ...

Ulta Beauty, Inc.

Operations Manager

Apex, NC · On-site

This position requires a passion for operational excellence, a drive for results, the ability to ... Support all aspects of manager and associate professional development, including training ...

Ulta Beauty, Inc.

Operations Manager

Chapel Hill, NC · On-site

This position requires a passion for operational excellence, a drive for results, the ability to ... Support all aspects of manager and associate professional development, including training ...

Ulta Beauty, Inc.

Operations Manager

Chapel Hill, NC · On-site

This position requires a passion for operational excellence, a drive for results, the ability to ... Support all aspects of manager and associate professional development, including training ...

Ulta Beauty

Operations Manager

Apex, NC · On-site

This position requires a passion for operational excellence, a drive for results, the ability to ... Support all aspects of manager and associate professional development, including training ...

Wind River Environmental LLC

Operations Manager

Durham, NC · On-site

$115K - $140K/yr

Join a growing, essential services company with a reputation for operational excellence. * Drive a ... Manage branch P&L, budgets, and operational plans to meet revenue and profit targets. * Track ...

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All JobsOperations Excellence JobsOperations Excellence Manager JobsOperations Excellence Manager Jobs in Raleigh, NC

Operations Excellence Manager information

See Raleigh, NC salary details

$30.1K

$61.7K

$115.2K

How much do operations excellence manager jobs pay per year?

As of Aug 2, 2026, the average yearly pay for operations excellence manager in Raleigh, NC is $61,681.00, according to ZipRecruiter salary data. Most workers in this role earn between $39,900.00 and $75,300.00 per year, depending on experience, location, and employer.

What is the difference between Operations Excellence Manager vs Continuous Improvement Manager?

AspectOperations Excellence ManagerContinuous Improvement Manager
CredentialsTypically requires a bachelor's degree in engineering, business, or related field; certifications like Lean, Six Sigma are commonSimilar credentials; Lean, Six Sigma certifications often preferred
Work EnvironmentWorks across departments to optimize processes, often in manufacturing or large organizationsFocuses on process improvements, often in manufacturing, healthcare, or service industries
Employer & Industry UsageUsed by companies aiming for operational efficiency and quality improvementsUsed by organizations seeking continuous process enhancements and waste reduction

The Operations Excellence Manager and Continuous Improvement Manager roles share similar credentials and work environments, focusing on process optimization. However, the Operations Excellence Manager often has a broader scope, overseeing multiple initiatives across departments, while the Continuous Improvement Manager concentrates specifically on ongoing process improvements. Both roles are vital for organizations committed to operational efficiency and quality enhancement.

How does an Operations Excellence Manager typically collaborate with cross-functional teams to drive process improvements?

An Operations Excellence Manager regularly works alongside departments such as production, quality, supply chain, and IT to identify inefficiencies and develop improvement strategies. This collaboration often involves facilitating workshops, leading process mapping sessions, and coordinating with team leads to implement best practices. Through effective communication and change management, the Operations Excellence Manager ensures alignment of goals and fosters a culture of continuous improvement across the organization.

What are the key skills and qualifications needed to thrive as an Operations Excellence Manager, and why are they important?

To thrive as an Operations Excellence Manager, you need a strong background in process improvement, data analysis, and project management, typically supported by a degree in business, engineering, or a related field. Familiarity with Lean, Six Sigma methodologies, and ERP or process mapping software—as well as relevant certifications like Lean Six Sigma Green Belt or Black Belt—is often required. Exceptional leadership, communication, and change management skills set top performers apart in this role. These skills are crucial for driving operational efficiency, fostering team alignment, and sustaining continuous improvement initiatives across the organization.

What does an Operations Excellence Manager do?

An Operations Excellence Manager is responsible for improving business processes to enhance efficiency, quality, and productivity within an organization. They analyze current operational procedures, identify areas for improvement, and implement best practices and Lean methodologies. Their goal is to streamline operations, reduce costs, and ensure high standards of performance across departments. They often lead cross-functional teams and drive continuous improvement initiatives to achieve organizational goals.
What are the most commonly searched types of Operations Excellence jobs in Raleigh, NC? The most popular types of Operations Excellence jobs in Raleigh, NC are:
What are popular job titles related to Operations Excellence Manager jobs in Raleigh, NC? For Operations Excellence Manager jobs in Raleigh, NC, the most frequently searched job titles are:
What job categories do people searching Operations Excellence Manager jobs in Raleigh, NC look for? The top searched job categories for Operations Excellence Manager jobs in Raleigh, NC are:
What cities near Raleigh, NC are hiring for Operations Excellence Manager jobs? Cities near Raleigh, NC with the most Operations Excellence Manager job openings:
Operations Excellence Manager jobs near you
Infographic showing various Operations Excellence Manager job openings in Raleigh, NC as of July 2026, with employment types broken down into 1% As Needed, 81% Full Time, 15% Part Time, and 3% Contract. Highlights an 95% Physical, 2% Hybrid, and 3% Remote job distribution, with an average salary of $61,681 per year, or $29.7 per hour.

Associate Director, Operational Excellence #4890

GRAIL

Durham, NC

$146K - $194K/yr

Full-time

Posted 12 days ago

Job description

Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.
 
We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.
 
GRAIL is headquartered in the bay area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.
 
For more information, please visit grail.com

The Associate Director, Operational Excellence is central to driving continuous improvement, operational rigor, and data-informed decision-making across laboratory and operational workflows.  The ideal candidate combines deep analytical capability with proven experience in Lean methodologies and cross-functional leadership.  They will play a critical role in transforming operational data into actionable insights, enabling scalable, high-quality execution in a regulated environment.

This role works on-site full-time at our office located in Durham, NC

Responsibilities:
  • Operational Data & Insights
    • Design, develop, and maintain operational dashboards and data visualizations to provide real-time visibility into performance
    • Generate and distribute KPI reports, ensuring clarity, accuracy, and alignment with organizational goals
    • Partner with stakeholders to define meaningful metrics and continuously improve reporting frameworks
  • Data Exploration & Process Monitoring
    • Conduct deep data analysis to identify trends, anomalies, and leading indicators related to Statistical Process Control (SPC) and Quality Control (QC)
    • Establish and refine control limits, early warning systems, and predictive indicators to proactively manage operational risk
    • Translate complex data findings into clear, actionable recommendations
  • Continuous Improvement Leadership
    • Lead and scale Lean initiatives, including 5S, Six Sigma, and Kaizen programs, across operational teams
    • Drive a culture of continuous improvement through structured problem-solving and iterative refinement of processes
    • Measure and track the impact of improvement initiatives, ensuring sustained gains
  • Issue Management & Prioritization
    • Develop and maintain a centralized system for capturing operational issues, risks, and improvement opportunities
    • Synthesize inputs across teams into a structured backlog of initiatives
    • Partner with cross-functional stakeholders (e.g., Engineering, Software, Lab) to prioritize and align on improvement efforts
  • Cross-Functional Collaboration
    • Act as a key liaison between Operations and non-Operations teams to drive execution of improvement initiatives
    • Ensure alignment on priorities, timelines, and expected outcomes
    • Influence without authority to remove barriers and accelerate progress
Required Qualifications:
  • Bachelor’s degree in Engineering, Life Sciences, Operations, Data Science, or related field (advanced degree preferred)
  • 12+ years of experience in operational excellence, process improvement, or analytics, ideally in biotech, diagnostics, or regulated environments
  • Demonstrated expertise in Lean, Six Sigma (Green Belt or Black Belt preferred), and Kaizen methodologies
  • Strong experience with data visualization tools (e.g., Tableau, Power BI, Looker) and data analysis (SQL, Python, R, or similar)
  • Proven ability to work with SPC/QC frameworks and operational performance metrics
  • Experience leading cross-functional initiatives and influencing senior stakeholders
  • Excellent problem-solving, communication, and organizational skills
  • Experience in NGS, clinical laboratory operations, or diagnostics workflows
  • Familiarity with regulated environments (CLIA, CAP, FDA) preferred
Physical Demands and Work Environment
  • Work performed across office, production, and executive settings.
  • Exposure to manufacturing environments, including noise, chemicals, and production equipment.
  • Extended or flexible hours may be required to meet organizational goals.
  • Use of personal protective equipment (PPE), including safety glasses, gloves, and hearing protection, required in designated areas.
The expected, full-time, annual base pay scale for this position is $146K - $194K.  Actual base pay will consider skills, experience, and location.

This role may be eligible for other forms of compensation, including an annual bonus and/or incentives, subject to the terms of the applicable plans and Company discretion. This range reflects a good-faith estimate of the range that the Company reasonably expects to pay for the position upon hire; the actual compensation offered may vary depending on factors such as the candidate’s qualifications. Employees in this role are also eligible for GRAIL’s comprehensive and competitive benefits package, offered in accordance with our applicable plans and policies. This package currently includes flexible time-off or vacation; a 401(k) retirement plan with employer match; medical, dental, and vision coverage; and carefully selected mindfulness programs.
 
GRAIL is an equal employment opportunity employer, and we are committed to building a workplace where every individual can thrive, contribute, and grow. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, gender, gender identity, sexual orientation, age, disability, status as a protected veteran, , or any other class or characteristic protected by applicable federal, state, and local laws. Additionally, GRAIL will consider for employment qualified applicants with arrest and conviction records in a manner consistent with applicable law and provide reasonable accommodations to qualified individuals with disabilities. Please contact us at rc@grailbio.com if you require an accommodation to apply for an open position.
 
GRAIL maintains a drug-free workplace. We welcome job-seekers from all backgrounds to join us!