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Operational Excellence Jobs in Raleigh, NC (NOW HIRING)

GRAIL

Engineer, Operational Excellence #4892

Durham, NC · On-site

$69K - $93K/yr

For more information, please visit grail.com The Engineer, Operational Excellence will support continuous improvement initiatives within our sequencing-based cancer screening operations. This role ...

GRAIL

Engineer Operational Excellence #4893

Durham, NC · On-site

$69K - $93K/yr

For more information, please visit grail.com The Engineer, Operational Excellence will support continuous improvement initiatives within our sequencing-based cancer screening operations. This role ...

GRAIL

Engineer Operational Excellence #4893

Durham, NC

$69K - $93K/yr

For more information, please visit grail.com The Engineer, Operational Excellence will support continuous improvement initiatives within our sequencing-based cancer screening operations. This role ...

GRAIL

Engineer, Operational Excellence #4892

Durham, NC · On-site

$69K - $93K/yr

For more information, please visit grail.com The Engineer, Operational Excellence will support continuous improvement initiatives within our sequencing-based cancer screening operations. This role ...

GRAIL

Engineer Operational Excellence #4893

Durham, NC

$69K - $93K/yr

For more information, please visit grail.com The Engineer, Operational Excellence will support continuous improvement initiatives within our sequencing-based cancer screening operations. This role ...

GRAIL

Engineer, Operational Excellence #4892

Durham, NC · On-site

$69K - $93K/yr

For more information, please visit grail.com The Engineer, Operational Excellence will support continuous improvement initiatives within our sequencing-based cancer screening operations. This role ...

Flowserve

NAM Operational Excellence Leader

Raleigh, NC · On-site

The NAM Operational Excellence Leader will lead a consistent and rapid LEAN deployment, providing leadership for CI initiatives, assessing current business performance, identifying gaps, establishing ...

Flowserve

NAM Operational Excellence Leader

Raleigh, NC · On-site

The NAM Operational Excellence Leader will lead a consistent and rapid LEAN deployment, providing leadership for CI initiatives, assessing current business performance, identifying gaps, establishing ...

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Operational Excellence information

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How much do operational excellence jobs pay per hour?

As of Aug 2, 2026, the average hourly pay for operational excellence in Raleigh, NC is $20.71, according to ZipRecruiter salary data. Most workers in this role earn between $16.35 and $23.61 per hour, depending on experience, location, and employer.

What types of projects or initiatives does someone in Operational Excellence typically lead or participate in?

Professionals in Operational Excellence are often involved in projects that focus on streamlining business processes, reducing waste, and increasing quality and efficiency across departments. Typical initiatives might include leading value stream mapping sessions, conducting root cause analyses, facilitating Kaizen events, and implementing new best practices or technologies to optimize workflow. These roles frequently require cross-functional collaboration with teams in production, quality, supply chain, finance, and IT to drive impactful change. Depending on the organization, you may also be responsible for training teams on process improvement methodologies and tracking the measurable results of these efforts.

What does an Operational Excellence job entail?

An Operational Excellence job focuses on improving business processes, efficiency, and overall performance by implementing best practices, data-driven decision-making, and continuous improvement methodologies like Lean or Six Sigma. Professionals in this role work to optimize workflows, reduce waste, and enhance productivity across various departments. They collaborate with leadership teams to drive a culture of continuous improvement and operational efficiency.

What are the key skills and qualifications needed to thrive in the Operational Excellence position, and why are they important?

To thrive in Operational Excellence, you need a solid understanding of process improvement methodologies (like Lean or Six Sigma), data analysis, and change management, often backed by relevant certifications such as Lean Six Sigma Green or Black Belt. Familiarity with analytical and process mapping tools like Microsoft Visio, Minitab, and ERP systems is highly beneficial. Exceptional communication, leadership, and problem-solving abilities are vital for driving cross-functional initiatives and engaging teams. These skills are crucial for identifying inefficiencies, implementing sustainable improvements, and fostering a culture of continuous improvement within an organization.

What are the most commonly searched types of Operational Excellence jobs in Raleigh, NC? The most popular types of Operational Excellence jobs in Raleigh, NC are:
What job categories do people searching Operational Excellence jobs in Raleigh, NC look for? The top searched job categories for Operational Excellence jobs in Raleigh, NC are:
What cities near Raleigh, NC are hiring for Operational Excellence jobs? Cities near Raleigh, NC with the most Operational Excellence job openings:
Operational Excellence jobs near you
Infographic showing various Operational Excellence job openings in Raleigh, NC as of July 2026, with employment types broken down into 1% As Needed, 81% Full Time, 15% Part Time, and 3% Contract. Highlights an 95% Physical, 2% Hybrid, and 3% Remote job distribution, with an average salary of $43,070 per year, or $20.7 per hour.

Engineer, Operational Excellence #4892

GRAIL

Durham, NC • On-site

$69K - $93K/yr

Full-time

Posted 12 days ago

Job description

Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.
 
We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.
 
GRAIL is headquartered in the bay area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.
 
For more information, please visit grail.com

The Engineer, Operational Excellence will support continuous improvement initiatives within our sequencing-based cancer screening operations. This role will work at the intersection of data, process, and operations to enhance efficiency, quality, and scalability across laboratory and operational workflows. The ideal candidate is detail-oriented, data-savvy, and experienced in Lean methodologies, with a strong inclination toward solving complex operational problems through structured analysis and experimentation.

This role works on-site full-time at our office located in Durham, NC

Responsibilities:

  • Operational Data & Reporting

    • Support generation and automation of KPI reporting, ensuring data integrity and usability

    • Collaborate with stakeholders to refine metrics and improve visibility into operational performance

  • Process Analysis & Monitoring

    • Perform data exploration and statistical analysis to identify trends, variation, and potential process deviations

    • Apply Statistical Process Control (SPC) and Quality Control (QC) methods to monitor and improve process stability

  • Continuous Improvement Execution

    • Execute and support Lean initiatives, including 5S, Kaizen events, and Six Sigma projects

    • Partner with operations teams to pilot, measure, and scale process improvements

  • Issue Tracking & Prioritization Support

    • Capture and document operational issues, risks, and improvement opportunities

    • Support prioritization of improvement efforts in collaboration with cross-functional stakeholders

  • Cross-Functional Collaboration

    • Work closely with Operations, Engineering, Software, and Product teams to implement process improvements

Required Qualifications:
  • Bachelor’s degree in Engineering, Life Sciences, Industrial Engineering, or related field
  • 3+ years of experience in process engineering, operations, or continuous improvement roles, ideally in biotech, diagnostics, or manufacturing
  • Working knowledge of Lean, Six Sigma, and Kaizen methodologies (certification a plus)
  • Experience with data analysis and visualization tools (e.g., Excel, SQL, Python, Tableau, Power BI)
  • Familiarity with SPC/QC tools and statistical analysis techniques
  • Strong problem-solving skills with attention to detail and data accuracy
  • Effective communicator with the ability to collaborate across teams
Preferred Qualifications:
  • Strong problem-solving skills with attention to detail and data accuracy
  • Effective communicator with the ability to collaborate across teams
Physical Demands and Work Environment
  • Work performed across office, production, and executive settings.
  • Exposure to manufacturing environments, including noise, chemicals, and production equipment.
  • Extended or flexible hours may be required to meet organizational goals.
  • Use of personal protective equipment (PPE), including safety glasses, gloves, and hearing protection, required in designated areas.
The expected, full-time, annual base pay scale for this position is $69K - $93K.  Actual base pay will consider skills, experience, and location.

This role may be eligible for other forms of compensation, including an annual bonus and/or incentives, subject to the terms of the applicable plans and Company discretion. This range reflects a good-faith estimate of the range that the Company reasonably expects to pay for the position upon hire; the actual compensation offered may vary depending on factors such as the candidate’s qualifications. Employees in this role are also eligible for GRAIL’s comprehensive and competitive benefits package, offered in accordance with our applicable plans and policies. This package currently includes flexible time-off or vacation; a 401(k) retirement plan with employer match; medical, dental, and vision coverage; and carefully selected mindfulness programs.
 
GRAIL is an equal employment opportunity employer, and we are committed to building a workplace where every individual can thrive, contribute, and grow. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, gender, gender identity, sexual orientation, age, disability, status as a protected veteran, , or any other class or characteristic protected by applicable federal, state, and local laws. Additionally, GRAIL will consider for employment qualified applicants with arrest and conviction records in a manner consistent with applicable law and provide reasonable accommodations to qualified individuals with disabilities. Please contact us at rc@grailbio.com if you require an accommodation to apply for an open position.
 
GRAIL maintains a drug-free workplace. We welcome job-seekers from all backgrounds to join us!